{"id":"https://openalex.org/W2146179241","doi":"https://doi.org/10.1093/bioinformatics/btk026","title":"A multi-step approach to time series analysis and gene expression clustering","display_name":"A multi-step approach to time series analysis and gene expression clustering","publication_year":2006,"publication_date":"2006-01-05","ids":{"openalex":"https://openalex.org/W2146179241","doi":"https://doi.org/10.1093/bioinformatics/btk026","mag":"2146179241","pmid":"https://pubmed.ncbi.nlm.nih.gov/16397005"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btk026","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btk026","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075993058","display_name":"Roberto Amato","orcid":"https://orcid.org/0000-0001-8633-9221"},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Amato","raw_affiliation_strings":["Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083215657","display_name":"Angelo Ciaramella","orcid":"https://orcid.org/0000-0001-5592-7995"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Ciaramella","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","institution_ids":["https://openalex.org/I131729948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049632510","display_name":"N. Deniskina","orcid":"https://orcid.org/0000-0003-2730-6395"},"institutions":[{"id":"https://openalex.org/I4210107660","display_name":"Institute for Information Transmission Problems","ror":"https://ror.org/013w2d378","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210107660"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT","RU"],"is_corresponding":false,"raw_author_name":"N. Deniskina","raw_affiliation_strings":["Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","Institute of Information Transmission Problems, Russian Academy of Sciences 3 \u00a0 3 \u00a0 \u00a0 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Institute of Information Transmission Problems, Russian Academy of Sciences 3 \u00a0 3 \u00a0 \u00a0 Moscow, Russia","institution_ids":["https://openalex.org/I4210107660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033290145","display_name":"Carmine Del Mondo","orcid":null},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C. Del Mondo","raw_affiliation_strings":["Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001896455","display_name":"Diego di Bernardo","orcid":"https://orcid.org/0000-0002-1911-7407"},"institutions":[{"id":"https://openalex.org/I4210152213","display_name":"Telethon Institute Of Genetics And Medicine","ror":"https://ror.org/04xfdsg27","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210152213","https://openalex.org/I4210154366"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. di Bernardo","raw_affiliation_strings":["Telethon Institute of Genetics and Medicine 4 \u00a0 4 \u00a0 \u00a0 Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Telethon Institute of Genetics and Medicine 4 \u00a0 4 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I4210152213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023621519","display_name":"C. Donalek","orcid":null},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"C. Donalek","raw_affiliation_strings":["Department of Astronomy, California Institute of Technology 5 \u00a0 5 \u00a0 \u00a0 Pasadena CA, USA","Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Astronomy, California Institute of Technology 5 \u00a0 5 \u00a0 \u00a0 Pasadena CA, USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028392415","display_name":"G. Longo","orcid":"https://orcid.org/0000-0002-9182-8414"},"institutions":[{"id":"https://openalex.org/I4210108560","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Napoli","ror":"https://ror.org/015kcdd40","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210108560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]},{"id":"https://openalex.org/I875825670","display_name":"National Institute for Astrophysics","ror":"https://ror.org/02gh4kt33","country_code":"IT","type":"funder","lineage":["https://openalex.org/I875825670"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Longo","raw_affiliation_strings":["Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","INAF\u2014Istituto Nazionale di Astrofisica 7 \u00a0 7 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"INAF\u2014Istituto Nazionale di Astrofisica 7 \u00a0 7 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I875825670"]},{"raw_affiliation_string":"INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I4210108560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076667011","display_name":"G. Mangano","orcid":null},"institutions":[{"id":"https://openalex.org/I4210108560","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Napoli","ror":"https://ror.org/015kcdd40","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210108560"]},{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"G. Mangano","raw_affiliation_strings":["Department of Physics, Syracuse University 8 \u00a0 8 \u00a0 \u00a0 Syracuse NY, USA","Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Syracuse University 8 \u00a0 8 \u00a0 \u00a0 Syracuse NY, USA","institution_ids":["https://openalex.org/I70983195"]},{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I4210108560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043315785","display_name":"Gennaro Miele","orcid":"https://orcid.org/0000-0002-2028-0578"},"institutions":[{"id":"https://openalex.org/I4210108560","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Napoli","ror":"https://ror.org/015kcdd40","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210108560"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Miele","raw_affiliation_strings":["Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I4210108560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087862725","display_name":"Giancarlo Raiconi","orcid":"https://orcid.org/0000-0001-5307-7173"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]},{"id":"https://openalex.org/I4210108560","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Napoli","ror":"https://ror.org/015kcdd40","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210108560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Raiconi","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I4210108560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026753803","display_name":"Antonino Staiano","orcid":"https://orcid.org/0000-0002-4708-5860"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Staiano","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"Dipartimento di Scienze Fisiche, University of Naples \u2018Federico II\u2019 1 \u00a0 1 \u00a0 \u00a0 Naples, ITALY","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030668200","display_name":"Roberto Tagliaferri","orcid":"https://orcid.org/0000-0001-8134-9025"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]},{"id":"https://openalex.org/I4210108560","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Napoli","ror":"https://ror.org/015kcdd40","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210108560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Tagliaferri","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, University of Salerno 2 \u00a0 2 \u00a0 \u00a0 Fisciano, Salerno, ITALY","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"INFN\u2014Istituto Nazionale Fisica Nucleare 6 \u00a0 6 \u00a0 \u00a0 Sezione di Napoli, Naples, ITALY","institution_ids":["https://openalex.org/I4210108560"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.1366,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.91750445,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"22","issue":"5","first_page":"589","last_page":"596"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.4771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.4771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12205","display_name":"Time Series Analysis and Forecasting","score":0.2587999999523163,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13487","display_name":"Statistical and numerical algorithms","score":0.03680000081658363,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7886046171188354},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.7182860970497131},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6976913809776306},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4620247781276703},{"id":"https://openalex.org/keywords/a-priori-and-a-posteriori","display_name":"A priori and a posteriori","score":0.4597836136817932},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.4581349194049835},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.45117491483688354},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.4477887749671936},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.44167301058769226},{"id":"https://openalex.org/keywords/time-series","display_name":"Time series","score":0.44101932644844055},{"id":"https://openalex.org/keywords/hierarchical-clustering","display_name":"Hierarchical clustering","score":0.428242027759552},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4199039340019226},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.41367512941360474}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7886046171188354},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.7182860970497131},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6976913809776306},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4620247781276703},{"id":"https://openalex.org/C75553542","wikidata":"https://www.wikidata.org/wiki/Q178161","display_name":"A priori and a posteriori","level":2,"score":0.4597836136817932},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4581349194049835},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.45117491483688354},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.4477887749671936},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.44167301058769226},{"id":"https://openalex.org/C151406439","wikidata":"https://www.wikidata.org/wiki/Q186588","display_name":"Time series","level":2,"score":0.44101932644844055},{"id":"https://openalex.org/C92835128","wikidata":"https://www.wikidata.org/wiki/Q1277447","display_name":"Hierarchical clustering","level":3,"score":0.428242027759552},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4199039340019226},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.41367512941360474},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btk026","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btk026","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16397005","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16397005","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:ricerca.uniparthenope.it:11367/16418","is_oa":false,"landing_page_url":"http://hdl.handle.net/11367/16418","pdf_url":null,"source":{"id":"https://openalex.org/S4377196432","display_name":"CINECA IRIS Institutial research information system (Parthenope University of Naples)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I183638586","host_organization_name":"Parthenope University of Naples","host_organization_lineage":["https://openalex.org/I183638586"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","score":0.5199999809265137,"id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324133","display_name":"Universit\u00e0 degli Studi di Salerno","ror":"https://ror.org/0192m2k53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W99903558","https://openalex.org/W1480376833","https://openalex.org/W1502713942","https://openalex.org/W1548802052","https://openalex.org/W1554663460","https://openalex.org/W1648310010","https://openalex.org/W1679913846","https://openalex.org/W1970993238","https://openalex.org/W1984121966","https://openalex.org/W1989297334","https://openalex.org/W2002016471","https://openalex.org/W2002810210","https://openalex.org/W2025410493","https://openalex.org/W2027514721","https://openalex.org/W2039741009","https://openalex.org/W2049633694","https://openalex.org/W2074033194","https://openalex.org/W2087573762","https://openalex.org/W2091879895","https://openalex.org/W2096758922","https://openalex.org/W2099114361","https://openalex.org/W2103453943","https://openalex.org/W2107636931","https://openalex.org/W2123902215","https://openalex.org/W2125512776","https://openalex.org/W2135187880","https://openalex.org/W2141144953","https://openalex.org/W2142460132","https://openalex.org/W2144710927","https://openalex.org/W2146264532","https://openalex.org/W2146646206","https://openalex.org/W2148541040","https://openalex.org/W2150926065","https://openalex.org/W2155120241","https://openalex.org/W2155903894","https://openalex.org/W2155974384","https://openalex.org/W2158096909","https://openalex.org/W2161168841","https://openalex.org/W2162143426","https://openalex.org/W2168394301","https://openalex.org/W2170700353","https://openalex.org/W2313803192","https://openalex.org/W2410083255","https://openalex.org/W2799061466","https://openalex.org/W3099514962","https://openalex.org/W3101312859","https://openalex.org/W3104811334","https://openalex.org/W4205687621","https://openalex.org/W4205778870","https://openalex.org/W4213332169","https://openalex.org/W4233622718","https://openalex.org/W4239901699","https://openalex.org/W4250857377","https://openalex.org/W4388297464","https://openalex.org/W6604069481","https://openalex.org/W6643029403","https://openalex.org/W6683411047","https://openalex.org/W6683467955","https://openalex.org/W6699022684"],"related_works":["https://openalex.org/W2068608913","https://openalex.org/W4388311650","https://openalex.org/W5922282","https://openalex.org/W1974056099","https://openalex.org/W4245343541","https://openalex.org/W2386077341","https://openalex.org/W563589758","https://openalex.org/W62490179","https://openalex.org/W2954004777","https://openalex.org/W2951102138"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1,60,112],"huge":[2],"growth":[3],"in":[4,33,93],"gene":[5,57],"expression":[6],"data":[7,16,29,72,136],"calls":[8],"for":[9,15,39],"the":[10,88,94,103,107,121,130],"implementation":[11],"of":[12,90,106,120],"automatic":[13,79],"tools":[14],"processing":[17],"and":[18,25,42,76,98,124],"interpretation.":[19],"RESULTS:":[20],"We":[21],"present":[22,92],"a":[23,34,64,85,99,117],"new":[24],"comprehensive":[26],"machine":[27],"learning":[28],"mining":[30],"framework":[31],"consisting":[32],"non-linear":[35],"PCA":[36],"neural":[37],"network":[38],"feature":[40],"extraction,":[41],"probabilistic":[43],"principal":[44],"surfaces":[45],"combined":[46],"with":[47,73,83],"an":[48,78],"agglomerative":[49],"approach":[50],"based":[51],"on":[52,70],"Negentropy":[53],"aimed":[54],"at":[55,139],"clustering":[56],"microarray":[58],"data.":[59,95],"method,":[61],"which":[62],"provides":[63],"user-friendly":[65],"visualization":[66],"interface,":[67],"can":[68],"work":[69],"noisy":[71],"missing":[74],"points":[75],"represents":[77],"procedure":[80],"to":[81],"get,":[82],"no":[84],"priori":[86],"assumptions,":[87],"number":[89],"clusters":[91],"Cell-cycle":[96],"dataset":[97],"detailed":[100],"analysis":[101],"confirm":[102],"biological":[104],"nature":[105],"most":[108],"significant":[109],"clusters.":[110],"AVAILABILITY:":[111],"software":[113],"described":[114],"here":[115],"is":[116,125],"subpackage":[118],"part":[119],"ASTRONEURAL":[122],"package":[123],"available":[126,138],"upon":[127],"request":[128],"from":[129],"corresponding":[131],"author.":[132],"SUPPLEMENTARY":[133],"INFORMATION:":[134],"Supplementary":[135],"are":[137],"Bioinformatics":[140],"online.":[141]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}