{"id":"https://openalex.org/W2137563298","doi":"https://doi.org/10.1093/bioinformatics/bti706","title":"Discovering hidden viral piracy","display_name":"Discovering hidden viral piracy","publication_year":2005,"publication_date":"2005-10-06","ids":{"openalex":"https://openalex.org/W2137563298","doi":"https://doi.org/10.1093/bioinformatics/bti706","mag":"2137563298","pmid":"https://pubmed.ncbi.nlm.nih.gov/16210423"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bti706","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti706","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026267256","display_name":"Eddo Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]},{"id":"https://openalex.org/I1294667018","display_name":"Compugen (Israel)","ror":"https://ror.org/017vd4789","country_code":"IL","type":"company","lineage":["https://openalex.org/I1294667018"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Eddo Kim","raw_affiliation_strings":["Compugen Ltd Tel Aviv 69512, Israel","Compugen LtdTel Aviv 69512, Israel","Faculty of Life Sciences, Bar-Ilan UniversityRamat Gan 52900, Israel"],"affiliations":[{"raw_affiliation_string":"Compugen Ltd Tel Aviv 69512, Israel","institution_ids":[]},{"raw_affiliation_string":"Compugen LtdTel Aviv 69512, Israel","institution_ids":["https://openalex.org/I1294667018"]},{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan UniversityRamat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103193006","display_name":"Yossef Kliger","orcid":"https://orcid.org/0000-0002-2922-7896"},"institutions":[{"id":"https://openalex.org/I1294667018","display_name":"Compugen (Israel)","ror":"https://ror.org/017vd4789","country_code":"IL","type":"company","lineage":["https://openalex.org/I1294667018"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Yossef Kliger","raw_affiliation_strings":["Compugen LtdTel Aviv 69512, Israel"],"affiliations":[{"raw_affiliation_string":"Compugen LtdTel Aviv 69512, Israel","institution_ids":["https://openalex.org/I1294667018"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103193006"],"corresponding_institution_ids":["https://openalex.org/I1294667018"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.2461,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.55647785,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"21","issue":"23","first_page":"4216","last_page":"4222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homologous-chromosome","display_name":"Homologous chromosome","score":0.682212233543396},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6262426972389221},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5857212543487549},{"id":"https://openalex.org/keywords/protein-superfamily","display_name":"Protein superfamily","score":0.4927816689014435},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.4459463357925415},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.33439117670059204},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.32216620445251465},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3128259778022766}],"concepts":[{"id":"https://openalex.org/C64894306","wikidata":"https://www.wikidata.org/wiki/Q849622","display_name":"Homologous chromosome","level":3,"score":0.682212233543396},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6262426972389221},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5857212543487549},{"id":"https://openalex.org/C178180057","wikidata":"https://www.wikidata.org/wiki/Q7251477","display_name":"Protein superfamily","level":3,"score":0.4927816689014435},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.4459463357925415},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33439117670059204},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32216620445251465},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3128259778022766}],"mesh":[{"descriptor_ui":"D004266","descriptor_name":"DNA Virus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004266","descriptor_name":"DNA Virus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004266","descriptor_name":"DNA Virus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004267","descriptor_name":"DNA Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004267","descriptor_name":"DNA Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004267","descriptor_name":"DNA Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D012328","descriptor_name":"RNA Viruses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012328","descriptor_name":"RNA Viruses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012328","descriptor_name":"RNA Viruses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D021382","descriptor_name":"Protein Sorting Signals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021382","descriptor_name":"Protein Sorting Signals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021382","descriptor_name":"Protein Sorting Signals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/bti706","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti706","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16210423","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16210423","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1509178201","https://openalex.org/W1638089104","https://openalex.org/W1946706174","https://openalex.org/W1964145490","https://openalex.org/W1972084678","https://openalex.org/W1992918473","https://openalex.org/W1995294737","https://openalex.org/W1995924392","https://openalex.org/W2017101778","https://openalex.org/W2035881039","https://openalex.org/W2043771940","https://openalex.org/W2052002156","https://openalex.org/W2055043387","https://openalex.org/W2060546545","https://openalex.org/W2062296203","https://openalex.org/W2067312720","https://openalex.org/W2068665787","https://openalex.org/W2077294307","https://openalex.org/W2101220662","https://openalex.org/W2101771134","https://openalex.org/W2104286263","https://openalex.org/W2106882534","https://openalex.org/W2107436171","https://openalex.org/W2111965996","https://openalex.org/W2115668602","https://openalex.org/W2115954882","https://openalex.org/W2116099439","https://openalex.org/W2127203245","https://openalex.org/W2138387587","https://openalex.org/W2140965613","https://openalex.org/W2148853951","https://openalex.org/W2155469822","https://openalex.org/W2155519454","https://openalex.org/W2158842823","https://openalex.org/W2161746138","https://openalex.org/W2162792323","https://openalex.org/W2163352757","https://openalex.org/W2165270659","https://openalex.org/W2166712828","https://openalex.org/W2170938722","https://openalex.org/W2170974892"],"related_works":["https://openalex.org/W2002128513","https://openalex.org/W2092874662","https://openalex.org/W2108449047","https://openalex.org/W1968526004","https://openalex.org/W2136955853","https://openalex.org/W1579587268","https://openalex.org/W89925464","https://openalex.org/W2025168060","https://openalex.org/W1982527855","https://openalex.org/W2020392714"],"abstract_inverted_index":{"We":[0,41],"developed":[1],"a":[2,44,75],"method":[3,46],"to":[4,47],"assess":[5],"the":[6,49],"number":[7],"of":[8,51,64,71],"viral/human":[9,52],"homologs":[10,19,33],"and":[11,66,81],"discovered":[12],"that":[13,26],"at":[14],"least":[15],"917":[16],"highly":[17],"diverged":[18],"are":[20,27,34,82],"hidden":[21],"in":[22,78],"low-similarity":[23,32],"alignment":[24,39],"hits":[25],"usually":[28],"ignored.":[29],"However,":[30],"these":[31,72],"masked":[35],"by":[36],"many":[37],"false":[38],"hits.":[40],"therefore":[42,83],"applied":[43],"filtering":[45],"increase":[48],"proportion":[50],"homologous":[53,56],"proteins.":[54,68],"The":[55],"proteins":[57,73],"we":[58],"found":[59],"may":[60],"facilitate":[61],"functional":[62],"annotation":[63],"viral":[65],"human":[67],"Furthermore,":[69],"some":[70],"play":[74],"key":[76],"role":[77],"immune":[79],"modulation":[80],"therapeutic":[84],"protein":[85],"candidates.":[86]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}