{"id":"https://openalex.org/W2127341158","doi":"https://doi.org/10.1093/bioinformatics/bti700","title":"An attempt to define allergen-specific molecular surface features: a bioinformatic approach","display_name":"An attempt to define allergen-specific molecular surface features: a bioinformatic approach","publication_year":2005,"publication_date":"2005-10-04","ids":{"openalex":"https://openalex.org/W2127341158","doi":"https://doi.org/10.1093/bioinformatics/bti700","mag":"2127341158","pmid":"https://pubmed.ncbi.nlm.nih.gov/16204345"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bti700","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti700","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/23/4201/6138987/bti700.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/21/23/4201/6138987/bti700.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085568980","display_name":"R. Furmonaviciene","orcid":"https://orcid.org/0000-0003-1703-9684"},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Ruta Furmonaviciene","raw_affiliation_strings":["Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK","Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#"],"affiliations":[{"raw_affiliation_string":"Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK","institution_ids":[]},{"raw_affiliation_string":"Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002370634","display_name":"Brian J. Sutton","orcid":"https://orcid.org/0000-0002-4363-7568"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Brian J. Sutton","raw_affiliation_strings":["The Randall Division of Cell and Molecular Biophysics, King\u2019s College London, London, UK"],"affiliations":[{"raw_affiliation_string":"The Randall Division of Cell and Molecular Biophysics, King\u2019s College London, London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110446508","display_name":"Fabian Glaser","orcid":"https://orcid.org/0000-0003-4038-7185"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Fabian Glaser","raw_affiliation_strings":["European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK;"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK;","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064083972","display_name":"Charles A. Laughton","orcid":"https://orcid.org/0000-0003-4090-3960"},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Charlie A. Laughton","raw_affiliation_strings":["Molecular Recognition Group, School of Pharmacy, The University of Nottingham Nottingham, UK#TAB#"],"affiliations":[{"raw_affiliation_string":"Molecular Recognition Group, School of Pharmacy, The University of Nottingham Nottingham, UK#TAB#","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086511892","display_name":"Nick S. Jones","orcid":"https://orcid.org/0000-0002-4083-972X"},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nick Jones","raw_affiliation_strings":["Division of Otorhinolaryngology, School of Medical and Surgical Science, The University of Nottingham Nottingham, UK#TAB#"],"affiliations":[{"raw_affiliation_string":"Division of Otorhinolaryngology, School of Medical and Surgical Science, The University of Nottingham Nottingham, UK#TAB#","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108218067","display_name":"Herb F. Sewell","orcid":null},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Herb F. Sewell","raw_affiliation_strings":["Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#"],"affiliations":[{"raw_affiliation_string":"Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090775951","display_name":"Farouk Shakib","orcid":null},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Farouk Shakib","raw_affiliation_strings":["Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#"],"affiliations":[{"raw_affiliation_string":"Allergy Research Group, Institute of Infection, Immunity and Inflammation, The University of Nottingham Nottingham, UK#TAB#","institution_ids":["https://openalex.org/I142263535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5085568980"],"corresponding_institution_ids":["https://openalex.org/I142263535"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.2538,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.87649347,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"21","issue":"23","first_page":"4201","last_page":"4204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergen","display_name":"Allergen","score":0.7020967602729797},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5242928862571716},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5073539614677429},{"id":"https://openalex.org/keywords/surface-protein","display_name":"Surface protein","score":0.42805081605911255},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2760274112224579},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.17391124367713928},{"id":"https://openalex.org/keywords/allergy","display_name":"Allergy","score":0.16014450788497925},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.13368988037109375}],"concepts":[{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.7020967602729797},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5242928862571716},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5073539614677429},{"id":"https://openalex.org/C3019232848","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Surface protein","level":2,"score":0.42805081605911255},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2760274112224579},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17391124367713928},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.16014450788497925},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.13368988037109375}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003546","descriptor_name":"Cysteine Endopeptidases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003546","descriptor_name":"Cysteine Endopeptidases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003546","descriptor_name":"Cysteine Endopeptidases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003888","descriptor_name":"Desensitization, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051304","descriptor_name":"Profilins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051304","descriptor_name":"Profilins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051304","descriptor_name":"Profilins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/bti700","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti700","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/23/4201/6138987/bti700.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16204345","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16204345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:dora.dmu.ac.uk:2086/1230","is_oa":false,"landing_page_url":"http://hdl.handle.net/2086/1230","pdf_url":null,"source":{"id":"https://openalex.org/S4306400394","display_name":"DMU Open Research Archive (De Montfort University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66943878","host_organization_name":"De Montfort University","host_organization_lineage":["https://openalex.org/I66943878"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/5ccec2f8-5597-4587-adf2-5a78c6aaddd2","is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/5ccec2f8-5597-4587-adf2-5a78c6aaddd2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Furmonaviciene, R, Sutton, B J, Glaser, F, Laughton, C A, Jones, N, Sewell, H F & Shakib, F 2005, 'An attempt to define allergen-specific molecular surface features: a bioinformatic approach', BIOINFORMATICS, vol. 21, no. 23, pp. 4201 - 4204. https://doi.org/10.1093/bioinformatics/bti700","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bti700","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti700","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/23/4201/6138987/bti700.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6800000071525574,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320066","display_name":"Asthma and Lung UK","ror":"https://ror.org/03z7xev21"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2127341158.pdf","grobid_xml":"https://content.openalex.org/works/W2127341158.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1528476642","https://openalex.org/W1805406875","https://openalex.org/W1967434989","https://openalex.org/W1982351252","https://openalex.org/W1987688066","https://openalex.org/W2003144438","https://openalex.org/W2007230183","https://openalex.org/W2014385809","https://openalex.org/W2015317393","https://openalex.org/W2034660356","https://openalex.org/W2040703580","https://openalex.org/W2043345697","https://openalex.org/W2051662558","https://openalex.org/W2061833373","https://openalex.org/W2070344586","https://openalex.org/W2097706568","https://openalex.org/W2101363646","https://openalex.org/W2106882534","https://openalex.org/W2108819608","https://openalex.org/W2111876811","https://openalex.org/W2114737175","https://openalex.org/W2116099439","https://openalex.org/W2130479394","https://openalex.org/W2143776567","https://openalex.org/W2150444353","https://openalex.org/W2153544727","https://openalex.org/W2158714788","https://openalex.org/W2163352757","https://openalex.org/W2168518560","https://openalex.org/W6638355468","https://openalex.org/W6674647444"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1837502840"],"abstract_inverted_index":{"Allergens":[0],"are":[1,33,37],"proteins":[2,32],"that":[3,41,137],"elicit":[4],"T":[5],"helper":[6],"lymphocyte":[7],"type":[8],"2":[9],"(Th2)":[10],"responses":[11],"culminating":[12],"in":[13,92],"IgE":[14],"antibody":[15],"production":[16],"and":[17,111],"allergic":[18],"disease.":[19],"However,":[20],"we":[21],"have":[22,72,138],"no":[23],"answer":[24],"to":[25,58,78,87],"the":[26,44,67,75,93,120,149],"fundamental":[27],"question":[28],"of":[29,43,46,66,95,122,126,131,148],"why":[30],"certain":[31],"allergens,":[34],"while":[35],"others":[36],"not.":[38],"We":[39,71],"hypothesized":[40],"analysis":[42],"surface":[45],"diverse":[47],"allergens":[48],"may":[49,141],"reveal":[50],"common":[51],"structural":[52],"features":[53],"which":[54],"might":[55],"enable":[56],"them":[57],"be":[59],"recognized":[60],"as":[61],"Th2-inducing":[62],"antigens":[63],"by":[64,146],"cells":[65,147],"innate":[68,150],"immune":[69,151],"system.":[70,152],"therefore":[73],"used":[74],"ConSurf":[76],"server":[77],"search":[79],"for":[80],"allergen-specific":[81,123],"motifs.":[82],"This":[83],"has":[84],"enabled":[85],"us":[86],"identify":[88],"residue":[89],"conservation":[90],"patterns":[91,144],"homologues":[94],"Ara":[96],"t":[97],"8":[98],"(plant":[99,108],"profilin),":[100],"Act":[101],"c":[102],"1":[103,107],"(actinidin),":[104],"Bet":[105],"v":[106,113],"pathogenesis-related":[109],"protein)":[110],"Ves":[112],"5":[114],"(venom":[115],"allergen).":[116],"The":[117,135],"results":[118],"demonstrate":[119],"presence":[121],"patches":[124,136],"consisting":[125],"an":[127],"unusually":[128],"high":[129],"proportion":[130],"surface-exposed":[132],"hydrophobic":[133],"residues.":[134],"been":[139],"identified":[140],"represent":[142],"molecular":[143],"recognizable":[145]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}