{"id":"https://openalex.org/W2133098435","doi":"https://doi.org/10.1093/bioinformatics/bti517","title":"Computational cluster validation in post-genomic data analysis","display_name":"Computational cluster validation in post-genomic data analysis","publication_year":2005,"publication_date":"2005-05-25","ids":{"openalex":"https://openalex.org/W2133098435","doi":"https://doi.org/10.1093/bioinformatics/bti517","mag":"2133098435","pmid":"https://pubmed.ncbi.nlm.nih.gov/15914541"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bti517","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti517","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/15/3201/50340692/bioinformatics_21_15_3201.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/21/15/3201/50340692/bioinformatics_21_15_3201.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020541197","display_name":"Julia Handl","orcid":"https://orcid.org/0000-0002-4338-1806"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julia Handl","raw_affiliation_strings":["School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK. J.Handl@postgrad.manchester.ac.uk","School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK. J.Handl@postgrad.manchester.ac.uk","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102858903","display_name":"Joshua Knowles","orcid":"https://orcid.org/0000-0001-8112-6112"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Joshua Knowles","raw_affiliation_strings":["School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK","School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077370611","display_name":"Douglas B. Kell","orcid":"https://orcid.org/0000-0001-5838-7963"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Douglas B. Kell","raw_affiliation_strings":["School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK","School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, University of Manchester, Faraday Building, Sackville Street, PO Box 88, Manchester M60 1QD, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"School of Chemistry, University of Manchester Faraday Building, Sackville Street, PO Box 88,Manchester M60 1QD, UK#TAB#","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":15.6743,"has_fulltext":true,"cited_by_count":917,"citation_normalized_percentile":{"value":0.99544472,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"21","issue":"15","first_page":"3201","last_page":"3212"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.42100000381469727,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.42100000381469727,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10637","display_name":"Advanced Clustering Algorithms Research","score":0.2549999952316284,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11901","display_name":"Bayesian Methods and Mixture Models","score":0.08399999886751175,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.809360146522522},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7241294384002686},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.6284472346305847},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5395230054855347},{"id":"https://openalex.org/keywords/cluster","display_name":"Cluster (spacecraft)","score":0.44342976808547974},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.433480441570282},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.4309360384941101},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3624245226383209},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3169320225715637}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.809360146522522},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7241294384002686},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.6284472346305847},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5395230054855347},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.44342976808547974},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.433480441570282},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.4309360384941101},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3624245226383209},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3169320225715637},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/bti517","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti517","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/15/3201/50340692/bioinformatics_21_15_3201.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:15914541","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15914541","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/f623e470-8449-4950-ae70-39ffd308df60","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/f623e470-8449-4950-ae70-39ffd308df60","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handl, J, Knowles, J & Kell, D B 2005, 'Computational cluster validation in post-genomic data analysis', Bioinformatics, vol. 21, no. 15, pp. 3201-3212. https://doi.org/10.1093/bioinformatics/bti517","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.atira.dk:publications/f623e470-8449-4950-ae70-39ffd308df60","is_oa":false,"landing_page_url":"https://www.research.manchester.ac.uk/portal/en/publications/computational-cluster-validation-in-postgenomic-data-analysis(f623e470-8449-4950-ae70-39ffd308df60).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Handl, J, Knowles, J & Kell, D B 2005, 'Computational cluster validation in post-genomic data analysis', Bioinformatics, vol. 21, no. 15, pp. 3201-3212. https://doi.org/10.1093/bioinformatics/bti517","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bti517","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti517","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/15/3201/50340692/bioinformatics_21_15_3201.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Quality Education","id":"https://metadata.un.org/sdg/4","score":0.5199999809265137}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320334631","display_name":"Natural Environment Research Council","ror":"https://ror.org/02b5d8509"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2133098435.pdf","grobid_xml":"https://content.openalex.org/works/W2133098435.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W1519852910","https://openalex.org/W1521398555","https://openalex.org/W1531162979","https://openalex.org/W1554944419","https://openalex.org/W1556472699","https://openalex.org/W1559701175","https://openalex.org/W1651215666","https://openalex.org/W1673310716","https://openalex.org/W1679913846","https://openalex.org/W1708068686","https://openalex.org/W1774711529","https://openalex.org/W1788898868","https://openalex.org/W1965061252","https://openalex.org/W1969439320","https://openalex.org/W1987971958","https://openalex.org/W1992419399","https://openalex.org/W1992763738","https://openalex.org/W1995945562","https://openalex.org/W1996716987","https://openalex.org/W1999345637","https://openalex.org/W2008377040","https://openalex.org/W2018821242","https://openalex.org/W2026762972","https://openalex.org/W2029064186","https://openalex.org/W2033403400","https://openalex.org/W2042328724","https://openalex.org/W2051224630","https://openalex.org/W2052946386","https://openalex.org/W2053677366","https://openalex.org/W2054274648","https://openalex.org/W2063348290","https://openalex.org/W2071949631","https://openalex.org/W2081206009","https://openalex.org/W2090634555","https://openalex.org/W2102330962","https://openalex.org/W2104811588","https://openalex.org/W2109363337","https://openalex.org/W2109619915","https://openalex.org/W2116219421","https://openalex.org/W2117395768","https://openalex.org/W2117853077","https://openalex.org/W2121824548","https://openalex.org/W2127218421","https://openalex.org/W2129066856","https://openalex.org/W2131456395","https://openalex.org/W2135000328","https://openalex.org/W2135187880","https://openalex.org/W2135364554","https://openalex.org/W2137474062","https://openalex.org/W2137540340","https://openalex.org/W2137784044","https://openalex.org/W2143759264","https://openalex.org/W2144544802","https://openalex.org/W2146261447","https://openalex.org/W2146646206","https://openalex.org/W2150926065","https://openalex.org/W2151554142","https://openalex.org/W2154437541","https://openalex.org/W2157682389","https://openalex.org/W2157736844","https://openalex.org/W2160317546","https://openalex.org/W2160642098","https://openalex.org/W2161055009","https://openalex.org/W2162026804","https://openalex.org/W2168811230","https://openalex.org/W2171975443","https://openalex.org/W2302947639","https://openalex.org/W2496585406","https://openalex.org/W2612166593","https://openalex.org/W2767905780","https://openalex.org/W2797177778","https://openalex.org/W2799061466","https://openalex.org/W3106889297","https://openalex.org/W3138771162","https://openalex.org/W3140017782","https://openalex.org/W3203165331","https://openalex.org/W4235169531","https://openalex.org/W4245176872","https://openalex.org/W4247105055"],"related_works":["https://openalex.org/W2068608913","https://openalex.org/W3124914020","https://openalex.org/W2141033859","https://openalex.org/W2077542787","https://openalex.org/W2071701083","https://openalex.org/W2383687187","https://openalex.org/W2156434174","https://openalex.org/W2121496884","https://openalex.org/W2387910809","https://openalex.org/W2294221496"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1,64,177],"discovery":[2],"of":[3,12,19,39,51,118,136,142,170,173],"novel":[4,52],"biological":[5,81,159],"knowledge":[6],"from":[7],"the":[8,17,37,49,58,83,88,92,107,119,131,134,140,165,171,181,195],"ab":[9],"initio":[10],"analysis":[11],"post-genomic":[13,62,153],"data":[14,93,154],"relies":[15],"upon":[16],"use":[18],"unsupervised":[20],"processing":[21],"methods,":[22],"in":[23,30,43,91,106,122,180,194],"particular":[24,147],"clustering":[25,40,69,143],"techniques.":[26],"Much":[27],"recent":[28],"research":[29],"bioinformatics":[31],"has":[32],"therefore":[33],"been":[34,113],"focused":[35],"on":[36,48,149],"transfer":[38],"methods":[41],"introduced":[42],"other":[44],"scientific":[45],"fields":[46],"and":[47,77,157,167],"development":[50],"algorithms":[53],"specifically":[54],"designed":[55],"to":[56,87,129,152,163],"tackle":[57],"challenges":[59],"posed":[60],"by":[61,67],"data.":[63],"partitions":[65],"returned":[66],"a":[68,116,146],"algorithm":[70],"are":[71,104,161,192],"commonly":[72],"validated":[73],"using":[74],"visual":[75],"inspection":[76],"concordance":[78],"with":[79,133,145],"prior":[80],"knowledge--whether":[82],"clusters":[84],"actually":[85],"correspond":[86],"real":[89,158],"structure":[90],"is":[94,183,199],"somewhat":[95],"less":[96],"frequently":[97],"considered.":[98],"Suitable":[99],"computational":[100],"cluster":[101],"validation":[102,141],"techniques":[103,137],"available":[105,138,184,200],"general":[108],"data-mining":[109],"literature,":[110],"but":[111],"have":[112],"given":[114],"only":[115],"fraction":[117],"same":[120],"attention":[121],"bioinformatics.":[123],"RESULTS:":[124],"This":[125],"review":[126],"paper":[127],"aims":[128],"familiarize":[130],"reader":[132],"battery":[135],"for":[139],"results,":[144],"focus":[148],"their":[150],"application":[151],"analysis.":[155],"Synthetic":[156],"datasets":[160],"used":[162,179],"demonstrate":[164],"benefits,":[166],"also":[168],"some":[169],"perils,":[172],"analytical":[174],"clustervalidation.":[175],"AVAILABILITY:":[176],"software":[178],"experiments":[182],"at":[185,201],"http://dbkweb.ch.umist.ac.uk/handl/clustervalidation/.":[186,202],"SUPPLEMENTARY":[187],"INFORMATION:":[188],"Enlarged":[189],"colour":[190],"plots":[191],"provided":[193],"Supplementary":[196],"Material,":[197],"which":[198]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":44},{"year":2022,"cited_by_count":32},{"year":2021,"cited_by_count":60},{"year":2020,"cited_by_count":55},{"year":2019,"cited_by_count":39},{"year":2018,"cited_by_count":48},{"year":2017,"cited_by_count":48},{"year":2016,"cited_by_count":38},{"year":2015,"cited_by_count":49},{"year":2014,"cited_by_count":52},{"year":2013,"cited_by_count":58},{"year":2012,"cited_by_count":66}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}