{"id":"https://openalex.org/W2105432836","doi":"https://doi.org/10.1093/bioinformatics/bti188","title":"Multidimensional support vector machines for visualization of gene expression data","display_name":"Multidimensional support vector machines for visualization of gene expression data","publication_year":2004,"publication_date":"2004-12-17","ids":{"openalex":"https://openalex.org/W2105432836","doi":"https://doi.org/10.1093/bioinformatics/bti188","mag":"2105432836","pmid":"https://pubmed.ncbi.nlm.nih.gov/15608050"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bti188","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti188","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/4/439/48965084/bioinformatics_21_4_439.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/21/4/439/48965084/bioinformatics_21_4_439.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056846884","display_name":"Daisuke Komura","orcid":"https://orcid.org/0000-0002-0038-728X"},"institutions":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"D. Komura","raw_affiliation_strings":["Research Center for Advanced Science and Technology, University of Tokyo Tokyo 153-8904, Japan. komura@hal.rcast.u-tokyo.ac.jp","Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Advanced Science and Technology, University of Tokyo Tokyo 153-8904, Japan. komura@hal.rcast.u-tokyo.ac.jp","institution_ids":["https://openalex.org/I161296585"]},{"raw_affiliation_string":"Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090578339","display_name":"Hiroshi Nakamura","orcid":"https://orcid.org/0009-0005-6505-1903"},"institutions":[{"id":"https://openalex.org/I4210141749","display_name":"Center for High Pressure Science and Technology Advanced Research","ror":"https://ror.org/0389pw608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210141749","https://openalex.org/I4210143697"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"H. Nakamura","raw_affiliation_strings":["Research Center for Advanced Science and Technology and","Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Advanced Science and Technology and","institution_ids":["https://openalex.org/I4210141749"]},{"raw_affiliation_string":"Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074142176","display_name":"Seiichiro Tsutsumi","orcid":"https://orcid.org/0000-0002-9279-0657"},"institutions":[{"id":"https://openalex.org/I4210141749","display_name":"Center for High Pressure Science and Technology Advanced Research","ror":"https://ror.org/0389pw608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210141749","https://openalex.org/I4210143697"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"S. Tsutsumi","raw_affiliation_strings":["Research Center for Advanced Science and Technology and","Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Advanced Science and Technology and","institution_ids":["https://openalex.org/I4210141749"]},{"raw_affiliation_string":"Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001413231","display_name":"Hiroyuki Aburatani","orcid":"https://orcid.org/0000-0003-0438-1544"},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Aburatani","raw_affiliation_strings":["Genome Science Division, Center for Collaborative Research, University of Tokyo, Tokyo 153-8904, Japan","Genome Science Division, Center for Collaborative Research, University of Tokyo Tokyo 153-8904, Japan#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Science Division, Center for Collaborative Research, University of Tokyo, Tokyo 153-8904, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"Genome Science Division, Center for Collaborative Research, University of Tokyo Tokyo 153-8904, Japan#TAB#","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018093670","display_name":"Sozaburo Ihara","orcid":"https://orcid.org/0000-0001-8495-2073"},"institutions":[{"id":"https://openalex.org/I4210141749","display_name":"Center for High Pressure Science and Technology Advanced Research","ror":"https://ror.org/0389pw608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210141749","https://openalex.org/I4210143697"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"S. Ihara","raw_affiliation_strings":["Research Center for Advanced Science and Technology and","Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center for Advanced Science and Technology and","institution_ids":["https://openalex.org/I4210141749"]},{"raw_affiliation_string":"Research Center for Advanced Science and Technology University of Tokyo Tokyo 153\u20138904 Japan","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056846884"],"corresponding_institution_ids":["https://openalex.org/I161296585","https://openalex.org/I74801974"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.0357,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.86004721,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"21","issue":"4","first_page":"439","last_page":"444"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9466999769210815,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9466999769210815,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12303","display_name":"Tensor decomposition and applications","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2605","display_name":"Computational Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13748","display_name":"Advanced Statistical Modeling Techniques","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1705","display_name":"Computer Networks and Communications"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.7054504156112671},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6690815091133118},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.4981851577758789},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4462331235408783},{"id":"https://openalex.org/keywords/vector","display_name":"Vector (molecular biology)","score":0.439284086227417},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.43600988388061523},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.41261520981788635},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32451945543289185},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2628331780433655},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22982189059257507},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15342572331428528}],"concepts":[{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.7054504156112671},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6690815091133118},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.4981851577758789},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4462331235408783},{"id":"https://openalex.org/C92087593","wikidata":"https://www.wikidata.org/wiki/Q427389","display_name":"Vector (molecular biology)","level":4,"score":0.439284086227417},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.43600988388061523},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41261520981788635},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32451945543289185},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2628331780433655},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22982189059257507},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15342572331428528},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003205","descriptor_name":"Computing Methodologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003205","descriptor_name":"Computing Methodologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003205","descriptor_name":"Computing Methodologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/bti188","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti188","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/4/439/48965084/bioinformatics_21_4_439.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:15608050","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15608050","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bti188","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bti188","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/21/4/439/48965084/bioinformatics_21_4_439.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2105432836.pdf","grobid_xml":"https://content.openalex.org/works/W2105432836.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1563088657","https://openalex.org/W1727290854","https://openalex.org/W2059313996","https://openalex.org/W2097413644","https://openalex.org/W2102794349","https://openalex.org/W2108728387","https://openalex.org/W2109363337","https://openalex.org/W2138550913","https://openalex.org/W2140095548","https://openalex.org/W2143426320","https://openalex.org/W4250689175"],"related_works":["https://openalex.org/W2068608913","https://openalex.org/W2090763504","https://openalex.org/W3124914020","https://openalex.org/W2141033859","https://openalex.org/W2077542787","https://openalex.org/W2156434174","https://openalex.org/W2071701083","https://openalex.org/W2383687187","https://openalex.org/W148178222","https://openalex.org/W2121496884"],"abstract_inverted_index":{"MOTIVATION:":[0],"Since":[1],"DNA":[2],"microarray":[3],"experiments":[4],"provide":[5],"us":[6],"with":[7,18],"huge":[8],"amount":[9],"of":[10,25,45,55,58,96,128,137,154,163,177,182],"gene":[11,48,59,97,189],"expression":[12,49,60,98,190],"data,":[13,61,99],"they":[14],"should":[15],"be":[16,81,146],"analyzed":[17],"statistical":[19],"methods":[20,31],"to":[21,40,125,133,185],"extract":[22],"the":[23,43,53,76,84,129,138,142,175,186],"meanings":[24],"experimental":[26],"results.":[27],"Some":[28],"dimensionality":[29],"reduction":[30],"such":[32],"as":[33],"Principal":[34],"Component":[35],"Analysis":[36],"(PCA)":[37],"are":[38,157,166],"used":[39,87,147],"roughly":[41],"visualize":[42,134],"distribution":[44,136],"high":[46,118],"dimensional":[47,119,123],"data.":[50],"However,":[51],"in":[52,75,83,88,159],"case":[54],"binary":[56],"classification":[57,170],"PCA":[62],"does":[63],"not":[64,80],"utilize":[65],"class":[66,94,149,206],"information":[67],"when":[68],"choosing":[69],"axes.":[70,114],"Thus":[71],"clearly":[72,131],"separable":[73],"data":[74,120,130,139],"original":[77],"space":[78,86,124],"may":[79],"so":[82],"reduced":[85],"PCA.":[89],"RESULTS:":[90],"For":[91],"visualization":[92,204],"and":[93,132,168,201,205],"prediction":[95],"we":[100],"have":[101],"developed":[102],"a":[103,135],"new":[104],"SVM-based":[105],"method":[106,116,184],"called":[107],"multidimensional":[108],"SVMs,":[109],"that":[110,196],"generate":[111],"multiple":[112,143],"orthogonal":[113],"This":[115],"projects":[117],"into":[121],"lower":[122],"exhibit":[126],"properties":[127,153],"roughly.":[140],"Furthermore,":[141],"axes":[144],"can":[145],"for":[148,192,203],"prediction.":[150,207],"The":[151,180],"basic":[152],"conventional":[155],"SVMs":[156],"retained":[158],"our":[160,183,197],"method:":[161],"solutions":[162],"mathematical":[164],"programming":[165],"sparse,":[167],"nonlinear":[169],"is":[171,199],"implemented":[172],"implicitly":[173],"through":[174],"use":[176],"kernel":[178],"functions.":[179],"application":[181],"experimentally":[187],"obtained":[188],"datasets":[191],"patients'":[193],"samples":[194],"indicates":[195],"algorithm":[198],"efficient":[200],"useful":[202],"CONTACT:":[208],"komura@hal.rcast.u-tokyo.ac.jp.":[209]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-16T07:32:37.131356","created_date":"2025-10-10T00:00:00"}