{"id":"https://openalex.org/W2131239524","doi":"https://doi.org/10.1093/bioinformatics/bth065","title":"A metric model of amino acid substitution","display_name":"A metric model of amino acid substitution","publication_year":2004,"publication_date":"2004-02-10","ids":{"openalex":"https://openalex.org/W2131239524","doi":"https://doi.org/10.1093/bioinformatics/bth065","mag":"2131239524","pmid":"https://pubmed.ncbi.nlm.nih.gov/14871874"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bth065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bth065","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/20/8/1214/48905433/bioinformatics_20_8_1214.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/20/8/1214/48905433/bioinformatics_20_8_1214.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101883722","display_name":"Weijia Xu","orcid":"https://orcid.org/0000-0002-5134-6381"},"institutions":[{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Weijia Xu","raw_affiliation_strings":["Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA","Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA#TAB#","institution_ids":["https://openalex.org/I86519309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083499808","display_name":"Daniel P. Miranker","orcid":"https://orcid.org/0009-0003-8838-2890"},"institutions":[{"id":"https://openalex.org/I86519309","display_name":"The University of Texas at Austin","ror":"https://ror.org/00hj54h04","country_code":"US","type":"education","lineage":["https://openalex.org/I86519309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel P. Miranker","raw_affiliation_strings":["Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA","Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA","institution_ids":["https://openalex.org/I86519309"]},{"raw_affiliation_string":"Department of Computer Sciences, The Center for Computational Biology and Bioinformatics, University of Texas, Austin, TX 78712, USA#TAB#","institution_ids":["https://openalex.org/I86519309"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101883722"],"corresponding_institution_ids":["https://openalex.org/I86519309"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.2911,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.87904851,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"20","issue":"8","first_page":"1214","last_page":"1221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metric","display_name":"Metric (unit)","score":0.5397065877914429},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.531509280204773},{"id":"https://openalex.org/keywords/homology","display_name":"Homology (biology)","score":0.4754043519496918},{"id":"https://openalex.org/keywords/substitution","display_name":"Substitution (logic)","score":0.46327707171440125},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.45067504048347473},{"id":"https://openalex.org/keywords/sequence-alignment","display_name":"Sequence alignment","score":0.43428534269332886},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3750343322753906},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.355544775724411},{"id":"https://openalex.org/keywords/peptide-sequence","display_name":"Peptide sequence","score":0.21418938040733337},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19449254870414734},{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.18969997763633728},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1654445230960846}],"concepts":[{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.5397065877914429},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.531509280204773},{"id":"https://openalex.org/C165525559","wikidata":"https://www.wikidata.org/wiki/Q224180","display_name":"Homology (biology)","level":3,"score":0.4754043519496918},{"id":"https://openalex.org/C2778220771","wikidata":"https://www.wikidata.org/wiki/Q1522579","display_name":"Substitution (logic)","level":2,"score":0.46327707171440125},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.45067504048347473},{"id":"https://openalex.org/C45484198","wikidata":"https://www.wikidata.org/wiki/Q827246","display_name":"Sequence alignment","level":4,"score":0.43428534269332886},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3750343322753906},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.355544775724411},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.21418938040733337},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19449254870414734},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.18969997763633728},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1654445230960846},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/bth065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bth065","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/20/8/1214/48905433/bioinformatics_20_8_1214.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:14871874","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14871874","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.589.1323","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.589.1323","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/20/8/1214.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bth065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bth065","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/20/8/1214/48905433/bioinformatics_20_8_1214.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3684584078","display_name":"A Next Generation Biological Database Management System for Search Intensive Discovery in Genomics and Proteomics","funder_award_id":"0241180","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320308138","display_name":"Texas Higher Education Coordinating Board","ror":"https://ror.org/05as1qb59"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2131239524.pdf","grobid_xml":"https://content.openalex.org/works/W2131239524.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1491321484","https://openalex.org/W1496706542","https://openalex.org/W1525734744","https://openalex.org/W1554174647","https://openalex.org/W1555915743","https://openalex.org/W1659313070","https://openalex.org/W1967627390","https://openalex.org/W1977618577","https://openalex.org/W1990061958","https://openalex.org/W2013570924","https://openalex.org/W2022368654","https://openalex.org/W2027549089","https://openalex.org/W2038044292","https://openalex.org/W2051916497","https://openalex.org/W2055043387","https://openalex.org/W2072391778","https://openalex.org/W2074231493","https://openalex.org/W2084787613","https://openalex.org/W2087064593","https://openalex.org/W2087286364","https://openalex.org/W2092747888","https://openalex.org/W2115071473","https://openalex.org/W2120122292","https://openalex.org/W2133312664","https://openalex.org/W2135326109","https://openalex.org/W2136145671","https://openalex.org/W2143210482","https://openalex.org/W2143642163","https://openalex.org/W2165156013","https://openalex.org/W2292508834","https://openalex.org/W2601913882","https://openalex.org/W2725179571","https://openalex.org/W2799002609","https://openalex.org/W4236236547","https://openalex.org/W4243531027","https://openalex.org/W4255348633","https://openalex.org/W4293196852"],"related_works":["https://openalex.org/W2379444625","https://openalex.org/W2393147081","https://openalex.org/W2575869988","https://openalex.org/W4308647020","https://openalex.org/W2370088286","https://openalex.org/W2385568494","https://openalex.org/W2038132579","https://openalex.org/W2042068218","https://openalex.org/W4327590948","https://openalex.org/W2912058948"],"abstract_inverted_index":{"We":[0,34,58],"have":[1],"reworked":[2],"the":[3,6,14,36,39,60,63,85,92,101],"mathematics":[4],"of":[5,22,38,62,65,94,103],"point":[7],"accepted":[8,18],"mutation":[9],"model":[10,42],"(PAM)":[11],"by":[12,46],"calculating":[13,23],"expected":[15],"time":[16],"between":[17],"mutations":[19],"in":[20],"lieu":[21],"log-odds":[24],"probabilities.":[25],"The":[26,78],"resulting":[27],"substitution":[28],"matrix":[29],"(mPAM)":[30],"forms":[31],"a":[32,51],"metric.":[33],"validate":[35],"application":[37],"mPAM":[40,66,82],"evolutionary":[41],"for":[43],"sequence":[44,48,105],"homology":[45,55],"executing":[47],"queries":[49],"from":[50],"controlled":[52],"yeast":[53],"protein":[54,104],"search":[56],"benchmark.":[57],"compare":[59],"accuracy":[61],"results":[64],"and":[67,89],"PAM":[68],"similarity":[69],"matrices":[70],"as":[71,73],"well":[72],"three":[74,87],"prior":[75],"metric":[76],"models.":[77],"experiment":[79],"shows":[80],"that":[81],"significantly":[83],"outperforms":[84],"other":[86],"metrics":[88],"sufficiently":[90],"approaches":[91],"sensitivity":[93],"PAM250":[95],"to":[96,100],"make":[97],"it":[98],"applicable":[99],"management":[102],"databases.":[106]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}