{"id":"https://openalex.org/W2057053591","doi":"https://doi.org/10.1093/bioinformatics/btg1060","title":"Probabilistic models for identifying regulation networks","display_name":"Probabilistic models for identifying regulation networks","publication_year":2003,"publication_date":"2003-09-27","ids":{"openalex":"https://openalex.org/W2057053591","doi":"https://doi.org/10.1093/bioinformatics/btg1060","mag":"2057053591"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btg1060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btg1060","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/suppl_2/ii57/433991/btg1060.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"conference-abstract","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/19/suppl_2/ii57/433991/btg1060.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076999649","display_name":"Nir Friedman","orcid":"https://orcid.org/0000-0002-9678-3550"},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Nir Friedman","raw_affiliation_strings":["School of Computer Science & Engineering, Hebrew University, Ross Bldg, Room 203, Givat Ram, Jerusalem 91904, Israel","School of Computer Science and Engineering, Hebrew University, Ross Bldg, Room 203, Givat Ram, Jerusalem 91904, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science & Engineering, Hebrew University, Ross Bldg, Room 203, Givat Ram, Jerusalem 91904, Israel","institution_ids":["https://openalex.org/I197251160"]},{"raw_affiliation_string":"School of Computer Science and Engineering, Hebrew University, Ross Bldg, Room 203, Givat Ram, Jerusalem 91904, Israel","institution_ids":["https://openalex.org/I197251160"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5076999649"],"corresponding_institution_ids":["https://openalex.org/I197251160"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"suppl_2","first_page":"ii57","last_page":"ii57"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6075924634933472},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.598084568977356},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.5834022164344788},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.5681467056274414},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.4949137568473816},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.43494874238967896},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.417540043592453},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4112175405025482},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.40197068452835083},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.36535340547561646},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19568952918052673},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.11379513144493103}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6075924634933472},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.598084568977356},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5834022164344788},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.5681467056274414},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.4949137568473816},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.43494874238967896},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.417540043592453},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4112175405025482},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40197068452835083},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.36535340547561646},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19568952918052673},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11379513144493103},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/bioinformatics/btg1060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btg1060","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/suppl_2/ii57/433991/btg1060.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btg1060","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btg1060","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/suppl_2/ii57/433991/btg1060.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2494523064","https://openalex.org/W2943623134","https://openalex.org/W2215759665","https://openalex.org/W2960358116","https://openalex.org/W2030292806","https://openalex.org/W3041172967","https://openalex.org/W2749065928","https://openalex.org/W2147155098","https://openalex.org/W4287727129","https://openalex.org/W1734881440"],"abstract_inverted_index":{"Abstract":[0],"Microarray-based":[1],"hybridization":[2],"methods":[3,169],"techniques":[4],"allow":[5],"to":[6,50,63,136,144,172],"simultaneously":[7],"measure":[8],"the":[9,65,69,74,78,84,105,149,154,158,160,165,168,182,198],"expression":[10,86,107,229],"level":[11,108],"for":[12],"thousands":[13],"of":[14,24,33,58,68,76,94,109,142,157,200,208,214,220],"genes.":[15,202],"Such":[16],"measurements":[17],"contain":[18],"information":[19],"about":[20,83,197],"many":[21],"different":[22,212],"aspects":[23],"gene":[25,111,215,228],"regulation":[26],"and":[27,29,116,140,177,193,217,250],"function,":[28],"indeed":[30],"this":[31,56,96],"type":[32],"experiments":[34],"has":[35],"become":[36],"a":[37,99,113,121,206],"central":[38],"tool":[39],"in":[40,163],"biological":[41,53],"research.":[42],"A":[43],"major":[44],"computational":[45],"challenge":[46],"is":[47,62,98,232],"finding":[48],"ways":[49],"extract":[51],"new":[52,195],"understanding":[54,77],"from":[55,175],"wealth":[57],"data.":[59],"Our":[60],"goal":[61],"uncover":[64],"causal":[66],"structure":[67],"interactions":[70],"between":[71,124],"genes,":[72],"with":[73,235],"aim":[75],"regulatory":[79,118],"processes":[80],"that":[81,91,210],"bring":[82],"observed":[85],"patterns.":[87],"I":[88,130,151,203],"will":[89,131,152,204],"argue":[90],"one":[92],"way":[93],"addressing":[95],"question":[97],"Bayesian":[100,138],"framework,":[101],"where":[102],"we":[103,170,180],"treat":[104],"measured":[106],"each":[110,117],"as":[112,120],"random":[114],"variable":[115],"interaction":[119],"probabilistic":[122],"dependency":[123],"such":[125,146],"variables.":[126],"In":[127,148],"my":[128],"talk,":[129],"describe":[132],"an":[133,218],"ongoing":[134],"project":[135],"use":[137,171],"networks":[139],"extensions":[141],"them":[143],"model":[145],"dependencies.":[147],"talk":[150],"explain":[153],"basic":[155],"foundations":[156],"approach,":[159],"possible":[161],"choices":[162],"defining":[164],"modeling":[166],"language,":[167],"learn":[173],"models":[174,209],"data,":[176],"finally":[178],"how":[179],"interpret":[181],"learned":[183],"models.":[184],"This":[185,231],"latter":[186],"stage":[187],"includes":[188],"validation":[189],"against":[190],"known":[191],"biology,":[192],"constructing":[194],"hypotheses":[196],"role":[199],"unknown":[201],"present":[205],"progression":[207],"capture":[211],"aspect":[213],"regulation,":[216],"assessment":[219],"their":[221],"performance":[222],"on":[223],"several":[224],"large":[225],"scale":[226],"yeast":[227],"experiments.":[230],"joint":[233],"work":[234],"Dana":[236],"Pe\u2019er,":[237],"Iftach":[238],"Nachman,":[239],"Aviv":[240],"Regev,":[241],"Gal":[242],"Elidan,":[243],"Eran":[244],"Segel,":[245],"Micha":[246],"Shapira,":[247],"David":[248],"Botstein,":[249],"Daphne":[251],"Koller.":[252],"Contact:":[253],"nir@cs.huji.ac.il.":[254],"http://www.cs.huji.ac.il/~nir":[255]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}