{"id":"https://openalex.org/W2158691076","doi":"https://doi.org/10.1093/bioinformatics/btf860","title":"The Database of Quantitative Cellular Signaling:management and analysis of chemical kinetic models of signalingnetworks","display_name":"The Database of Quantitative Cellular Signaling:management and analysis of chemical kinetic models of signalingnetworks","publication_year":2003,"publication_date":"2003-02-12","ids":{"openalex":"https://openalex.org/W2158691076","doi":"https://doi.org/10.1093/bioinformatics/btf860","mag":"2158691076","pmid":"https://pubmed.ncbi.nlm.nih.gov/12584128"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btf860","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btf860","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/3/408/48903712/bioinformatics_19_3_408.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/19/3/408/48903712/bioinformatics_19_3_408.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055848943","display_name":"Sudhir Sivakumaran","orcid":"https://orcid.org/0000-0002-8586-0469"},"institutions":[{"id":"https://openalex.org/I194223965","display_name":"National Centre for Biological Sciences","ror":"https://ror.org/03gf8rp76","country_code":"IN","type":"facility","lineage":["https://openalex.org/I11947397","https://openalex.org/I194223965","https://openalex.org/I2799351866","https://openalex.org/I3149292468"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sudhir Sivakumaran","raw_affiliation_strings":["National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]},{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017809913","display_name":"Sridhar Hariharaputran","orcid":"https://orcid.org/0000-0002-9979-3244"},"institutions":[{"id":"https://openalex.org/I194223965","display_name":"National Centre for Biological Sciences","ror":"https://ror.org/03gf8rp76","country_code":"IN","type":"facility","lineage":["https://openalex.org/I11947397","https://openalex.org/I194223965","https://openalex.org/I2799351866","https://openalex.org/I3149292468"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sridhar Hariharaputran","raw_affiliation_strings":["National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]},{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055925753","display_name":"Jyoti Mishra","orcid":"https://orcid.org/0009-0002-9467-5481"},"institutions":[{"id":"https://openalex.org/I194223965","display_name":"National Centre for Biological Sciences","ror":"https://ror.org/03gf8rp76","country_code":"IN","type":"facility","lineage":["https://openalex.org/I11947397","https://openalex.org/I194223965","https://openalex.org/I2799351866","https://openalex.org/I3149292468"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jyoti Mishra","raw_affiliation_strings":["National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]},{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066858212","display_name":"Upinder S. Bhalla","orcid":"https://orcid.org/0000-0003-1722-5188"},"institutions":[{"id":"https://openalex.org/I194223965","display_name":"National Centre for Biological Sciences","ror":"https://ror.org/03gf8rp76","country_code":"IN","type":"facility","lineage":["https://openalex.org/I11947397","https://openalex.org/I194223965","https://openalex.org/I2799351866","https://openalex.org/I3149292468"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Upinder S. Bhalla","raw_affiliation_strings":["National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus, Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]},{"raw_affiliation_string":"National Centre for Biological Sciences, GKVK Campus,\n Bangalore 560065, India","institution_ids":["https://openalex.org/I194223965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.5827,"has_fulltext":false,"cited_by_count":126,"citation_normalized_percentile":{"value":0.95703175,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"19","issue":"3","first_page":"408","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.8141000270843506,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.8141000270843506,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.05389999970793724,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6161836981773376},{"id":"https://openalex.org/keywords/sbml","display_name":"SBML","score":0.48235076665878296},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.46325454115867615},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4551917612552643},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.4211732745170593},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3410775661468506},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33612996339797974},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.24795043468475342},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1822342872619629},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.1527954638004303},{"id":"https://openalex.org/keywords/markup-language","display_name":"Markup language","score":0.11777240037918091}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6161836981773376},{"id":"https://openalex.org/C87186988","wikidata":"https://www.wikidata.org/wiki/Q452197","display_name":"SBML","level":4,"score":0.48235076665878296},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.46325454115867615},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4551917612552643},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4211732745170593},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3410775661468506},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33612996339797974},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24795043468475342},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1822342872619629},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.1527954638004303},{"id":"https://openalex.org/C45874996","wikidata":"https://www.wikidata.org/wiki/Q37045","display_name":"Markup language","level":3,"score":0.11777240037918091},{"id":"https://openalex.org/C8797682","wikidata":"https://www.wikidata.org/wiki/Q2115","display_name":"XML","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000043","descriptor_name":"Abstracting and Indexing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000043","descriptor_name":"Abstracting and Indexing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000043","descriptor_name":"Abstracting and Indexing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btf860","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btf860","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/3/408/48903712/bioinformatics_19_3_408.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:12584128","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12584128","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.546.1868","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.546.1868","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://people.biology.ucsd.edu/jmishra/jmishra_bioinformatics2003.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.607.2476","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.607.2476","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/19/3/408.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btf860","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btf860","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/19/3/408/48903712/bioinformatics_19_3_408.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W74322794","https://openalex.org/W315268350","https://openalex.org/W1486453207","https://openalex.org/W1576664335","https://openalex.org/W1667514977","https://openalex.org/W1797216850","https://openalex.org/W1946177469","https://openalex.org/W1976548998","https://openalex.org/W1996662136","https://openalex.org/W1996965895","https://openalex.org/W2025089462","https://openalex.org/W2029108612","https://openalex.org/W2035551914","https://openalex.org/W2040890820","https://openalex.org/W2061417134","https://openalex.org/W2065546165","https://openalex.org/W2082528538","https://openalex.org/W2087361905","https://openalex.org/W2096337402","https://openalex.org/W2096652014","https://openalex.org/W2103129584","https://openalex.org/W2110694123","https://openalex.org/W2111644487","https://openalex.org/W2113950027","https://openalex.org/W2124236793","https://openalex.org/W2125713713","https://openalex.org/W2131067724","https://openalex.org/W2132582966","https://openalex.org/W2133667940","https://openalex.org/W2140000393","https://openalex.org/W2145118539","https://openalex.org/W2155418451","https://openalex.org/W2158716159","https://openalex.org/W2168655003","https://openalex.org/W2168761395","https://openalex.org/W2170652857","https://openalex.org/W2170825071"],"related_works":["https://openalex.org/W2150908245","https://openalex.org/W2211443823","https://openalex.org/W2097410126","https://openalex.org/W2136043941","https://openalex.org/W2043776573","https://openalex.org/W2735157934","https://openalex.org/W3080133182","https://openalex.org/W1869813392","https://openalex.org/W2026725606","https://openalex.org/W2020641517"],"abstract_inverted_index":{"MOTIVATION:":[0],"Analysis":[1],"of":[2,45,53,73,108,115,121,128,130,142,146,163],"cellular":[3],"signaling":[4,26,46,116,131,147,158,174],"interactions":[5],"is":[6,47,102,125,134,167,193],"expected":[7],"to":[8,48,137,150,172],"pose":[9],"an":[10],"enormous":[11],"informatics":[12],"challenge,":[13],"perhaps":[14],"even":[15],"larger":[16],"than":[17],"analyzing":[18],"the":[19,38,51,139,173,187,196],"genome.":[20],"The":[21,119,161,189],"complex":[22],"networks":[23],"arising":[24],"from":[25,185],"processes":[27],"are":[28,92,178,182],"traditionally":[29],"represented":[30],"as":[31],"block":[32],"diagrams.":[33],"A":[34],"key":[35],"step":[36],"in":[37,58,63,87,153],"evolution":[39],"toward":[40],"a":[41,59,71,126],"more":[42],"quantitative":[43,75],"understanding":[44],"explicitly":[49],"specify":[50],"kinetics":[52,110],"all":[54],"chemical":[55,109],"reaction":[56,112],"steps":[57],"pathway.":[60],"Technical":[61],"advances":[62],"proteomics":[64],"and":[65,81,90,111,149,181],"high-throughput":[66],"protein":[67],"interaction":[68],"assays":[69],"promise":[70],"flood":[72],"such":[74],"data.":[76],"While":[77],"annotations,":[78],"molecular":[79],"information":[80],"pathway":[82],"connectivity":[83],"have":[84],"been":[85],"compiled":[86],"several":[88,93],"databases,":[89],"there":[91,101],"proposals":[94],"for":[95,157],"general":[96],"cell":[97],"model":[98,175],"description":[99],"languages,":[100],"currently":[103],"little":[104],"experience":[105],"with":[106],"databases":[107],"level":[113,144],"models":[114,129],"networks.":[117],"RESULTS:":[118],"Database":[120,162],"Quantitative":[122,164],"Cellular":[123,165],"Signaling":[124,166],"repository":[127],"pathways.":[132],"It":[133],"intended":[135],"both":[136],"serve":[138],"growing":[140],"field":[141],"chemical-reaction":[143],"simulation":[145],"networks,":[148],"anticipate":[151],"issues":[152],"large-scale":[154],"data":[155],"management":[156],"chemistry.":[159],"AVAILABILITY:":[160],"available":[168,194],"at":[169,179],"http://doqcs.ncbs.res.in.":[170],"Links":[171],"simulator,":[176],"GENESIS/Kinetikit":[177],"http://www.ncbs.res.in/~bhalla/kkit/index.html":[180],"also":[183],"provided":[184],"within":[186],"database.":[188],"database":[190],"source":[191],"code":[192],"under":[195],"GNU":[197],"Public":[198],"License.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}