{"id":"https://openalex.org/W7125919216","doi":"https://doi.org/10.1093/bioinformatics/btag041","title":"DNAvi: integration, statistics, and visualization of cell-free DNA fragment traces","display_name":"DNAvi: integration, statistics, and visualization of cell-free DNA fragment traces","publication_year":2026,"publication_date":"2026-01-28","ids":{"openalex":"https://openalex.org/W7125919216","doi":"https://doi.org/10.1093/bioinformatics/btag041","pmid":"https://pubmed.ncbi.nlm.nih.gov/41609423"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btag041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag041","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bioinformatics/btag041","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071469198","display_name":"Anja Hess","orcid":"https://orcid.org/0000-0001-6634-9502"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Anja Hess","raw_affiliation_strings":["Department of Biology, Chemistry and Pharmacy, Freie Universit\u00e4t Berlin , 14195 Berlin,","Exploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charit\u00e9 Universit\u00e4tsmedizin Berlin , 10117 Berlin,","Max Planck Institute for Molecular Genetics , 14195 Berlin,"],"affiliations":[{"raw_affiliation_string":"Department of Biology, Chemistry and Pharmacy, Freie Universit\u00e4t Berlin , 14195 Berlin,","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Exploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charit\u00e9 Universit\u00e4tsmedizin Berlin , 10117 Berlin,","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Max Planck Institute for Molecular Genetics , 14195 Berlin,","institution_ids":["https://openalex.org/I4210142260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124147487","display_name":"Dominik Seelow","orcid":null},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dominik Seelow","raw_affiliation_strings":["Exploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charit\u00e9 Universit\u00e4tsmedizin Berlin , 10117 Berlin,","Institute of Medical Genetics and Human Genetics, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin , 13353 Berlin,"],"affiliations":[{"raw_affiliation_string":"Exploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charit\u00e9 Universit\u00e4tsmedizin Berlin , 10117 Berlin,","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Institute of Medical Genetics and Human Genetics, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin , 13353 Berlin,","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5124090391","display_name":"Helene Kretzmer","orcid":null},"institutions":[{"id":"https://openalex.org/I143288331","display_name":"Hasso Plattner Institute","ror":"https://ror.org/058rn5r42","country_code":"DE","type":"facility","lineage":["https://openalex.org/I143288331","https://openalex.org/I176453806"]},{"id":"https://openalex.org/I4210142260","display_name":"Max Planck Institute for Molecular Genetics","ror":"https://ror.org/03ate3e03","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210142260"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Helene Kretzmer","raw_affiliation_strings":["Hasso Plattner Institute for Digital Engineering, Digital Engineering Faculty, University of Potsdam , 14482 Potsdam,","Max Planck Institute for Molecular Genetics , 14195 Berlin,"],"affiliations":[{"raw_affiliation_string":"Hasso Plattner Institute for Digital Engineering, Digital Engineering Faculty, University of Potsdam , 14482 Potsdam,","institution_ids":["https://openalex.org/I143288331"]},{"raw_affiliation_string":"Max Planck Institute for Molecular Genetics , 14195 Berlin,","institution_ids":["https://openalex.org/I4210142260"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071469198"],"corresponding_institution_ids":["https://openalex.org/I4210139777","https://openalex.org/I4210142260","https://openalex.org/I75951250"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20491816,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.20020000636577606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.20020000636577606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.1851000040769577,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.05310000106692314,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.882099986076355},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.8046000003814697},{"id":"https://openalex.org/keywords/mit-license","display_name":"MIT License","score":0.7315999865531921},{"id":"https://openalex.org/keywords/fragment","display_name":"Fragment (logic)","score":0.6571000218391418},{"id":"https://openalex.org/keywords/license","display_name":"License","score":0.5776000022888184},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5034999847412109},{"id":"https://openalex.org/keywords/open-source","display_name":"Open source","score":0.4481000006198883}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.882099986076355},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.8046000003814697},{"id":"https://openalex.org/C174183944","wikidata":"https://www.wikidata.org/wiki/Q334661","display_name":"MIT License","level":3,"score":0.7315999865531921},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7143999934196472},{"id":"https://openalex.org/C2776235265","wikidata":"https://www.wikidata.org/wiki/Q18392052","display_name":"Fragment (logic)","level":2,"score":0.6571000218391418},{"id":"https://openalex.org/C2780560020","wikidata":"https://www.wikidata.org/wiki/Q79719","display_name":"License","level":2,"score":0.5776000022888184},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.5286999940872192},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.5109000205993652},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5034999847412109},{"id":"https://openalex.org/C3018397939","wikidata":"https://www.wikidata.org/wiki/Q3644502","display_name":"Open source","level":3,"score":0.4481000006198883},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.43639999628067017},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3986999988555908},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3984000086784363},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.3497999906539917},{"id":"https://openalex.org/C2988343187","wikidata":"https://www.wikidata.org/wiki/Q1130645","display_name":"Open source software","level":3,"score":0.32330000400543213},{"id":"https://openalex.org/C2781078984","wikidata":"https://www.wikidata.org/wiki/Q107205","display_name":"Mega-","level":2,"score":0.30000001192092896},{"id":"https://openalex.org/C2984968299","wikidata":"https://www.wikidata.org/wiki/Q1077784","display_name":"Software tool","level":3,"score":0.2881999909877777},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.27790001034736633},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.2703999876976013},{"id":"https://openalex.org/C64073096","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Interactive visualization","level":3,"score":0.262800008058548},{"id":"https://openalex.org/C4379982","wikidata":"https://www.wikidata.org/wiki/Q1273511","display_name":"Software visualization","level":5,"score":0.25839999318122864},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.2567000091075897},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.25}],"mesh":[{"descriptor_ui":"D000073888","descriptor_name":"Cell-Free Nucleic Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000073888","descriptor_name":"Cell-Free Nucleic Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000073888","descriptor_name":"Cell-Free Nucleic Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000073888","descriptor_name":"Cell-Free Nucleic Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btag041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag041","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41609423","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41609423","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:11711535","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12904835","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12904835","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12904835/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btag041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag041","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322434","display_name":"Max-Planck-Gesellschaft","ror":"https://ror.org/01hhn8329"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W2011301426","https://openalex.org/W2015159529","https://openalex.org/W2017146617","https://openalex.org/W2020883978","https://openalex.org/W2071535426","https://openalex.org/W2133059825","https://openalex.org/W2606089678","https://openalex.org/W2783674487","https://openalex.org/W2898391877","https://openalex.org/W2908462029","https://openalex.org/W2947989913","https://openalex.org/W2950266973","https://openalex.org/W3003257820","https://openalex.org/W3013146920","https://openalex.org/W3108402398","https://openalex.org/W3141884635","https://openalex.org/W3150635270","https://openalex.org/W3174187171","https://openalex.org/W4210486366","https://openalex.org/W4220957715","https://openalex.org/W4294993132","https://openalex.org/W4376279760","https://openalex.org/W4381435277","https://openalex.org/W4387381160","https://openalex.org/W4399353255","https://openalex.org/W4401494372","https://openalex.org/W4404787295","https://openalex.org/W4408743324","https://openalex.org/W4410077458","https://openalex.org/W4410618625","https://openalex.org/W4410785988","https://openalex.org/W4414559432"],"related_works":[],"abstract_inverted_index":{"DNAvi":[0],"is":[1,29],"implemented":[2],"in":[3],"Python":[4],"and":[5,24],"freely":[6],"available":[7,30],"on":[8],"GitHub":[9],"at":[10],"https://github.com/anjahess/DNAvi":[11],"under":[12,31],"a":[13],"GNU":[14],"General":[15],"Public":[16],"License":[17],"v3.0,":[18],"along":[19],"with":[20],"source":[21],"code,":[22],"documentation,":[23],"examples.":[25],"An":[26],"archived":[27],"version":[28],"https://doi.org/10.5281/zenodo.18401705.":[32]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2026-01-29T00:00:00"}