{"id":"https://openalex.org/W4413112143","doi":"https://doi.org/10.1093/bioinformatics/btaf441","title":"Hi-Enhancer: a two-stage framework for prediction and localization of enhancers based on Blending-KAN and Stacking-Auto models","display_name":"Hi-Enhancer: a two-stage framework for prediction and localization of enhancers based on Blending-KAN and Stacking-Auto models","publication_year":2025,"publication_date":"2025-08-11","ids":{"openalex":"https://openalex.org/W4413112143","doi":"https://doi.org/10.1093/bioinformatics/btaf441","pmid":"https://pubmed.ncbi.nlm.nih.gov/40796339"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaf441","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaf441","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bioinformatics/btaf441","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100382838","display_name":"Aimin Li","orcid":"https://orcid.org/0000-0002-6983-2310"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Aimin Li","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101874740","display_name":"Haotian Zhou","orcid":"https://orcid.org/0009-0008-1704-7354"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haotian Zhou","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102773066","display_name":"Rong Fei","orcid":"https://orcid.org/0000-0002-7092-4378"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rong Fei","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103712254","display_name":"Zou Juntao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115513","display_name":"Xi\u2019an University","ror":"https://ror.org/01zzmf129","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210115513"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juntao Zou","raw_affiliation_strings":["Department of Materials Science and Engineering, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Xi\u2019an University of Technology Department of Materials Science and Engineering, , Xi\u2019an, Shaanxi 710048,","Department of Materials Science and Engineering, Xi'an University of Technology, Xi'an, Shaanxi 710048, China"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210115513","https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Department of Materials Science and Engineering, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210115513","https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210115513","https://openalex.org/I4210131919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017698164","display_name":"Xiguo Yuan","orcid":"https://orcid.org/0000-0002-0822-5189"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiguo Yuan","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University , Xi\u2019an, Shaanxi 710071,","Xidian University School of Computer Science and Technology, , Xi\u2019an, Shaanxi 710071,","School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University , Xi\u2019an, Shaanxi 710071,","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"Xidian University School of Computer Science and Technology, , Xi\u2019an, Shaanxi 710071,","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100449874","display_name":"Yajun Liu","orcid":"https://orcid.org/0000-0002-5113-4709"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yajun Liu","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033317672","display_name":"Saurav Mallik","orcid":"https://orcid.org/0000-0003-4107-6784"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saurav Mallik","raw_affiliation_strings":["Department of Environmental Health, Harvard University T.H. Chan School of Public Health , Boston, MA 02115,","Department of Environmental Health, Harvard University T H Chan School of Public Health, Boston, MA 02115, United States","Harvard University T H Chan School of Public Health Department of Environmental Health, , Boston, MA 02115,"],"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Harvard University T.H. Chan School of Public Health , Boston, MA 02115,","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Environmental Health, Harvard University T H Chan School of Public Health, Boston, MA 02115, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Harvard University T H Chan School of Public Health Department of Environmental Health, , Boston, MA 02115,","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073391035","display_name":"Xinhong Hei","orcid":"https://orcid.org/0000-0002-6394-0492"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhong Hei","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100435780","display_name":"Lei Wang","orcid":"https://orcid.org/0000-0001-7502-1680"},"institutions":[{"id":"https://openalex.org/I4210104453","display_name":"Shaanxi Science and Technology Department","ror":"https://ror.org/01c2sx728","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210104453","https://openalex.org/I4210120069","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I4210131919","display_name":"Xi'an University of Technology","ror":"https://ror.org/038avdt50","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210131919"]},{"id":"https://openalex.org/I51622183","display_name":"Shaanxi University of Science and Technology","ror":"https://ror.org/034t3zs45","country_code":"CN","type":"education","lineage":["https://openalex.org/I51622183"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Wang","raw_affiliation_strings":["Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,"],"affiliations":[{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi\u2019an University of Technology , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]},{"raw_affiliation_string":"Shaanxi Key Laboratory for Network Computing and Security Technology, Xi'an University of Technology, Xi'an, Shaanxi 710048, China","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183"]},{"raw_affiliation_string":"Xi\u2019an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology, , Xi\u2019an, Shaanxi 710048,","institution_ids":["https://openalex.org/I4210131919","https://openalex.org/I51622183","https://openalex.org/I4210104453"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5100382838"],"corresponding_institution_ids":["https://openalex.org/I4210104453","https://openalex.org/I4210131919","https://openalex.org/I51622183"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23599199,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10860","display_name":"Speech and Audio Processing","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10860","display_name":"Speech and Audio Processing","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11447","display_name":"Blind Source Separation Techniques","score":0.920199990272522,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enhancer","display_name":"Enhancer","score":0.9058740139007568},{"id":"https://openalex.org/keywords/stacking","display_name":"Stacking","score":0.7791681289672852},{"id":"https://openalex.org/keywords/stage","display_name":"Stage (stratigraphy)","score":0.5670607089996338},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5488930940628052},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42578989267349243},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.33641302585601807},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22683078050613403},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.22354471683502197},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.13605409860610962},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07294216752052307}],"concepts":[{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.9058740139007568},{"id":"https://openalex.org/C33347731","wikidata":"https://www.wikidata.org/wiki/Q285210","display_name":"Stacking","level":2,"score":0.7791681289672852},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5670607089996338},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5488930940628052},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42578989267349243},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.33641302585601807},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22683078050613403},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.22354471683502197},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13605409860610962},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07294216752052307},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004742","descriptor_name":"Enhancer Elements, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaf441","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaf441","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:40796339","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40796339","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12758598","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12758598/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btaf441","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaf441","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G440191801","display_name":null,"funder_award_id":"62176146","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4919978494","display_name":null,"funder_award_id":"U2341271","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8962730789","display_name":null,"funder_award_id":"U2468206","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W28412257","https://openalex.org/W1807324513","https://openalex.org/W1998306196","https://openalex.org/W2018363492","https://openalex.org/W2095150428","https://openalex.org/W2171808845","https://openalex.org/W2247766769","https://openalex.org/W2565121836","https://openalex.org/W2807186140","https://openalex.org/W2808479265","https://openalex.org/W2914369697","https://openalex.org/W2915815599","https://openalex.org/W2963393302","https://openalex.org/W2970073459","https://openalex.org/W2996783813","https://openalex.org/W3013230828","https://openalex.org/W3096505797","https://openalex.org/W3105379318","https://openalex.org/W3129125493","https://openalex.org/W3134227030","https://openalex.org/W3138043598","https://openalex.org/W3139686558","https://openalex.org/W3178309952","https://openalex.org/W3189760294","https://openalex.org/W4213068753","https://openalex.org/W4229079441","https://openalex.org/W4303628999","https://openalex.org/W4308992137"],"related_works":["https://openalex.org/W2035329725","https://openalex.org/W2070875936","https://openalex.org/W2113330652","https://openalex.org/W4250391473","https://openalex.org/W4302292679","https://openalex.org/W4241625287","https://openalex.org/W2152841149","https://openalex.org/W2586783543","https://openalex.org/W4387598842","https://openalex.org/W2973036402"],"abstract_inverted_index":{"The":[0],"source":[1],"code":[2],"is":[3],"available":[4],"at":[5],"https://github.com/emanlee/Hi-Enhancer":[6],"and":[7],"https://doi.org/10.6084/m9.figshare.29262158.v1.":[8]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}