{"id":"https://openalex.org/W4404092049","doi":"https://doi.org/10.1093/bioinformatics/btae655","title":"InterLabelGO+: unraveling label correlations in protein function prediction","display_name":"InterLabelGO+: unraveling label correlations in protein function prediction","publication_year":2024,"publication_date":"2024-11-01","ids":{"openalex":"https://openalex.org/W4404092049","doi":"https://doi.org/10.1093/bioinformatics/btae655","pmid":"https://pubmed.ncbi.nlm.nih.gov/39499152"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae655","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae655","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae655/60428063/btae655.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae655/60428063/btae655.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014205734","display_name":"Quancheng Liu","orcid":"https://orcid.org/0000-0001-9552-1738"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quancheng Liu","raw_affiliation_strings":["Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101510848","display_name":"Chengxin Zhang","orcid":"https://orcid.org/0000-0001-7290-1324"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chengxin Zhang","raw_affiliation_strings":["Department of Biological Chemistry , University of Michigan , Ann Arbor, MI, 48109,","Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","Department of Biological Chemistry, University of Michigan, MI 48109-1085, United States","Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States"],"raw_orcid":"https://orcid.org/0000-0001-7290-1324","affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry , University of Michigan , Ann Arbor, MI, 48109,","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Biological Chemistry, University of Michigan, MI 48109-1085, United States","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031996829","display_name":"Lydia Freddolino","orcid":"https://orcid.org/0000-0002-5821-4226"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lydia Freddolino","raw_affiliation_strings":["Department of Biological Chemistry , University of Michigan , Ann Arbor, MI, 48109,","Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","Department of Biological Chemistry, University of Michigan, MI 48109-1085, United States","Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States"],"raw_orcid":"https://orcid.org/0000-0002-5821-4226","affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry , University of Michigan , Ann Arbor, MI, 48109,","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor, MI, 48109,","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Biological Chemistry, University of Michigan, MI 48109-1085, United States","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, MI 48109-2218, United States","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031996829","https://openalex.org/A5101510848"],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":1.4559,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.81899421,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"40","issue":"11","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.7480000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.07100000232458115,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.052299998700618744,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.8267982602119446},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8227678537368774},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.7195183634757996},{"id":"https://openalex.org/keywords/weighting","display_name":"Weighting","score":0.5433019995689392},{"id":"https://openalex.org/keywords/ranking","display_name":"Ranking (information retrieval)","score":0.5321490168571472},{"id":"https://openalex.org/keywords/protein-function-prediction","display_name":"Protein function prediction","score":0.529074490070343},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5268025398254395},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5212143659591675},{"id":"https://openalex.org/keywords/mit-license","display_name":"MIT License","score":0.4947201907634735},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.48069173097610474},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4780583679676056},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.47577252984046936},{"id":"https://openalex.org/keywords/dependency","display_name":"Dependency (UML)","score":0.44827035069465637},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.44020697474479675},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.43361276388168335},{"id":"https://openalex.org/keywords/protein-function","display_name":"Protein function","score":0.3827996253967285},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.19094640016555786}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.8267982602119446},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8227678537368774},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.7195183634757996},{"id":"https://openalex.org/C183115368","wikidata":"https://www.wikidata.org/wiki/Q856577","display_name":"Weighting","level":2,"score":0.5433019995689392},{"id":"https://openalex.org/C189430467","wikidata":"https://www.wikidata.org/wiki/Q7293293","display_name":"Ranking (information retrieval)","level":2,"score":0.5321490168571472},{"id":"https://openalex.org/C207060522","wikidata":"https://www.wikidata.org/wiki/Q7251473","display_name":"Protein function prediction","level":4,"score":0.529074490070343},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5268025398254395},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5212143659591675},{"id":"https://openalex.org/C174183944","wikidata":"https://www.wikidata.org/wiki/Q334661","display_name":"MIT License","level":3,"score":0.4947201907634735},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.48069173097610474},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4780583679676056},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.47577252984046936},{"id":"https://openalex.org/C19768560","wikidata":"https://www.wikidata.org/wiki/Q320727","display_name":"Dependency (UML)","level":2,"score":0.44827035069465637},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.44020697474479675},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.43361276388168335},{"id":"https://openalex.org/C2986374874","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Protein function","level":3,"score":0.3827996253967285},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.19094640016555786},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btae655","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae655","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae655/60428063/btae655.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39499152","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39499152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11568131","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11568131","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11568131/pdf/btae655.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae655","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae655","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae655/60428063/btae655.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/17"}],"awards":[{"id":"https://openalex.org/G1453181110","display_name":null,"funder_award_id":"#2138286","funder_id":"https://openalex.org/F4320337377","funder_display_name":"Office of Advanced Cyberinfrastructure"},{"id":"https://openalex.org/G1912064254","display_name":"Track 4:  Advanced CI Coordination Ecosystem: Monitoring and Measurement Services","funder_award_id":"2137603","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3562386289","display_name":null,"funder_award_id":"#2138296","funder_id":"https://openalex.org/F4320337377","funder_display_name":"Office of Advanced Cyberinfrastructure"},{"id":"https://openalex.org/G4010157413","display_name":null,"funder_award_id":"2138259","funder_id":"https://openalex.org/F4320337377","funder_display_name":"Office of Advanced Cyberinfrastructure"},{"id":"https://openalex.org/G4509968318","display_name":null,"funder_award_id":"R01 AI134678","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4676224565","display_name":"ACO: An Open CI Ecosystem to Advance Scientific Discovery (OpenCI)","funder_award_id":"2138296","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G509285653","display_name":"Track 3: COre National Ecosystem for CyberinfrasTructure (CONECT)","funder_award_id":"2138307","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5367127336","display_name":null,"funder_award_id":"#2138307","funder_id":"https://openalex.org/F4320337377","funder_display_name":"Office of Advanced Cyberinfrastructure"},{"id":"https://openalex.org/G5464919783","display_name":null,"funder_award_id":"2137603","funder_id":"https://openalex.org/F4320337377","funder_display_name":"Office of Advanced Cyberinfrastructure"},{"id":"https://openalex.org/G7063014021","display_name":null,"funder_award_id":"AI134678","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8300691027","display_name":"Track 2: Customized Multi-tier Assistance, Training, and Computational Help (MATCH) for End User ACCESS to CI","funder_award_id":"2138286","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8702286652","display_name":null,"funder_award_id":"AI134678","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337377","display_name":"Office of Advanced Cyberinfrastructure","ror":"https://ror.org/04nh1dc89"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404092049.pdf","grobid_xml":"https://content.openalex.org/works/W4404092049.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1974116356","https://openalex.org/W2098432760","https://openalex.org/W2100494857","https://openalex.org/W2103017472","https://openalex.org/W2108984616","https://openalex.org/W2119027485","https://openalex.org/W2167318540","https://openalex.org/W2611792444","https://openalex.org/W2615066396","https://openalex.org/W2807567459","https://openalex.org/W2911489562","https://openalex.org/W2989608901","https://openalex.org/W3137270128","https://openalex.org/W3143063265","https://openalex.org/W4236358448","https://openalex.org/W4312097792","https://openalex.org/W4360938460","https://openalex.org/W4366163632","https://openalex.org/W6849832982"],"related_works":["https://openalex.org/W2132241624","https://openalex.org/W4392173297","https://openalex.org/W4311683883","https://openalex.org/W4212902261","https://openalex.org/W4400311305","https://openalex.org/W4221030787","https://openalex.org/W2790811106","https://openalex.org/W4385413248","https://openalex.org/W2789551765","https://openalex.org/W3097598351"],"abstract_inverted_index":{"MOTIVATION:":[0],"Accurate":[1],"protein":[2,20,56,106],"function":[3,57,64,107],"prediction":[4,108],"is":[5,145,151,158],"crucial":[6],"for":[7,54,134],"understanding":[8],"biological":[9],"processes":[10],"and":[11,69,71,123,132,155,157,162],"advancing":[12],"biomedical":[13],"research.":[14],"However,":[15],"the":[16,24,31,79,92],"rapid":[17],"growth":[18],"of":[19,27,33,78,85,98],"sequences":[21],"far":[22],"outpaces":[23],"experimental":[25],"characterization":[26],"their":[28],"functions,":[29],"necessitating":[30],"development":[32],"automated":[34],"computational":[35],"methods.":[36],"RESULTS:":[37],"We":[38],"present":[39],"InterLabelGO+,":[40],"a":[41,46,61,88],"hybrid":[42],"approach":[43],"that":[44,65],"integrates":[45],"deep":[47],"learning-based":[48],"method":[49,53],"with":[50],"an":[51],"alignment-based":[52,80],"improved":[55],"prediction.":[58],"InterLabelGO+":[59,86,135],"incorporates":[60],"novel":[62],"loss":[63],"addresses":[66],"label":[67],"dependency":[68],"imbalance":[70],"further":[72],"enhances":[73],"performance":[74,90],"through":[75],"dynamic":[76],"weighting":[77],"component.":[81],"A":[82,143],"preliminary":[83],"version":[84],"achieved":[87],"strong":[89],"in":[91,153],"CAFA5":[93],"challenge,":[94],"ranking":[95],"sixth":[96],"out":[97],"1625":[99],"participating":[100],"teams.":[101],"Comprehensive":[102],"evaluations":[103],"on":[104,139,160],"large-scale":[105],"tasks":[109],"demonstrate":[110],"InterLabelGO+'s":[111],"ability":[112],"to":[113],"accurately":[114],"predict":[115],"Gene":[116],"Ontology":[117],"terms":[118],"across":[119],"various":[120],"functional":[121],"categories":[122],"evaluation":[124],"metrics.":[125],"AVAILABILITY":[126],"AND":[127],"IMPLEMENTATION:":[128],"The":[129,149],"source":[130],"code":[131],"datasets":[133],"are":[136],"freely":[137],"available":[138,146],"GitHub":[140],"at":[141,147],"https://github.com/QuanEvans/InterLabelGO.":[142],"web-server":[144],"https://seq2fun.dcmb.med.umich.edu/InterLabelGO/.":[148],"software":[150],"implemented":[152],"Python":[154],"PyTorch,":[156],"supported":[159],"Linux":[161],"macOS.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7}],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2025-10-10T00:00:00"}