{"id":"https://openalex.org/W4403785188","doi":"https://doi.org/10.1093/bioinformatics/btae639","title":"Causal relationships between diseases mined from the literature improve the use of polygenic risk scores","display_name":"Causal relationships between diseases mined from the literature improve the use of polygenic risk scores","publication_year":2024,"publication_date":"2024-10-26","ids":{"openalex":"https://openalex.org/W4403785188","doi":"https://doi.org/10.1093/bioinformatics/btae639","pmid":"https://pubmed.ncbi.nlm.nih.gov/39460944"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae639","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae639","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bioinformatics/btae639","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057787498","display_name":"Sumyyah Toonsi","orcid":"https://orcid.org/0000-0003-4746-4649"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Sumyyah Toonsi","raw_affiliation_strings":["Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,"],"affiliations":[{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090127959","display_name":"Iris Ivy Gauran","orcid":"https://orcid.org/0000-0002-7067-7012"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Iris Ivy Gauran","raw_affiliation_strings":["Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,"],"affiliations":[{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022587472","display_name":"Hernando Ombao","orcid":"https://orcid.org/0000-0001-7020-8091"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Hernando Ombao","raw_affiliation_strings":["Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,"],"affiliations":[{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059588755","display_name":"Paul N. Schofield","orcid":"https://orcid.org/0000-0002-5111-7263"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210096386","display_name":"Bridge University","ror":"https://ror.org/00cbm0437","country_code":"SS","type":"education","lineage":["https://openalex.org/I4210096386"]}],"countries":["GB","SS"],"is_corresponding":false,"raw_author_name":"Paul N Schofield","raw_affiliation_strings":["Department of Physiology, Development & Neuroscience, University of Cambridge , Cambridge CB2 3EG,","University of Cambridge Department of Physiology, Development & Neuroscience, , CB2 3EG,"],"affiliations":[{"raw_affiliation_string":"Department of Physiology, Development & Neuroscience, University of Cambridge , Cambridge CB2 3EG,","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210096386"]},{"raw_affiliation_string":"University of Cambridge Department of Physiology, Development & Neuroscience, , CB2 3EG,","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043808311","display_name":"Robert Hoehndorf","orcid":"https://orcid.org/0000-0001-8149-5890"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Robert Hoehndorf","raw_affiliation_strings":["Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","KAUST Center of Excellence for Generative AI, King Abdullah University of Science and Technology, Thuwal 23955 ,","KAUST Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology , Thuwal 23955,","SDAIA\u2013KAUST Center of Excellence in Data Science and Artificial Intelligence, King Abdullah University of Science and Technology , Thuwal 23955,","Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,","SDAIA\u2013KAUST Center of Excellence in Data Science and Artificial Intelligence, King Abdullah University of Science and Technology , Thuwal,","King Abdullah University of Science and Technology KAUST Center of Excellence for Smart Health (KCSH), , Thuwal,"],"affiliations":[{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"KAUST Center of Excellence for Generative AI, King Abdullah University of Science and Technology, Thuwal 23955 ,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"KAUST Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"SDAIA\u2013KAUST Center of Excellence in Data Science and Artificial Intelligence, King Abdullah University of Science and Technology , Thuwal 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"Computer, Electrical and Mathematical Sciences & Engineering, King Abdullah University of Science and Technology , Thuwal, 23955,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"SDAIA\u2013KAUST Center of Excellence in Data Science and Artificial Intelligence, King Abdullah University of Science and Technology , Thuwal,","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"King Abdullah University of Science and Technology KAUST Center of Excellence for Smart Health (KCSH), , Thuwal,","institution_ids":["https://openalex.org/I71920554"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5057787498"],"corresponding_institution_ids":["https://openalex.org/I71920554"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.7558,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.75031559,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"40","issue":"11","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.7634999752044678,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.7634999752044678,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.734000027179718,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.670799970626831,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"Polygenic risk score","score":0.6360831260681152},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5244348645210266},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.39458590745925903},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.35731828212738037},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.270385205745697},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2652240991592407},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24668502807617188},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13498646020889282},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.08152309060096741}],"concepts":[{"id":"https://openalex.org/C2993137441","wikidata":"https://www.wikidata.org/wiki/Q28135712","display_name":"Polygenic risk score","level":5,"score":0.6360831260681152},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5244348645210266},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39458590745925903},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.35731828212738037},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.270385205745697},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2652240991592407},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24668502807617188},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13498646020889282},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.08152309060096741},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096442","descriptor_name":"Genetic Risk Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020412","descriptor_name":"Multifactorial Inheritance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btae639","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae639","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39460944","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39460944","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11639291","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11639291","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11639291/pdf/btae639.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/376236","is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/376236","pdf_url":"https://www.repository.cam.ac.uk/bitstreams/fbdf1572-bdd0-4fe0-b3bf-69df35cc8b32/download","source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae639","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae639","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3154415231","display_name":null,"funder_award_id":"URF/1/4697-01-01","funder_id":"https://openalex.org/F4320322320","funder_display_name":"King Abdullah University of Science and Technology"},{"id":"https://openalex.org/G5380366079","display_name":null,"funder_award_id":"URF/1/5041-01-01","funder_id":"https://openalex.org/F4320322320","funder_display_name":"King Abdullah University of Science and Technology"},{"id":"https://openalex.org/G7444020395","display_name":null,"funder_award_id":"URF/1/4675-01-01","funder_id":"https://openalex.org/F4320322320","funder_display_name":"King Abdullah University of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320322320","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1097776622","https://openalex.org/W1507651605","https://openalex.org/W1698401562","https://openalex.org/W1996299724","https://openalex.org/W2006039263","https://openalex.org/W2008462328","https://openalex.org/W2065452687","https://openalex.org/W2082704080","https://openalex.org/W2090772115","https://openalex.org/W2119943416","https://openalex.org/W2143891888","https://openalex.org/W2152415104","https://openalex.org/W2159583324","https://openalex.org/W2162151166","https://openalex.org/W2513845892","https://openalex.org/W2516467211","https://openalex.org/W2616363959","https://openalex.org/W2770598799","https://openalex.org/W2886752110","https://openalex.org/W2899915536","https://openalex.org/W2958615822","https://openalex.org/W2969996045","https://openalex.org/W3015631361","https://openalex.org/W3064462073","https://openalex.org/W3083562835","https://openalex.org/W3121239749","https://openalex.org/W3134184401","https://openalex.org/W3169276191","https://openalex.org/W3171447052","https://openalex.org/W3214608846","https://openalex.org/W4200016620","https://openalex.org/W4210909814","https://openalex.org/W4211134725","https://openalex.org/W4211205882","https://openalex.org/W4212930729","https://openalex.org/W4224037213","https://openalex.org/W4240402692","https://openalex.org/W4281479961","https://openalex.org/W4285727181","https://openalex.org/W4308616307","https://openalex.org/W4362640647","https://openalex.org/W4377019533","https://openalex.org/W4388615775","https://openalex.org/W4391931369","https://openalex.org/W6634173072","https://openalex.org/W6637352914","https://openalex.org/W6649866123","https://openalex.org/W6808312555"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"The":[0],"data":[1],"are":[2],"available":[3],"through":[4],"https://github.com/bio-ontology-research-group/causal-relations-between-diseases.":[5]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}