{"id":"https://openalex.org/W4403480073","doi":"https://doi.org/10.1093/bioinformatics/btae625","title":"DPNN-ac4C: a dual-path neural network with self-attention mechanism for identification of N4-acetylcytidine (ac4C) in mRNA","display_name":"DPNN-ac4C: a dual-path neural network with self-attention mechanism for identification of N4-acetylcytidine (ac4C) in mRNA","publication_year":2024,"publication_date":"2024-10-17","ids":{"openalex":"https://openalex.org/W4403480073","doi":"https://doi.org/10.1093/bioinformatics/btae625","pmid":"https://pubmed.ncbi.nlm.nih.gov/39418179"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae625","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae625","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae625/59833529/btae625.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae625/59833529/btae625.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084323447","display_name":"Jiahao Yuan","orcid":"https://orcid.org/0000-0001-6530-3385"},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]},{"id":"https://openalex.org/I4210145393","display_name":"Hainan Agricultural School","ror":"https://ror.org/04p8ncq94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210145393"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiahao Yuan","raw_affiliation_strings":["School of Computer Science and Technology, Hainan University , Haikou 570228,","School of Computer Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University , Haikou 570228,","institution_ids":["https://openalex.org/I20942203","https://openalex.org/I4210145393"]},{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115596380","display_name":"Ziyi Wang","orcid":"https://orcid.org/0000-0002-9604-0335"},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]},{"id":"https://openalex.org/I4210145393","display_name":"Hainan Agricultural School","ror":"https://ror.org/04p8ncq94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210145393"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziyi Wang","raw_affiliation_strings":["School of Computer Science and Technology, Hainan University , Haikou 570228,","School of Computer Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University , Haikou 570228,","institution_ids":["https://openalex.org/I20942203","https://openalex.org/I4210145393"]},{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111352380","display_name":"Zhuoyu Pan","orcid":null},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuoyu Pan","raw_affiliation_strings":["International Business School, Hainan University , Haikou 570228,","International Business School, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Business School, Hainan University , Haikou 570228,","institution_ids":["https://openalex.org/I20942203"]},{"raw_affiliation_string":"International Business School, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062945616","display_name":"Aohan Li","orcid":"https://orcid.org/0000-0002-2385-3263"},"institutions":[{"id":"https://openalex.org/I20529979","display_name":"University of Electro-Communications","ror":"https://ror.org/02x73b849","country_code":"JP","type":"education","lineage":["https://openalex.org/I20529979"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Aohan Li","raw_affiliation_strings":["Graduate School of Informatics and Engineering, The University of Electro-Communications , Tokyo 182-8585,","Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Informatics and Engineering, The University of Electro-Communications , Tokyo 182-8585,","institution_ids":["https://openalex.org/I20529979"]},{"raw_affiliation_string":"Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, Japan","institution_ids":["https://openalex.org/I20529979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100353028","display_name":"Zilong Zhang","orcid":"https://orcid.org/0000-0002-4934-1258"},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]},{"id":"https://openalex.org/I4210145393","display_name":"Hainan Agricultural School","ror":"https://ror.org/04p8ncq94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210145393"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zilong Zhang","raw_affiliation_strings":["School of Computer Science and Technology, Hainan University , Haikou 570228,","School of Computer Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University , Haikou 570228,","institution_ids":["https://openalex.org/I20942203","https://openalex.org/I4210145393"]},{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061028143","display_name":"Feifei Cui","orcid":"https://orcid.org/0000-0001-7055-3813"},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]},{"id":"https://openalex.org/I4210145393","display_name":"Hainan Agricultural School","ror":"https://ror.org/04p8ncq94","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210145393"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Feifei Cui","raw_affiliation_strings":["School of Computer Science and Technology, Hainan University , Haikou 570228,","School of Computer Science and Technology, Hainan University, Haikou 570228, China"],"raw_orcid":"https://orcid.org/0000-0001-7055-3813","affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University , Haikou 570228,","institution_ids":["https://openalex.org/I20942203","https://openalex.org/I4210145393"]},{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University, Haikou 570228, China","institution_ids":["https://openalex.org/I20942203"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5061028143"],"corresponding_institution_ids":["https://openalex.org/I20942203","https://openalex.org/I4210145393"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":3.1654,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.92645606,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"40","issue":"11","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.916100025177002,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.916100025177002,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.054499998688697815,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.7455793619155884},{"id":"https://openalex.org/keywords/dual","display_name":"Dual (grammatical number)","score":0.7032651305198669},{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.6971167922019958},{"id":"https://openalex.org/keywords/path","display_name":"Path (computing)","score":0.6159818172454834},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.6020960807800293},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.5268586874008179},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.49772313237190247},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.46294865012168884},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.37945160269737244},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3284541368484497},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3271995782852173},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3144400119781494},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.26117247343063354},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09731972217559814},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09716075658798218},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.07468634843826294},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.07135552167892456}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.7455793619155884},{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.7032651305198669},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.6971167922019958},{"id":"https://openalex.org/C2777735758","wikidata":"https://www.wikidata.org/wiki/Q817765","display_name":"Path (computing)","level":2,"score":0.6159818172454834},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.6020960807800293},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5268586874008179},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.49772313237190247},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46294865012168884},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37945160269737244},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3284541368484497},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3271995782852173},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3144400119781494},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26117247343063354},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09731972217559814},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09716075658798218},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.07468634843826294},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.07135552167892456},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D003562","descriptor_name":"Cytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btae625","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae625","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae625/59833529/btae625.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39418179","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39418179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11549016","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11549016","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11549016/pdf/btae625.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae625","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae625","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae625/59833529/btae625.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2800956338","display_name":null,"funder_award_id":"62101100","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8875385470","display_name":null,"funder_award_id":"62262015","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323370","display_name":"Hainan University","ror":"https://ror.org/03q648j11"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403480073.pdf","grobid_xml":"https://content.openalex.org/works/W4403480073.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W2132247880","https://openalex.org/W2139166279","https://openalex.org/W2156125289","https://openalex.org/W2311607323","https://openalex.org/W2433743436","https://openalex.org/W2810819381","https://openalex.org/W2901932654","https://openalex.org/W2919115771","https://openalex.org/W2965635599","https://openalex.org/W2967960129","https://openalex.org/W3000260630","https://openalex.org/W3108267036","https://openalex.org/W3112131027","https://openalex.org/W3112172360","https://openalex.org/W3129096424","https://openalex.org/W3134504629","https://openalex.org/W3137227889","https://openalex.org/W3139265997","https://openalex.org/W3158703856","https://openalex.org/W3173360330","https://openalex.org/W3181752113","https://openalex.org/W3195747191","https://openalex.org/W4200547951","https://openalex.org/W4207028073","https://openalex.org/W4210499936","https://openalex.org/W4210810268","https://openalex.org/W4224737779","https://openalex.org/W4306404289","https://openalex.org/W4310675782","https://openalex.org/W4312827846","https://openalex.org/W4367672819","https://openalex.org/W4372342560","https://openalex.org/W4378528245","https://openalex.org/W4385245566","https://openalex.org/W4387499066","https://openalex.org/W4387701156","https://openalex.org/W4387798689","https://openalex.org/W4390955747","https://openalex.org/W4391618534","https://openalex.org/W4395110469","https://openalex.org/W4403782367","https://openalex.org/W6698064614","https://openalex.org/W6739901393"],"related_works":["https://openalex.org/W2382997850","https://openalex.org/W2390968135","https://openalex.org/W2382213751","https://openalex.org/W2351750670","https://openalex.org/W1597848696","https://openalex.org/W2354715126","https://openalex.org/W2388563748","https://openalex.org/W2375179084","https://openalex.org/W2366646518","https://openalex.org/W2370906336"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1,144],"modification":[2],"of":[3,39,46,66,91,105,108,111,115,136],"N4-acetylcytidine":[4],"(ac4C)":[5],"in":[6,18,49,69,138],"RNA":[7,92],"is":[8],"a":[9,15,55,60,133],"conserved":[10],"epigenetic":[11],"mark":[12],"that":[13,97],"plays":[14],"crucial":[16],"role":[17],"post-transcriptional":[19],"regulation,":[20],"mRNA":[21],"stability,":[22],"and":[23,34,82,88,113,147],"translation":[24],"efficiency.":[25],"Traditional":[26],"methods":[27],"for":[28,43,63],"detecting":[29],"ac4C":[30,47,67],"modifications":[31],"are":[32,149],"laborious":[33],"costly,":[35],"necessitating":[36],"the":[37,64,127],"development":[38],"efficient":[40],"computational":[41],"approaches":[42],"accurate":[44],"identification":[45,65],"sites":[48,68],"mRNA.":[50,70],"RESULTS:":[51],"We":[52],"present":[53],"DPNN-ac4C,":[54],"dual-path":[56],"neural":[57,80],"network":[58],"with":[59],"self-attention":[61,83],"mechanism":[62],"Our":[71],"model":[72,145],"integrates":[73],"embedding":[74],"modules,":[75],"bidirectional":[76],"GRU":[77],"networks,":[78,81],"convolutional":[79],"to":[84],"capture":[85],"both":[86],"local":[87],"global":[89],"features":[90],"sequences.":[93],"Extensive":[94],"evaluations":[95],"demonstrate":[96],"DPNN-ac4C":[98,123],"outperforms":[99],"existing":[100],"models,":[101],"achieving":[102],"an":[103,118],"AUROC":[104],"91.03%,":[106],"accuracy":[107,137],"82.78%,":[109],"MCC":[110],"65.78%,":[112],"specificity":[114],"84.78%":[116],"on":[117,152],"independent":[119],"test":[120],"set.":[121],"Moreover,":[122],"exhibits":[124],"robustness":[125],"under":[126],"Fast":[128],"Gradient":[129],"Method":[130],"attack,":[131],"maintaining":[132],"high":[134],"level":[135],"practical":[139],"applications.":[140],"AVAILABILITY":[141],"AND":[142],"IMPLEMENTATION:":[143],"code":[146],"dataset":[148],"publicly":[150],"available":[151],"GitHub":[153],"(https://github.com/shock1ng/DPNN-ac4C).":[154]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":10}],"updated_date":"2026-07-14T08:27:34.040176","created_date":"2025-10-10T00:00:00"}