{"id":"https://openalex.org/W4402131052","doi":"https://doi.org/10.1093/bioinformatics/btae533","title":"DTI-LM: language model powered drug\u2013target interaction prediction","display_name":"DTI-LM: language model powered drug\u2013target interaction prediction","publication_year":2024,"publication_date":"2024-09-01","ids":{"openalex":"https://openalex.org/W4402131052","doi":"https://doi.org/10.1093/bioinformatics/btae533","pmid":"https://pubmed.ncbi.nlm.nih.gov/39221997"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae533","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae533","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae533/58995571/btae533.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae533/58995571/btae533.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074491379","display_name":"Khandakar Tanvir Ahmed","orcid":null},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Khandakar Tanvir Ahmed","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816,","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States","Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009558194","display_name":"Md. Istiaq Ansari","orcid":"https://orcid.org/0000-0003-1520-1510"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Md Istiaq Ansari","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816,","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100441789","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0003-3605-9373"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Zhang","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816,","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States","Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816,","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, United States","institution_ids":["https://openalex.org/I106165777"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074491379"],"corresponding_institution_ids":["https://openalex.org/I106165777"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":12.7701,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.99092773,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"40","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.979200005531311,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6595066785812378},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.4585319757461548},{"id":"https://openalex.org/keywords/natural-language-processing","display_name":"Natural language processing","score":0.40388229489326477},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4001767039299011},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.2311617136001587}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6595066785812378},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4585319757461548},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.40388229489326477},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4001767039299011},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.2311617136001587}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btae533","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae533","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae533/58995571/btae533.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39221997","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39221997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11520403","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11520403","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11520403/pdf/btae533.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae533","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae533","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae533/58995571/btae533.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1157657881","display_name":null,"funder_award_id":"III2152030","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2676581382","display_name":null,"funder_award_id":"2246796","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2886067171","display_name":null,"funder_award_id":"NSF-III2152030","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G312611807","display_name":null,"funder_award_id":"2152030","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7379126765","display_name":null,"funder_award_id":"NSF-III2246796","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7580248291","display_name":null,"funder_award_id":"III2246796","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320310161","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4402131052.pdf"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W2018518196","https://openalex.org/W2096864392","https://openalex.org/W2102461176","https://openalex.org/W2127322768","https://openalex.org/W2153838454","https://openalex.org/W2583907533","https://openalex.org/W2592742128","https://openalex.org/W2753953057","https://openalex.org/W2781821160","https://openalex.org/W2785947426","https://openalex.org/W2952522777","https://openalex.org/W3005769002","https://openalex.org/W3007807538","https://openalex.org/W3009999522","https://openalex.org/W3018980093","https://openalex.org/W3028589594","https://openalex.org/W3039465695","https://openalex.org/W3158002239","https://openalex.org/W3177500196","https://openalex.org/W3177828909","https://openalex.org/W3186179742","https://openalex.org/W3194218357","https://openalex.org/W3213042299","https://openalex.org/W3217681006","https://openalex.org/W4205773061","https://openalex.org/W4206015450","https://openalex.org/W4206334877","https://openalex.org/W4281871249","https://openalex.org/W4283810898","https://openalex.org/W4286669150","https://openalex.org/W4292265045","https://openalex.org/W4307468223","https://openalex.org/W4309506674","https://openalex.org/W4313485929","https://openalex.org/W4323653169","https://openalex.org/W4327550249","https://openalex.org/W4387874094","https://openalex.org/W4390883205","https://openalex.org/W4400060970","https://openalex.org/W4403462031"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052","https://openalex.org/W3204019825"],"abstract_inverted_index":{"Source":[0],"code":[1],"is":[2],"available":[3],"at:":[4],"https://github.com/compbiolabucf/DTI-LM.":[5]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}