{"id":"https://openalex.org/W4396572253","doi":"https://doi.org/10.1093/bioinformatics/btae297","title":"Integrated convolution and self-attention for improving peptide toxicity prediction","display_name":"Integrated convolution and self-attention for improving peptide toxicity prediction","publication_year":2024,"publication_date":"2024-05-01","ids":{"openalex":"https://openalex.org/W4396572253","doi":"https://doi.org/10.1093/bioinformatics/btae297","pmid":"https://pubmed.ncbi.nlm.nih.gov/38696758"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae297","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae297","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae297/57390675/btae297.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae297/57390675/btae297.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026552847","display_name":"Shihu Jiao","orcid":"https://orcid.org/0000-0001-7428-4876"},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shihu Jiao","raw_affiliation_strings":["Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan"],"raw_orcid":"https://orcid.org/0000-0001-7428-4876","affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063256241","display_name":"Xiucai Ye","orcid":"https://orcid.org/0000-0002-5547-3919"},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Xiucai Ye","raw_affiliation_strings":["Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan"],"raw_orcid":"https://orcid.org/0000-0002-5547-3919","affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038336830","display_name":"Tetsuya Sakurai","orcid":"https://orcid.org/0000-0002-5789-7547"},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tetsuya Sakurai","raw_affiliation_strings":["Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba , Tsukuba 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017426085","display_name":"Quan Zou","orcid":"https://orcid.org/0000-0001-6406-1142"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210123686","display_name":"Quzhou University","ror":"https://ror.org/024nfx323","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210123686"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quan Zou","raw_affiliation_strings":["Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China , Chengdu 610054, China","Yangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China , Quzhou 324000, China","Yangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China, Quzhou, 324000, China","Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, 610054, China"],"raw_orcid":"https://orcid.org/0000-0001-6406-1142","affiliations":[{"raw_affiliation_string":"Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China , Chengdu 610054, China","institution_ids":["https://openalex.org/I150229711"]},{"raw_affiliation_string":"Yangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China , Quzhou 324000, China","institution_ids":["https://openalex.org/I4210123686","https://openalex.org/I150229711"]},{"raw_affiliation_string":"Yangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China, Quzhou, 324000, China","institution_ids":["https://openalex.org/I4210123686","https://openalex.org/I150229711"]},{"raw_affiliation_string":"Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, 610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101847722","display_name":"Ruijun Liu","orcid":"https://orcid.org/0000-0002-4877-0296"},"institutions":[{"id":"https://openalex.org/I82880672","display_name":"Beihang University","ror":"https://ror.org/00wk2mp56","country_code":"CN","type":"education","lineage":["https://openalex.org/I82880672"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ruijun Liu","raw_affiliation_strings":["School of Software, Beihang University , Beijing 100191, China","School of Software, Beihang University, Beijing, 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Software, Beihang University , Beijing 100191, China","institution_ids":["https://openalex.org/I82880672"]},{"raw_affiliation_string":"School of Software, Beihang University, Beijing, 100191, China","institution_ids":["https://openalex.org/I82880672"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063256241","https://openalex.org/A5101847722"],"corresponding_institution_ids":["https://openalex.org/I146399215","https://openalex.org/I82880672"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":5.2252,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.965103,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"40","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.6823999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.6823999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.1185000017285347,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.04560000076889992,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convolution","display_name":"Convolution (computer science)","score":0.73694908618927},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5886402130126953},{"id":"https://openalex.org/keywords/toxicity","display_name":"Toxicity","score":0.528569757938385},{"id":"https://openalex.org/keywords/peptide","display_name":"Peptide","score":0.503771960735321},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.35510697960853577},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.29549312591552734},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.23862332105636597},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.06421718001365662},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.06376802921295166}],"concepts":[{"id":"https://openalex.org/C45347329","wikidata":"https://www.wikidata.org/wiki/Q5166604","display_name":"Convolution (computer science)","level":3,"score":0.73694908618927},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5886402130126953},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.528569757938385},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.503771960735321},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35510697960853577},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.29549312591552734},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23862332105636597},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.06421718001365662},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06376802921295166}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btae297","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae297","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae297/57390675/btae297.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38696758","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38696758","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11654579","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11654579","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11654579/pdf/btae297.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:tsukuba.repo.nii.ac.jp:02010482","is_oa":true,"landing_page_url":"http://hdl.handle.net/2241/0002010482","pdf_url":"https://tsukuba.repo.nii.ac.jp/record/2010482/files/Bioinformatics_40-5-btae297.pdf","source":{"id":"https://openalex.org/S4306402076","display_name":"Terrestrial Environment Research Center (University of Tsukuba)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I146399215","host_organization_name":"University of Tsukuba","host_organization_lineage":["https://openalex.org/I146399215"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae297","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae297","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae297/57390675/btae297.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5400000214576721,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1293060989","display_name":null,"funder_award_id":"JPMJPF2017","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G1950104911","display_name":null,"funder_award_id":"JP23H03411","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7184098351","display_name":null,"funder_award_id":"JP22K12144","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8462935861","display_name":null,"funder_award_id":"62301368","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4396572253.pdf"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W2170747616","https://openalex.org/W2187089797","https://openalex.org/W2218204925","https://openalex.org/W2792923735","https://openalex.org/W2793390185","https://openalex.org/W2946321682","https://openalex.org/W2981285269","https://openalex.org/W2990887264","https://openalex.org/W3041538267","https://openalex.org/W3114113750","https://openalex.org/W3120960768","https://openalex.org/W3124828689","https://openalex.org/W3134163647","https://openalex.org/W3136918052","https://openalex.org/W3144701084","https://openalex.org/W3145990216","https://openalex.org/W3155214885","https://openalex.org/W3164264961","https://openalex.org/W3171087525","https://openalex.org/W3194954989","https://openalex.org/W3203741962","https://openalex.org/W4206722897","https://openalex.org/W4214608109","https://openalex.org/W4220912136","https://openalex.org/W4226068113","https://openalex.org/W4254689880","https://openalex.org/W4285678567","https://openalex.org/W4302018477","https://openalex.org/W4308370073","https://openalex.org/W4309185524","https://openalex.org/W4318480056","https://openalex.org/W4321003857","https://openalex.org/W4321015480","https://openalex.org/W4361218849","https://openalex.org/W4365459335","https://openalex.org/W4381432349","https://openalex.org/W4385252548","https://openalex.org/W4386386846","https://openalex.org/W4386439087","https://openalex.org/W4386852157","https://openalex.org/W4387640200","https://openalex.org/W4388080288","https://openalex.org/W4388621595","https://openalex.org/W4390946589"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"MOTIVATION:":[0],"Peptides":[1],"are":[2,50,177],"promising":[3],"agents":[4],"for":[5,46,65,84,202],"the":[6,20,29,55,78,98,106,170,190],"treatment":[7],"of":[8,11,22,32,80,100,108,124,140,175,192],"a":[9,36,91,120],"variety":[10],"diseases":[12],"due":[13],"to":[14,39,70,104],"their":[15,40,181],"specificity":[16],"and":[17,52,75,102,131,151,172,188],"efficacy.":[18],"However,":[19],"development":[21,56],"peptide-based":[23],"drugs":[24],"is":[25,61,204],"often":[26],"hindered":[27],"by":[28,161],"potential":[30],"toxicity":[31,49,73,110,144],"peptides,":[33,176],"which":[34,96],"poses":[35],"significant":[37],"barrier":[38],"clinical":[41],"application.":[42],"Traditional":[43],"experimental":[44],"methods":[45],"evaluating":[47],"peptide":[48,72,82,109,143,194],"time-consuming":[51],"costly,":[53],"making":[54],"process":[57],"inefficient.":[58],"Therefore,":[59],"there":[60],"an":[62],"urgent":[63],"need":[64],"computational":[66,93],"tools":[67],"specifically":[68],"designed":[69],"predict":[71],"accurately":[74],"rapidly,":[76],"facilitating":[77],"identification":[79],"safe":[81],"candidates":[83],"drug":[85],"development.":[86],"RESULTS:":[87],"We":[88],"provide":[89],"here":[90],"novel":[92],"approach,":[94],"CAPTP,":[95],"leverages":[97],"power":[99],"convolutional":[101],"self-attention":[103],"enhance":[105],"prediction":[107],"from":[111],"amino":[112],"acid":[113],"sequences.":[114],"CAPTP":[115,147,162,203],"demonstrates":[116],"outstanding":[117],"performance,":[118],"achieving":[119],"Matthews":[121],"correlation":[122],"coefficient":[123],"approximately":[125],"0.82":[126],"in":[127,169,179],"both":[128],"cross-validation":[129],"settings":[130],"on":[132],"independent":[133],"test":[134],"datasets.":[135],"This":[136,183],"performance":[137],"surpasses":[138],"that":[139,164],"existing":[141],"state-of-the-art":[142],"predictors.":[145],"Importantly,":[146],"maintains":[148],"its":[149],"robustness":[150],"generalizability":[152],"even":[153],"when":[154],"dealing":[155],"with":[156],"data":[157],"imbalances.":[158],"Further":[159],"analysis":[160],"reveals":[163],"certain":[165],"sequential":[166],"patterns,":[167],"particularly":[168],"head":[171],"central":[173],"regions":[174],"crucial":[178],"determining":[180],"toxicity.":[182],"insight":[184],"can":[185],"significantly":[186],"inform":[187],"guide":[189],"design":[191],"safer":[193],"drugs.":[195],"AVAILABILITY":[196],"AND":[197],"IMPLEMENTATION:":[198],"The":[199],"source":[200],"code":[201],"freely":[205],"available":[206],"at":[207],"https://github.com/jiaoshihu/CAPTP.":[208]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":3}],"updated_date":"2026-06-16T07:32:37.131356","created_date":"2025-10-10T00:00:00"}