{"id":"https://openalex.org/W4396561326","doi":"https://doi.org/10.1093/bioinformatics/btae294","title":"metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia","display_name":"metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia","publication_year":2024,"publication_date":"2024-04-29","ids":{"openalex":"https://openalex.org/W4396561326","doi":"https://doi.org/10.1093/bioinformatics/btae294","pmid":"https://pubmed.ncbi.nlm.nih.gov/38688567"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae294","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae294","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/40/5/btae294/57694361/btae294.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/40/5/btae294/57694361/btae294.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041603252","display_name":"Zulema Rodriguez-Hernandez","orcid":"https://orcid.org/0000-0003-0720-384X"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"funder","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["DE","ES"],"is_corresponding":false,"raw_author_name":"Zulema Rodriguez-Hernandez","raw_affiliation_strings":["Department of Biotechnology, Universitat Polit\u00e8cnica de Val\u00e8ncia , Valencia, 46022, Spain","Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany","Integrative Epidemiology Group, Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes , Madrid, 28029, Spain"],"raw_orcid":"https://orcid.org/0000-0003-0720-384X","affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Universitat Polit\u00e8cnica de Val\u00e8ncia , Valencia, 46022, Spain","institution_ids":["https://openalex.org/I60053951"]},{"raw_affiliation_string":"Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Integrative Epidemiology Group, Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes , Madrid, 28029, Spain","institution_ids":["https://openalex.org/I2801357902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103014356","display_name":"Mathias Gorski","orcid":"https://orcid.org/0000-0002-9103-5860"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mathias Gorski","raw_affiliation_strings":["Department of Genetic Epidemiology, University of Regensburg , Regensburg, 93053, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Epidemiology, University of Regensburg , Regensburg, 93053, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113404552","display_name":"Maria Tellez-Plaza","orcid":null},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"funder","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Maria Tellez-Plaza","raw_affiliation_strings":["Integrative Epidemiology Group, Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes , Madrid, 28029, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrative Epidemiology Group, Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes , Madrid, 28029, Spain","institution_ids":["https://openalex.org/I2801357902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043560883","display_name":"Pascal Schlosser","orcid":"https://orcid.org/0000-0002-8460-0462"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Pascal Schlosser","raw_affiliation_strings":["Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg , Freiburg, 79104, Germany","Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health , Baltimore, MD, 21287, USA","Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg , Freiburg, 79104, Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health , Baltimore, MD, 21287, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030007136","display_name":"Matthias Wuttke","orcid":"https://orcid.org/0000-0003-3420-5082"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Wuttke","raw_affiliation_strings":["Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center\u2014University of Freiburg , Freiburg, 79106, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.9367,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.77007394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"40","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8321999907493591,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8321999907493591,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.055799998342990875,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.023000000044703484,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.7874370813369751},{"id":"https://openalex.org/keywords/toolbox","display_name":"Toolbox","score":0.7844457626342773},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7675442099571228},{"id":"https://openalex.org/keywords/personalization","display_name":"Personalization","score":0.5304771065711975},{"id":"https://openalex.org/keywords/plug-in","display_name":"Plug-in","score":0.46759670972824097},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.4421636462211609},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4324891269207001},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.4249019920825958},{"id":"https://openalex.org/keywords/mit-license","display_name":"MIT License","score":0.41451412439346313},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.41229650378227234},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.3441799283027649},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.19437122344970703},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.16428273916244507},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.07502245903015137},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.07235127687454224}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.7874370813369751},{"id":"https://openalex.org/C2777655017","wikidata":"https://www.wikidata.org/wiki/Q1501161","display_name":"Toolbox","level":2,"score":0.7844457626342773},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7675442099571228},{"id":"https://openalex.org/C183003079","wikidata":"https://www.wikidata.org/wiki/Q1000371","display_name":"Personalization","level":2,"score":0.5304771065711975},{"id":"https://openalex.org/C4924752","wikidata":"https://www.wikidata.org/wiki/Q184148","display_name":"Plug-in","level":2,"score":0.46759670972824097},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4421636462211609},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4324891269207001},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4249019920825958},{"id":"https://openalex.org/C174183944","wikidata":"https://www.wikidata.org/wiki/Q334661","display_name":"MIT License","level":3,"score":0.41451412439346313},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.41229650378227234},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.3441799283027649},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.19437122344970703},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.16428273916244507},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07502245903015137},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.07235127687454224},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btae294","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae294","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/40/5/btae294/57694361/btae294.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38688567","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38688567","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11096268","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11096268","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11096268/pdf/btae294.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae294","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae294","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/40/5/btae294/57694361/btae294.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.46000000834465027}],"awards":[{"id":"https://openalex.org/G3023229226","display_name":"Proteomweite Assoziationsstudien zu Metaboliten und Nierenfunktion","funder_award_id":"523737608","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3785378965","display_name":null,"funder_award_id":"516564","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3820224712","display_name":null,"funder_award_id":"TRR 374","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3831163817","display_name":"SFB 1350: Tubulussystem und Interstitium der Niere: (Patho)Physiologie und Crosstalk","funder_award_id":"387509280","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4024340028","display_name":"SFB 1453: Nephrogenetik (NephGen)","funder_award_id":"431984000","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4168357507","display_name":null,"funder_award_id":"R01 EY RES 511967","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4935269520","display_name":"EXC 2189: CIBSS  Centre for Integrative Biological Signalling Studies","funder_award_id":"390939984","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G534687194","display_name":"TRR 374: Tubulussystem und Interstitium der Niere: (Patho)Physiologie und Crosstalk","funder_award_id":"509149993","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G655555550","display_name":null,"funder_award_id":"Project-ID 390939984","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7936941248","display_name":null,"funder_award_id":"CIBSS-EXC-2189","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7942449511","display_name":null,"funder_award_id":"EXC-2189","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8104757639","display_name":"Kausale Inferenz durch maschinelles Lernen: Nutzung multidimensionaler omicsDaten f\u00fcr ein besseres Verst\u00e4ndnis komplexer Krankheiten","funder_award_id":"530592017","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8288036582","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8468884293","display_name":null,"funder_award_id":"SFB 1453","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8855989013","display_name":null,"funder_award_id":"SFB 1350","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4396561326.pdf","grobid_xml":"https://content.openalex.org/works/W4396561326.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W2099085143","https://openalex.org/W2133520037","https://openalex.org/W2944540884","https://openalex.org/W2947278243","https://openalex.org/W2956245605","https://openalex.org/W2977833465","https://openalex.org/W3001645436","https://openalex.org/W3118524636","https://openalex.org/W3162800482","https://openalex.org/W4200137222","https://openalex.org/W4200324792","https://openalex.org/W4200409077","https://openalex.org/W4304698823"],"related_works":["https://openalex.org/W4205140848","https://openalex.org/W2068663075","https://openalex.org/W2978678743","https://openalex.org/W2797837731","https://openalex.org/W4393677513","https://openalex.org/W47352601","https://openalex.org/W2013194361","https://openalex.org/W2562353568","https://openalex.org/W189850294","https://openalex.org/W4320855360"],"abstract_inverted_index":{"SUMMARY:":[0],"This":[1],"article":[2],"introduces":[3],"the":[4,21,70,94,122],"metaGWASmanager,":[5],"which":[6],"streamlines":[7],"genome-wide":[8],"association":[9,41,58,99],"studies":[10,28],"within":[11],"large-scale":[12],"meta-analysis":[13],"consortia.":[14],"It":[15],"is":[16],"a":[17,52,108],"toolbox":[18,50,63],"for":[19,55,114],"both":[20,69],"central":[22],"consortium":[23],"analysis":[24,86],"group":[25],"and":[26,43,72,92,96],"participating":[27,79],"to":[29],"generate":[30],"homogeneous":[31],"phenotypes,":[32],"minimize":[33],"unwanted":[34],"variability":[35],"from":[36],"inconsistent":[37],"methodologies,":[38],"ensure":[39],"high-quality":[40],"results,":[42,100],"implement":[44],"time-efficient":[45],"quality":[46],"control":[47],"workflows.":[48],"The":[49,61],"features":[51],"plug-in-based":[53],"approach":[54],"customization":[56,116],"of":[57,78,98],"testing.":[59],"RESULTS:":[60],"metaGWASmanager":[62],"has":[64],"been":[65],"successfully":[66],"deployed":[67],"in":[68,84],"CKDGen":[71],"MetalGWAS":[73],"Initiative":[74],"consortia":[75],"across":[76],"hundreds":[77],"studies,":[80],"demonstrating":[81],"its":[82],"effectiveness":[83],"GWAS":[85],"optimization":[87],"by":[88],"automating":[89],"routine":[90],"tasks":[91],"ensuring":[93],"value":[95],"reliability":[97],"thus,":[101],"ultimately":[102],"promoting":[103],"scientific":[104],"discovery.":[105],"We":[106],"provide":[107],"simulated":[109],"data":[110],"set":[111],"with":[112],"examples":[113],"script":[115],"so":[117],"that":[118],"readers":[119],"can":[120],"reproduce":[121],"pipeline":[123],"at":[124],"their":[125],"convenience.":[126],"AVAILABILITY":[127],"AND":[128],"IMPLEMENTATION:":[129],"GitHub:":[130],"https://github.com/genepi-freiburg/metaGWASmanager.":[131]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-22T08:00:12.763002","created_date":"2025-10-10T00:00:00"}