{"id":"https://openalex.org/W4394867130","doi":"https://doi.org/10.1093/bioinformatics/btae267","title":"Topological benchmarking of algorithms to infer gene regulatory networks from single-cell RNA-seq data","display_name":"Topological benchmarking of algorithms to infer gene regulatory networks from single-cell RNA-seq data","publication_year":2024,"publication_date":"2024-04-16","ids":{"openalex":"https://openalex.org/W4394867130","doi":"https://doi.org/10.1093/bioinformatics/btae267","pmid":"https://pubmed.ncbi.nlm.nih.gov/38627250"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae267","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae267","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bioinformatics/btae267","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008614848","display_name":"Marco Stock","orcid":"https://orcid.org/0000-0001-9485-1217"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Marco Stock","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","TUM School of Life Sciences Weihenstephan, Technical University of Munich , Munich 85354, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"TUM School of Life Sciences Weihenstephan, Technical University of Munich , Munich 85354, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049676668","display_name":"Niclas Popp","orcid":null},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Niclas Popp","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047553056","display_name":"Jonathan Fiorentino","orcid":"https://orcid.org/0000-0003-2096-3210"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jonathan Fiorentino","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077404140","display_name":"Antonio Scialdone","orcid":"https://orcid.org/0000-0002-4956-2843"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Antonio Scialdone","raw_affiliation_strings":["Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Computational Biology, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Epigenetics and Stem Cells, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 81377, Germany","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"Institute of Functional Epigenetics, Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health , Munich 85764, Germany","institution_ids":["https://openalex.org/I3018134672"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008614848"],"corresponding_institution_ids":["https://openalex.org/I3018134672","https://openalex.org/I62916508"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":2.044,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.8638285,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"40","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9871000051498413,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.9021425247192383},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7535495758056641},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.6940973997116089},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6775029897689819},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.593210756778717},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.584374725818634},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5840452909469604},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.49428749084472656},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.22721073031425476},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.17760586738586426},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11618480086326599},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.09406810998916626}],"concepts":[{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.9021425247192383},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7535495758056641},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6940973997116089},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6775029897689819},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.593210756778717},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.584374725818634},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5840452909469604},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.49428749084472656},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.22721073031425476},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17760586738586426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11618480086326599},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.09406810998916626},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092386","descriptor_name":"Single-Cell Gene Expression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019985","descriptor_name":"Benchmarking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btae267","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae267","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38627250","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38627250","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11096270","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11096270","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11096270/pdf/btae267.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:push-zb.helmholtz-munich.de:70543","is_oa":true,"landing_page_url":"https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=70543","pdf_url":"https://push-zb.helmholtz-munich.de/deliver.php?id=39999","source":{"id":"https://openalex.org/S7407055352","display_name":"PuSH - Publication Server of Helmholtz Zentrum M\u00fcnchen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics 40:btae267 (2024)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae267","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae267","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17","score":0.5199999809265137}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320876","display_name":"Helmholtz-Gemeinschaft","ror":"https://ror.org/0281dp749"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W118100147","https://openalex.org/W1967934074","https://openalex.org/W1971937094","https://openalex.org/W1974444469","https://openalex.org/W1989921625","https://openalex.org/W1998153799","https://openalex.org/W2015077700","https://openalex.org/W2023649587","https://openalex.org/W2025828346","https://openalex.org/W2033078279","https://openalex.org/W2033193852","https://openalex.org/W2033289379","https://openalex.org/W2043469923","https://openalex.org/W2045313237","https://openalex.org/W2056944867","https://openalex.org/W2060464767","https://openalex.org/W2070722739","https://openalex.org/W2111384508","https://openalex.org/W2112090702","https://openalex.org/W2112609377","https://openalex.org/W2112868720","https://openalex.org/W2117495845","https://openalex.org/W2123402141","https://openalex.org/W2132022337","https://openalex.org/W2134423940","https://openalex.org/W2136965966","https://openalex.org/W2139997707","https://openalex.org/W2140258573","https://openalex.org/W2143086681","https://openalex.org/W2163480486","https://openalex.org/W2165247488","https://openalex.org/W2171111703","https://openalex.org/W2214256683","https://openalex.org/W2332016763","https://openalex.org/W2467468633","https://openalex.org/W2520902279","https://openalex.org/W2757234574","https://openalex.org/W2784007581","https://openalex.org/W2795624730","https://openalex.org/W2797716674","https://openalex.org/W2800502420","https://openalex.org/W2808743742","https://openalex.org/W2827166133","https://openalex.org/W2901292166","https://openalex.org/W2913785384","https://openalex.org/W2918079314","https://openalex.org/W2949321019","https://openalex.org/W2951850020","https://openalex.org/W2963884852","https://openalex.org/W2997323475","https://openalex.org/W2997831639","https://openalex.org/W2998742848","https://openalex.org/W3003422837","https://openalex.org/W3102858608","https://openalex.org/W3103967557","https://openalex.org/W3109243443","https://openalex.org/W3120850525","https://openalex.org/W3127647799","https://openalex.org/W3139392374","https://openalex.org/W3159699835","https://openalex.org/W3170261942","https://openalex.org/W4200384935","https://openalex.org/W4212837655","https://openalex.org/W4225537122","https://openalex.org/W4292508558","https://openalex.org/W4312512934","https://openalex.org/W4315435709","https://openalex.org/W4321604841","https://openalex.org/W4322502360","https://openalex.org/W4378838672","https://openalex.org/W4391920714","https://openalex.org/W4396895461","https://openalex.org/W6702046917","https://openalex.org/W6849539507","https://openalex.org/W6855148359"],"related_works":["https://openalex.org/W4238897586","https://openalex.org/W435179959","https://openalex.org/W2619091065","https://openalex.org/W2059640416","https://openalex.org/W2950199998","https://openalex.org/W2560421304","https://openalex.org/W2951387065","https://openalex.org/W2134575910","https://openalex.org/W4385727351","https://openalex.org/W4306798985"],"abstract_inverted_index":{"STREAMLINE":[0],"is":[1],"available":[2,12],"at":[3,13],"https://github.com/ScialdoneLab/STREAMLINE.":[4],"The":[5],"data":[6],"generated":[7],"in":[8],"this":[9],"study":[10],"are":[11],"https://doi.org/10.5281/zenodo.10710444.":[14]},"counts_by_year":[{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":1}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}