{"id":"https://openalex.org/W4386410831","doi":"https://doi.org/10.1093/bioinformatics/btad534","title":"Machine learning-based quantification for disease uncertainty increases the statistical power of genetic association studies","display_name":"Machine learning-based quantification for disease uncertainty increases the statistical power of genetic association studies","publication_year":2023,"publication_date":"2023-09-01","ids":{"openalex":"https://openalex.org/W4386410831","doi":"https://doi.org/10.1093/bioinformatics/btad534","pmid":"https://pubmed.ncbi.nlm.nih.gov/37665736"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btad534","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad534","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad534/51344501/btad534.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad534/51344501/btad534.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100397354","display_name":"Jun Young Park","orcid":"https://orcid.org/0000-0002-9098-2858"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I152238500","display_name":"Chosun University","ror":"https://ror.org/01zt9a375","country_code":"KR","type":"education","lineage":["https://openalex.org/I152238500"]},{"id":"https://openalex.org/I4210114610","display_name":"Phyzen (South Korea)","ror":"https://ror.org/020xg4k98","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210114610"]},{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["KR","US"],"is_corresponding":true,"raw_author_name":"Jun Young Park","raw_affiliation_strings":["Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","Neurozen Inc. , Seoul 06168, Korea","Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea","Neurozen Inc., Seoul, 06160, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Neurozen Inc. , Seoul 06168, Korea","institution_ids":["https://openalex.org/I4210164563"]},{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Neurozen Inc., Seoul, 06160, Korea","institution_ids":["https://openalex.org/I4210114610"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027731408","display_name":"Jang Jae Lee","orcid":"https://orcid.org/0000-0001-8787-9940"},"institutions":[{"id":"https://openalex.org/I152238500","display_name":"Chosun University","ror":"https://ror.org/01zt9a375","country_code":"KR","type":"education","lineage":["https://openalex.org/I152238500"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jang Jae Lee","raw_affiliation_strings":["Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea"],"affiliations":[{"raw_affiliation_string":"Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea","institution_ids":["https://openalex.org/I152238500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009851933","display_name":"Younghwa Lee","orcid":"https://orcid.org/0000-0002-5312-212X"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Younghwa Lee","raw_affiliation_strings":["Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101748622","display_name":"Dongsoo Lee","orcid":"https://orcid.org/0000-0002-7057-745X"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dongsoo Lee","raw_affiliation_strings":["Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025069678","display_name":"Jungsoo Gim","orcid":"https://orcid.org/0000-0002-6454-9751"},"institutions":[{"id":"https://openalex.org/I152238500","display_name":"Chosun University","ror":"https://ror.org/01zt9a375","country_code":"KR","type":"education","lineage":["https://openalex.org/I152238500"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jungsoo Gim","raw_affiliation_strings":["Department of Biomedical Science, Chosun University , Gwangju 61452, Korea","Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","Department of Biomedical Science, Chosun University, Gwangju, 61452, Korea","Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Science, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Department of Biomedical Science, Chosun University, Gwangju, 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea","institution_ids":["https://openalex.org/I152238500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038477961","display_name":"Lindsay A. Farrer","orcid":"https://orcid.org/0000-0001-5533-4225"},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lindsay Farrer","raw_affiliation_strings":["Departments of Epidemiology and Biostatistics, Boston University School of Public Health , Boston, MA 02118, United States","Departments of Medicine (Biomedical Genetics), Neurology, and Ophthalmology, Boston University Chobanian & Avedisian School of Medicine , Boston, MA 02118, United States"],"affiliations":[{"raw_affiliation_string":"Departments of Epidemiology and Biostatistics, Boston University School of Public Health , Boston, MA 02118, United States","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Departments of Medicine (Biomedical Genetics), Neurology, and Ophthalmology, Boston University Chobanian & Avedisian School of Medicine , Boston, MA 02118, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026944704","display_name":"Kun Ho Lee","orcid":"https://orcid.org/0000-0003-4144-8162"},"institutions":[{"id":"https://openalex.org/I152238500","display_name":"Chosun University","ror":"https://ror.org/01zt9a375","country_code":"KR","type":"education","lineage":["https://openalex.org/I152238500"]},{"id":"https://openalex.org/I4210114610","display_name":"Phyzen (South Korea)","ror":"https://ror.org/020xg4k98","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210114610"]},{"id":"https://openalex.org/I4210155455","display_name":"Korea Brain Research Institute","ror":"https://ror.org/055zd7d59","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210155455"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kun Ho Lee","raw_affiliation_strings":["Department of Biomedical Science, Chosun University , Gwangju 61452, Korea","Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","Korea Brain Research Institute , Daegu 41068, Korea","Department of Biomedical Science, Chosun University, Gwangju, 61452, Korea","Neurozen Inc., Seoul, 06160, Korea","Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea","Korea Brain Research Institute, Daegu, 41068, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Science, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Gwangju Alzheimer\u2019s & Related Dementia Cohort Research Center, Chosun University , Gwangju 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Korea Brain Research Institute , Daegu 41068, Korea","institution_ids":["https://openalex.org/I4210155455"]},{"raw_affiliation_string":"Department of Biomedical Science, Chosun University, Gwangju, 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Neurozen Inc., Seoul, 06160, Korea","institution_ids":["https://openalex.org/I4210114610"]},{"raw_affiliation_string":"Gwangju Alzheimer's & Related Dementia Cohort Research Center, Chosun University, Gwangju, 61452, Korea","institution_ids":["https://openalex.org/I152238500"]},{"raw_affiliation_string":"Korea Brain Research Institute, Daegu, 41068, Korea","institution_ids":["https://openalex.org/I4210155455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087186763","display_name":"Sungho Won","orcid":"https://orcid.org/0000-0001-5751-5089"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I4210090949","display_name":"Korea Environment Institute","ror":"https://ror.org/00bxeqa64","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210090949","https://openalex.org/I4210097958"]},{"id":"https://openalex.org/I4210135449","display_name":"NCSOFT (South Korea)","ror":"https://ror.org/03q4mza74","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210135449"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sungho Won","raw_affiliation_strings":["Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","Institute of Health and Environment, Seoul National University , Seoul 08826, Korea","Interdisciplinary Program in Bioinformatics, Seoul National University , Seoul 08826, Korea","RexSoft Inc , Seoul 08826, Korea","Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, 08826, Korea","RexSoft Inc, Seoul, 08826, Korea","Institute of Health and Environment, Seoul National University, Seoul, 08826, Korea","Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea"],"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Institute of Health and Environment, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I4210090949"]},{"raw_affiliation_string":"Interdisciplinary Program in Bioinformatics, Seoul National University , Seoul 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"RexSoft Inc , Seoul 08826, Korea","institution_ids":["https://openalex.org/I4210135449"]},{"raw_affiliation_string":"Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"RexSoft Inc, Seoul, 08826, Korea","institution_ids":[]},{"raw_affiliation_string":"Institute of Health and Environment, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5100397354"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I152238500","https://openalex.org/I4210114610","https://openalex.org/I4210164563"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.6279,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.7692807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"39","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9914000034332275,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.8197867274284363},{"id":"https://openalex.org/keywords/statistical-power","display_name":"Statistical power","score":0.6360538005828857},{"id":"https://openalex.org/keywords/weighting","display_name":"Weighting","score":0.6056824326515198},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.5983715653419495},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.586073637008667},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5763053894042969},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.5277560353279114},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.45825517177581787},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4328967034816742},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.41846761107444763},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33397504687309265},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.21888765692710876},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21651408076286316},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.21365150809288025},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20623084902763367},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19197359681129456},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16165146231651306},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.13266363739967346}],"concepts":[{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.8197867274284363},{"id":"https://openalex.org/C96608239","wikidata":"https://www.wikidata.org/wiki/Q1199823","display_name":"Statistical power","level":2,"score":0.6360538005828857},{"id":"https://openalex.org/C183115368","wikidata":"https://www.wikidata.org/wiki/Q856577","display_name":"Weighting","level":2,"score":0.6056824326515198},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5983715653419495},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.586073637008667},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5763053894042969},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.5277560353279114},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.45825517177581787},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4328967034816742},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.41846761107444763},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33397504687309265},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.21888765692710876},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21651408076286316},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.21365150809288025},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20623084902763367},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19197359681129456},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16165146231651306},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.13266363739967346},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btad534","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad534","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad534/51344501/btad534.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37665736","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37665736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10539075","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10539075","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10539075/pdf/btad534.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btad534","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad534","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad534/51344501/btad534.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7799999713897705,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G1510316451","display_name":null,"funder_award_id":"2021R1A5","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G2213427975","display_name":null,"funder_award_id":"23-BR-03-05","funder_id":"https://openalex.org/F4320318413","funder_display_name":"Korea Brain Research Institute"},{"id":"https://openalex.org/G3034753964","display_name":null,"funder_award_id":"grant","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G3898419974","display_name":null,"funder_award_id":"1711120216","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4600871193","display_name":null,"funder_award_id":"2021R1A5A1033157","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G5711340399","display_name":null,"funder_award_id":"NRF-2021R1A5A1033157","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G7826783983","display_name":null,"funder_award_id":"23-BR-03-05","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G7942505582","display_name":null,"funder_award_id":"22-BR-03-05","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G8260466032","display_name":null,"funder_award_id":"22-BR-03-05","funder_id":"https://openalex.org/F4320318413","funder_display_name":"Korea Brain Research Institute"},{"id":"https://openalex.org/G848733465","display_name":null,"funder_award_id":"NRF-2021R1A5A1033157","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"}],"funders":[{"id":"https://openalex.org/F4320318413","display_name":"Korea Brain Research Institute","ror":"https://ror.org/055zd7d59"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322065","display_name":"National IT Industry Promotion Agency","ror":"https://ror.org/026v53e29"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386410831.pdf"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W902069429","https://openalex.org/W1583837637","https://openalex.org/W1959895361","https://openalex.org/W1988971925","https://openalex.org/W2003958717","https://openalex.org/W2023168194","https://openalex.org/W2046378189","https://openalex.org/W2054961347","https://openalex.org/W2058358730","https://openalex.org/W2066491797","https://openalex.org/W2072837173","https://openalex.org/W2082347868","https://openalex.org/W2082992035","https://openalex.org/W2101234009","https://openalex.org/W2111525324","https://openalex.org/W2113708991","https://openalex.org/W2131570638","https://openalex.org/W2140054173","https://openalex.org/W2149569695","https://openalex.org/W2155152361","https://openalex.org/W2161633633","https://openalex.org/W2163013660","https://openalex.org/W2166336042","https://openalex.org/W2181523240","https://openalex.org/W2189115178","https://openalex.org/W2275694984","https://openalex.org/W2416189753","https://openalex.org/W2905035821","https://openalex.org/W2908002252","https://openalex.org/W2916749909","https://openalex.org/W2964750218","https://openalex.org/W2995875704","https://openalex.org/W3088019192","https://openalex.org/W3092894050","https://openalex.org/W3109551165","https://openalex.org/W3131390313","https://openalex.org/W3132201687","https://openalex.org/W3165878141","https://openalex.org/W3173365235","https://openalex.org/W3197290161","https://openalex.org/W3211341335","https://openalex.org/W4220825176","https://openalex.org/W4223591189","https://openalex.org/W4280619985","https://openalex.org/W4281490096","https://openalex.org/W4312087240"],"related_works":["https://openalex.org/W1971424770","https://openalex.org/W2111842731","https://openalex.org/W2066467839","https://openalex.org/W2594299395","https://openalex.org/W2771541573","https://openalex.org/W2765794416","https://openalex.org/W2170506381","https://openalex.org/W2039666944","https://openalex.org/W1531630856","https://openalex.org/W2794350630"],"abstract_inverted_index":{"Simulation":[0],"codes":[1],"can":[2],"be":[3],"accessed":[4],"at":[5],"https://github.com/Junkkkk/wGEE_GWAS.":[6]},"counts_by_year":[{"year":2024,"cited_by_count":2}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2025-10-10T00:00:00"}