{"id":"https://openalex.org/W4385462826","doi":"https://doi.org/10.1093/bioinformatics/btad470","title":"ggpicrust2: an R package for PICRUSt2 predicted functional profile analysis and visualization","display_name":"ggpicrust2: an R package for PICRUSt2 predicted functional profile analysis and visualization","publication_year":2023,"publication_date":"2023-08-01","ids":{"openalex":"https://openalex.org/W4385462826","doi":"https://doi.org/10.1093/bioinformatics/btad470","pmid":"https://pubmed.ncbi.nlm.nih.gov/37527009"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btad470","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad470","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad470/51016576/btad470.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad470/51016576/btad470.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101641857","display_name":"Yang Chen","orcid":"https://orcid.org/0009-0009-9151-2901"},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Yang","raw_affiliation_strings":["Department of Biostatistics, Southern Medical University , Guangzhou 510515, China","Department of Biostatistics, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":"https://orcid.org/0009-0009-9151-2901","affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Southern Medical University , Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Biostatistics, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086475796","display_name":"Jiahao Mai","orcid":"https://orcid.org/0009-0002-6789-0805"},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiahao Mai","raw_affiliation_strings":["Department of Biostatistics, Southern Medical University , Guangzhou 510515, China","Department of Biostatistics, Southern Medical University, Guangzhou, 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Southern Medical University , Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Biostatistics, Southern Medical University, Guangzhou, 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062749686","display_name":"Xuan Cao","orcid":"https://orcid.org/0000-0002-6859-0030"},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuan Cao","raw_affiliation_strings":["Department of Mathematical Sciences, University of Cincinnati , Cincinnati, OH 45221, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, University of Cincinnati , Cincinnati, OH 45221, United States","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046144701","display_name":"Aaron Burberry","orcid":"https://orcid.org/0000-0003-1552-8695"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Burberry","raw_affiliation_strings":["Department of Pathology, School of Medicine, Case Western Reserve University , Cleveland, OH 44106, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, Case Western Reserve University , Cleveland, OH 44106, United States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008150296","display_name":"Fabio Cominelli","orcid":"https://orcid.org/0000-0002-1571-1548"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fabio Cominelli","raw_affiliation_strings":["Case Digestive Health Research Institute, Case Western Reserve University , Cleveland, OH 44016, United States","Department of Pathology, School of Medicine, Case Western Reserve University , Cleveland, OH 44106, United States"],"raw_orcid":"https://orcid.org/0000-0002-1571-1548","affiliations":[{"raw_affiliation_string":"Case Digestive Health Research Institute, Case Western Reserve University , Cleveland, OH 44016, United States","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Pathology, School of Medicine, Case Western Reserve University , Cleveland, OH 44106, United States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100379639","display_name":"Liangliang Zhang","orcid":"https://orcid.org/0000-0001-5986-2260"},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I4390039247","display_name":"Case Comprehensive Cancer Center","ror":"https://ror.org/00fpjq451","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039247","https://openalex.org/I58956616"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Liangliang Zhang","raw_affiliation_strings":["Case Comprehensive Cancer Center , Cleveland, OH 44106, United States","Department of Population and Quantitative Health Sciences, Case Western Reserve University , Cleveland, OH 44106, United States"],"raw_orcid":"https://orcid.org/0000-0001-5986-2260","affiliations":[{"raw_affiliation_string":"Case Comprehensive Cancer Center , Cleveland, OH 44106, United States","institution_ids":["https://openalex.org/I4210108791","https://openalex.org/I4390039247"]},{"raw_affiliation_string":"Department of Population and Quantitative Health Sciences, Case Western Reserve University , Cleveland, OH 44106, United States","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100379639"],"corresponding_institution_ids":["https://openalex.org/I4210108791","https://openalex.org/I4390039247","https://openalex.org/I58956616"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":52.613,"has_fulltext":true,"cited_by_count":268,"citation_normalized_percentile":{"value":0.99972401,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"39","issue":"8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11791","display_name":"Microbial Community Ecology and Physiology","score":0.6287999749183655,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11791","display_name":"Microbial Community Ecology and Physiology","score":0.6287999749183655,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.20110000669956207,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.019600000232458115,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbiome","display_name":"Microbiome","score":0.8686610460281372},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.6909988522529602},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6669207811355591},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6518017053604126},{"id":"https://openalex.org/keywords/r-package","display_name":"R package","score":0.5905977487564087},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5116720199584961},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.47130048274993896},{"id":"https://openalex.org/keywords/metagenomics","display_name":"Metagenomics","score":0.44569846987724304},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.41744494438171387},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.355649471282959},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3242947459220886},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.30711060762405396},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.28641244769096375},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.22435852885246277},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.13534018397331238}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.8686610460281372},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6909988522529602},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6669207811355591},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6518017053604126},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.5905977487564087},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5116720199584961},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.47130048274993896},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.44569846987724304},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.41744494438171387},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.355649471282959},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3242947459220886},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30711060762405396},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.28641244769096375},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.22435852885246277},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13534018397331238},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btad470","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad470","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad470/51016576/btad470.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37527009","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37527009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10425198","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10425198","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10425198/pdf/btad470.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btad470","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad470","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad470/51016576/btad470.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4855236095","display_name":null,"funder_award_id":"P30 AG072959","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8637711573","display_name":null,"funder_award_id":"R01 DK042191","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320323421","display_name":"G\u00f6teborgs Universitet","ror":"https://ror.org/01tm6cn81"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4385462826.pdf"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1523266228","https://openalex.org/W1973158119","https://openalex.org/W1991669423","https://openalex.org/W2026006003","https://openalex.org/W2041282815","https://openalex.org/W2074466695","https://openalex.org/W2108818539","https://openalex.org/W2110300022","https://openalex.org/W2114104545","https://openalex.org/W2133856765","https://openalex.org/W2146512944","https://openalex.org/W2153109441","https://openalex.org/W2179438025","https://openalex.org/W2767984705","https://openalex.org/W2999175750","https://openalex.org/W3026019136","https://openalex.org/W3030441098","https://openalex.org/W3031621681","https://openalex.org/W3043062835","https://openalex.org/W3045153201","https://openalex.org/W3046991322","https://openalex.org/W3088375181","https://openalex.org/W3141470266","https://openalex.org/W3193433002","https://openalex.org/W3211779138","https://openalex.org/W4205364647","https://openalex.org/W4283721142","https://openalex.org/W4292363402","https://openalex.org/W4307425304","https://openalex.org/W6631383449"],"related_works":["https://openalex.org/W638577851","https://openalex.org/W2968354375","https://openalex.org/W2359440920","https://openalex.org/W2889550857","https://openalex.org/W3013372948","https://openalex.org/W3135997498","https://openalex.org/W4242417330","https://openalex.org/W4388282505","https://openalex.org/W3198631238","https://openalex.org/W3139084279"],"abstract_inverted_index":{"SUMMARY:":[0],"Microbiome":[1],"research":[2],"is":[3,50,204,213,222],"now":[4],"moving":[5],"beyond":[6],"the":[7,30,53,62,72,79,114,135,192,207],"compositional":[8],"analysis":[9,49],"of":[10,27,52,81,103,107,113,195],"microbial":[11,63,197],"taxa":[12],"in":[13,29,78,137],"a":[14,57],"sample.":[15],"Increasing":[16],"evidence":[17],"from":[18,155],"large":[19],"human":[20],"microbiome":[21,32,91],"studies":[22],"suggests":[23],"that":[24,75,175],"functional":[25,73,117,152,178,193],"consequences":[26],"changes":[28],"intestinal":[31],"may":[33],"provide":[34,68],"more":[35],"power":[36],"for":[37,150],"studying":[38],"their":[39,196],"impact":[40],"on":[41],"inflammation":[42],"and":[43,56,170,187,209,212,217],"immune":[44],"responses.":[45],"Although":[46],"16S":[47,94,156],"rRNA":[48,95,157],"one":[51,112],"most":[54,115],"popular":[55,116],"cost-effective":[58],"method":[59],"to":[60,89,133,164],"profile":[61,118],"compositions,":[64],"marker-gene":[65],"sequencing":[66],"cannot":[67],"direct":[69],"information":[70],"about":[71],"genes":[74],"are":[76,131],"present":[77],"genomes":[80],"community":[82],"members.":[83],"Bioinformatic":[84],"tools":[85,130],"have":[86,144],"been":[87],"developed":[88,145],"predict":[90],"function":[92],"with":[93],"gene":[96],"data.":[97],"Among":[98],"them,":[99],"PICRUSt2":[100],"(Phylogenetic":[101],"Investigation":[102],"Communities":[104],"by":[105],"Reconstruction":[106],"Unobserved":[108],"States)":[109],"has":[110],"become":[111],"prediction":[119],"tools,":[120],"which":[121],"generates":[122],"community-wide":[123],"pathway":[124,138],"abundances.":[125],"However,":[126],"no":[127],"state-of-art":[128],"inference":[129],"available":[132,214,223],"test":[134],"differences":[136],"abundances":[139],"between":[140],"comparison":[141],"groups.":[142],"We":[143],"ggpicrust2,":[146,181],"an":[147],"R":[148],"package,":[149],"analyzing":[151],"profiles":[153],"derived":[154],"sequencing.":[158],"This":[159],"powerful":[160],"tool":[161],"enables":[162],"researchers":[163],"conduct":[165],"extensive":[166],"differential":[167],"abundance":[168],"analyses":[169],"generate":[171],"visually":[172],"appealing":[173],"visualizations":[174],"effectively":[176],"highlight":[177],"signals.":[179],"With":[180],"users":[182],"can":[183],"obtain":[184],"publishable":[185],"results":[186],"gain":[188],"deeper":[189],"insights":[190],"into":[191],"composition":[194],"communities.":[198],"AVAILABILITY":[199],"AND":[200],"IMPLEMENTATION:":[201],"The":[202],"package":[203],"open-source":[205],"under":[206],"MIT":[208],"file":[210],"license":[211],"at":[215,224],"CRAN":[216],"https://github.com/cafferychen777/ggpicrust2.":[218],"Its":[219],"shiny":[220],"web":[221],"https://a95dps-caffery-chen.shinyapps.io/ggpicrust2_shiny/.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":58},{"year":2025,"cited_by_count":121},{"year":2024,"cited_by_count":82},{"year":2023,"cited_by_count":7}],"updated_date":"2026-07-19T07:52:34.831488","created_date":"2025-10-10T00:00:00"}