{"id":"https://openalex.org/W4224288697","doi":"https://doi.org/10.1093/bioinformatics/btac282","title":"Underground metabolism as a rich reservoir for pathway engineering","display_name":"Underground metabolism as a rich reservoir for pathway engineering","publication_year":2022,"publication_date":"2022-04-14","ids":{"openalex":"https://openalex.org/W4224288697","doi":"https://doi.org/10.1093/bioinformatics/btac282","pmid":"https://pubmed.ncbi.nlm.nih.gov/35441658"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btac282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3070/43857756/btac282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3070/43857756/btac282.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070051379","display_name":"Szabolcs Cselg\u0151 Kov\u00e1cs","orcid":"https://orcid.org/0000-0001-5916-0189"},"institutions":[{"id":"https://openalex.org/I2800351701","display_name":"HUN-REN Szegedi Biol\u00f3giai Kutat\u00f3k\u00f6zpont","ror":"https://ror.org/016gb1631","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4210103004","display_name":"Institute of Biochemistry","ror":"https://ror.org/022dvs210","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4387152226","display_name":"Hungarian Research Network","ror":"https://ror.org/04w6pnc49","country_code":"HU","type":"other","lineage":["https://openalex.org/I4387152226"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Szabolcs Cselg\u0151 Kov\u00e1cs","raw_affiliation_strings":["Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary"],"affiliations":[{"raw_affiliation_string":"Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I4387152226"]},{"raw_affiliation_string":"HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042390756","display_name":"Bal\u00e1zs Szappanos","orcid":"https://orcid.org/0000-0002-5075-1799"},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]},{"id":"https://openalex.org/I2800351701","display_name":"HUN-REN Szegedi Biol\u00f3giai Kutat\u00f3k\u00f6zpont","ror":"https://ror.org/016gb1631","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4210103004","display_name":"Institute of Biochemistry","ror":"https://ror.org/022dvs210","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4387152226","display_name":"Hungarian Research Network","ror":"https://ror.org/04w6pnc49","country_code":"HU","type":"other","lineage":["https://openalex.org/I4387152226"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Bal\u00e1zs Szappanos","raw_affiliation_strings":["Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","Department of Biotechnology, University of Szeged , Szeged, Hungary","HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary"],"affiliations":[{"raw_affiliation_string":"Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I4387152226"]},{"raw_affiliation_string":"Department of Biotechnology, University of Szeged , Szeged, Hungary","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060831245","display_name":"Roland Teng\u00f6lics","orcid":"https://orcid.org/0000-0002-1338-431X"},"institutions":[{"id":"https://openalex.org/I2800351701","display_name":"HUN-REN Szegedi Biol\u00f3giai Kutat\u00f3k\u00f6zpont","ror":"https://ror.org/016gb1631","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4210103004","display_name":"Institute of Biochemistry","ror":"https://ror.org/022dvs210","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4387152226","display_name":"Hungarian Research Network","ror":"https://ror.org/04w6pnc49","country_code":"HU","type":"other","lineage":["https://openalex.org/I4387152226"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Roland Teng\u00f6lics","raw_affiliation_strings":["Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary"],"affiliations":[{"raw_affiliation_string":"Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I4387152226"]},{"raw_affiliation_string":"HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069868522","display_name":"Richard A. Notebaart","orcid":"https://orcid.org/0000-0003-3469-1893"},"institutions":[{"id":"https://openalex.org/I913481162","display_name":"Wageningen University & Research","ror":"https://ror.org/04qw24q55","country_code":"NL","type":"education","lineage":["https://openalex.org/I913481162"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Richard A Notebaart","raw_affiliation_strings":["Food Microbiology, Wageningen University & Research , 6700 HB Wageningen, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Food Microbiology, Wageningen University & Research , 6700 HB Wageningen, The Netherlands","institution_ids":["https://openalex.org/I913481162"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031981177","display_name":"Bal\u00e1zs Papp","orcid":"https://orcid.org/0000-0003-3093-8852"},"institutions":[{"id":"https://openalex.org/I2800351701","display_name":"HUN-REN Szegedi Biol\u00f3giai Kutat\u00f3k\u00f6zpont","ror":"https://ror.org/016gb1631","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4210103004","display_name":"Institute of Biochemistry","ror":"https://ror.org/022dvs210","country_code":"HU","type":"facility","lineage":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I7597260"]},{"id":"https://openalex.org/I4387152226","display_name":"Hungarian Research Network","ror":"https://ror.org/04w6pnc49","country_code":"HU","type":"other","lineage":["https://openalex.org/I4387152226"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Bal\u00e1zs Papp","raw_affiliation_strings":["Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary"],"affiliations":[{"raw_affiliation_string":"Biological Research Centre, Institute of Biochemistry, Synthetic and Systems Biology Unit, E\u00f6tv\u00f6s Lor\u00e1nd Research Network (ELKH) , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I4387152226"]},{"raw_affiliation_string":"HCEMM-BRC Metabolic Systems Biology Lab , Szeged, Hungary","institution_ids":["https://openalex.org/I2800351701"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5031981177","https://openalex.org/A5042390756","https://openalex.org/A5069868522"],"corresponding_institution_ids":["https://openalex.org/I227486990","https://openalex.org/I2800351701","https://openalex.org/I4210103004","https://openalex.org/I4387152226","https://openalex.org/I913481162"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.0416,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.74469008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"38","issue":"11","first_page":"3070","last_page":"3077"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9939000010490417,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toolbox","display_name":"Toolbox","score":0.7026352286338806},{"id":"https://openalex.org/keywords/bioproduction","display_name":"Bioproduction","score":0.6731946468353271},{"id":"https://openalex.org/keywords/metabolic-engineering","display_name":"Metabolic engineering","score":0.5795916318893433},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.5601889491081238},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"Synthetic biology","score":0.48229244351387024},{"id":"https://openalex.org/keywords/heterologous","display_name":"Heterologous","score":0.47840675711631775},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.45791760087013245},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42333370447158813},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4228043854236603},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.40726640820503235},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.38065305352211},{"id":"https://openalex.org/keywords/biotechnology","display_name":"Biotechnology","score":0.2709897458553314},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.19947972893714905},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.11899352073669434},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11059793829917908},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.07200512290000916}],"concepts":[{"id":"https://openalex.org/C2777655017","wikidata":"https://www.wikidata.org/wiki/Q1501161","display_name":"Toolbox","level":2,"score":0.7026352286338806},{"id":"https://openalex.org/C2779227428","wikidata":"https://www.wikidata.org/wiki/Q4915219","display_name":"Bioproduction","level":2,"score":0.6731946468353271},{"id":"https://openalex.org/C6350086","wikidata":"https://www.wikidata.org/wiki/Q6822347","display_name":"Metabolic engineering","level":3,"score":0.5795916318893433},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.5601889491081238},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.48229244351387024},{"id":"https://openalex.org/C2780115692","wikidata":"https://www.wikidata.org/wiki/Q5747302","display_name":"Heterologous","level":3,"score":0.47840675711631775},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.45791760087013245},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42333370447158813},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4228043854236603},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40726640820503235},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.38065305352211},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.2709897458553314},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19947972893714905},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11899352073669434},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11059793829917908},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.07200512290000916}],"mesh":[{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053898","descriptor_name":"Biosynthetic Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053898","descriptor_name":"Biosynthetic Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053898","descriptor_name":"Biosynthetic Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060847","descriptor_name":"Metabolic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060847","descriptor_name":"Metabolic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060847","descriptor_name":"Metabolic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btac282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3070/43857756/btac282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35441658","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35441658","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:real.mtak.hu:149983","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400081","display_name":"Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210140733","host_organization_name":"Library and Information Centre of the Hungarian Academy of Sciences","host_organization_lineage":["https://openalex.org/I4210140733"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:library.wur.nl:wurpubs/600009","is_oa":true,"landing_page_url":"https://research.wur.nl/en/publications/underground-metabolism-as-a-rich-reservoir-for-pathway-engineerin","pdf_url":"https://edepot.wur.nl/574305","source":{"id":"https://openalex.org/S4210201231","display_name":"Socio-Environmental Systems Modeling","issn_l":"2663-3027","issn":["2663-3027"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1367-4803","raw_type":"Article/Letter to editor"},{"id":"pmh:oai:pubmedcentral.nih.gov:9154287","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9154287","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btac282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3070/43857756/btac282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1748000517","display_name":null,"funder_award_id":"NKFIH","funder_id":"https://openalex.org/F4320336675","funder_display_name":"National Research, Development and Innovation Office"},{"id":"https://openalex.org/G1817795474","display_name":null,"funder_award_id":"GINOP-2.3.2-15-2016-00026","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G2406933141","display_name":null,"funder_award_id":"KKP 129814","funder_id":"https://openalex.org/F4320336675","funder_display_name":"National Research, Development and Innovation Office"},{"id":"https://openalex.org/G2656064768","display_name":null,"funder_award_id":"LP2009-013/2012","funder_id":"https://openalex.org/F4320322192","funder_display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia"},{"id":"https://openalex.org/G340137887","display_name":null,"funder_award_id":"BO/00728/21/8","funder_id":"https://openalex.org/F4320322192","funder_display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia"},{"id":"https://openalex.org/G3707624019","display_name":null,"funder_award_id":"UNKP-21-5","funder_id":"https://openalex.org/F4320323476","funder_display_name":"Emberi Eroforr\u00e1sok Miniszt\u00e9riuma"},{"id":"https://openalex.org/G4063980791","display_name":null,"funder_award_id":"NKFIH-871-3/2020","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G42952139","display_name":null,"funder_award_id":"GINOP-2","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G5790050858","display_name":null,"funder_award_id":"PD 128271","funder_id":"https://openalex.org/F4320336675","funder_display_name":"National Research, Development and Innovation Office"},{"id":"https://openalex.org/G579486543","display_name":null,"funder_award_id":"GINOP-2.3.2","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G6119579825","display_name":null,"funder_award_id":"Janos Bolyai","funder_id":"https://openalex.org/F4320322192","funder_display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia"},{"id":"https://openalex.org/G650969681","display_name":null,"funder_award_id":"GINOP-2.3.2-15","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G7111068108","display_name":null,"funder_award_id":"GINOP-2.3.2-15-2","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G7329839912","display_name":null,"funder_award_id":"739593","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G736167370","display_name":null,"funder_award_id":"NKFIH-871-3/2020","funder_id":"https://openalex.org/F4320336675","funder_display_name":"National Research, Development and Innovation Office"},{"id":"https://openalex.org/G7540729865","display_name":null,"funder_award_id":"NKP-21-5","funder_id":"https://openalex.org/F4320326762","funder_display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal"},{"id":"https://openalex.org/G7541558665","display_name":null,"funder_award_id":"Bolyai","funder_id":"https://openalex.org/F4320322192","funder_display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia"},{"id":"https://openalex.org/G8051717526","display_name":null,"funder_award_id":"Grant","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8318064016","display_name":null,"funder_award_id":"Horizon","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322192","display_name":"Magyar Tudom\u00e1nyos Akad\u00e9mia","ror":"https://ror.org/02ks8qq67"},{"id":"https://openalex.org/F4320323476","display_name":"Emberi Eroforr\u00e1sok Miniszt\u00e9riuma","ror":"https://ror.org/00rb16m44"},{"id":"https://openalex.org/F4320326762","display_name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal","ror":null},{"id":"https://openalex.org/F4320329149","display_name":"Szegedi Tudom\u00e1nyegyetem","ror":"https://ror.org/01pnej532"},{"id":"https://openalex.org/F4320336675","display_name":"National Research, Development and Innovation Office","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4224288697.pdf","grobid_xml":"https://content.openalex.org/works/W4224288697.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1005466861","https://openalex.org/W1577825084","https://openalex.org/W1981890274","https://openalex.org/W2030979598","https://openalex.org/W2040819411","https://openalex.org/W2048465561","https://openalex.org/W2069090007","https://openalex.org/W2078355959","https://openalex.org/W2080249432","https://openalex.org/W2089121522","https://openalex.org/W2090863753","https://openalex.org/W2096004952","https://openalex.org/W2097882774","https://openalex.org/W2098390695","https://openalex.org/W2111905282","https://openalex.org/W2112737296","https://openalex.org/W2124737787","https://openalex.org/W2124962680","https://openalex.org/W2126097199","https://openalex.org/W2128312954","https://openalex.org/W2128746754","https://openalex.org/W2131504364","https://openalex.org/W2144779133","https://openalex.org/W2149481459","https://openalex.org/W2152572010","https://openalex.org/W2153668144","https://openalex.org/W2157741460","https://openalex.org/W2165612309","https://openalex.org/W2170427655","https://openalex.org/W2220904888","https://openalex.org/W2253334500","https://openalex.org/W2258782600","https://openalex.org/W2293809279","https://openalex.org/W2398042263","https://openalex.org/W2513603066","https://openalex.org/W2559588208","https://openalex.org/W2605253412","https://openalex.org/W2605504874","https://openalex.org/W2614960634","https://openalex.org/W2623898396","https://openalex.org/W2743063996","https://openalex.org/W2750644088","https://openalex.org/W2768490449","https://openalex.org/W2800771128","https://openalex.org/W2810239425","https://openalex.org/W2888961739","https://openalex.org/W2889436607","https://openalex.org/W2889665009","https://openalex.org/W2913261323","https://openalex.org/W2921389849","https://openalex.org/W2940402329","https://openalex.org/W2950160930","https://openalex.org/W2950223937","https://openalex.org/W2977870980","https://openalex.org/W2981670263","https://openalex.org/W3031753718","https://openalex.org/W3032479100","https://openalex.org/W3036284296","https://openalex.org/W3037758266","https://openalex.org/W3096046766","https://openalex.org/W3135416650","https://openalex.org/W3138458927","https://openalex.org/W4220662588","https://openalex.org/W4236515822","https://openalex.org/W4238473188","https://openalex.org/W6678783859"],"related_works":["https://openalex.org/W2917843259","https://openalex.org/W2009687716","https://openalex.org/W3025774783","https://openalex.org/W2126646394","https://openalex.org/W2885200473","https://openalex.org/W3047447888","https://openalex.org/W2053717739","https://openalex.org/W4320492055","https://openalex.org/W2298762068","https://openalex.org/W4311232369"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}