{"id":"https://openalex.org/W4223962268","doi":"https://doi.org/10.1093/bioinformatics/btac274","title":"DRUMMER\u2014rapid detection of RNA modifications through comparative nanopore sequencing","display_name":"DRUMMER\u2014rapid detection of RNA modifications through comparative nanopore sequencing","publication_year":2022,"publication_date":"2022-04-14","ids":{"openalex":"https://openalex.org/W4223962268","doi":"https://doi.org/10.1093/bioinformatics/btac274","pmid":"https://pubmed.ncbi.nlm.nih.gov/35426900"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btac274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac274","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3113/49878602/btac274.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3113/49878602/btac274.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046909452","display_name":"Jonathan S. Abebe","orcid":"https://orcid.org/0009-0000-1268-0427"},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan S Abebe","raw_affiliation_strings":["Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061068402","display_name":"Alexander M. Price","orcid":"https://orcid.org/0000-0003-4654-4604"},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander M Price","raw_affiliation_strings":["Division of Protective Immunity, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA"],"raw_orcid":"https://orcid.org/0000-0003-4654-4604","affiliations":[{"raw_affiliation_string":"Division of Protective Immunity, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015451664","display_name":"Katharina E. Hayer","orcid":"https://orcid.org/0000-0002-1463-3111"},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katharina E Hayer","raw_affiliation_strings":["Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA"],"raw_orcid":"https://orcid.org/0000-0002-1463-3111","affiliations":[{"raw_affiliation_string":"Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055851463","display_name":"Ian Mohr","orcid":"https://orcid.org/0000-0002-4921-1998"},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ian Mohr","raw_affiliation_strings":["Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020083972","display_name":"Matthew D. Weitzman","orcid":"https://orcid.org/0000-0001-9713-167X"},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew D Weitzman","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104, USA","Division of Protective Immunity, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA"],"raw_orcid":"https://orcid.org/0000-0001-9713-167X","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Division of Protective Immunity, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia , Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034902241","display_name":"Angus C. Wilson","orcid":"https://orcid.org/0000-0002-5016-4164"},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angus C Wilson","raw_affiliation_strings":["Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA"],"raw_orcid":"https://orcid.org/0000-0002-5016-4164","affiliations":[{"raw_affiliation_string":"Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036289658","display_name":"Daniel P. Depledge","orcid":"https://orcid.org/0000-0002-4292-0599"},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]},{"id":"https://openalex.org/I4210115305","display_name":"German Center for Infection Research","ror":"https://ror.org/028s4q594","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210115305","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"Daniel P Depledge","raw_affiliation_strings":["Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA","German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig , Hannover, Germany","Institute of Virology, Hannover Medical School , Hannover 30625, Germany"],"raw_orcid":"https://orcid.org/0000-0002-4292-0599","affiliations":[{"raw_affiliation_string":"Department of Microbiology, New York University School of Medicine , New York, NY 10016, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig , Hannover, Germany","institution_ids":["https://openalex.org/I4210115305"]},{"raw_affiliation_string":"Institute of Virology, Hannover Medical School , Hannover 30625, Germany","institution_ids":["https://openalex.org/I34809795"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5036289658"],"corresponding_institution_ids":["https://openalex.org/I34809795","https://openalex.org/I4210115305","https://openalex.org/I57206974"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":5.545,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.97191302,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"38","issue":"11","first_page":"3113","last_page":"3115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9430999755859375,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9430999755859375,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.04580000042915344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drummer","display_name":"Drummer","score":0.9538561105728149},{"id":"https://openalex.org/keywords/nanopore-sequencing","display_name":"Nanopore sequencing","score":0.5677009224891663},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5273270010948181},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.48083457350730896},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.45632317662239075},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.4531039893627167},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2834293246269226},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2297268509864807},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.22930389642715454},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.1469854712486267},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13688483834266663}],"concepts":[{"id":"https://openalex.org/C2777583168","wikidata":"https://www.wikidata.org/wiki/Q5309188","display_name":"Drummer","level":3,"score":0.9538561105728149},{"id":"https://openalex.org/C126513998","wikidata":"https://www.wikidata.org/wiki/Q8973627","display_name":"Nanopore sequencing","level":4,"score":0.5677009224891663},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5273270010948181},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48083457350730896},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.45632317662239075},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.4531039893627167},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2834293246269226},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2297268509864807},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.22930389642715454},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.1469854712486267},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13688483834266663},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0},{"id":"https://openalex.org/C175845324","wikidata":"https://www.wikidata.org/wiki/Q2738285","display_name":"Drum","level":2,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000081414","descriptor_name":"Nanopore Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000081414","descriptor_name":"Nanopore Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000081414","descriptor_name":"Nanopore Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000081414","descriptor_name":"Nanopore Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000081414","descriptor_name":"Nanopore Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btac274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac274","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3113/49878602/btac274.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35426900","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35426900","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9154255","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9154255","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btac274","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac274","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/11/3113/49878602/btac274.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1053610649","display_name":null,"funder_award_id":"R01 AI152543","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2290830064","display_name":null,"funder_award_id":"F32 AI138432","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2476700337","display_name":null,"funder_award_id":"R01 AI118891","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4254931121","display_name":null,"funder_award_id":"R01 GM056927","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4264408365","display_name":null,"funder_award_id":"R21 AI147163","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5276974928","display_name":null,"funder_award_id":"CA115299","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5727563649","display_name":null,"funder_award_id":"T32 CA115299","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5925835816","display_name":null,"funder_award_id":"R01 AI073898","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6063490895","display_name":null,"funder_award_id":"R01 AI121321","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G651058253","display_name":null,"funder_award_id":"R21 AI130618","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8739849507","display_name":null,"funder_award_id":"R01 AI145266","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4223962268.pdf","grobid_xml":"https://content.openalex.org/works/W4223962268.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W776567260","https://openalex.org/W2065847836","https://openalex.org/W2177784250","https://openalex.org/W2903793577","https://openalex.org/W2915489297","https://openalex.org/W2950063384","https://openalex.org/W2952628721","https://openalex.org/W2953460056","https://openalex.org/W2955930197","https://openalex.org/W2971454256","https://openalex.org/W2973421587","https://openalex.org/W2980511028","https://openalex.org/W2989499631","https://openalex.org/W2999689892","https://openalex.org/W3017173206","https://openalex.org/W3017326203","https://openalex.org/W3043981686","https://openalex.org/W3107659143","https://openalex.org/W3121941032","https://openalex.org/W3162353597","https://openalex.org/W3174878016","https://openalex.org/W3184504420","https://openalex.org/W3185272804","https://openalex.org/W3200997695","https://openalex.org/W4225743429","https://openalex.org/W4308772822","https://openalex.org/W6801446627"],"related_works":["https://openalex.org/W3151252822","https://openalex.org/W2149543804","https://openalex.org/W294148087","https://openalex.org/W2048369028","https://openalex.org/W2746163916","https://openalex.org/W4247672621","https://openalex.org/W1748271044","https://openalex.org/W4250907392","https://openalex.org/W2902387322","https://openalex.org/W3036186909"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1],"chemical":[2],"modification":[3],"of":[4,12,15,40,63,89,96,138,150],"ribonucleotides":[5],"regulates":[6],"the":[7,59,87,94,218],"structure,":[8],"stability":[9],"and":[10,61,81,125,153,173,189,200,211],"interactions":[11],"RNAs.":[13],"Profiling":[14],"these":[16,74],"modifications":[17,30,98],"using":[18],"short-read":[19],"(Illumina)":[20],"sequencing":[21,55],"techniques":[22],"provides":[23,127],"high":[24,162,198],"sensitivity":[25,168,199],"but":[26],"low-to-medium":[27],"resolution":[28],"i.e.":[29],"cannot":[31],"be":[32],"assigned":[33],"to":[34,57,86,157,169],"specific":[35],"transcript":[36],"isoforms":[37],"in":[38,49,99,143,208,217],"regions":[39],"sequence":[41],"overlap.":[42],"An":[43],"alternative":[44,111,129],"strategy":[45],"uses":[46],"current":[47],"fluctuations":[48,118],"nanopore-based":[50],"long":[51],"read":[52],"direct":[53],"RNA":[54,97],"(DRS)":[56],"infer":[58],"location":[60],"identity":[62],"nucleotides":[64,160],"that":[65,116,194],"differ":[66],"between":[67],"two":[68],"experimental":[69],"conditions.":[70],"While":[71],"highly":[72],"sensitive,":[73],"signal-level":[75,170],"analyses":[76],"require":[77],"high-quality":[78],"transcriptome":[79],"annotations":[80,108],"thus":[82,126],"are":[83,226],"best":[84],"suited":[85],"study":[88],"model":[90],"organisms.":[91],"By":[92],"contrast,":[93],"detection":[95],"microbial":[100],"organisms":[101],"which":[102],"typically":[103],"have":[104],"no":[105],"or":[106],"low-quality":[107],"requires":[109],"an":[110,128],"strategy.":[112],"Here,":[113],"we":[114,192],"demonstrate":[115,193],"signal":[117],"directly":[119],"influence":[120],"error":[121],"rates":[122],"during":[123],"base-calling":[124],"approach":[130],"for":[131],"identifying":[132],"modified":[133,159],"nucleotides.":[134],"RESULTS:":[135],"DRUMMER":[136,195,205],"(Detection":[137],"Ribonucleic":[139],"acid":[140],"Modifications":[141],"Manifested":[142],"Error":[144],"Rates)":[145],"(i)":[146],"utilizes":[147],"a":[148],"range":[149],"statistical":[151],"tests":[152],"background":[154],"noise":[155],"correction":[156],"identify":[158],"with":[161,166,178,197],"confidence,":[163],"(ii)":[164],"operates":[165,196],"similar":[167],"analysis":[171],"approaches":[172],"(iii)":[174],"correlates":[175],"very":[176],"well":[177],"orthogonal":[179],"approaches.":[180],"Using":[181],"well-characterized":[182],"DRS":[183],"datasets":[184,191],"supported":[185],"by":[186],"independent":[187],"meRIP-Seq":[188],"miCLIP-Seq":[190],"specificity.":[201],"AVAILABILITY":[202],"AND":[203],"IMPLEMENTATION:":[204],"is":[206,212],"written":[207],"Python":[209],"3":[210],"available":[213,227],"as":[214],"open":[215],"source":[216],"GitHub":[219],"repository:":[220],"https://github.com/DepledgeLab/DRUMMER.":[221],"SUPPLEMENTARY":[222],"INFORMATION:":[223],"Supplementary":[224],"data":[225],"at":[228],"Bioinformatics":[229],"online.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":7}],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2025-10-10T00:00:00"}