{"id":"https://openalex.org/W4226383395","doi":"https://doi.org/10.1093/bioinformatics/btac253","title":"Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations","display_name":"Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations","publication_year":2022,"publication_date":"2022-04-15","ids":{"openalex":"https://openalex.org/W4226383395","doi":"https://doi.org/10.1093/bioinformatics/btac253","pmid":"https://pubmed.ncbi.nlm.nih.gov/35758777"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btac253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac253","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/bioinformatics/btac253","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087796220","display_name":"Xuecong Fu","orcid":"https://orcid.org/0000-0001-7126-7763"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuecong Fu","raw_affiliation_strings":["Department of Biological Sciences, Carnegie Mellon University , Pittsburgh, PA 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Carnegie Mellon University , Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015600863","display_name":"Haoyun Lei","orcid":"https://orcid.org/0000-0001-7690-7053"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haoyun Lei","raw_affiliation_strings":["Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052422214","display_name":"Yifeng Tao","orcid":"https://orcid.org/0000-0001-5076-0081"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yifeng Tao","raw_affiliation_strings":["Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051953313","display_name":"Russell Schwartz","orcid":"https://orcid.org/0000-0002-4970-2252"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Russell Schwartz","raw_affiliation_strings":["Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA","Department of Biological Sciences, Carnegie Mellon University , Pittsburgh, PA 15213, USA"],"raw_orcid":"https://orcid.org/0000-0002-4970-2252","affiliations":[{"raw_affiliation_string":"Computational Biology Department, Carnegie Mellon University , Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Department of Biological Sciences, Carnegie Mellon University , Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I74973139"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051953313"],"corresponding_institution_ids":["https://openalex.org/I74973139"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":2.0873,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.88498382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"38","issue":"Supplement_1","first_page":"i125","last_page":"i133"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.958299994468689,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.958299994468689,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.6687957644462585},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6548192501068115},{"id":"https://openalex.org/keywords/somatic-evolution-in-cancer","display_name":"Somatic evolution in cancer","score":0.5885847806930542},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"Copy-number variation","score":0.5880796313285828},{"id":"https://openalex.org/keywords/subtyping","display_name":"Subtyping","score":0.575104296207428},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5637832880020142},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5528643727302551},{"id":"https://openalex.org/keywords/phylogenetics","display_name":"Phylogenetics","score":0.541192889213562},{"id":"https://openalex.org/keywords/indel","display_name":"Indel","score":0.47185349464416504},{"id":"https://openalex.org/keywords/lineage","display_name":"Lineage (genetic)","score":0.4704935550689697},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3909303545951843},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.38798218965530396},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.29969412088394165},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2544315457344055},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.21258258819580078},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.19594663381576538},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.15313193202018738},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.11911901831626892},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.08322766423225403}],"concepts":[{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.6687957644462585},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6548192501068115},{"id":"https://openalex.org/C113968399","wikidata":"https://www.wikidata.org/wiki/Q7559241","display_name":"Somatic evolution in cancer","level":3,"score":0.5885847806930542},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.5880796313285828},{"id":"https://openalex.org/C83852419","wikidata":"https://www.wikidata.org/wiki/Q2713292","display_name":"Subtyping","level":2,"score":0.575104296207428},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5637832880020142},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5528643727302551},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.541192889213562},{"id":"https://openalex.org/C119054055","wikidata":"https://www.wikidata.org/wiki/Q1576681","display_name":"Indel","level":5,"score":0.47185349464416504},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.4704935550689697},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3909303545951843},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.38798218965530396},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.29969412088394165},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2544315457344055},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.21258258819580078},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.19594663381576538},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15313193202018738},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.11911901831626892},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.08322766423225403},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009711","descriptor_name":"Nucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060965","descriptor_name":"Clonal Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060965","descriptor_name":"Clonal Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060965","descriptor_name":"Clonal Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btac253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac253","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35758777","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35758777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9236577","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9236577","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btac253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btac253","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4680157736","display_name":null,"funder_award_id":"R01 HG010589","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G8479198572","display_name":null,"funder_award_id":"FP00003273","funder_id":"https://openalex.org/F4320308109","funder_display_name":"Pennsylvania Department of Health"}],"funders":[{"id":"https://openalex.org/F4320308109","display_name":"Pennsylvania Department of Health","ror":"https://ror.org/00ra1fg11"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1967304777","https://openalex.org/W2015182193","https://openalex.org/W2016661249","https://openalex.org/W2025759727","https://openalex.org/W2032518018","https://openalex.org/W2042536531","https://openalex.org/W2050146329","https://openalex.org/W2111874706","https://openalex.org/W2122392334","https://openalex.org/W2124810156","https://openalex.org/W2127214385","https://openalex.org/W2156411023","https://openalex.org/W2164844813","https://openalex.org/W2482614962","https://openalex.org/W2515472395","https://openalex.org/W2579382924","https://openalex.org/W2586389371","https://openalex.org/W2588969809","https://openalex.org/W2793271470","https://openalex.org/W2802092881","https://openalex.org/W2802415313","https://openalex.org/W2980515223","https://openalex.org/W2980586637","https://openalex.org/W2991385399","https://openalex.org/W3004584205","https://openalex.org/W3012247811","https://openalex.org/W3017999335","https://openalex.org/W3081916416","https://openalex.org/W3183370121","https://openalex.org/W3202097074","https://openalex.org/W6676554921","https://openalex.org/W6684348521"],"related_works":["https://openalex.org/W2396009657","https://openalex.org/W2799110842","https://openalex.org/W3032826521","https://openalex.org/W2391332606","https://openalex.org/W1462775415","https://openalex.org/W1987896487","https://openalex.org/W4229853287","https://openalex.org/W1535483699","https://openalex.org/W2333832190","https://openalex.org/W2068445477"],"abstract_inverted_index":{"MOTIVATION:":[0],"Cancer":[1],"develops":[2],"through":[3,21,113],"a":[4,72,84,138],"process":[5],"of":[6,24,103],"clonal":[7,129,141],"evolution":[8,56],"in":[9,100],"which":[10,77],"an":[11],"initially":[12],"healthy":[13],"cell":[14],"gives":[15],"rise":[16],"to":[17,63,115,124],"progeny":[18],"gradually":[19],"differentiating":[20],"the":[22,94,101,111],"accumulation":[23],"genetic":[25],"and":[26,81,128],"epigenetic":[27],"mutations.":[28],"These":[29],"mutations":[30],"can":[31,136],"take":[32],"various":[33],"forms,":[34],"including":[35],"single-nucleotide":[36],"variants":[37],"(SNVs),":[38],"copy":[39],"number":[40],"alterations":[41],"(CNAs)":[42],"or":[43,154],"structural":[44],"variations":[45],"(SVs),":[46],"with":[47,131,150],"each":[48],"variant":[49,106,134],"type":[50],"providing":[51],"complementary":[52],"insights":[53],"into":[54,83],"tumor":[55,73,118],"as":[57,59],"well":[58],"offering":[60],"distinct":[61],"challenges":[62],"phylogenetic":[64],"inference.":[65],"RESULTS:":[66],"In":[67],"this":[68],"work,":[69,148],"we":[70],"develop":[71],"phylogeny":[74,126],"method,":[75],"TUSV-ext,":[76],"incorporates":[78],"SNVs,":[79],"CNAs":[80],"SVs":[82],"single":[85],"inference":[86,127],"framework.":[87],"We":[88,108],"demonstrate":[89,110],"on":[90],"simulated":[91],"data":[92,163],"that":[93],"method":[95,112],"produces":[96],"accurate":[97],"tree":[98],"inferences":[99],"presence":[102],"all":[104,132],"three":[105,133],"types.":[107],"further":[109],"application":[114],"real":[116],"prostate":[117],"data,":[119],"showing":[120],"how":[121],"our":[122],"approach":[123],"coordinated":[125],"construction":[130],"types":[135],"reveal":[137],"more":[139],"complicated":[140],"structure":[142],"than":[143],"is":[144],"suggested":[145],"by":[146],"prior":[147],"consistent":[149],"extensive":[151],"polyclonal":[152],"seeding":[153],"migration.":[155],"AVAILABILITY":[156],"AND":[157],"IMPLEMENTATION:":[158],"https://github.com/CMUSchwartzLab/TUSV-ext.":[159],"SUPPLEMENTARY":[160],"INFORMATION:":[161],"Supplementary":[162],"are":[164],"available":[165],"at":[166],"Bioinformatics":[167],"online.":[168]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}