{"id":"https://openalex.org/W3205916474","doi":"https://doi.org/10.1093/bioinformatics/btab703","title":"MCRL: using a reference library to compress a metagenome into a non-redundant list of sequences, considering viruses as a case study","display_name":"MCRL: using a reference library to compress a metagenome into a non-redundant list of sequences, considering viruses as a case study","publication_year":2021,"publication_date":"2021-10-08","ids":{"openalex":"https://openalex.org/W3205916474","doi":"https://doi.org/10.1093/bioinformatics/btab703","mag":"3205916474","pmid":"https://pubmed.ncbi.nlm.nih.gov/34636854"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab703","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab703","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/3/631/42166986/btab703.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/38/3/631/42166986/btab703.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014099223","display_name":"Arbel D. Tadmor","orcid":"https://orcid.org/0000-0003-1617-2010"},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]},{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"Arbel D Tadmor","raw_affiliation_strings":["Department of Biochemistry and Molecular Biophysics, California Institute of Technology , Pasadena, CA 91125, USA","TRON - Translational Oncology at the University Medical Center of Johannes Gutenberg University, 55131 Mainz, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1617-2010","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biophysics, California Institute of Technology , Pasadena, CA 91125, USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"TRON - Translational Oncology at the University Medical Center of Johannes Gutenberg University, 55131 Mainz, Germany","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I4210094062"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029612834","display_name":"Rob Phillips","orcid":"https://orcid.org/0000-0003-3082-2809"},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rob Phillips","raw_affiliation_strings":["Department of Applied Physics, California Institute of Technology , Pasadena, CA 91125, USA","Department of Bioengineering, California Institute of Technology , Pasadena, CA 91125, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, California Institute of Technology , Pasadena, CA 91125, USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Department of Bioengineering, California Institute of Technology , Pasadena, CA 91125, USA","institution_ids":["https://openalex.org/I122411786"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5014099223"],"corresponding_institution_ids":["https://openalex.org/I122411786","https://openalex.org/I197323543","https://openalex.org/I4210094062"],"apc_list":{"value":3478,"currency":"USD","value_usd":3478},"apc_paid":null,"fwci":0.3731,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.56332668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"38","issue":"3","first_page":"631","last_page":"647"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.604200005531311,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.604200005531311,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.11980000138282776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.07500000298023224,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metagenomics","display_name":"Metagenomics","score":0.8628415465354919},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6443271636962891},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5644187927246094},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.47844555974006653},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3730209469795227},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3432449996471405},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.32495254278182983},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2149006724357605},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07862550020217896}],"concepts":[{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.8628415465354919},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6443271636962891},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5644187927246094},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.47844555974006653},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3730209469795227},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3432449996471405},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.32495254278182983},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2149006724357605},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07862550020217896}],"mesh":[{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056186","descriptor_name":"Metagenomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btab703","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab703","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/3/631/42166986/btab703.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34636854","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34636854","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10060711","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10060711","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10060711/pdf/btab703.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:authors.library.caltech.edu:113194","is_oa":false,"landing_page_url":"https://resolver.caltech.edu/CaltechAUTHORS:20220201-508256000","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btab703","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab703","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/38/3/631/42166986/btab703.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6715595249","display_name":"NIH Director's Pioneer Award (RMI)","funder_award_id":"5dp1od000217-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7628921743","display_name":null,"funder_award_id":"R01 GM098465","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320338388","display_name":"Eurostars","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3205916474.pdf","grobid_xml":"https://content.openalex.org/works/W3205916474.grobid-xml"},"referenced_works_count":96,"referenced_works":["https://openalex.org/W30236741","https://openalex.org/W1496933752","https://openalex.org/W1603910045","https://openalex.org/W1648007346","https://openalex.org/W1921607560","https://openalex.org/W1964106002","https://openalex.org/W1964640602","https://openalex.org/W1966952999","https://openalex.org/W1975970608","https://openalex.org/W1989348205","https://openalex.org/W1998621989","https://openalex.org/W2018686814","https://openalex.org/W2021210077","https://openalex.org/W2027496182","https://openalex.org/W2031893281","https://openalex.org/W2035322315","https://openalex.org/W2040263545","https://openalex.org/W2042626827","https://openalex.org/W2045000440","https://openalex.org/W2045204781","https://openalex.org/W2047817180","https://openalex.org/W2062296203","https://openalex.org/W2063756105","https://openalex.org/W2076048958","https://openalex.org/W2082418604","https://openalex.org/W2088347903","https://openalex.org/W2090610796","https://openalex.org/W2096525273","https://openalex.org/W2097124003","https://openalex.org/W2097597464","https://openalex.org/W2097771307","https://openalex.org/W2099837668","https://openalex.org/W2107903949","https://openalex.org/W2108211735","https://openalex.org/W2108718991","https://openalex.org/W2111373249","https://openalex.org/W2116423958","https://openalex.org/W2123948195","https://openalex.org/W2124351063","https://openalex.org/W2131415145","https://openalex.org/W2133790733","https://openalex.org/W2134852597","https://openalex.org/W2137390232","https://openalex.org/W2137597742","https://openalex.org/W2137662380","https://openalex.org/W2141626941","https://openalex.org/W2141885858","https://openalex.org/W2142678478","https://openalex.org/W2143210482","https://openalex.org/W2145853890","https://openalex.org/W2150860043","https://openalex.org/W2152301430","https://openalex.org/W2155368965","https://openalex.org/W2156125289","https://openalex.org/W2158714788","https://openalex.org/W2159482845","https://openalex.org/W2160209604","https://openalex.org/W2160681728","https://openalex.org/W2169659701","https://openalex.org/W2170747616","https://openalex.org/W2171124586","https://openalex.org/W2194764270","https://openalex.org/W2214186913","https://openalex.org/W2257287664","https://openalex.org/W2273522830","https://openalex.org/W2321452352","https://openalex.org/W2328346769","https://openalex.org/W2419548415","https://openalex.org/W2465681871","https://openalex.org/W2514983714","https://openalex.org/W2521298622","https://openalex.org/W2525128349","https://openalex.org/W2557776122","https://openalex.org/W2580983456","https://openalex.org/W2593728374","https://openalex.org/W2602765986","https://openalex.org/W2898120697","https://openalex.org/W2900102202","https://openalex.org/W2900984733","https://openalex.org/W2941799199","https://openalex.org/W2951274106","https://openalex.org/W2952620784","https://openalex.org/W2991012415","https://openalex.org/W3145289798","https://openalex.org/W4210400672","https://openalex.org/W4237114091","https://openalex.org/W4239871258","https://openalex.org/W4242996820","https://openalex.org/W4248735723","https://openalex.org/W4294216483","https://openalex.org/W6641676196","https://openalex.org/W6677311404","https://openalex.org/W6680215730","https://openalex.org/W6680677623","https://openalex.org/W6701457376","https://openalex.org/W6735740338"],"related_works":["https://openalex.org/W2210738511","https://openalex.org/W2487541429","https://openalex.org/W1910109602","https://openalex.org/W2080583581","https://openalex.org/W4297131566","https://openalex.org/W2017364432","https://openalex.org/W2329606903","https://openalex.org/W3156493549","https://openalex.org/W3195915274","https://openalex.org/W3158976456"],"abstract_inverted_index":{"MOTIVATION:":[0],"Metagenomes":[1],"offer":[2],"a":[3,12,23,31,38,47,59,63,96,120,129,168],"glimpse":[4],"into":[5],"the":[6,103,107,150,179,218,228],"total":[7],"genomic":[8],"diversity":[9],"contained":[10],"within":[11],"sample.":[13],"Currently,":[14],"however,":[15],"there":[16,156],"is":[17,68,128,157],"no":[18,158],"straightforward":[19],"way":[20],"to":[21,72,77,84,136,162,164,172,193],"obtain":[22],"non-redundant":[24,130],"list":[25,131],"of":[26,30,33,65,87,115,125,132,140,223],"all":[27],"putative":[28],"homologs":[29],"set":[32,64],"reference":[34,55,60,66,81,104,117,133],"sequences":[35],"present":[36,148],"in":[37,95,149,178],"metagenome.":[39,75,151],"RESULTS:":[40],"To":[41],"address":[42],"this":[43,126],"problem,":[44],"we":[45],"developed":[46],"novel":[48],"clustering":[49,53,154],"approach":[50],"called":[51],"'metagenomic":[52],"by":[54],"library'":[56],"(MCRL),":[57],"where":[58],"library":[61],"containing":[62],"genes":[67,82,105,118,134],"clustered":[69,94],"with":[70,167,235],"respect":[71],"an":[73,200,204],"assembled":[74],"According":[76],"our":[78,224],"proposed":[79,225],"approach,":[80],"homologous":[83,135],"similar":[85],"sets":[86,139],"metagenomic":[88,153],"sequences,":[89],"termed":[90],"'signatures',":[91],"are":[92,247],"iteratively":[93],"greedy":[97],"fashion,":[98],"retaining":[99],"at":[100,249],"each":[101],"step":[102],"yielding":[106],"lowest":[108],"E":[109],"values,":[110],"and":[111,203,221,232],"terminating":[112],"when":[113,181],"signatures":[114],"remaining":[116],"have":[119],"minimal":[121],"overlap.":[122],"The":[123],"outcome":[124],"computation":[127],"minimally":[137],"overlapping":[138],"contigs,":[141],"representing":[142],"potential":[143],"candidates":[144],"for":[145,160,227],"gene":[146,184,197],"families":[147,198],"Unlike":[152],"methods,":[155],"need":[159],"contigs":[161],"overlap":[163],"be":[165,191,211],"associated":[166],"cluster,":[169],"enabling":[170],"MCRL":[171,189],"draw":[173],"on":[174],"more":[175],"information":[176],"encoded":[177],"metagenome":[180,202],"computing":[182],"tentative":[183],"families.":[185],"We":[186,216],"demonstrate":[187],"how":[188],"can":[190],"used":[192],"extract":[194],"candidate":[195],"viral":[196,229],"from":[199],"oral":[201,205],"virome":[206],"that":[207],"otherwise":[208],"could":[209],"not":[210],"determined":[212],"using":[213],"standard":[214],"approaches.":[215,238],"evaluate":[217],"sensitivity,":[219],"accuracy":[220],"robustness":[222],"method":[226],"case":[230],"study":[231],"compare":[233],"it":[234],"existing":[236],"analysis":[237],"AVAILABILITY":[239],"AND":[240],"IMPLEMENTATION:":[241],"https://github.com/a-tadmor/MCRL.":[242],"SUPPLEMENTARY":[243],"INFORMATION:":[244],"Supplementary":[245],"data":[246],"available":[248],"Bioinformatics":[250],"online.":[251]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-09-05T08:02:43.246662","created_date":"2025-10-10T00:00:00"}