{"id":"https://openalex.org/W3197696221","doi":"https://doi.org/10.1093/bioinformatics/btab643","title":"Structure-aware protein\u2013protein interaction site prediction using deep graph convolutional network","display_name":"Structure-aware protein\u2013protein interaction site prediction using deep graph convolutional network","publication_year":2021,"publication_date":"2021-09-08","ids":{"openalex":"https://openalex.org/W3197696221","doi":"https://doi.org/10.1093/bioinformatics/btab643","mag":"3197696221","pmid":"https://pubmed.ncbi.nlm.nih.gov/34498061"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab643","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab643","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079232368","display_name":"Qianmu Yuan","orcid":"https://orcid.org/0000-0001-6098-9103"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianmu Yuan","raw_affiliation_strings":["School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China","institution_ids":["https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100689463","display_name":"Jianwen Chen","orcid":"https://orcid.org/0000-0001-7999-2070"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianwen Chen","raw_affiliation_strings":["School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China","institution_ids":["https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076568855","display_name":"Huiying Zhao","orcid":"https://orcid.org/0000-0001-9429-3016"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiying Zhao","raw_affiliation_strings":["Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou 510000, China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou 510000, China","institution_ids":["https://openalex.org/I4210097354","https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032724151","display_name":"Yaoqi Zhou","orcid":"https://orcid.org/0000-0002-9958-5699"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]},{"id":"https://openalex.org/I4210102541","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210102541"]},{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["AU","CN"],"is_corresponding":true,"raw_author_name":"Yaoqi Zhou","raw_affiliation_strings":["Institute for Glycomics, Griffith University, Parklands Drive , Southport, QLD 4215, Australia","Peking University Shenzhen Graduate School , Shenzhen 518055, China","Shenzhen Bay Laboratory , Shenzhen 518055, China","Institute for Glycomics, Griffith University, Parklands Drive, Southport, Queensland 4215, Australia"],"affiliations":[{"raw_affiliation_string":"Institute for Glycomics, Griffith University, Parklands Drive , Southport, QLD 4215, Australia","institution_ids":["https://openalex.org/I11701301"]},{"raw_affiliation_string":"Peking University Shenzhen Graduate School , Shenzhen 518055, China","institution_ids":["https://openalex.org/I4210128628"]},{"raw_affiliation_string":"Shenzhen Bay Laboratory , Shenzhen 518055, China","institution_ids":["https://openalex.org/I4210102541"]},{"raw_affiliation_string":"Institute for Glycomics, Griffith University, Parklands Drive, Southport, Queensland 4215, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023539493","display_name":"Yuedong Yang","orcid":"https://orcid.org/0000-0002-6782-2813"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuedong Yang","raw_affiliation_strings":["Key Laboratory of Machine Intelligence and Advanced Computing of MOE, Sun Yat-sen University , Guangzhou 510000, China","School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China","Key Laboratory of Machine Intelligence and Advanced Computing of MOE, Sun Yat-sen University, Guang-zhou 510000, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Machine Intelligence and Advanced Computing of MOE, Sun Yat-sen University , Guangzhou 510000, China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"School of Computer Science and Engineering, Sun Yat-sen University , Guangzhou 510000, China","institution_ids":["https://openalex.org/I157773358"]},{"raw_affiliation_string":"Key Laboratory of Machine Intelligence and Advanced Computing of MOE, Sun Yat-sen University, Guang-zhou 510000, China","institution_ids":["https://openalex.org/I157773358"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5032724151"],"corresponding_institution_ids":["https://openalex.org/I11701301","https://openalex.org/I4210102541","https://openalex.org/I4210128628"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":18.5487,"has_fulltext":false,"cited_by_count":186,"citation_normalized_percentile":{"value":0.99513646,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"38","issue":"1","first_page":"125","last_page":"132"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7830734252929688},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.662205159664154},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.5262928605079651},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.520308256149292},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5076102018356323},{"id":"https://openalex.org/keywords/residual","display_name":"Residual","score":0.4780728816986084},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.45902806520462036},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.43386223912239075},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3881853520870209},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.18002063035964966},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1379242241382599}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7830734252929688},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.662205159664154},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.5262928605079651},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.520308256149292},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5076102018356323},{"id":"https://openalex.org/C155512373","wikidata":"https://www.wikidata.org/wiki/Q287450","display_name":"Residual","level":2,"score":0.4780728816986084},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.45902806520462036},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.43386223912239075},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3881853520870209},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.18002063035964966},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1379242241382599},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btab643","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab643","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34498061","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34498061","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/408619","is_oa":false,"landing_page_url":"http://hdl.handle.net/10072/408619","pdf_url":null,"source":{"id":"https://openalex.org/S4306402548","display_name":"Griffith Research Online (Griffith University, Queensland, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I11701301","host_organization_name":"Griffith University","host_organization_lineage":["https://openalex.org/I11701301"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1121271761","display_name":null,"funder_award_id":"Program","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1477544716","display_name":null,"funder_award_id":"Guangdong","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2602136225","display_name":null,"funder_award_id":"2018B01","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2981938667","display_name":null,"funder_award_id":"Shenzhen","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3085993365","display_name":null,"funder_award_id":"(Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3866723802","display_name":null,"funder_award_id":"201703","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3931435871","display_name":null,"funder_award_id":"2020YFB0204803","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G5108781970","display_name":null,"funder_award_id":"61772566","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5939423041","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6069953956","display_name":null,"funder_award_id":"2018B0101","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6346021793","display_name":null,"funder_award_id":"2019B020228001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7142395142","display_name":null,"funder_award_id":"62041209","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7726157001","display_name":null,"funder_award_id":"Grant No.","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8208342437","display_name":null,"funder_award_id":"1 and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8412750340","display_name":null,"funder_award_id":"2017033","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8955107213","display_name":null,"funder_award_id":"Major","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G962820005","display_name":null,"funder_award_id":"S201101001","funder_id":"https://openalex.org/F4320331248","funder_display_name":"Shenzhen Bay Laboratory"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320331248","display_name":"Shenzhen Bay Laboratory","ror":"https://ror.org/00sdcjz77"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1829437510","https://openalex.org/W1966716734","https://openalex.org/W1967293793","https://openalex.org/W2001457899","https://openalex.org/W2008708467","https://openalex.org/W2009672036","https://openalex.org/W2017230497","https://openalex.org/W2041000185","https://openalex.org/W2045204781","https://openalex.org/W2051210555","https://openalex.org/W2055043387","https://openalex.org/W2056169996","https://openalex.org/W2076048958","https://openalex.org/W2104760790","https://openalex.org/W2108134720","https://openalex.org/W2130479394","https://openalex.org/W2141627824","https://openalex.org/W2151412657","https://openalex.org/W2155194485","https://openalex.org/W2158714788","https://openalex.org/W2162682281","https://openalex.org/W2166663852","https://openalex.org/W2557595285","https://openalex.org/W2618529956","https://openalex.org/W2722005050","https://openalex.org/W2754800853","https://openalex.org/W2808950571","https://openalex.org/W2944679105","https://openalex.org/W2955690154","https://openalex.org/W2971405760","https://openalex.org/W2984274952","https://openalex.org/W2991877021","https://openalex.org/W2992752586","https://openalex.org/W2998799485","https://openalex.org/W3009202743","https://openalex.org/W3013976849","https://openalex.org/W3080498684","https://openalex.org/W3129073614","https://openalex.org/W3140605903","https://openalex.org/W3177828909","https://openalex.org/W4252684946","https://openalex.org/W4295312788","https://openalex.org/W6652574002","https://openalex.org/W6766978945","https://openalex.org/W6798407072"],"related_works":["https://openalex.org/W2560215812","https://openalex.org/W2949601986","https://openalex.org/W4375867731","https://openalex.org/W2788972299","https://openalex.org/W4226493464","https://openalex.org/W3133861977","https://openalex.org/W2990636717","https://openalex.org/W2951211570","https://openalex.org/W3103566983","https://openalex.org/W4300237897"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":56},{"year":2024,"cited_by_count":55},{"year":2023,"cited_by_count":44},{"year":2022,"cited_by_count":21},{"year":2021,"cited_by_count":3}],"updated_date":"2026-03-29T08:15:47.926485","created_date":"2025-10-10T00:00:00"}
