{"id":"https://openalex.org/W3193996240","doi":"https://doi.org/10.1093/bioinformatics/btab608","title":"Multi-omics data integration by generative adversarial network","display_name":"Multi-omics data integration by generative adversarial network","publication_year":2021,"publication_date":"2021-08-18","ids":{"openalex":"https://openalex.org/W3193996240","doi":"https://doi.org/10.1093/bioinformatics/btab608","mag":"3193996240","pmid":"https://pubmed.ncbi.nlm.nih.gov/34415323"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab608","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab608","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10060730/pdf/btab608.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074491379","display_name":"Khandakar Tanvir Ahmed","orcid":null},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Khandakar Tanvir Ahmed","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079380128","display_name":"Jiao Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiao Sun","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000994867","display_name":"Sze Cheng","orcid":"https://orcid.org/0000-0002-0102-9812"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sze Cheng","raw_affiliation_strings":["Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Twin Cities , Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Twin Cities , Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010172507","display_name":"Jeongsik Yong","orcid":"https://orcid.org/0000-0002-2758-0450"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeongsik Yong","raw_affiliation_strings":["Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Twin Cities , Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Twin Cities , Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100441789","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0003-3605-9373"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Zhang","raw_affiliation_strings":["Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"Genomics and Bioinformatics Cluster, University of Central Florida , Orlando, FL 32816, USA","institution_ids":["https://openalex.org/I106165777"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5074491379"],"corresponding_institution_ids":["https://openalex.org/I106165777"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.636,"has_fulltext":true,"cited_by_count":88,"citation_normalized_percentile":{"value":0.96228577,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"38","issue":"1","first_page":"179","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9782999753952026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adversarial-system","display_name":"Adversarial system","score":0.7079905867576599},{"id":"https://openalex.org/keywords/generative-grammar","display_name":"Generative grammar","score":0.6945691704750061},{"id":"https://openalex.org/keywords/generative-adversarial-network","display_name":"Generative adversarial network","score":0.6856834888458252},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6819243431091309},{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.5216598510742188},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.45420002937316895},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42376959323883057},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.37305977940559387},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.36440861225128174},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3595086336135864},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.35873034596443176},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.22026365995407104},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.19446206092834473},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1722296178340912}],"concepts":[{"id":"https://openalex.org/C37736160","wikidata":"https://www.wikidata.org/wiki/Q1801315","display_name":"Adversarial system","level":2,"score":0.7079905867576599},{"id":"https://openalex.org/C39890363","wikidata":"https://www.wikidata.org/wiki/Q36108","display_name":"Generative grammar","level":2,"score":0.6945691704750061},{"id":"https://openalex.org/C2988773926","wikidata":"https://www.wikidata.org/wiki/Q25104379","display_name":"Generative adversarial network","level":3,"score":0.6856834888458252},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6819243431091309},{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.5216598510742188},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.45420002937316895},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42376959323883057},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.37305977940559387},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.36440861225128174},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3595086336135864},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35873034596443176},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.22026365995407104},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.19446206092834473},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1722296178340912}],"mesh":[{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btab608","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab608","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34415323","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34415323","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10060730","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10060730","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10060730/pdf/btab608.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10060730","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10060730","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10060730/pdf/btab608.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6200000047683716,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1500373947","display_name":null,"funder_award_id":"2R01GM113952-06","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G233321603","display_name":null,"funder_award_id":"1755761","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2654023646","display_name":null,"funder_award_id":"NSF-III1755761","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3611247453","display_name":null,"funder_award_id":"R01GM","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5921281487","display_name":null,"funder_award_id":"number","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6345853531","display_name":null,"funder_award_id":"unknown","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7008153868","display_name":null,"funder_award_id":"2R01GM113952","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8169943893","display_name":null,"funder_award_id":"DK097771","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G905787544","display_name":null,"funder_award_id":"R01GM113952","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3193996240.pdf","grobid_xml":"https://content.openalex.org/works/W3193996240.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1987219048","https://openalex.org/W2044702943","https://openalex.org/W2096283457","https://openalex.org/W2101234009","https://openalex.org/W2114843025","https://openalex.org/W2123696077","https://openalex.org/W2134629862","https://openalex.org/W2154149573","https://openalex.org/W2157076315","https://openalex.org/W2175370850","https://openalex.org/W2180481128","https://openalex.org/W2396849069","https://openalex.org/W2560367415","https://openalex.org/W2612122212","https://openalex.org/W2785329615","https://openalex.org/W2794416695","https://openalex.org/W2808845633","https://openalex.org/W2895736867","https://openalex.org/W2899335103","https://openalex.org/W2906107882","https://openalex.org/W2910993836","https://openalex.org/W2950878899","https://openalex.org/W2953285308","https://openalex.org/W2955502047","https://openalex.org/W2956963717","https://openalex.org/W2965512201","https://openalex.org/W3003192283","https://openalex.org/W3028304854","https://openalex.org/W3037216933","https://openalex.org/W3040723250","https://openalex.org/W3043427624","https://openalex.org/W3044522460","https://openalex.org/W3097349486","https://openalex.org/W3100788068","https://openalex.org/W3117393006","https://openalex.org/W3185131580","https://openalex.org/W4320013936","https://openalex.org/W6675354045"],"related_works":["https://openalex.org/W2888032422","https://openalex.org/W2996316059","https://openalex.org/W2924366642","https://openalex.org/W4385421777","https://openalex.org/W4392558563","https://openalex.org/W4377980832","https://openalex.org/W2897769091","https://openalex.org/W3159101980","https://openalex.org/W3173875945","https://openalex.org/W2845413374"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":22},{"year":2024,"cited_by_count":33},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":12}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}