{"id":"https://openalex.org/W3177750787","doi":"https://doi.org/10.1093/bioinformatics/btab295","title":"A novel constrained genetic algorithm-based Boolean network inference method from steady-state gene expression data","display_name":"A novel constrained genetic algorithm-based Boolean network inference method from steady-state gene expression data","publication_year":2021,"publication_date":"2021-04-24","ids":{"openalex":"https://openalex.org/W3177750787","doi":"https://doi.org/10.1093/bioinformatics/btab295","mag":"3177750787","pmid":"https://pubmed.ncbi.nlm.nih.gov/34252959"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab295","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab295","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i383/39620232/btab295.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i383/39620232/btab295.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088052580","display_name":"Hung-Cuong Trinh","orcid":"https://orcid.org/0000-0002-2172-8231"},"institutions":[{"id":"https://openalex.org/I141445968","display_name":"Ton Duc Thang University","ror":"https://ror.org/01drq0835","country_code":"VN","type":"education","lineage":["https://openalex.org/I141445968"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Hung-Cuong Trinh","raw_affiliation_strings":["Faculty of Information Technology, Ton Duc Thang University , Ho Chi Minh 758307, Vietnam"],"affiliations":[{"raw_affiliation_string":"Faculty of Information Technology, Ton Duc Thang University , Ho Chi Minh 758307, Vietnam","institution_ids":["https://openalex.org/I141445968"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088493382","display_name":"Yung\u2010Keun Kwon","orcid":"https://orcid.org/0000-0001-5879-8703"},"institutions":[{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Yung-Keun Kwon","raw_affiliation_strings":["Department of IT Convergence, University of Ulsan , Ulsan 680-749, Korea"],"affiliations":[{"raw_affiliation_string":"Department of IT Convergence, University of Ulsan , Ulsan 680-749, Korea","institution_ids":["https://openalex.org/I40542001"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088493382"],"corresponding_institution_ids":["https://openalex.org/I40542001"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":1.4641,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.82164437,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"37","issue":"Supplement_1","first_page":"i383","last_page":"i391"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7194170951843262},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7125819325447083},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.6975996494293213},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.6182831525802612},{"id":"https://openalex.org/keywords/boolean-network","display_name":"Boolean network","score":0.6182419061660767},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4911041259765625},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.45742475986480713},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35690969228744507},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.34053105115890503},{"id":"https://openalex.org/keywords/boolean-function","display_name":"Boolean function","score":0.2486581802368164},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2074553370475769},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.18125835061073303},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.17636996507644653},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12212654948234558},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08708396553993225}],"concepts":[{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7194170951843262},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7125819325447083},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.6975996494293213},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.6182831525802612},{"id":"https://openalex.org/C134444547","wikidata":"https://www.wikidata.org/wiki/Q585230","display_name":"Boolean network","level":3,"score":0.6182419061660767},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4911041259765625},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.45742475986480713},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35690969228744507},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.34053105115890503},{"id":"https://openalex.org/C187455244","wikidata":"https://www.wikidata.org/wiki/Q942353","display_name":"Boolean function","level":2,"score":0.2486581802368164},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2074553370475769},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18125835061073303},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.17636996507644653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12212654948234558},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08708396553993225},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btab295","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab295","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i383/39620232/btab295.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34252959","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34252959","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8275338","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8275338","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btab295","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab295","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i383/39620232/btab295.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals","score":0.46000000834465027}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3177750787.pdf","grobid_xml":"https://content.openalex.org/works/W3177750787.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W240029891","https://openalex.org/W1556472699","https://openalex.org/W1971224531","https://openalex.org/W1991980854","https://openalex.org/W1993418188","https://openalex.org/W2008620264","https://openalex.org/W2017641680","https://openalex.org/W2029338813","https://openalex.org/W2032630997","https://openalex.org/W2035104280","https://openalex.org/W2050559302","https://openalex.org/W2067265108","https://openalex.org/W2073903631","https://openalex.org/W2076513103","https://openalex.org/W2081034667","https://openalex.org/W2094558888","https://openalex.org/W2097263107","https://openalex.org/W2105129830","https://openalex.org/W2106945333","https://openalex.org/W2108020239","https://openalex.org/W2121365413","https://openalex.org/W2122718339","https://openalex.org/W2138922092","https://openalex.org/W2146264532","https://openalex.org/W2154835728","https://openalex.org/W2156435185","https://openalex.org/W2157611962","https://openalex.org/W2163296115","https://openalex.org/W2165556326","https://openalex.org/W2353453863","https://openalex.org/W2460857593","https://openalex.org/W2498761000","https://openalex.org/W2512979031","https://openalex.org/W2520902279","https://openalex.org/W2586478664","https://openalex.org/W2602620302","https://openalex.org/W2997831639","https://openalex.org/W3099289621","https://openalex.org/W4388252848"],"related_works":["https://openalex.org/W2381031055","https://openalex.org/W2366070815","https://openalex.org/W2996519767","https://openalex.org/W2330768201","https://openalex.org/W2950199998","https://openalex.org/W1422717320","https://openalex.org/W2794960257","https://openalex.org/W2560421304","https://openalex.org/W2108120899","https://openalex.org/W2128085946"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}