{"id":"https://openalex.org/W3181626680","doi":"https://doi.org/10.1093/bioinformatics/btab278","title":"Weakly supervised learning of RNA modifications from low-resolution epitranscriptome data","display_name":"Weakly supervised learning of RNA modifications from low-resolution epitranscriptome data","publication_year":2021,"publication_date":"2021-04-23","ids":{"openalex":"https://openalex.org/W3181626680","doi":"https://doi.org/10.1093/bioinformatics/btab278","mag":"3181626680","pmid":"https://pubmed.ncbi.nlm.nih.gov/34252943"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab278","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab278","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i222/39620164/btab278.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i222/39620164/btab278.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066912329","display_name":"Daiyun Huang","orcid":"https://orcid.org/0000-0002-3067-7165"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Daiyun Huang","raw_affiliation_strings":["Department of Biological Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","Department of Computer Science, University of Liverpool , Liverpool L69 7ZB, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Department of Computer Science, University of Liverpool , Liverpool L69 7ZB, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018527188","display_name":"Bowen Song","orcid":"https://orcid.org/0000-0002-8586-0573"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Bowen Song","raw_affiliation_strings":["Department of Mathematical Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool L69 7ZB, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool L69 7ZB, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017244898","display_name":"Jingjue Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingjue Wei","raw_affiliation_strings":["Department of Mathematical Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085156744","display_name":"Jionglong Su","orcid":"https://orcid.org/0000-0001-5360-6493"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jionglong Su","raw_affiliation_strings":["AI University Research Centre, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AI University Research Centre, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073606016","display_name":"Frans Coenen","orcid":"https://orcid.org/0000-0003-1026-6649"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Frans Coenen","raw_affiliation_strings":["Department of Computer Science, University of Liverpool , Liverpool L69 7ZB, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Liverpool , Liverpool L69 7ZB, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062986831","display_name":"Jia Meng","orcid":"https://orcid.org/0000-0003-3455-205X"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN","GB"],"is_corresponding":true,"raw_author_name":"Jia Meng","raw_affiliation_strings":["AI University Research Centre, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","Department of Biological Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool L69 7ZB, UK","Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK"],"raw_orcid":"https://orcid.org/0000-0003-3455-205X","affiliations":[{"raw_affiliation_string":"AI University Research Centre, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Department of Biological Sciences, Xi\u2019an Jiaotong-Liverpool University , Suzhou, Jiangsu 215123, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool L69 7ZB, UK","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK","institution_ids":["https://openalex.org/I146655781"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5062986831"],"corresponding_institution_ids":["https://openalex.org/I146655781","https://openalex.org/I69356397"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":2.2204,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.88885549,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"37","issue":"Supplement_1","first_page":"i222","last_page":"i230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9610000252723694,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9610000252723694,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.01899999938905239,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.6893303394317627},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6480796933174133},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5859623551368713},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.4948109984397888},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.43922722339630127},{"id":"https://openalex.org/keywords/nucleic-acid-structure","display_name":"Nucleic acid structure","score":0.43905553221702576},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.4390344023704529},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4152410626411438},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3753589391708374},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37014156579971313},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2544197738170624},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2341519296169281},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16059860587120056}],"concepts":[{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6893303394317627},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6480796933174133},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5859623551368713},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.4948109984397888},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.43922722339630127},{"id":"https://openalex.org/C126142528","wikidata":"https://www.wikidata.org/wiki/Q3771876","display_name":"Nucleic acid structure","level":4,"score":0.43905553221702576},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4390344023704529},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4152410626411438},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3753589391708374},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37014156579971313},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2544197738170624},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2341519296169281},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16059860587120056},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069553","descriptor_name":"Supervised Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btab278","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab278","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i222/39620164/btab278.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34252943","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34252943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8336446","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8336446","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btab278","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab278","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/Supplement_1/i222/39620164/btab278.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5709834030","display_name":null,"funder_award_id":"31671373","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3181626680.pdf","grobid_xml":"https://content.openalex.org/works/W3181626680.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W1019830208","https://openalex.org/W1496114027","https://openalex.org/W1787224781","https://openalex.org/W2009556149","https://openalex.org/W2028071319","https://openalex.org/W2034145535","https://openalex.org/W2037248153","https://openalex.org/W2054101905","https://openalex.org/W2166153887","https://openalex.org/W2269649163","https://openalex.org/W2271549028","https://openalex.org/W2287984595","https://openalex.org/W2345143513","https://openalex.org/W2345512687","https://openalex.org/W2345998082","https://openalex.org/W2397270125","https://openalex.org/W2560674852","https://openalex.org/W2566723880","https://openalex.org/W2594735672","https://openalex.org/W2746791238","https://openalex.org/W2885815722","https://openalex.org/W2900694973","https://openalex.org/W2901932654","https://openalex.org/W2912369228","https://openalex.org/W2915489297","https://openalex.org/W2940752764","https://openalex.org/W2949275670","https://openalex.org/W2962851944","https://openalex.org/W2965635599","https://openalex.org/W2971454256","https://openalex.org/W2972933339","https://openalex.org/W2988273873","https://openalex.org/W2997580108","https://openalex.org/W3000716014","https://openalex.org/W3001921560","https://openalex.org/W3002531371","https://openalex.org/W3010754381","https://openalex.org/W3014996649","https://openalex.org/W3015190397","https://openalex.org/W3017297943","https://openalex.org/W3034921317","https://openalex.org/W3035833199","https://openalex.org/W3039873626","https://openalex.org/W3043981686","https://openalex.org/W3081618492","https://openalex.org/W3098699793","https://openalex.org/W3108267036","https://openalex.org/W4244831782","https://openalex.org/W6685133223","https://openalex.org/W6758850757","https://openalex.org/W6772444045","https://openalex.org/W6781327601"],"related_works":["https://openalex.org/W1472344963","https://openalex.org/W3093937951","https://openalex.org/W2554722417","https://openalex.org/W2470187006","https://openalex.org/W2581348958","https://openalex.org/W2264054990","https://openalex.org/W2581888268","https://openalex.org/W2902683473","https://openalex.org/W1989561030","https://openalex.org/W2088051090"],"abstract_inverted_index":{"MOTIVATION:":[0],"Increasing":[1],"evidence":[2],"suggests":[3],"that":[4,153],"post-transcriptional":[5],"ribonucleic":[6],"acid":[7],"(RNA)":[8],"modifications":[9,46,83,122,172],"regulate":[10],"essential":[11,30],"biomolecular":[12],"functions":[13],"and":[14,94,108,159],"are":[15,154,190,199],"related":[16],"to":[17,102],"the":[18,33,74,114,162,167,182,187],"pathogenesis":[19],"of":[20,25,36,51,116,161,169],"various":[21],"diseases.":[22],"Precise":[23],"identification":[24],"RNA":[26,45,82,105,121,171],"modification":[27,106],"sites":[28],"is":[29],"for":[31,43,80,132,142,181],"understanding":[32],"regulatory":[34],"mechanisms":[35],"RNAs.":[37],"To":[38],"date,":[39],"many":[40],"computational":[41],"approaches":[42],"predicting":[44,81,120],"have":[47],"been":[48],"developed,":[49],"most":[50],"which":[52,138],"were":[53],"based":[54],"on":[55,97],"strong":[56],"supervision":[57],"enabled":[58],"by":[59],"base-resolution":[60],"epitranscriptome":[61,86],"data.":[62,125],"However,":[63],"high-resolution":[64],"data":[65,198],"may":[66],"not":[67],"be":[68],"available.":[69],"RESULTS:":[70],"We":[71],"propose":[72],"WeakRM,":[73],"first":[75],"weakly":[76],"supervised":[77],"learning":[78,130],"framework":[79],"from":[84,92,123],"low-resolution":[85,124],"datasets,":[87],"such":[88,135],"as":[89,136],"those":[90],"generated":[91],"acRIP-seq":[93],"hMeRIP-seq.":[95],"Evaluations":[96],"three":[98,103],"independent":[99],"datasets":[100,188],"(corresponding":[101],"different":[104],"types":[107],"their":[109],"respective":[110],"sequencing":[111],"technologies)":[112],"demonstrated":[113],"effectiveness":[115],"our":[117,149],"approach":[118,150],"in":[119],"WeakRM":[126,183],"outperformed":[127],"state-of-the-art":[128],"multi-instance":[129],"methods":[131],"genomic":[133],"sequences,":[134],"WSCNN,":[137],"was":[139],"originally":[140],"designed":[141],"transcription":[143],"factor":[144],"binding":[145],"site":[146],"prediction.":[147],"Additionally,":[148],"captured":[151],"motifs":[152],"consistent":[155],"with":[156,173,186],"existing":[157],"knowledge,":[158],"visualization":[160],"predicted":[163],"modification-containing":[164],"regions":[165],"unveiled":[166],"potentials":[168],"detecting":[170],"improved":[174],"resolution.":[175],"AVAILABILITY":[176],"IMPLEMENTATION:":[177],"The":[178],"source":[179],"code":[180],"algorithm,":[184],"along":[185],"used,":[189],"freely":[191],"accessible":[192],"at:":[193],"https://github.com/daiyun02211/WeakRM.":[194],"SUPPLEMENTARY":[195],"INFORMATION:":[196],"Supplementary":[197],"available":[200],"at":[201],"Bioinformatics":[202],"online.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}