{"id":"https://openalex.org/W3122907156","doi":"https://doi.org/10.1093/bioinformatics/btab044","title":"CancerEMC: frontline non-invasive cancer screening from circulating protein biomarkers and mutations in cell-free DNA","display_name":"CancerEMC: frontline non-invasive cancer screening from circulating protein biomarkers and mutations in cell-free DNA","publication_year":2021,"publication_date":"2021-01-20","ids":{"openalex":"https://openalex.org/W3122907156","doi":"https://doi.org/10.1093/bioinformatics/btab044","mag":"3122907156","pmid":"https://pubmed.ncbi.nlm.nih.gov/33515231"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab044","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab044","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/19/3319/40556807/btab044.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/37/19/3319/40556807/btab044.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029563650","display_name":"Saifur Rahaman","orcid":"https://orcid.org/0000-0001-7883-3596"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Saifur Rahaman","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong , Kowloon, Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong , Kowloon, Hong Kong SAR","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002127716","display_name":"Xiangtao Li","orcid":"https://orcid.org/0000-0001-9089-1799"},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangtao Li","raw_affiliation_strings":["School of Artificial Intelligence, Jilin University , Changchun, Jilin, China"],"affiliations":[{"raw_affiliation_string":"School of Artificial Intelligence, Jilin University , Changchun, Jilin, China","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100614702","display_name":"Jun Yu","orcid":"https://orcid.org/0000-0001-5008-2153"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210116924","display_name":"Chinese University of Hong Kong, Shenzhen","ror":"https://ror.org/02d5ks197","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633","https://openalex.org/I180726961","https://openalex.org/I4210116924"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Jun Yu","raw_affiliation_strings":["Institute of Digestive Diseases and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong Shenzhen Research Institute, The Chinese University of Hong Kong , Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"Institute of Digestive Diseases and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong Shenzhen Research Institute, The Chinese University of Hong Kong , Hong Kong SAR","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210116924"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030015771","display_name":"Ka\u2010Chun Wong","orcid":"https://orcid.org/0000-0001-6062-733X"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Ka-Chun Wong","raw_affiliation_strings":["Department of Computer Science, City University of Hong Kong , Kowloon, Hong Kong SAR"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, City University of Hong Kong , Kowloon, Hong Kong SAR","institution_ids":["https://openalex.org/I168719708"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030015771"],"corresponding_institution_ids":["https://openalex.org/I168719708"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.5249,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.55577135,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"37","issue":"19","first_page":"3319","last_page":"3327"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oversampling","display_name":"Oversampling","score":0.621492862701416},{"id":"https://openalex.org/keywords/cell-free-fetal-dna","display_name":"Cell-free fetal DNA","score":0.5212410092353821},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.515119731426239},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5063761472702026},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.40673863887786865},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23611676692962646},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.19187140464782715},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17805010080337524}],"concepts":[{"id":"https://openalex.org/C197323446","wikidata":"https://www.wikidata.org/wiki/Q331222","display_name":"Oversampling","level":3,"score":0.621492862701416},{"id":"https://openalex.org/C152110520","wikidata":"https://www.wikidata.org/wiki/Q14225730","display_name":"Cell-free fetal DNA","level":5,"score":0.5212410092353821},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.515119731426239},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5063761472702026},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40673863887786865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23611676692962646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19187140464782715},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17805010080337524},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.0},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0},{"id":"https://openalex.org/C2776257435","wikidata":"https://www.wikidata.org/wiki/Q1576430","display_name":"Bandwidth (computing)","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btab044","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab044","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/19/3319/40556807/btab044.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33515231","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33515231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btab044","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab044","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/19/3319/40556807/btab044.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1697431053","display_name":null,"funder_award_id":"CityU 11202219","funder_id":"https://openalex.org/F4320309893","funder_display_name":"City University of Hong Kong"},{"id":"https://openalex.org/G6784292314","display_name":null,"funder_award_id":"CityU 11203520","funder_id":"https://openalex.org/F4320309893","funder_display_name":"City University of Hong Kong"},{"id":"https://openalex.org/G8108313816","display_name":null,"funder_award_id":"32000464","funder_id":"https://openalex.org/F4320309893","funder_display_name":"City University of Hong Kong"}],"funders":[{"id":"https://openalex.org/F4320309893","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323291","display_name":"Food and Health Bureau","ror":"https://ror.org/03qh32912"},{"id":"https://openalex.org/F4320333998","display_name":"Shenzhen Research Institute, City University of Hong Kong","ror":"https://ror.org/00xc0ma20"},{"id":"https://openalex.org/F4320334123","display_name":"Hong Kong Institute for Data Science","ror":null},{"id":"https://openalex.org/F4320335055","display_name":"Health and Medical Research Fund","ror":"https://ror.org/03qh32912"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3122907156.pdf","grobid_xml":"https://content.openalex.org/works/W3122907156.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W85350352","https://openalex.org/W613690151","https://openalex.org/W888521604","https://openalex.org/W1965920802","https://openalex.org/W1967304777","https://openalex.org/W1985361918","https://openalex.org/W2006175681","https://openalex.org/W2023061736","https://openalex.org/W2026713007","https://openalex.org/W2028841256","https://openalex.org/W2051609814","https://openalex.org/W2054681463","https://openalex.org/W2057441785","https://openalex.org/W2058622049","https://openalex.org/W2059220039","https://openalex.org/W2072347219","https://openalex.org/W2081277484","https://openalex.org/W2084130689","https://openalex.org/W2096335059","https://openalex.org/W2104641188","https://openalex.org/W2104933073","https://openalex.org/W2106787323","https://openalex.org/W2107956883","https://openalex.org/W2109542348","https://openalex.org/W2111574971","https://openalex.org/W2133990480","https://openalex.org/W2141007997","https://openalex.org/W2148143831","https://openalex.org/W2171237493","https://openalex.org/W2498672755","https://openalex.org/W2570649392","https://openalex.org/W2583706707","https://openalex.org/W2598084316","https://openalex.org/W2608738563","https://openalex.org/W2734646423","https://openalex.org/W2736808963","https://openalex.org/W2747939174","https://openalex.org/W2751788109","https://openalex.org/W2783674487","https://openalex.org/W2791176983","https://openalex.org/W2886963239","https://openalex.org/W2888094747","https://openalex.org/W2889646458","https://openalex.org/W2914859268","https://openalex.org/W2917837889","https://openalex.org/W2942929308","https://openalex.org/W2947989913","https://openalex.org/W2959842928","https://openalex.org/W2961229668","https://openalex.org/W2965500016","https://openalex.org/W2980183989","https://openalex.org/W2984084835","https://openalex.org/W2985757832","https://openalex.org/W2990870977","https://openalex.org/W2991166240","https://openalex.org/W2992156287","https://openalex.org/W2998647770","https://openalex.org/W2999297310","https://openalex.org/W2999932323","https://openalex.org/W3021601205","https://openalex.org/W3033761014","https://openalex.org/W6675634716","https://openalex.org/W6766486916"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2766503024","https://openalex.org/W4206637278","https://openalex.org/W2781247653","https://openalex.org/W4386005305","https://openalex.org/W3082051559","https://openalex.org/W1682621979","https://openalex.org/W4386214543","https://openalex.org/W1969988626","https://openalex.org/W3173198409"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":2}],"updated_date":"2026-04-03T22:45:19.894376","created_date":"2025-10-10T00:00:00"}