{"id":"https://openalex.org/W3081478166","doi":"https://doi.org/10.1093/bioinformatics/btaa741","title":"Bipartite tight spectral clustering (BiTSC) algorithm for identifying conserved gene co-clusters in two species","display_name":"Bipartite tight spectral clustering (BiTSC) algorithm for identifying conserved gene co-clusters in two species","publication_year":2020,"publication_date":"2020-08-13","ids":{"openalex":"https://openalex.org/W3081478166","doi":"https://doi.org/10.1093/bioinformatics/btaa741","mag":"3081478166","pmid":"https://pubmed.ncbi.nlm.nih.gov/32814973"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa741","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa741","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/9/1225/41158119/btaa741.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/37/9/1225/41158119/btaa741.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006161904","display_name":"Yidan Eden Sun","orcid":"https://orcid.org/0000-0003-0727-7005"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yidan Eden Sun","raw_affiliation_strings":["University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA"],"affiliations":[{"raw_affiliation_string":"University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016668273","display_name":"Heather J. Zhou","orcid":"https://orcid.org/0000-0001-9869-4896"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather J Zhou","raw_affiliation_strings":["University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA"],"affiliations":[{"raw_affiliation_string":"University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045434495","display_name":"Jingyi Jessica Li","orcid":"https://orcid.org/0000-0002-9288-5648"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jingyi Jessica Li","raw_affiliation_strings":["University of California Department of Computational Medicine, , Los Angeles, CA 90095-1766, USA","University of California Department of Human Genetics, , Los Angeles, CA 90095-7088, USA","University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA"],"affiliations":[{"raw_affiliation_string":"University of California Department of Computational Medicine, , Los Angeles, CA 90095-1766, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California Department of Human Genetics, , Los Angeles, CA 90095-7088, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California Department of Statistics, , Los Angeles, CA 90095-1554, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045434495"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.3344,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.57588757,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"37","issue":"9","first_page":"1225","last_page":"1233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7553336024284363},{"id":"https://openalex.org/keywords/bipartite-graph","display_name":"Bipartite graph","score":0.5309236645698547},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5050793290138245},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.501457691192627},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4641965627670288},{"id":"https://openalex.org/keywords/gene-cluster","display_name":"Gene cluster","score":0.45529794692993164},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.44500917196273804},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4336734414100647},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.27510878443717957},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2369394600391388},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.22972887754440308},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.17973250150680542},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.12616392970085144}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7553336024284363},{"id":"https://openalex.org/C197657726","wikidata":"https://www.wikidata.org/wiki/Q174733","display_name":"Bipartite graph","level":3,"score":0.5309236645698547},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5050793290138245},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.501457691192627},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4641965627670288},{"id":"https://openalex.org/C36857842","wikidata":"https://www.wikidata.org/wiki/Q1501261","display_name":"Gene cluster","level":3,"score":0.45529794692993164},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44500917196273804},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4336734414100647},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27510878443717957},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2369394600391388},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.22972887754440308},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.17973250150680542},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.12616392970085144}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btaa741","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa741","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/9/1225/41158119/btaa741.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32814973","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32814973","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:escholarship.org:ark:/13030/qt0zk6839v","is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/0zk6839v","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, vol 37, iss 9","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8599197","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8599197","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btaa741","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa741","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/37/9/1225/41158119/btaa741.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","score":0.6800000071525574,"id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G2661276392","display_name":null,"funder_award_id":"DBI-1846216","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3105137680","display_name":"CAREER: Advancing the Bioinformatic Infrastructure and Methodology for Single-cell RNA Sequencing","funder_award_id":"1846216","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3611247453","display_name":null,"funder_award_id":"R01GM","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4358256470","display_name":null,"funder_award_id":"R01GM120507","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4359693134","display_name":null,"funder_award_id":"NIGMS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6256189390","display_name":"Development of a general classification framework under the Neyman-Pearson Paradigm, with biomedical and social applications","funder_award_id":"1613338","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7189626769","display_name":null,"funder_award_id":"1829071","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7945138641","display_name":null,"funder_award_id":"R01GM120507","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8204812584","display_name":null,"funder_award_id":"DMS-1613338","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8442901025","display_name":null,"funder_award_id":"DGE-1829071","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306799","display_name":"Pharmaceutical Research and Manufacturers of America Foundation","ror":"https://ror.org/01z88k350"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332502","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3081478166.pdf","grobid_xml":"https://content.openalex.org/works/W3081478166.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W229097380","https://openalex.org/W1488296747","https://openalex.org/W1548779692","https://openalex.org/W1686696692","https://openalex.org/W1963954507","https://openalex.org/W1966957642","https://openalex.org/W1981509058","https://openalex.org/W1987643017","https://openalex.org/W1990368529","https://openalex.org/W1990453950","https://openalex.org/W1998871699","https://openalex.org/W2000495354","https://openalex.org/W2034784092","https://openalex.org/W2048216066","https://openalex.org/W2056124433","https://openalex.org/W2074468058","https://openalex.org/W2088367672","https://openalex.org/W2098527037","https://openalex.org/W2103148270","https://openalex.org/W2105860794","https://openalex.org/W2107168093","https://openalex.org/W2113076747","https://openalex.org/W2119998616","https://openalex.org/W2131933020","https://openalex.org/W2133576408","https://openalex.org/W2135123683","https://openalex.org/W2137084536","https://openalex.org/W2137285541","https://openalex.org/W2140736261","https://openalex.org/W2145100181","https://openalex.org/W2149049580","https://openalex.org/W2154431984","https://openalex.org/W2155834877","https://openalex.org/W2161607603","https://openalex.org/W2162142896","https://openalex.org/W2165874743","https://openalex.org/W2169056504","https://openalex.org/W2170624222","https://openalex.org/W2211558999","https://openalex.org/W2428601085","https://openalex.org/W2477408078","https://openalex.org/W2528291562","https://openalex.org/W2612690371","https://openalex.org/W2773852483","https://openalex.org/W2900044275","https://openalex.org/W2962912239","https://openalex.org/W3103168877","https://openalex.org/W4229487902","https://openalex.org/W6608852248","https://openalex.org/W6734468469"],"related_works":["https://openalex.org/W183875134","https://openalex.org/W4225426244","https://openalex.org/W1547016179","https://openalex.org/W2029617325","https://openalex.org/W2909382709","https://openalex.org/W2802217527","https://openalex.org/W2548423198","https://openalex.org/W2071094417","https://openalex.org/W2016002476","https://openalex.org/W2943200843"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}