{"id":"https://openalex.org/W3042654233","doi":"https://doi.org/10.1093/bioinformatics/btaa478","title":"Privacy-preserving construction of generalized linear mixed model for biomedical computation","display_name":"Privacy-preserving construction of generalized linear mixed model for biomedical computation","publication_year":2020,"publication_date":"2020-05-04","ids":{"openalex":"https://openalex.org/W3042654233","doi":"https://doi.org/10.1093/bioinformatics/btaa478","mag":"3042654233","pmid":"https://pubmed.ncbi.nlm.nih.gov/32657380"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa478","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa478","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_1/i128/33488895/btaa478.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_1/i128/33488895/btaa478.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000660323","display_name":"Rui Zhu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rui Zhu","raw_affiliation_strings":["Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA"],"affiliations":[{"raw_affiliation_string":"Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073746065","display_name":"Chao Jiang","orcid":"https://orcid.org/0000-0002-0467-6177"},"institutions":[{"id":"https://openalex.org/I82497590","display_name":"Auburn University","ror":"https://ror.org/02v80fc35","country_code":"US","type":"education","lineage":["https://openalex.org/I82497590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chao Jiang","raw_affiliation_strings":["Department of Computer Science and Software Engineering, Auburn University , Auburn, AL 36849, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Software Engineering, Auburn University , Auburn, AL 36849, USA","institution_ids":["https://openalex.org/I82497590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100333221","display_name":"Xiaofeng Wang","orcid":"https://orcid.org/0000-0001-8695-5868"},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofeng Wang","raw_affiliation_strings":["Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA"],"affiliations":[{"raw_affiliation_string":"Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100375557","display_name":"Shuang Wang","orcid":"https://orcid.org/0000-0001-6420-983X"},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuang Wang","raw_affiliation_strings":["Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA"],"affiliations":[{"raw_affiliation_string":"Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101552472","display_name":"Hao Zheng","orcid":"https://orcid.org/0000-0002-1678-9478"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hao Zheng","raw_affiliation_strings":["Department of Bioinformatics, Hangzhou Nuowei Information Technology , Hangzhou 310053, China"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Hangzhou Nuowei Information Technology , Hangzhou 310053, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078007096","display_name":"Haixu Tang","orcid":"https://orcid.org/0000-0001-8963-8155"},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Haixu Tang","raw_affiliation_strings":["Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA"],"affiliations":[{"raw_affiliation_string":"Luddy School of Informatics, Computing, and Engineering, Indiana University , Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5078007096"],"corresponding_institution_ids":["https://openalex.org/I4210119109"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.0625,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.91573106,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"36","issue":"Supplement_1","first_page":"i128","last_page":"i135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10845","display_name":"Advanced Causal Inference Techniques","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generalized-linear-mixed-model","display_name":"Generalized linear mixed model","score":0.7719669342041016},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6528118252754211},{"id":"https://openalex.org/keywords/generalized-linear-model","display_name":"Generalized linear model","score":0.5401588082313538},{"id":"https://openalex.org/keywords/outcome","display_name":"Outcome (game theory)","score":0.5037142634391785},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.49127858877182007},{"id":"https://openalex.org/keywords/random-effects-model","display_name":"Random effects model","score":0.4891410171985626},{"id":"https://openalex.org/keywords/mixed-model","display_name":"Mixed model","score":0.45186808705329895},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.41313883662223816},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3929208815097809},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2961244285106659},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.20590618252754211},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1838798224925995},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09953871369361877}],"concepts":[{"id":"https://openalex.org/C153720581","wikidata":"https://www.wikidata.org/wiki/Q5532490","display_name":"Generalized linear mixed model","level":2,"score":0.7719669342041016},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6528118252754211},{"id":"https://openalex.org/C41587187","wikidata":"https://www.wikidata.org/wiki/Q1501882","display_name":"Generalized linear model","level":2,"score":0.5401588082313538},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.5037142634391785},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.49127858877182007},{"id":"https://openalex.org/C168743327","wikidata":"https://www.wikidata.org/wiki/Q1826427","display_name":"Random effects model","level":3,"score":0.4891410171985626},{"id":"https://openalex.org/C16012445","wikidata":"https://www.wikidata.org/wiki/Q1501135","display_name":"Mixed model","level":2,"score":0.45186808705329895},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.41313883662223816},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3929208815097809},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2961244285106659},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.20590618252754211},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1838798224925995},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09953871369361877},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018907","descriptor_name":"Privacy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018907","descriptor_name":"Privacy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018907","descriptor_name":"Privacy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaa478","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa478","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_1/i128/33488895/btaa478.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32657380","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32657380","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7355231","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7355231","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btaa478","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa478","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_1/i128/33488895/btaa478.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8906022773","display_name":null,"funder_award_id":"CNS-1838083","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309291","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3042654233.pdf","grobid_xml":"https://content.openalex.org/works/W3042654233.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1514587894","https://openalex.org/W1946622722","https://openalex.org/W1998712640","https://openalex.org/W2041467022","https://openalex.org/W2066669827","https://openalex.org/W2083384763","https://openalex.org/W2090692107","https://openalex.org/W2101365565","https://openalex.org/W2105369704","https://openalex.org/W2107482271","https://openalex.org/W2108207895","https://openalex.org/W2118788747","https://openalex.org/W2119167955","https://openalex.org/W2147604124","https://openalex.org/W2154611405","https://openalex.org/W2157440718","https://openalex.org/W2165766480","https://openalex.org/W2174203236","https://openalex.org/W2249520589","https://openalex.org/W2568218703","https://openalex.org/W2598240333","https://openalex.org/W2621320758","https://openalex.org/W2738534180","https://openalex.org/W2801958627","https://openalex.org/W2897095218","https://openalex.org/W2897368304","https://openalex.org/W2917029641","https://openalex.org/W4236786653","https://openalex.org/W4241091798"],"related_works":["https://openalex.org/W4239710992","https://openalex.org/W2356286374","https://openalex.org/W2895736713","https://openalex.org/W1551599973","https://openalex.org/W4307324678","https://openalex.org/W2082190293","https://openalex.org/W2021312236","https://openalex.org/W225107685","https://openalex.org/W2347384281","https://openalex.org/W2577604051"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}