{"id":"https://openalex.org/W3011946302","doi":"https://doi.org/10.1093/bioinformatics/btaa159","title":"SphereCon\u2014a method for precise estimation of residue relative solvent accessible area from limited structural information","display_name":"SphereCon\u2014a method for precise estimation of residue relative solvent accessible area from limited structural information","publication_year":2020,"publication_date":"2020-03-06","ids":{"openalex":"https://openalex.org/W3011946302","doi":"https://doi.org/10.1093/bioinformatics/btaa159","mag":"3011946302","pmid":"https://pubmed.ncbi.nlm.nih.gov/32154837"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa159","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/11/3372/33329090/btaa159.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/11/3372/33329090/btaa159.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012893089","display_name":"Alexander Gre\u00df","orcid":"https://orcid.org/0000-0001-9554-805X"},"institutions":[{"id":"https://openalex.org/I4210142777","display_name":"Helmholtz Institute for Pharmaceutical Research Saarland","ror":"https://ror.org/042dsac10","country_code":"DE","type":"government","lineage":["https://openalex.org/I1305996414","https://openalex.org/I4210124929","https://openalex.org/I4210142777"]},{"id":"https://openalex.org/I4210124929","display_name":"Helmholtz Centre for Infection Research","ror":"https://ror.org/03d0p2685","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I4210124929"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Alexander Gress","raw_affiliation_strings":["Department of Drug Bioinformatics , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbr\u00fccken 66123, Germany","Graduate School of Computer Science , Saarland University, Saarbr\u00fccken 66123, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Drug Bioinformatics , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbr\u00fccken 66123, Germany","institution_ids":["https://openalex.org/I4210142777","https://openalex.org/I4210124929"]},{"raw_affiliation_string":"Graduate School of Computer Science , Saarland University, Saarbr\u00fccken 66123, Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101632496","display_name":"Olga V. Kalinina","orcid":"https://orcid.org/0000-0002-9445-477X"},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]},{"id":"https://openalex.org/I4210142777","display_name":"Helmholtz Institute for Pharmaceutical Research Saarland","ror":"https://ror.org/042dsac10","country_code":"DE","type":"government","lineage":["https://openalex.org/I1305996414","https://openalex.org/I4210124929","https://openalex.org/I4210142777"]},{"id":"https://openalex.org/I4210124929","display_name":"Helmholtz Centre for Infection Research","ror":"https://ror.org/03d0p2685","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I4210124929"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Olga V Kalinina","raw_affiliation_strings":["Department of Drug Bioinformatics , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbr\u00fccken 66123, Germany","Medical Faculty , Saarland University, Homburg 66421, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Drug Bioinformatics , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus E8.1, Saarbr\u00fccken 66123, Germany","institution_ids":["https://openalex.org/I4210142777","https://openalex.org/I4210124929"]},{"raw_affiliation_string":"Medical Faculty , Saarland University, Homburg 66421, Germany","institution_ids":["https://openalex.org/I91712215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012893089"],"corresponding_institution_ids":["https://openalex.org/I4210124929","https://openalex.org/I4210142777","https://openalex.org/I91712215"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.2504,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.52869294,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"36","issue":"11","first_page":"3372","last_page":"3378"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/accessible-surface-area","display_name":"Accessible surface area","score":0.6955775618553162},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6115620732307434},{"id":"https://openalex.org/keywords/residue","display_name":"Residue (chemistry)","score":0.6042618751525879},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.5524777173995972},{"id":"https://openalex.org/keywords/solvent","display_name":"Solvent","score":0.5011403560638428},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.49813318252563477},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4660288989543915},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.46497249603271484},{"id":"https://openalex.org/keywords/intersection","display_name":"Intersection (aeronautics)","score":0.45395416021347046},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36217641830444336},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3274685740470886},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.26670143008232117},{"id":"https://openalex.org/keywords/computational-chemistry","display_name":"Computational chemistry","score":0.18243861198425293},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11404198408126831}],"concepts":[{"id":"https://openalex.org/C11072593","wikidata":"https://www.wikidata.org/wiki/Q3622068","display_name":"Accessible surface area","level":2,"score":0.6955775618553162},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6115620732307434},{"id":"https://openalex.org/C2781338088","wikidata":"https://www.wikidata.org/wiki/Q903495","display_name":"Residue (chemistry)","level":2,"score":0.6042618751525879},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.5524777173995972},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.5011403560638428},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.49813318252563477},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4660288989543915},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.46497249603271484},{"id":"https://openalex.org/C64543145","wikidata":"https://www.wikidata.org/wiki/Q162942","display_name":"Intersection (aeronautics)","level":2,"score":0.45395416021347046},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36217641830444336},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3274685740470886},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26670143008232117},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.18243861198425293},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11404198408126831},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaa159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa159","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/11/3372/33329090/btaa159.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32154837","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32154837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:repository.helmholtz-hzi.de:10033/622303","is_oa":true,"landing_page_url":"http://hdl.handle.net/10033/622303","pdf_url":null,"source":{"id":"https://openalex.org/S4377196474","display_name":"HZI (Helmholtz Centre for Infection Research)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210124929","host_organization_name":"Helmholtz Centre for Infection Research","host_organization_lineage":["https://openalex.org/I4210124929"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"36","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btaa159","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa159","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/11/3372/33329090/btaa159.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3011946302.pdf","grobid_xml":"https://content.openalex.org/works/W3011946302.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W1499450468","https://openalex.org/W1500350251","https://openalex.org/W1895528264","https://openalex.org/W1967058595","https://openalex.org/W1973316131","https://openalex.org/W1988075691","https://openalex.org/W2002052142","https://openalex.org/W2003859834","https://openalex.org/W2008708467","https://openalex.org/W2021217817","https://openalex.org/W2034126246","https://openalex.org/W2037070866","https://openalex.org/W2059067075","https://openalex.org/W2060107523","https://openalex.org/W2061042699","https://openalex.org/W2061241873","https://openalex.org/W2063031793","https://openalex.org/W2063274819","https://openalex.org/W2066507577","https://openalex.org/W2071615629","https://openalex.org/W2076834308","https://openalex.org/W2081288740","https://openalex.org/W2085277871","https://openalex.org/W2089685973","https://openalex.org/W2096413602","https://openalex.org/W2097270746","https://openalex.org/W2100908214","https://openalex.org/W2101220662","https://openalex.org/W2112702439","https://openalex.org/W2114340287","https://openalex.org/W2117950175","https://openalex.org/W2131474431","https://openalex.org/W2136799255","https://openalex.org/W2154106236","https://openalex.org/W2160784118","https://openalex.org/W2342838938","https://openalex.org/W2471276590","https://openalex.org/W2603587832","https://openalex.org/W2760622726","https://openalex.org/W2885015404","https://openalex.org/W2895146543","https://openalex.org/W2905446269","https://openalex.org/W2936064937","https://openalex.org/W2949867299","https://openalex.org/W2951621517","https://openalex.org/W2971003495","https://openalex.org/W3199799076","https://openalex.org/W4240185076","https://openalex.org/W4293003482","https://openalex.org/W6755124865"],"related_works":["https://openalex.org/W2348909947","https://openalex.org/W2011402521","https://openalex.org/W2067009594","https://openalex.org/W2088702338","https://openalex.org/W1974214659","https://openalex.org/W2164450010","https://openalex.org/W4205756281","https://openalex.org/W2123053169","https://openalex.org/W1987983260","https://openalex.org/W4367302235"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}