{"id":"https://openalex.org/W3119563737","doi":"https://doi.org/10.1093/bioinformatics/btaa1104","title":"<i>Machine-OlF-Action</i>: a unified framework for developing and interpreting machine-learning models for chemosensory research","display_name":"<i>Machine-OlF-Action</i>: a unified framework for developing and interpreting machine-learning models for chemosensory research","publication_year":2020,"publication_date":"2020-12-29","ids":{"openalex":"https://openalex.org/W3119563737","doi":"https://doi.org/10.1093/bioinformatics/btaa1104","mag":"3119563737","pmid":"https://pubmed.ncbi.nlm.nih.gov/33416866"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa1104","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa1104","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079895334","display_name":"Anku Gupta","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anku Gupta","raw_affiliation_strings":["Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023782353","display_name":"Mohit Choudhary","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohit Choudhary","raw_affiliation_strings":["Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033669171","display_name":"Sanjay Kumar Mohanty","orcid":"https://orcid.org/0000-0002-1375-2223"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjay Kumar Mohanty","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074985209","display_name":"Aayushi Mittal","orcid":"https://orcid.org/0000-0002-1973-8553"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Aayushi Mittal","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035333894","display_name":"Krishan Gupta","orcid":"https://orcid.org/0000-0002-3390-9494"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Krishan Gupta","raw_affiliation_strings":["Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007808467","display_name":"Aditya Arya","orcid":"https://orcid.org/0000-0002-9629-2532"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aditya Arya","raw_affiliation_strings":["Pathfinder Research and Training Foundation, 30/7 and 8, Knowledge Park III , Greater Noida, Uttar Pradesh 201308, India"],"raw_orcid":"https://orcid.org/0000-0002-9629-2532","affiliations":[{"raw_affiliation_string":"Pathfinder Research and Training Foundation, 30/7 and 8, Knowledge Park III , Greater Noida, Uttar Pradesh 201308, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073901722","display_name":"Suvendu Kumar","orcid":"https://orcid.org/0000-0002-4405-8402"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Suvendu Kumar","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007002748","display_name":"Nikhil Katyayan","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nikhil Katyayan","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064284191","display_name":"Nilesh Kumar Dixit","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nilesh Kumar Dixit","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028026030","display_name":"Siddhant Kalra","orcid":"https://orcid.org/0000-0003-2800-4559"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Siddhant Kalra","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042545682","display_name":"Manshi Goel","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manshi Goel","raw_affiliation_strings":["Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003239949","display_name":"Megha Sahni","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Megha Sahni","raw_affiliation_strings":["Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072811015","display_name":"Vrinda Singhal","orcid":null},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vrinda Singhal","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027124535","display_name":"Tripti Mishra","orcid":"https://orcid.org/0000-0003-1044-1603"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tripti Mishra","raw_affiliation_strings":["Pathfinder Research and Training Foundation, 30/7 and 8, Knowledge Park III , Greater Noida, Uttar Pradesh 201308, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathfinder Research and Training Foundation, 30/7 and 8, Knowledge Park III , Greater Noida, Uttar Pradesh 201308, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061015791","display_name":"Debarka Sengupta","orcid":"https://orcid.org/0000-0002-6353-5411"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["AU","IN"],"is_corresponding":true,"raw_author_name":"Debarka Sengupta","raw_affiliation_strings":["Centre for Artificial Intelligence, Indraprastha Institute of Information Technology , Okhla, Phase III, New Delhi 110020, India","Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","Institute of Health and Biomedical Innovation, Queensland University of Technology , Brisbane, QLD 4001, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Artificial Intelligence, Indraprastha Institute of Information Technology , Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252"]},{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]},{"raw_affiliation_string":"Institute of Health and Biomedical Innovation, Queensland University of Technology , Brisbane, QLD 4001, Australia","institution_ids":["https://openalex.org/I160993911"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060344855","display_name":"Gaurav Ahuja","orcid":"https://orcid.org/0000-0002-2837-9361"},"institutions":[{"id":"https://openalex.org/I119939252","display_name":"Indraprastha Institute of Information Technology Delhi","ror":"https://ror.org/03vfp4g33","country_code":"IN","type":"education","lineage":["https://openalex.org/I119939252"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Gaurav Ahuja","raw_affiliation_strings":["Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India"],"raw_orcid":"https://orcid.org/0000-0002-2837-9361","affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi), Okhla, Phase III, New Delhi 110020, India","institution_ids":["https://openalex.org/I119939252","https://openalex.org/I68891433"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5060344855","https://openalex.org/A5061015791"],"corresponding_institution_ids":["https://openalex.org/I119939252","https://openalex.org/I160993911","https://openalex.org/I68891433"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.8745,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.80653978,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"37","issue":"12","first_page":"1769","last_page":"1771"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.3215000033378601,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.3215000033378601,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.1670999974012375,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.163100004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7646491527557373},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.6982171535491943},{"id":"https://openalex.org/keywords/chemical-database","display_name":"Chemical database","score":0.6334729194641113},{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.6229775547981262},{"id":"https://openalex.org/keywords/cheminformatics","display_name":"Cheminformatics","score":0.6083422899246216},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5918082594871521},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.5894805192947388},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5706963539123535},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.4168117344379425},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.26036229729652405},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2186574935913086},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1171177327632904}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7646491527557373},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6982171535491943},{"id":"https://openalex.org/C203394866","wikidata":"https://www.wikidata.org/wiki/Q2881060","display_name":"Chemical database","level":2,"score":0.6334729194641113},{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.6229775547981262},{"id":"https://openalex.org/C68762167","wikidata":"https://www.wikidata.org/wiki/Q910164","display_name":"Cheminformatics","level":2,"score":0.6083422899246216},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5918082594871521},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.5894805192947388},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5706963539123535},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4168117344379425},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.26036229729652405},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2186574935913086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1171177327632904},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btaa1104","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa1104","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33416866","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33416866","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Quality Education","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/4"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319018","display_name":"Ministry of Science and Technology, Pakistan","ror":null},{"id":"https://openalex.org/F4320320020","display_name":"Inspire Foundation","ror":"https://ror.org/019s18q02"},{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320326272","display_name":"Department of Science and Technology, Philippines","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1991181258","https://openalex.org/W2080886752","https://openalex.org/W2140611297","https://openalex.org/W2156665896","https://openalex.org/W2159887157","https://openalex.org/W2282821441","https://openalex.org/W2340720529","https://openalex.org/W2756470092","https://openalex.org/W2767683865","https://openalex.org/W2791355014","https://openalex.org/W2798114923","https://openalex.org/W2803206732","https://openalex.org/W2808534407","https://openalex.org/W2898511110","https://openalex.org/W2914874661","https://openalex.org/W2937994991","https://openalex.org/W2946684615","https://openalex.org/W2956077997","https://openalex.org/W2982209755","https://openalex.org/W3003478287","https://openalex.org/W3086017582","https://openalex.org/W4244509809"],"related_works":["https://openalex.org/W2153037537","https://openalex.org/W2317928565","https://openalex.org/W3143892890","https://openalex.org/W2561309435","https://openalex.org/W2185159477","https://openalex.org/W2903373627","https://openalex.org/W2066666235","https://openalex.org/W158734140","https://openalex.org/W2988249053","https://openalex.org/W2127121938"],"abstract_inverted_index":{"SUMMARY:":[0],"Machine":[1],"Learning-based":[2],"techniques":[3,29],"are":[4,238],"emerging":[5],"as":[6],"state-of-the-art":[7,142],"methods":[8],"in":[9,54,153],"chemoinformatics":[10],"to":[11,36,92,128,231],"selectively,":[12],"effectively":[13],"and":[14,40,160,165,176,204,218,228],"speedily":[15],"identify":[16],"biologically":[17],"relevant":[18],"molecules":[19,130],"from":[20],"large":[21],"databases.":[22],"So":[23],"far,":[24],"a":[25,69,98,141],"multitude":[26],"of":[27,57,84,100,116,123,135,151,172],"such":[28],"have":[30],"been":[31],"proposed,":[32],"but":[33],"unfortunately":[34],"due":[35],"their":[37,47,89,136,173],"sparse":[38],"availability,":[39],"the":[41,55,85,133,149,169],"dependency":[42],"on":[43,132],"high-end":[44],"computational":[45,72],"literacy,":[46],"wider":[48],"adaptation":[49],"faces":[50],"challenges,":[51],"at":[52,210,222,240],"least":[53],"context":[56],"G-Protein":[58],"Coupled":[59],"Receptors":[60],"(GPCRs)-associated":[61],"chemosensory":[62],"research.":[63],"Here,":[64],"we":[65,181],"report":[66],"Machine-OlF-Action":[67],"(MOA),":[68],"user-friendly,":[70],"open-source":[71],"framework,":[73],"that":[74],"utilizes":[75],"user-supplied":[76,117],"SMILES":[77],"(simplified":[78],"molecular":[79],"input":[80],"line":[81],"entry":[82],"system)":[83],"chemicals,":[86],"along":[87],"with":[88],"activation":[90],"status,":[91],"synthesize":[93],"classification":[94],"models.":[95],"MOA":[96,111,124,152,198],"integrates":[97],"number":[99],"popular":[101],"chemical":[102,109,118,170,193],"databases":[103],"collectively":[104],"harboring":[105],"approximately":[106],"103":[107],"million":[108],"moieties.":[110],"also":[112],"facilitates":[113],"customized":[114],"screening":[115],"datasets.":[119],"A":[120],"key":[121],"feature":[122],"is":[125,199,220],"its":[126],"ability":[127],"embed":[129],"based":[131],"similarity":[134],"local":[137],"neighborhood,":[138],"by":[139,167],"utilizing":[140],"model":[143],"interpretability":[144],"framework":[145],"LIME.":[146],"We":[147],"demonstrate":[148],"utility":[150],"identifying":[154],"previously":[155],"unreported":[156],"agonists":[157,175],"for":[158,187,201],"human":[159],"mouse":[161],"olfactory":[162],"receptors":[163],"OR1A1":[164],"MOR174-9":[166],"leveraging":[168],"features":[171],"known":[174],"non-agonists.":[177],"In":[178],"summary,":[179],"here":[180],"develop":[182],"an":[183],"ML-powered":[184],"software":[185],"playground":[186],"performing":[188],"supervisory":[189],"learning":[190],"tasks":[191],"involving":[192],"compounds.":[194],"AVAILABILITY":[195],"AND":[196],"IMPLEMENTATION:":[197],"available":[200,221,239],"Windows,":[202],"Mac":[203],"Linux":[205],"operating":[206],"systems.":[207],"It's":[208],"accessible":[209],"(https://ahuja-lab.in/).":[211],"Source":[212],"code,":[213],"user":[214],"manual,":[215],"step-by-step":[216],"guide":[217],"support":[219],"GitHub":[223],"(https://github.com/the-ahuja-lab/Machine-Olf-Action).":[224],"For":[225],"results,":[226],"reproducibility":[227],"hyperparameters,":[229],"refer":[230],"Supplementary":[232,236],"Notes.":[233],"SUPPLEMENTARY":[234],"INFORMATION:":[235],"data":[237],"Bioinformatics":[241],"online.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2021-01-18T00:00:00"}