{"id":"https://openalex.org/W3006526394","doi":"https://doi.org/10.1093/bioinformatics/btaa099","title":"GeneSwitches: ordering gene expression and functional events in single-cell experiments","display_name":"GeneSwitches: ordering gene expression and functional events in single-cell experiments","publication_year":2020,"publication_date":"2020-02-10","ids":{"openalex":"https://openalex.org/W3006526394","doi":"https://doi.org/10.1093/bioinformatics/btaa099","mag":"3006526394","pmid":"https://pubmed.ncbi.nlm.nih.gov/32058565"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa099","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa099","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011542875","display_name":"Elaine Yiqun Cao","orcid":"https://orcid.org/0000-0003-0669-267X"},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Elaine Y Cao","raw_affiliation_strings":["Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore"],"affiliations":[{"raw_affiliation_string":"Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010565106","display_name":"John F. Ouyang","orcid":"https://orcid.org/0000-0002-1239-1577"},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"John F Ouyang","raw_affiliation_strings":["Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore"],"affiliations":[{"raw_affiliation_string":"Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071991185","display_name":"Owen J. L. Rackham","orcid":"https://orcid.org/0000-0002-4390-0872"},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Owen J L Rackham","raw_affiliation_strings":["Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore"],"affiliations":[{"raw_affiliation_string":"Program in Cardiovascular and Metabolic Disorders , Duke-NUS Medical School, 169857, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071991185"],"corresponding_institution_ids":["https://openalex.org/I4210126319"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.5876,"has_fulltext":false,"cited_by_count":128,"citation_normalized_percentile":{"value":0.94014228,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"36","issue":"10","first_page":"3273","last_page":"3275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9761999845504761,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.6120818853378296},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6031512022018433},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.5746088027954102},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5099517107009888},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4839370846748352},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.39327967166900635},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3839949667453766},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.13124457001686096}],"concepts":[{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.6120818853378296},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6031512022018433},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5746088027954102},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5099517107009888},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4839370846748352},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.39327967166900635},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3839949667453766},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.13124457001686096}],"mesh":[{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaa099","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa099","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32058565","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32058565","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:eprints.soton.ac.uk:447925","is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/447925/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7171666193","display_name":null,"funder_award_id":"NRF-CRP20-2017-0002","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"}],"funders":[{"id":"https://openalex.org/F4320320709","display_name":"National Research Foundation Singapore","ror":"https://ror.org/03cpyc314"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1984883254","https://openalex.org/W2562850749","https://openalex.org/W2747877289","https://openalex.org/W2895606183","https://openalex.org/W2947877009","https://openalex.org/W2951799803"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2392243736","https://openalex.org/W86652014","https://openalex.org/W2328518092","https://openalex.org/W2034625591","https://openalex.org/W2803323662","https://openalex.org/W3032874291","https://openalex.org/W2005057264","https://openalex.org/W2363156284","https://openalex.org/W2415025170"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":56},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":24},{"year":2021,"cited_by_count":4}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}