{"id":"https://openalex.org/W3000251091","doi":"https://doi.org/10.1093/bioinformatics/btaa026","title":"BAlaS: fast, interactive and accessible computational alanine-scanning using BudeAlaScan","display_name":"BAlaS: fast, interactive and accessible computational alanine-scanning using BudeAlaScan","publication_year":2020,"publication_date":"2020-01-09","ids":{"openalex":"https://openalex.org/W3000251091","doi":"https://doi.org/10.1093/bioinformatics/btaa026","mag":"3000251091","pmid":"https://pubmed.ncbi.nlm.nih.gov/31930404"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa026","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa026","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://research-information.bris.ac.uk/ws/files/223991365/BAlaS_2019_app_note_templated.pdf","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085979292","display_name":"Christopher W. Wood","orcid":"https://orcid.org/0000-0003-1243-3105"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Christopher W Wood","raw_affiliation_strings":["School of Biological Sciences , University of Edinburgh, Edinburgh EH9 3FF, UK"],"affiliations":[{"raw_affiliation_string":"School of Biological Sciences , University of Edinburgh, Edinburgh EH9 3FF, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031256252","display_name":"Amaurys \u00c1vila Ibarra","orcid":null},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amaurys A Ibarra","raw_affiliation_strings":["School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK"],"affiliations":[{"raw_affiliation_string":"School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054290443","display_name":"Gail J. Bartlett","orcid":"https://orcid.org/0000-0002-9932-2960"},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gail J Bartlett","raw_affiliation_strings":["School of Chemistry , University of Bristol, Bristol BS8 1TS, UK"],"affiliations":[{"raw_affiliation_string":"School of Chemistry , University of Bristol, Bristol BS8 1TS, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047034501","display_name":"Andrew J. Wilson","orcid":"https://orcid.org/0000-0001-9852-6366"},"institutions":[{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew J Wilson","raw_affiliation_strings":["Astbury Centre for Structural Molecular Biology , University of Leeds, Leeds LS2 9JT, UK","School of Chemistry"],"affiliations":[{"raw_affiliation_string":"Astbury Centre for Structural Molecular Biology , University of Leeds, Leeds LS2 9JT, UK","institution_ids":["https://openalex.org/I130828816"]},{"raw_affiliation_string":"School of Chemistry","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023900250","display_name":"Derek N. Woolfson","orcid":"https://orcid.org/0000-0002-0394-3202"},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Derek N Woolfson","raw_affiliation_strings":["BrisSynBio , University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK","School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK","School of Chemistry , University of Bristol, Bristol BS8 1TS, UK"],"affiliations":[{"raw_affiliation_string":"BrisSynBio , University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"School of Chemistry , University of Bristol, Bristol BS8 1TS, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001328340","display_name":"Richard B. Sessions","orcid":"https://orcid.org/0000-0003-0320-0895"},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Richard B Sessions","raw_affiliation_strings":["BrisSynBio , University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK","School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK"],"affiliations":[{"raw_affiliation_string":"BrisSynBio , University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"School of Biochemistry , University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5001328340","https://openalex.org/A5085979292"],"corresponding_institution_ids":["https://openalex.org/I36234482","https://openalex.org/I98677209"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":5.5141,"has_fulltext":true,"cited_by_count":77,"citation_normalized_percentile":{"value":0.96729977,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"36","issue":"9","first_page":"2917","last_page":"2919"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.9837999939918518,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.9837999939918518,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9825999736785889,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alanine-scanning","display_name":"Alanine scanning","score":0.9173498153686523},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7152684330940247},{"id":"https://openalex.org/keywords/license","display_name":"License","score":0.6087153553962708},{"id":"https://openalex.org/keywords/mit-license","display_name":"MIT License","score":0.5649793148040771},{"id":"https://openalex.org/keywords/alanine","display_name":"Alanine","score":0.5236432552337646},{"id":"https://openalex.org/keywords/mutagenesis","display_name":"Mutagenesis","score":0.4036467671394348},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.3227759003639221},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.2670862078666687},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.09236684441566467},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.08353137969970703}],"concepts":[{"id":"https://openalex.org/C2780227090","wikidata":"https://www.wikidata.org/wiki/Q2636892","display_name":"Alanine scanning","level":5,"score":0.9173498153686523},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7152684330940247},{"id":"https://openalex.org/C2780560020","wikidata":"https://www.wikidata.org/wiki/Q79719","display_name":"License","level":2,"score":0.6087153553962708},{"id":"https://openalex.org/C174183944","wikidata":"https://www.wikidata.org/wiki/Q334661","display_name":"MIT License","level":3,"score":0.5649793148040771},{"id":"https://openalex.org/C2779856020","wikidata":"https://www.wikidata.org/wiki/Q218642","display_name":"Alanine","level":3,"score":0.5236432552337646},{"id":"https://openalex.org/C16318435","wikidata":"https://www.wikidata.org/wiki/Q149299","display_name":"Mutagenesis","level":4,"score":0.4036467671394348},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3227759003639221},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.2670862078666687},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09236684441566467},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.08353137969970703},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000409","descriptor_name":"Alanine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000409","descriptor_name":"Alanine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000409","descriptor_name":"Alanine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000409","descriptor_name":"Alanine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btaa026","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa026","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31930404","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31930404","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:eprints.whiterose.ac.uk:156028","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/d7177090-08ca-4246-b97a-d38c217ee768","is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/d7177090-08ca-4246-b97a-d38c217ee768","pdf_url":"https://research-information.bris.ac.uk/ws/files/223991365/BAlaS_2019_app_note_templated.pdf","source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"pmh:oai:research-information.bris.ac.uk:publications/d7177090-08ca-4246-b97a-d38c217ee768","is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/d7177090-08ca-4246-b97a-d38c217ee768","pdf_url":"https://research-information.bris.ac.uk/ws/files/223991365/BAlaS_2019_app_note_templated.pdf","source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1015763213","display_name":null,"funder_award_id":"BB/L01386X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G1361938442","display_name":null,"funder_award_id":"Fellowship","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G1934935867","display_name":null,"funder_award_id":"Engineering and Physical Sciences R","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2055197655","display_name":null,"funder_award_id":"EP/N013573","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2669307404","display_name":null,"funder_award_id":"EP/N013573/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G2859517694","display_name":null,"funder_award_id":"BB/R00661X/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4145670801","display_name":null,"funder_award_id":"EP/S003002/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5933559460","display_name":"Development and experimental validation of a deep-learning based pipeline for user-centric protein design.","funder_award_id":"EP/S003002/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8452545418","display_name":null,"funder_award_id":"unknown","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8834797334","display_name":"Integrated computational and synthetic tools to drive the discovery of orthosteric protein-protein interaction inhibitors","funder_award_id":"EP/N013573/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320338335","display_name":"H2020 European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3000251091.pdf","grobid_xml":"https://content.openalex.org/works/W3000251091.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1998645872","https://openalex.org/W1999390565","https://openalex.org/W2010067768","https://openalex.org/W2023490488","https://openalex.org/W2042655455","https://openalex.org/W2058527555","https://openalex.org/W2067712920","https://openalex.org/W2117541321","https://openalex.org/W2155906069","https://openalex.org/W2172242534","https://openalex.org/W2475308546","https://openalex.org/W2621783632","https://openalex.org/W2791454012","https://openalex.org/W2973588605","https://openalex.org/W6767848864"],"related_works":["https://openalex.org/W2912839287","https://openalex.org/W4236187932","https://openalex.org/W2036021480","https://openalex.org/W1989527063","https://openalex.org/W3201765258","https://openalex.org/W955763280","https://openalex.org/W2042655455","https://openalex.org/W3094674094","https://openalex.org/W2082874149","https://openalex.org/W2618513029"],"abstract_inverted_index":{"BAlaS":[0],"works":[1],"on":[2,27],"all":[3],"modern":[4],"browsers":[5],"and":[6,24],"is":[7,16,25],"available":[8,26],"through":[9],"the":[10],"following":[11],"website:":[12],"https://balas.app.":[13],"The":[14],"project":[15],"open":[17],"source,":[18],"distributed":[19],"using":[20],"an":[21],"MIT":[22],"license":[23],"GitHub":[28],"(https://github.com/wells-wood-research/balas).":[29]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}