{"id":"https://openalex.org/W3003753408","doi":"https://doi.org/10.1093/bib/bbz170","title":"Deep learning-based clustering approaches for bioinformatics","display_name":"Deep learning-based clustering approaches for bioinformatics","publication_year":2019,"publication_date":"2019-12-17","ids":{"openalex":"https://openalex.org/W3003753408","doi":"https://doi.org/10.1093/bib/bbz170","mag":"3003753408","pmid":"https://pubmed.ncbi.nlm.nih.gov/32008043"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbz170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbz170","pdf_url":"https://academic.oup.com/bib/article-pdf/22/1/393/35934885/bbz170.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bib/article-pdf/22/1/393/35934885/bbz170.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114549797","display_name":"Md. Rezaul Karim","orcid":"https://orcid.org/0000-0001-6804-9183"},"institutions":[{"id":"https://openalex.org/I4210110507","display_name":"Fraunhofer Institute for Applied Information Technology","ror":"https://ror.org/01ak24c12","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210110507","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Md Rezaul Karim","raw_affiliation_strings":["Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","institution_ids":["https://openalex.org/I4210110507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067635650","display_name":"Oya Beyan","orcid":"https://orcid.org/0000-0001-7611-3501"},"institutions":[{"id":"https://openalex.org/I4210110507","display_name":"Fraunhofer Institute for Applied Information Technology","ror":"https://ror.org/01ak24c12","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210110507","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oya Beyan","raw_affiliation_strings":["Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","Information Systems and Databases, RWTH Aachen University, Aachen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","institution_ids":["https://openalex.org/I4210110507"]},{"raw_affiliation_string":"Information Systems and Databases, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034664449","display_name":"Achille Zappa","orcid":"https://orcid.org/0000-0003-4040-9620"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Achille Zappa","raw_affiliation_strings":["Insight Centre for Data Analytics, National University of Ireland Galway, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insight Centre for Data Analytics, National University of Ireland Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057250270","display_name":"Ivan G. Costa","orcid":"https://orcid.org/0000-0003-2890-8697"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ivan G Costa","raw_affiliation_strings":["Institute for Computational Genomics, RWTH Aachen University Medical School, Aachen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Computational Genomics, RWTH Aachen University Medical School, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006224704","display_name":"Dietrich Rebholz\u2010Schuhmann","orcid":"https://orcid.org/0000-0002-1018-0370"},"institutions":[{"id":"https://openalex.org/I4210112663","display_name":"ZB MED - Information Centre for Life Sciences","ror":"https://ror.org/0259fwx54","country_code":"DE","type":"archive","lineage":["https://openalex.org/I4210112663"]},{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dietrich Rebholz-Schuhmann","raw_affiliation_strings":["German National Library of Medicine, University of Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German National Library of Medicine, University of Cologne, Germany","institution_ids":["https://openalex.org/I4210112663","https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041317183","display_name":"Michael Cochez","orcid":"https://orcid.org/0000-0001-5726-4638"},"institutions":[{"id":"https://openalex.org/I4210110507","display_name":"Fraunhofer Institute for Applied Information Technology","ror":"https://ror.org/01ak24c12","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210110507","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["DE","NL"],"is_corresponding":false,"raw_author_name":"Michael Cochez","raw_affiliation_strings":["Department of Computer Science, Vrije Univeriteit Amsterdam, The Netherlands","Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Vrije Univeriteit Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I865915315"]},{"raw_affiliation_string":"Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","institution_ids":["https://openalex.org/I4210110507"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071104283","display_name":"Stefan Decker","orcid":"https://orcid.org/0000-0001-6324-7164"},"institutions":[{"id":"https://openalex.org/I4210110507","display_name":"Fraunhofer Institute for Applied Information Technology","ror":"https://ror.org/01ak24c12","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210110507","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Decker","raw_affiliation_strings":["Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","Information Systems and Databases, RWTH Aachen University, Aachen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Applied Information Technology FIT, Schloss Birlinghoven, Sankt Augustin, Germany","institution_ids":["https://openalex.org/I4210110507"]},{"raw_affiliation_string":"Information Systems and Databases, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5114549797"],"corresponding_institution_ids":["https://openalex.org/I4210110507"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":8.7185,"has_fulltext":false,"cited_by_count":302,"citation_normalized_percentile":{"value":0.98566713,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"1","first_page":"393","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.8966008424758911},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7326327562332153},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.615922212600708},{"id":"https://openalex.org/keywords/feature-learning","display_name":"Feature learning","score":0.53718101978302},{"id":"https://openalex.org/keywords/clustering-high-dimensional-data","display_name":"Clustering high-dimensional data","score":0.5317881107330322},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5252637267112732},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5002932548522949},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.454730361700058},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4403468072414398},{"id":"https://openalex.org/keywords/correlation-clustering","display_name":"Correlation clustering","score":0.4130290150642395}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.8966008424758911},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7326327562332153},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.615922212600708},{"id":"https://openalex.org/C59404180","wikidata":"https://www.wikidata.org/wiki/Q17013334","display_name":"Feature learning","level":2,"score":0.53718101978302},{"id":"https://openalex.org/C184509293","wikidata":"https://www.wikidata.org/wiki/Q5136711","display_name":"Clustering high-dimensional data","level":3,"score":0.5317881107330322},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5252637267112732},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5002932548522949},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.454730361700058},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4403468072414398},{"id":"https://openalex.org/C94641424","wikidata":"https://www.wikidata.org/wiki/Q5172845","display_name":"Correlation clustering","level":3,"score":0.4130290150642395},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1093/bib/bbz170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbz170","pdf_url":"https://academic.oup.com/bib/article-pdf/22/1/393/35934885/bbz170.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32008043","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32008043","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:research.vu.nl:openaire/d129e6b8-001d-4211-8776-b235344e928e","is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/d129e6b8-001d-4211-8776-b235344e928e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Karim, M R, Beyan, O, Zappa, A, Costa, I G, Rebholz-Schuhmann, D, Cochez, M & Decker, S 2021, 'Deep learning-based clustering approaches for bioinformatics', Briefings in bioinformatics, vol. 22, no. 1, pp. 393-415. https://doi.org/10.1093/bib/bbz170","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:europepmc.org:6746397","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7820885","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:fraunhofer.de:N-637433","is_oa":true,"landing_page_url":"http://publica.fraunhofer.de/documents/N-637433.html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400801","display_name":"Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fraunhofer FIT","raw_type":"Journal Article"},{"id":"pmh:oai:null:publica/269064","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/269064","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7820885","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7820885","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},{"id":"pmh:oai:research.vu.nl:openaire_cris_publications/d129e6b8-001d-4211-8776-b235344e928e","is_oa":true,"landing_page_url":"https://hdl.handle.net/1871.1/d129e6b8-001d-4211-8776-b235344e928e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Karim, M R, Beyan, O, Zappa, A, Costa, I G, Rebholz-Schuhmann, D, Cochez, M & Decker, S 2021, 'Deep learning-based clustering approaches for bioinformatics', Briefings in bioinformatics, vol. 22, no. 1, pp. 393-415. https://doi.org/10.1093/bib/bbz170","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"doi:10.18154/rwth-conv-243764","is_oa":true,"landing_page_url":"https://doi.org/10.18154/rwth-conv-243764","pdf_url":null,"source":{"id":"https://openalex.org/S4306401033","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1093/bib/bbz170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbz170","pdf_url":"https://academic.oup.com/bib/article-pdf/22/1/393/35934885/bbz170.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309480","display_name":"Nvidia","ror":"https://ror.org/03jdj4y14"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3003753408.pdf","grobid_xml":"https://content.openalex.org/works/W3003753408.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W1540089290","https://openalex.org/W1594924988","https://openalex.org/W1982621401","https://openalex.org/W2025768430","https://openalex.org/W2029906306","https://openalex.org/W2033403400","https://openalex.org/W2038706020","https://openalex.org/W2046079134","https://openalex.org/W2054274648","https://openalex.org/W2071949631","https://openalex.org/W2089468765","https://openalex.org/W2095705004","https://openalex.org/W2096759677","https://openalex.org/W2098123302","https://openalex.org/W2116435618","https://openalex.org/W2125310307","https://openalex.org/W2125836114","https://openalex.org/W2131994307","https://openalex.org/W2132037657","https://openalex.org/W2140736261","https://openalex.org/W2141012957","https://openalex.org/W2146646206","https://openalex.org/W2150926065","https://openalex.org/W2158485828","https://openalex.org/W2160938378","https://openalex.org/W2162833336","https://openalex.org/W2168029744","https://openalex.org/W2170584976","https://openalex.org/W2187089797","https://openalex.org/W2205138079","https://openalex.org/W2222512263","https://openalex.org/W2277663659","https://openalex.org/W2311607323","https://openalex.org/W2551604710","https://openalex.org/W2559479590","https://openalex.org/W2559655401","https://openalex.org/W2576353028","https://openalex.org/W2603986758","https://openalex.org/W2607075141","https://openalex.org/W2608862709","https://openalex.org/W2612526924","https://openalex.org/W2618735189","https://openalex.org/W2740411785","https://openalex.org/W2749535755","https://openalex.org/W2750867444","https://openalex.org/W2765741717","https://openalex.org/W2779692282","https://openalex.org/W2784962210","https://openalex.org/W2787801451","https://openalex.org/W2798859316","https://openalex.org/W2806534560","https://openalex.org/W2884851420","https://openalex.org/W2885824038","https://openalex.org/W2896457183","https://openalex.org/W2934474159","https://openalex.org/W2949241335","https://openalex.org/W2951381561","https://openalex.org/W2962369866","https://openalex.org/W2963166639","https://openalex.org/W2964118618","https://openalex.org/W2972392269","https://openalex.org/W2974062192","https://openalex.org/W2991530390","https://openalex.org/W2994156981","https://openalex.org/W2999905431","https://openalex.org/W3000157488","https://openalex.org/W3014321973","https://openalex.org/W3101749733","https://openalex.org/W3105265400","https://openalex.org/W3123831349","https://openalex.org/W3148043736","https://openalex.org/W4206174637","https://openalex.org/W4233635718","https://openalex.org/W4235169531","https://openalex.org/W4235792399","https://openalex.org/W4236965008","https://openalex.org/W4285719527","https://openalex.org/W4293568373","https://openalex.org/W4299445015","https://openalex.org/W6604426834","https://openalex.org/W6631235637","https://openalex.org/W6634568282","https://openalex.org/W6674330103","https://openalex.org/W6675122517","https://openalex.org/W6677326919","https://openalex.org/W6678288065","https://openalex.org/W6678914141","https://openalex.org/W6679117402","https://openalex.org/W6680970901","https://openalex.org/W6683488591","https://openalex.org/W6684050148","https://openalex.org/W6684578312","https://openalex.org/W6685380521","https://openalex.org/W6687888912","https://openalex.org/W6698064614","https://openalex.org/W6703008202","https://openalex.org/W6718140377","https://openalex.org/W6726186668","https://openalex.org/W6729669173","https://openalex.org/W6732902298","https://openalex.org/W6747233776","https://openalex.org/W6751923991","https://openalex.org/W6753211707","https://openalex.org/W6755207826","https://openalex.org/W6763093027","https://openalex.org/W6765939562","https://openalex.org/W6770825957","https://openalex.org/W6780248173","https://openalex.org/W7016021835"],"related_works":["https://openalex.org/W2111119584","https://openalex.org/W3186815950","https://openalex.org/W3080491161","https://openalex.org/W2040929534","https://openalex.org/W3107909692","https://openalex.org/W3088133960","https://openalex.org/W2311450085","https://openalex.org/W2590034888","https://openalex.org/W2371010743","https://openalex.org/W4292621762"],"abstract_inverted_index":{"Clustering":[0],"is":[1,35,119],"central":[2],"to":[3,37,142,156,180,243,248],"many":[4],"data-driven":[5],"bioinformatics":[6,185,212,251],"research":[7,252],"and":[8,21,31,70,82,89,102,111,205,219,227,235],"serves":[9],"a":[10,146,151,237],"powerful":[11],"computational":[12],"method.":[13],"In":[14,96,160],"particular,":[15],"clustering":[16,34,48,75,106,118,158,197,202],"helps":[17],"at":[18],"analyzing":[19],"unstructured":[20],"high-dimensional":[22,147],"data":[23,127,148],"in":[24,43,59,91,190],"the":[25,44,55,60,115,124,132,192,228],"form":[26],"of":[27,49,68,117,126,195],"sequences,":[28],"expressions,":[29],"texts":[30],"images.":[32],"Further,":[33,187],"used":[36,90],"gain":[38],"insights":[39,53,234],"into":[40,150],"biological":[41],"processes":[42],"genomics":[45,218],"level,":[46],"e.g.":[47],"gene":[50,63,72],"expressions":[51],"provides":[52],"on":[54,123,131,174,210],"natural":[56],"structure":[57],"inherent":[58],"data,":[61],"understanding":[62,71],"functions,":[64],"cellular":[65],"processes,":[66],"subtypes":[67],"cells":[69],"regulations.":[73],"Subsequently,":[74],"approaches,":[76],"including":[77,215],"hierarchical,":[78],"centroid-based,":[79],"distribution-based,":[80],"density-based":[81],"self-organizing":[83],"maps,":[84],"have":[85,107],"long":[86],"been":[87,109],"studied":[88],"classical":[92],"machine":[93],"learning":[94,99,104],"settings.":[95],"contrast,":[97],"deep":[98,135],"(DL)-based":[100],"representation":[101,175],"feature":[103,153],"for":[105,168,184,240],"not":[108,120],"reviewed":[110],"employed":[112],"extensively.":[113],"Since":[114],"quality":[116,203],"only":[121],"dependent":[122],"distribution":[125],"points":[128],"but":[129],"also":[130],"learned":[133],"representation,":[134],"neural":[136],"networks":[137],"can":[138],"be":[139,181],"effective":[140],"means":[141],"transform":[143],"mappings":[144],"from":[145],"space":[149],"lower-dimensional":[152],"space,":[154],"leading":[155],"improved":[157],"results.":[159],"this":[161,225],"paper,":[162],"we":[163,178,188],"review":[164,226],"state-of-the-art":[165],"DL-based":[166,196,208,245],"approaches":[167,209],"cluster":[169],"analysis":[170],"that":[171],"are":[172],"based":[173],"learning,":[176],"which":[177],"hope":[179],"useful,":[182],"particularly":[183],"research.":[186],"explore":[189],"detail":[191],"training":[193],"procedures":[194],"algorithms,":[198],"point":[199,239],"out":[200],"different":[201],"metrics":[204],"evaluate":[206],"several":[207],"three":[211],"use":[213],"cases,":[214],"bioimaging,":[216],"cancer":[217],"biomedical":[220],"text":[221],"mining.":[222],"We":[223],"believe":[224],"evaluation":[229],"results":[230],"will":[231],"provide":[232],"valuable":[233],"serve":[236],"starting":[238],"researchers":[241],"wanting":[242],"apply":[244],"unsupervised":[246],"methods":[247],"solve":[249],"emerging":[250],"problems.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":44},{"year":2024,"cited_by_count":79},{"year":2023,"cited_by_count":62},{"year":2022,"cited_by_count":50},{"year":2021,"cited_by_count":39},{"year":2020,"cited_by_count":13}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2020-02-07T00:00:00"}