{"id":"https://openalex.org/W3007629644","doi":"https://doi.org/10.1093/bib/bbz167","title":"Cooperative driver pathway discovery via fusion of multi-relational data of genes, miRNAs and pathways","display_name":"Cooperative driver pathway discovery via fusion of multi-relational data of genes, miRNAs and pathways","publication_year":2019,"publication_date":"2019-12-06","ids":{"openalex":"https://openalex.org/W3007629644","doi":"https://doi.org/10.1093/bib/bbz167","mag":"3007629644","pmid":"https://pubmed.ncbi.nlm.nih.gov/32103253"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbz167","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbz167","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100384767","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0002-5890-0365"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I97750245","display_name":"Software (Spain)","ror":"https://ror.org/02ethns06","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210087817","https://openalex.org/I97750245"]}],"countries":["CN","ES"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Professor of the School of Software, Shandong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor of the School of Software, Shandong University","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I97750245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101501447","display_name":"Ziying Yang","orcid":"https://orcid.org/0000-0002-0370-958X"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I97750245","display_name":"Software (Spain)","ror":"https://ror.org/02ethns06","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210087817","https://openalex.org/I97750245"]}],"countries":["CN","ES"],"is_corresponding":false,"raw_author_name":"Ziying Yang","raw_affiliation_strings":["Professor of the School of Software, Shandong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor of the School of Software, Shandong University","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I97750245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090148962","display_name":"Carlotta Domeniconi","orcid":"https://orcid.org/0000-0003-2140-9596"},"institutions":[{"id":"https://openalex.org/I162714631","display_name":"George Mason University","ror":"https://ror.org/02jqj7156","country_code":"US","type":"education","lineage":["https://openalex.org/I162714631"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlotta Domeniconi","raw_affiliation_strings":["Department of Computer Science, George Mason University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Mason University","institution_ids":["https://openalex.org/I162714631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000755750","display_name":"Xiangliang Zhang","orcid":"https://orcid.org/0000-0002-3574-5665"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Xiangliang Zhang","raw_affiliation_strings":["Computational Bioscience Research Center (CBRC), Computer Science, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology, SA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Bioscience Research Center (CBRC), Computer Science, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology, SA","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027082940","display_name":"Guoxian Yu","orcid":"https://orcid.org/0000-0002-1667-6705"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210091018","display_name":"Bioscience Research","ror":"https://ror.org/00bsjtn43","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210091018"]},{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]},{"id":"https://openalex.org/I97750245","display_name":"Software (Spain)","ror":"https://ror.org/02ethns06","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210087817","https://openalex.org/I97750245"]}],"countries":["CN","ES","SA","US"],"is_corresponding":true,"raw_author_name":"Guoxian Yu","raw_affiliation_strings":["Computational Bioscience Research Center (CBRC), Computer Science, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology, SA","Professor of the School of Software, Shandong University and Computational Bioscience Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Bioscience Research Center (CBRC), Computer Science, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology, SA","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"Professor of the School of Software, Shandong University and Computational Bioscience Research Center","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210091018","https://openalex.org/I97750245"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5027082940"],"corresponding_institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210091018","https://openalex.org/I71920554","https://openalex.org/I97750245"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":0.5309,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.63936278,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"22","issue":"2","first_page":"1984","last_page":"1999"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6378491520881653},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6149991154670715},{"id":"https://openalex.org/keywords/interaction-network","display_name":"Interaction network","score":0.5295223593711853},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.49545204639434814},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45805537700653076},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4570072591304779},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3674320876598358},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3470827043056488}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6378491520881653},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6149991154670715},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.5295223593711853},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.49545204639434814},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45805537700653076},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4570072591304779},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3674320876598358},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3470827043056488}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbz167","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbz167","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:32103253","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32103253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:repository.kaust.edu.sa:10754/661819","is_oa":false,"landing_page_url":"http://hdl.handle.net/10754/661819","pdf_url":null,"source":{"id":"https://openalex.org/S4306401596","display_name":"King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71920554","host_organization_name":"King Abdullah University of Science and Technology","host_organization_lineage":["https://openalex.org/I71920554"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1439405331","display_name":null,"funder_award_id":"FCC/1/1976-19-01","funder_id":"https://openalex.org/F4320322320","funder_display_name":"King Abdullah University of Science and Technology"},{"id":"https://openalex.org/G2411356598","display_name":null,"funder_award_id":"XDJK2020B028","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G3605984960","display_name":null,"funder_award_id":"XDJK2019B024","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5564147583","display_name":"\u9762\u5411\u53ef\u53d8\u526a\u63a5\u5f02\u6784\u4f53\u529f\u80fd\u9884\u6d4b\u7684\u6570\u636e\u6574\u5408\u65b9\u6cd5\u7814\u7a76","funder_award_id":"61872300","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G659245102","display_name":null,"funder_award_id":"61873214","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322320","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W1855299742","https://openalex.org/W1964427001","https://openalex.org/W1966331733","https://openalex.org/W1966985102","https://openalex.org/W1983623192","https://openalex.org/W1990153910","https://openalex.org/W1996442028","https://openalex.org/W1999332302","https://openalex.org/W2001780798","https://openalex.org/W2011912935","https://openalex.org/W2015284016","https://openalex.org/W2015631955","https://openalex.org/W2030057907","https://openalex.org/W2032551913","https://openalex.org/W2040263952","https://openalex.org/W2042851051","https://openalex.org/W2044433401","https://openalex.org/W2045156863","https://openalex.org/W2054035764","https://openalex.org/W2070413419","https://openalex.org/W2070571588","https://openalex.org/W2080390072","https://openalex.org/W2083597681","https://openalex.org/W2088891952","https://openalex.org/W2090295813","https://openalex.org/W2090978188","https://openalex.org/W2092180333","https://openalex.org/W2095319945","https://openalex.org/W2096283457","https://openalex.org/W2096606586","https://openalex.org/W2096766502","https://openalex.org/W2098924171","https://openalex.org/W2105325784","https://openalex.org/W2105924489","https://openalex.org/W2116298046","https://openalex.org/W2116798163","https://openalex.org/W2117692326","https://openalex.org/W2121443461","https://openalex.org/W2121906867","https://openalex.org/W2122683221","https://openalex.org/W2122769974","https://openalex.org/W2122778851","https://openalex.org/W2123696077","https://openalex.org/W2125414037","https://openalex.org/W2125984976","https://openalex.org/W2126172213","https://openalex.org/W2139227366","https://openalex.org/W2140141449","https://openalex.org/W2141222510","https://openalex.org/W2141811925","https://openalex.org/W2147326962","https://openalex.org/W2149082178","https://openalex.org/W2150026213","https://openalex.org/W2150045600","https://openalex.org/W2150757282","https://openalex.org/W2152154355","https://openalex.org/W2159482845","https://openalex.org/W2163798887","https://openalex.org/W2164298117","https://openalex.org/W2432138776","https://openalex.org/W2568642260","https://openalex.org/W2611492308","https://openalex.org/W2749320391","https://openalex.org/W2772618228","https://openalex.org/W2774736917","https://openalex.org/W2884736612","https://openalex.org/W2911989462","https://openalex.org/W2912785354","https://openalex.org/W2915536738","https://openalex.org/W2948113028","https://openalex.org/W2953661734","https://openalex.org/W2988775587","https://openalex.org/W4230962320","https://openalex.org/W4236875018","https://openalex.org/W4238448376","https://openalex.org/W4249273120","https://openalex.org/W4294216483","https://openalex.org/W6758753480","https://openalex.org/W6759046383","https://openalex.org/W6763421474"],"related_works":["https://openalex.org/W2737319532","https://openalex.org/W4392896533","https://openalex.org/W2062945643","https://openalex.org/W2050308539","https://openalex.org/W3151405604","https://openalex.org/W2565797512","https://openalex.org/W2464653720","https://openalex.org/W2468140709","https://openalex.org/W2798603412","https://openalex.org/W2094392347"],"abstract_inverted_index":{"Discovering":[0],"driver":[1,73,79,86,112,138,148,194,198,225,253,265,272],"pathways":[2,31,53,125,266,273],"is":[3,282],"an":[4],"essential":[5],"step":[6],"to":[7,15,24,30,70,83,100,140,152,167],"uncover":[8],"the":[9,25,33,85,101,104,129,136,159,164,169,181,187,203,229,240,275],"molecular":[10],"mechanism":[11],"underlying":[12],"cancer":[13,20,211],"and":[14,32,55,107,124,134,142,175,185,193,209,238,246,267],"explore":[16,168],"precise":[17],"treatments":[18],"for":[19],"patients.":[21],"However,":[22],"due":[23],"difficulties":[26],"of":[27,88,103,121,150,163,235,280],"mapping":[28],"genes":[29,94,151,226,254],"limited":[34],"knowledge":[35],"about":[36],"pathway":[37,153,182,188,241],"interactions,":[38],"most":[39],"previous":[40],"work":[41],"focus":[42],"on":[43,128,202],"identifying":[44],"individual":[45],"pathways.":[46,74,176,199],"In":[47,60,259],"practice,":[48],"two":[49],"(or":[50],"even":[51],"more)":[52],"interplay":[54],"often":[56],"cooperatively":[57],"trigger":[58],"cancer.":[59],"this":[61],"study,":[62],"we":[63],"proposed":[64],"a":[65,78,117],"new":[66],"approach":[67],"called":[68],"CDPathway":[69,76,91,156,220,261,281],"discover":[71],"cooperative":[72,197,271],"First,":[75],"introduces":[77],"impact":[80],"quantification":[81],"function":[82],"quantify":[84],"weight":[87],"each":[89],"gene.":[90],"assumes":[92],"that":[93,219],"with":[95,190],"larger":[96],"weights":[97,139,195],"contribute":[98],"more":[99,250,264,269],"occurrence":[102],"target":[105],"disease":[106],"identifies":[108,186,262],"them":[109,133],"as":[110,196],"candidate":[111,224],"genes.":[113],"Next,":[114],"it":[115,179,247],"constructs":[116],"heterogeneous":[118,165],"network":[119,166,184,243],"composed":[120],"genes,":[122,173],"miRNAs":[123,174],"nodes":[126],"based":[127],"known":[130,251],"intra(inter)-relations":[131],"between":[132,172],"assigns":[135],"quantified":[137],"gene-pathway":[141],"gene-miRNA":[143],"relational":[144],"edges.":[145],"To":[146],"transfer":[147],"impacts":[149],"interaction":[154,183,242],"pairs,":[155],"collaboratively":[157],"factorizes":[158],"weighted":[160],"adjacency":[161],"matrices":[162],"latent":[170],"relations":[171],"After":[177],"this,":[178],"reconstructs":[180],"pairs":[189],"maximal":[191],"interactive":[192],"Experimental":[200],"results":[201],"breast,":[204],"uterine":[205],"corpus":[206],"endometrial":[207],"carcinoma":[208],"ovarian":[210],"data":[212],"from":[213],"The":[214,278],"Cancer":[215],"Genome":[216],"Atlas":[217],"show":[218],"can":[221],"effectively":[222],"identify":[223],"[area":[227],"under":[228],"receiver":[230],"operating":[231],"characteristic":[232],"curve":[233],"(AUROC)":[234],"$\\geq":[236],"$0.9]":[237],"reconstruct":[239],"(AUROC":[244],"of>0.9),":[245],"uncovers":[248],"much":[249],"(potential)":[252],"than":[255,274],"other":[256],"competitive":[257],"methods.":[258,277],"addition,":[260],"150%":[263],"60%":[268],"potential":[270],"competing":[276],"code":[279],"available":[283],"at":[284],"http://mlda.swu.edu.cn/codes.php?name=CDPathway.":[285]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}