{"id":"https://openalex.org/W2912814435","doi":"https://doi.org/10.1093/bib/bbz006","title":"Decoding competing endogenous RNA networks for cancer biomarker discovery","display_name":"Decoding competing endogenous RNA networks for cancer biomarker discovery","publication_year":2019,"publication_date":"2019-01-05","ids":{"openalex":"https://openalex.org/W2912814435","doi":"https://doi.org/10.1093/bib/bbz006","mag":"2912814435","pmid":"https://pubmed.ncbi.nlm.nih.gov/30715152"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbz006","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbz006","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101425895","display_name":"Xin Qi","orcid":"https://orcid.org/0000-0001-9038-4287"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Qi","raw_affiliation_strings":["Center for Systems Biology, Soochow University, Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Systems Biology, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002365671","display_name":"Yuxin Lin","orcid":"https://orcid.org/0000-0001-6543-0317"},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuxin Lin","raw_affiliation_strings":["Center for Systems Biology, Soochow University, Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Systems Biology, Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100401009","display_name":"Jiajia Chen","orcid":"https://orcid.org/0000-0003-3659-0658"},"institutions":[{"id":"https://openalex.org/I308837","display_name":"Suzhou University of Science and Technology","ror":"https://ror.org/04en8wb91","country_code":"CN","type":"education","lineage":["https://openalex.org/I308837"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiajia Chen","raw_affiliation_strings":["School of Chemistry, Biology and Material Engineering, Suzhou University of Science and Technology, Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Biology and Material Engineering, Suzhou University of Science and Technology, Suzhou, China","institution_ids":["https://openalex.org/I308837"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081095213","display_name":"Bairong Shen","orcid":"https://orcid.org/0000-0003-2899-1531"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bairong Shen","raw_affiliation_strings":["Institutes for Systems Genetics, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institutes for Systems Genetics, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":2.8907,"has_fulltext":false,"cited_by_count":91,"citation_normalized_percentile":{"value":0.92419258,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"21","issue":"2","first_page":"441","last_page":"457"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/competing-endogenous-rna","display_name":"Competing endogenous RNA","score":0.9848092794418335},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6886711120605469},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6357102394104004},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6209103465080261},{"id":"https://openalex.org/keywords/crosstalk","display_name":"Crosstalk","score":0.5821500420570374},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"Carcinogenesis","score":0.5664268136024475},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.37609487771987915},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.30002447962760925},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.27444779872894287},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.2649112343788147},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"Long non-coding RNA","score":0.2484077513217926},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.21352624893188477}],"concepts":[{"id":"https://openalex.org/C60365752","wikidata":"https://www.wikidata.org/wiki/Q5156306","display_name":"Competing endogenous RNA","level":5,"score":0.9848092794418335},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6886711120605469},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6357102394104004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6209103465080261},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.5821500420570374},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5664268136024475},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37609487771987915},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30002447962760925},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.27444779872894287},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.2649112343788147},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.2484077513217926},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21352624893188477},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbz006","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbz006","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30715152","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30715152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.550000011920929}],"awards":[{"id":"https://openalex.org/G1468104968","display_name":"\u524d\u5217\u817a\u764c\u6f14\u53d8\u8fc7\u7a0b\u4e2d\u7684\u5173\u952e\u57fa\u56e0\u548c\u6a21\u5757\u53ca\u5176\u4f5c\u7528\u673a\u5236","funder_award_id":"31670851","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2542981004","display_name":null,"funder_award_id":"31600670","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4865473572","display_name":null,"funder_award_id":"31470821","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7349633688","display_name":null,"funder_award_id":"91530320","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8974385515","display_name":null,"funder_award_id":"2018K173C","funder_id":"https://openalex.org/F4320335471","funder_display_name":"Jiangsu Planned Projects for Postdoctoral Research Funds"},{"id":"https://openalex.org/G971478765","display_name":null,"funder_award_id":"31770903","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335471","display_name":"Jiangsu Planned Projects for Postdoctoral Research Funds","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":124,"referenced_works":["https://openalex.org/W91108901","https://openalex.org/W144423133","https://openalex.org/W1892363833","https://openalex.org/W1965514608","https://openalex.org/W1966498224","https://openalex.org/W1971623350","https://openalex.org/W1977852043","https://openalex.org/W1979587260","https://openalex.org/W1983738485","https://openalex.org/W1990478192","https://openalex.org/W1991153319","https://openalex.org/W2002995168","https://openalex.org/W2011458493","https://openalex.org/W2014092540","https://openalex.org/W2022192230","https://openalex.org/W2033966391","https://openalex.org/W2035365585","https://openalex.org/W2040191060","https://openalex.org/W2044601473","https://openalex.org/W2046387002","https://openalex.org/W2046621435","https://openalex.org/W2050108172","https://openalex.org/W2050642406","https://openalex.org/W2056573404","https://openalex.org/W2059073003","https://openalex.org/W2059794606","https://openalex.org/W2071138575","https://openalex.org/W2072016877","https://openalex.org/W2077327925","https://openalex.org/W2083381199","https://openalex.org/W2095691234","https://openalex.org/W2096465161","https://openalex.org/W2096858457","https://openalex.org/W2097554668","https://openalex.org/W2102107106","https://openalex.org/W2103726776","https://openalex.org/W2104806799","https://openalex.org/W2108000084","https://openalex.org/W2108230228","https://openalex.org/W2111479290","https://openalex.org/W2115221577","https://openalex.org/W2115662330","https://openalex.org/W2117977572","https://openalex.org/W2122708083","https://openalex.org/W2125571324","https://openalex.org/W2129447411","https://openalex.org/W2130687298","https://openalex.org/W2134629862","https://openalex.org/W2135398049","https://openalex.org/W2136222002","https://openalex.org/W2143662314","https://openalex.org/W2146573461","https://openalex.org/W2148512186","https://openalex.org/W2151721435","https://openalex.org/W2154085311","https://openalex.org/W2154947819","https://openalex.org/W2158135353","https://openalex.org/W2160068229","https://openalex.org/W2163025807","https://openalex.org/W2166810745","https://openalex.org/W2168546553","https://openalex.org/W2171344053","https://openalex.org/W2171580148","https://openalex.org/W2172312226","https://openalex.org/W2259986057","https://openalex.org/W2266524601","https://openalex.org/W2280316621","https://openalex.org/W2293634192","https://openalex.org/W2337819340","https://openalex.org/W2341291028","https://openalex.org/W2396470958","https://openalex.org/W2410060109","https://openalex.org/W2465067923","https://openalex.org/W2468543693","https://openalex.org/W2485229000","https://openalex.org/W2492222759","https://openalex.org/W2502770791","https://openalex.org/W2524314645","https://openalex.org/W2529089099","https://openalex.org/W2544684176","https://openalex.org/W2551303518","https://openalex.org/W2588585220","https://openalex.org/W2594978979","https://openalex.org/W2625078446","https://openalex.org/W2740075395","https://openalex.org/W2741267727","https://openalex.org/W2743180985","https://openalex.org/W2752304808","https://openalex.org/W2754764849","https://openalex.org/W2763795677","https://openalex.org/W2765243377","https://openalex.org/W2767546566","https://openalex.org/W2768422310","https://openalex.org/W2768632638","https://openalex.org/W2772391237","https://openalex.org/W2772593462","https://openalex.org/W2772847445","https://openalex.org/W2785637603","https://openalex.org/W2788982005","https://openalex.org/W2789382357","https://openalex.org/W2793661730","https://openalex.org/W2794194398","https://openalex.org/W2794738560","https://openalex.org/W2795686629","https://openalex.org/W2804265440","https://openalex.org/W2808263699","https://openalex.org/W2808651698","https://openalex.org/W2889313194","https://openalex.org/W2890631273","https://openalex.org/W3024808273","https://openalex.org/W3102334290","https://openalex.org/W4246271082","https://openalex.org/W4376652472","https://openalex.org/W6644976065","https://openalex.org/W6678518026","https://openalex.org/W6692872163","https://openalex.org/W6714389907","https://openalex.org/W6741696545","https://openalex.org/W6746063331","https://openalex.org/W6747635752","https://openalex.org/W6748956420","https://openalex.org/W6752083387","https://openalex.org/W6754875439","https://openalex.org/W6852717630"],"related_works":["https://openalex.org/W1998618295","https://openalex.org/W2605415066","https://openalex.org/W2586183753","https://openalex.org/W3134273865","https://openalex.org/W3135639358","https://openalex.org/W3144241576","https://openalex.org/W2113725788","https://openalex.org/W1988174701","https://openalex.org/W2057742104","https://openalex.org/W4283692078"],"abstract_inverted_index":{"Crosstalk":[0],"between":[1],"competing":[2,53],"endogenous":[3],"RNAs":[4],"(ceRNAs)":[5],"is":[6,24,98],"mediated":[7],"by":[8,73],"shared":[9],"microRNAs":[10],"(miRNAs)":[11],"and":[12,20,58,94,112,131,138,161,184,203],"plays":[13],"important":[14,186],"roles":[15],"both":[16],"in":[17,66,110,193],"normal":[18],"physiology":[19],"tumorigenesis;":[21],"thus,":[22],"it":[23],"attractive":[25],"for":[26,134,153,169,188,205],"systems-level":[27],"decoding":[28],"of":[29,38,42,63,77,99,108,115,126,166,180,200],"gene":[30],"regulation.":[31],"As":[32],"ceRNA":[33,67,96,116,135,139,159,167,182,190],"networks":[34,68,97,160],"link":[35],"the":[36,45,61,75,105,163,178,198],"function":[37,107],"miRNAs":[39],"with":[40],"that":[41,84],"transcripts":[43],"sharing":[44],"same":[46],"miRNA":[47],"response":[48],"elements":[49],"(MREs),":[50],"e.g.":[51],"pseudogenes,":[52],"mRNAs,":[54],"long":[55],"non-coding":[56],"RNAs,":[57,60],"circular":[59],"perturbation":[62],"crucial":[64,113],"interactions":[65,183],"may":[69],"contribute":[70],"to":[71,121],"carcinogenesis":[72],"affecting":[74],"balance":[76],"cellular":[78],"regulatory":[79,106],"system.":[80],"Therefore,":[81],"discovering":[82,189],"biomarkers":[83,168],"indicate":[85],"cancer":[86,111,170,194,206],"initiation,":[87],"development,":[88],"and/or":[89],"therapeutic":[90],"responses":[91],"via":[92],"reconstructing":[93],"analyzing":[95,158],"clinical":[100],"significance.":[101],"In":[102],"this":[103],"review,":[104],"ceRNAs":[109],"determinants":[114],"crosstalk":[117],"are":[118,142],"firstly":[119],"discussed":[120],"gain":[122],"a":[123,145],"global":[124],"understanding":[125],"ceRNA-mediated":[127],"carcinogenesis.":[128],"Then,":[129],"computational":[130],"experimental":[132],"approaches":[133],"network":[136],"reconstruction":[137],"validation,":[140],"respectively,":[141],"described":[143],"from":[144],"systems":[146],"biology":[147],"perspective.":[148],"We":[149],"focus":[150],"on":[151,157,177],"strategies":[152],"biomarker":[154,192],"identification":[155],"based":[156],"highlight":[162],"translational":[164],"applications":[165],"management.":[171],"This":[172],"article":[173],"will":[174],"shed":[175],"light":[176],"significance":[179],"miRNA-mediated":[181],"provide":[185],"clues":[187],"network-based":[191],"biology,":[195],"thereby":[196],"accelerating":[197],"pace":[199],"precision":[201],"medicine":[202],"healthcare":[204],"patients.":[207]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":7}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}