{"id":"https://openalex.org/W2258524607","doi":"https://doi.org/10.1093/bib/bbv053","title":"A literature mining-based approach for identification of cellular pathways associated with chemoresistance in cancer","display_name":"A literature mining-based approach for identification of cellular pathways associated with chemoresistance in cancer","publication_year":2015,"publication_date":"2015-07-27","ids":{"openalex":"https://openalex.org/W2258524607","doi":"https://doi.org/10.1093/bib/bbv053","mag":"2258524607","pmid":"https://pubmed.ncbi.nlm.nih.gov/26220932"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbv053","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbv053","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6283363","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078855608","display_name":"Jung Hun Oh","orcid":"https://orcid.org/0000-0001-8791-2755"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jung Hun Oh","raw_affiliation_strings":["Jung Hun Oh is an Assistant Attending Computer Scientist in the Department of Medical Physics at Memorial Sloan Kettering Cancer Center. His research interest includes bioinformatics, machine learning and statistical analysis","Department of Medical Physics at Memorial Sloan Kettering Cancer Center","Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1250 First Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jung Hun Oh is an Assistant Attending Computer Scientist in the Department of Medical Physics at Memorial Sloan Kettering Cancer Center. His research interest includes bioinformatics, machine learning and statistical analysis","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medical Physics at Memorial Sloan Kettering Cancer Center","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1250 First Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026159944","display_name":"Joseph O. Deasy","orcid":"https://orcid.org/0000-0002-9437-266X"},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph O. Deasy","raw_affiliation_strings":["Joseph O. Deasy is an Attending Physicist and Chair of the Department of Medical Physics at Memorial Sloan Kettering Cancer Center. His research focuses on applying statistical modeling to the analysis of large, complex data sets in oncology","Department of Medical Physics at Memorial Sloan Kettering Cancer Center","Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1250 First Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joseph O. Deasy is an Attending Physicist and Chair of the Department of Medical Physics at Memorial Sloan Kettering Cancer Center. His research focuses on applying statistical modeling to the analysis of large, complex data sets in oncology","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medical Physics at Memorial Sloan Kettering Cancer Center","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1250 First Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":3885,"currency":"USD","value_usd":3885},"apc_paid":null,"fwci":1.1101,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.77677439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"17","issue":"3","first_page":"468","last_page":"478"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.6422194838523865},{"id":"https://openalex.org/keywords/biological-pathway","display_name":"Biological pathway","score":0.5877598524093628},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5523510575294495},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5474770665168762},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5319348573684692},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.5091680884361267},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5086458921432495},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4941544830799103},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4891414940357208},{"id":"https://openalex.org/keywords/autophagy","display_name":"Autophagy","score":0.44252073764801025},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.43780848383903503},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.38291677832603455},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1802719235420227},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.12646570801734924}],"concepts":[{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.6422194838523865},{"id":"https://openalex.org/C9927688","wikidata":"https://www.wikidata.org/wiki/Q4915012","display_name":"Biological pathway","level":4,"score":0.5877598524093628},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5523510575294495},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5474770665168762},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5319348573684692},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5091680884361267},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5086458921432495},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4941544830799103},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4891414940357208},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.44252073764801025},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.43780848383903503},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.38291677832603455},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1802719235420227},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.12646570801734924},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/bib/bbv053","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbv053","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26220932","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26220932","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5256474","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6283363","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6283363","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6283363","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:bib:17/3/468","is_oa":false,"landing_page_url":"http://bib.oxfordjournals.org/cgi/content/short/17/3/468","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6283363","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6283363","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6800000071525574,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G897181964","display_name":null,"funder_award_id":"#P30-CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309468","display_name":"Memorial Sloan-Kettering Cancer Center","ror":"https://ror.org/02yrq0923"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":113,"referenced_works":["https://openalex.org/W161484625","https://openalex.org/W1414004483","https://openalex.org/W1483512429","https://openalex.org/W1580540249","https://openalex.org/W1588901901","https://openalex.org/W1611267195","https://openalex.org/W1761746131","https://openalex.org/W1819407996","https://openalex.org/W1911322167","https://openalex.org/W1964137986","https://openalex.org/W1965568527","https://openalex.org/W1967379345","https://openalex.org/W1968067958","https://openalex.org/W1973890143","https://openalex.org/W1978115823","https://openalex.org/W1978586737","https://openalex.org/W1979701357","https://openalex.org/W1981440982","https://openalex.org/W1982555987","https://openalex.org/W1983364027","https://openalex.org/W1985527634","https://openalex.org/W1987220193","https://openalex.org/W1987379253","https://openalex.org/W1990481297","https://openalex.org/W1992814850","https://openalex.org/W1995745530","https://openalex.org/W1997925705","https://openalex.org/W1999659639","https://openalex.org/W2002013266","https://openalex.org/W2006771504","https://openalex.org/W2009026877","https://openalex.org/W2017248899","https://openalex.org/W2017986614","https://openalex.org/W2020540837","https://openalex.org/W2022932085","https://openalex.org/W2023116290","https://openalex.org/W2030197665","https://openalex.org/W2036261922","https://openalex.org/W2037107824","https://openalex.org/W2037515450","https://openalex.org/W2037621239","https://openalex.org/W2038066298","https://openalex.org/W2039461396","https://openalex.org/W2043099534","https://openalex.org/W2043538870","https://openalex.org/W2045247817","https://openalex.org/W2045771317","https://openalex.org/W2049215013","https://openalex.org/W2049290799","https://openalex.org/W2051366772","https://openalex.org/W2051890222","https://openalex.org/W2052057604","https://openalex.org/W2054318449","https://openalex.org/W2057737464","https://openalex.org/W2060346337","https://openalex.org/W2062069198","https://openalex.org/W2062800114","https://openalex.org/W2062953502","https://openalex.org/W2063333132","https://openalex.org/W2064674946","https://openalex.org/W2065972400","https://openalex.org/W2068487380","https://openalex.org/W2070958946","https://openalex.org/W2071646545","https://openalex.org/W2073182905","https://openalex.org/W2077316068","https://openalex.org/W2079351077","https://openalex.org/W2081775759","https://openalex.org/W2082637548","https://openalex.org/W2083098214","https://openalex.org/W2087861588","https://openalex.org/W2088267142","https://openalex.org/W2089735922","https://openalex.org/W2092249151","https://openalex.org/W2092260148","https://openalex.org/W2092313221","https://openalex.org/W2097453652","https://openalex.org/W2099853576","https://openalex.org/W2100488521","https://openalex.org/W2100531566","https://openalex.org/W2103888171","https://openalex.org/W2105963609","https://openalex.org/W2106936371","https://openalex.org/W2112794562","https://openalex.org/W2117535432","https://openalex.org/W2119349084","https://openalex.org/W2121862456","https://openalex.org/W2124185479","https://openalex.org/W2126585177","https://openalex.org/W2127480567","https://openalex.org/W2128341240","https://openalex.org/W2134319564","https://openalex.org/W2139329774","https://openalex.org/W2140374399","https://openalex.org/W2143838754","https://openalex.org/W2150026213","https://openalex.org/W2150552947","https://openalex.org/W2157861747","https://openalex.org/W2158255028","https://openalex.org/W2158294714","https://openalex.org/W2159441446","https://openalex.org/W2162193348","https://openalex.org/W2163409417","https://openalex.org/W2166078316","https://openalex.org/W2170204650","https://openalex.org/W2170278621","https://openalex.org/W2170825753","https://openalex.org/W4242505789","https://openalex.org/W6606507521","https://openalex.org/W6628949587","https://openalex.org/W6634680967","https://openalex.org/W6659490176","https://openalex.org/W6680179368"],"related_works":["https://openalex.org/W3150996080","https://openalex.org/W2498134948","https://openalex.org/W3151903987","https://openalex.org/W4285596443","https://openalex.org/W2057742104","https://openalex.org/W4283692078","https://openalex.org/W1760163131","https://openalex.org/W312342747","https://openalex.org/W641470716","https://openalex.org/W78967844"],"abstract_inverted_index":{"Chemoresistance":[0],"is":[1],"a":[2,79,109,115,129],"major":[3],"obstacle":[4],"to":[5,44,83,91],"the":[6,46,55,65,93,104,134],"successful":[7],"treatment":[8],"of":[9,50,54,72,95,133,137],"many":[10,21],"human":[11],"cancer":[12,29,74],"types.":[13,75],"Increasing":[14],"evidence":[15],"has":[16],"revealed":[17],"that":[18],"chemoresistance":[19,59],"involves":[20],"genes":[22,69],"and":[23,36,70,126],"multiple":[24,73],"complex":[25],"biological":[26,56,87],"mechanisms":[27,49,57,136],"including":[28],"stem":[30],"cells,":[31],"drug":[32],"efflux":[33],"mechanism,":[34],"autophagy":[35],"epithelial-mesenchymal":[37],"transition.":[38],"Many":[39],"studies":[40],"have":[41],"been":[42],"conducted":[43],"investigate":[45,84,92],"possible":[47],"molecular":[48],"chemoresistance.":[51,138],"However,":[52],"understanding":[53],"in":[58,98,119],"still":[60],"remains":[61],"limited.":[62],"We":[63,76],"surveyed":[64],"literature":[66],"on":[67,114],"chemoresistance-related":[68,86,96],"pathways":[71],"then":[77],"used":[78,108],"curated":[80,105],"pathway":[81],"database":[82],"significant":[85],"pathways.":[88],"In":[89],"addition,":[90],"importance":[94],"markers":[97],"protein-protein":[99],"interaction":[100],"networks":[101],"identified":[102],"using":[103],"database,":[106],"we":[107],"gene-ranking":[110],"algorithm":[111],"designed":[112],"based":[113],"graph-based":[116],"scoring":[117],"function":[118],"our":[120],"previous":[121],"study.":[122],"Our":[123],"comprehensive":[124],"survey":[125],"analysis":[127],"provide":[128],"systems":[130],"biology-based":[131],"overview":[132],"underlying":[135]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2025-10-10T00:00:00"}