{"id":"https://openalex.org/W2150577353","doi":"https://doi.org/10.1093/bib/bbs034","title":"Data mining in the Life Sciences with Random Forest: a walk in the park or lost in the jungle?","display_name":"Data mining in the Life Sciences with Random Forest: a walk in the park or lost in the jungle?","publication_year":2012,"publication_date":"2012-07-10","ids":{"openalex":"https://openalex.org/W2150577353","doi":"https://doi.org/10.1093/bib/bbs034","mag":"2150577353","pmid":"https://pubmed.ncbi.nlm.nih.gov/22786785"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbs034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbs034","pdf_url":"https://academic.oup.com/bib/article-pdf/14/3/315/709597/bbs034.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bib/article-pdf/14/3/315/709597/bbs034.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018538550","display_name":"Wouter G. Touw","orcid":"https://orcid.org/0000-0002-0407-3923"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"W. G. Touw","raw_affiliation_strings":["Radboud University of Nijmegen, the Netherlands","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","the Radboud University Medical Centre, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Radboud University of Nijmegen, the Netherlands","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040732518","display_name":"Jumamurat R. Bayjanov","orcid":"https://orcid.org/0000-0002-0637-9950"},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. R. Bayjanov","raw_affiliation_strings":["the Radboud University Medical Centre, the Netherlands","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre"],"affiliations":[{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079662264","display_name":"Lex Overmars","orcid":null},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"L. Overmars","raw_affiliation_strings":["Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","the Radboud University Medical Centre, the Netherlands","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre"],"affiliations":[{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037534812","display_name":"Lisa I. Backus","orcid":"https://orcid.org/0000-0001-8058-8366"},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"L. Backus","raw_affiliation_strings":["Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","the Radboud University Medical Centre, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089395125","display_name":"Jos Boekhorst","orcid":"https://orcid.org/0000-0002-4807-7838"},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. Boekhorst","raw_affiliation_strings":["the Radboud University Medical Centre, the Netherlands","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in"],"affiliations":[{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063076124","display_name":"Michiel Wels","orcid":null},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. Wels","raw_affiliation_strings":["Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","the Radboud University Medical Centre, the Netherlands","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre"],"affiliations":[{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024324359","display_name":"Sacha A. F. T. van Hijum","orcid":"https://orcid.org/0000-0003-0741-2991"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S. A. F. T. van Hijum","raw_affiliation_strings":["Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","the Radboud University Medical Centre, the Netherlands","Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics"],"affiliations":[{"raw_affiliation_string":"Sciences at the Radboud University of Nijmegen, the Netherlands. He specializes in","institution_ids":["https://openalex.org/I145872427"]},{"raw_affiliation_string":"the Radboud University Medical Centre, the Netherlands","institution_ids":[]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics, Radboud University Medical Centre","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Centre for Molecular and Biomolecular Informatics at the Radboud University Medical Centre. Bioinformatics","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5018538550"],"corresponding_institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":9.7969,"has_fulltext":true,"cited_by_count":444,"citation_normalized_percentile":{"value":0.98842715,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"14","issue":"3","first_page":"315","last_page":"326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jungle","display_name":"Jungle","score":0.9838384985923767},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.6275850534439087},{"id":"https://openalex.org/keywords/random-walk","display_name":"Random walk","score":0.5829858779907227},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.39600226283073425},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.39456358551979065},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35439160466194153},{"id":"https://openalex.org/keywords/forestry","display_name":"Forestry","score":0.3255980610847473},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2312757670879364},{"id":"https://openalex.org/keywords/archaeology","display_name":"Archaeology","score":0.22665706276893616},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15826073288917542},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.14612874388694763}],"concepts":[{"id":"https://openalex.org/C2776410375","wikidata":"https://www.wikidata.org/wiki/Q191086","display_name":"Jungle","level":2,"score":0.9838384985923767},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.6275850534439087},{"id":"https://openalex.org/C121194460","wikidata":"https://www.wikidata.org/wiki/Q856741","display_name":"Random walk","level":2,"score":0.5829858779907227},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.39600226283073425},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.39456358551979065},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35439160466194153},{"id":"https://openalex.org/C97137747","wikidata":"https://www.wikidata.org/wiki/Q38112","display_name":"Forestry","level":1,"score":0.3255980610847473},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2312757670879364},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.22665706276893616},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15826073288917542},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.14612874388694763}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001690","descriptor_name":"Biological Science Disciplines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001690","descriptor_name":"Biological Science Disciplines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001690","descriptor_name":"Biological Science Disciplines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bib/bbs034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbs034","pdf_url":"https://academic.oup.com/bib/article-pdf/14/3/315/709597/bbs034.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22786785","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22786785","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:2656448","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3659301","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/119255","is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/119255","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Briefings in Bioinformatics, 14, 3, pp. 315-26","raw_type":"Article / Letter to editor"}],"best_oa_location":{"id":"doi:10.1093/bib/bbs034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbs034","pdf_url":"https://academic.oup.com/bib/article-pdf/14/3/315/709597/bbs034.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.550000011920929,"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production"},{"score":0.5,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2150577353.pdf","grobid_xml":"https://content.openalex.org/works/W2150577353.grobid-xml"},"referenced_works_count":112,"referenced_works":["https://openalex.org/W273955616","https://openalex.org/W1498436455","https://openalex.org/W1520812622","https://openalex.org/W1539593569","https://openalex.org/W1554944419","https://openalex.org/W1594031697","https://openalex.org/W1599871777","https://openalex.org/W1600199800","https://openalex.org/W1606766780","https://openalex.org/W1678356000","https://openalex.org/W1797956629","https://openalex.org/W1817561967","https://openalex.org/W1875061881","https://openalex.org/W1967320885","https://openalex.org/W1971042695","https://openalex.org/W1975990978","https://openalex.org/W1978005360","https://openalex.org/W1978486653","https://openalex.org/W1990932448","https://openalex.org/W1993601578","https://openalex.org/W1995341919","https://openalex.org/W1997107638","https://openalex.org/W1997875345","https://openalex.org/W2001619934","https://openalex.org/W2001710803","https://openalex.org/W2008667922","https://openalex.org/W2009374545","https://openalex.org/W2012219352","https://openalex.org/W2014841186","https://openalex.org/W2022441134","https://openalex.org/W2023098599","https://openalex.org/W2031494645","https://openalex.org/W2032230795","https://openalex.org/W2034489756","https://openalex.org/W2035778775","https://openalex.org/W2037306412","https://openalex.org/W2040870580","https://openalex.org/W2041032262","https://openalex.org/W2044863747","https://openalex.org/W2045031658","https://openalex.org/W2046649434","https://openalex.org/W2047774682","https://openalex.org/W2049738506","https://openalex.org/W2053088580","https://openalex.org/W2053355118","https://openalex.org/W2057545775","https://openalex.org/W2057847565","https://openalex.org/W2058498750","https://openalex.org/W2058646847","https://openalex.org/W2061574900","https://openalex.org/W2062403173","https://openalex.org/W2064099652","https://openalex.org/W2067186215","https://openalex.org/W2068873381","https://openalex.org/W2071391537","https://openalex.org/W2078769511","https://openalex.org/W2079591220","https://openalex.org/W2083551126","https://openalex.org/W2086099578","https://openalex.org/W2087347434","https://openalex.org/W2091374137","https://openalex.org/W2096279453","https://openalex.org/W2098740506","https://openalex.org/W2100827857","https://openalex.org/W2101298000","https://openalex.org/W2103979596","https://openalex.org/W2108028755","https://openalex.org/W2108723074","https://openalex.org/W2112081648","https://openalex.org/W2112269540","https://openalex.org/W2114973325","https://openalex.org/W2115380778","https://openalex.org/W2117460135","https://openalex.org/W2118737745","https://openalex.org/W2119821739","https://openalex.org/W2119842880","https://openalex.org/W2120204563","https://openalex.org/W2121907028","https://openalex.org/W2122600131","https://openalex.org/W2122893222","https://openalex.org/W2123427204","https://openalex.org/W2123998733","https://openalex.org/W2126218947","https://openalex.org/W2128207034","https://openalex.org/W2131822674","https://openalex.org/W2133138357","https://openalex.org/W2135893370","https://openalex.org/W2136204986","https://openalex.org/W2137219016","https://openalex.org/W2139070508","https://openalex.org/W2139639280","https://openalex.org/W2140407975","https://openalex.org/W2141270567","https://openalex.org/W2143481518","https://openalex.org/W2143544846","https://openalex.org/W2144327682","https://openalex.org/W2144587714","https://openalex.org/W2145786566","https://openalex.org/W2145835338","https://openalex.org/W2152447806","https://openalex.org/W2152905639","https://openalex.org/W2153921000","https://openalex.org/W2154298141","https://openalex.org/W2155770902","https://openalex.org/W2164050575","https://openalex.org/W2165118109","https://openalex.org/W2171558600","https://openalex.org/W2911964244","https://openalex.org/W2964057329","https://openalex.org/W3085162807","https://openalex.org/W4246259708","https://openalex.org/W4249977334"],"related_works":["https://openalex.org/W604776852","https://openalex.org/W2156795617","https://openalex.org/W1524104001","https://openalex.org/W1900808973","https://openalex.org/W4239404776","https://openalex.org/W4239501966","https://openalex.org/W1561523934","https://openalex.org/W2059082536","https://openalex.org/W3122613655","https://openalex.org/W2808045821"],"abstract_inverted_index":{"In":[0,89],"the":[1,15,40,82,90,131,178,190,193,196,204,206,220],"Life":[2,91],"Sciences":[3],"'omics'":[4],"data":[5,19,87,179,230],"is":[6,75,94],"increasingly":[7],"generated":[8],"by":[9,189],"different":[10,65,165],"high-throughput":[11],"technologies.":[12],"Often":[13],"only":[14],"integration":[16],"of":[17,84,109,128,130,139,151,158,167,195,203,208],"these":[18,85,183],"allows":[20],"uncovering":[21],"biological":[22,221],"insights":[23,222],"that":[24,153,217,223],"can":[25,172,224],"be":[26,146,175,225],"experimentally":[27],"validated":[28],"or":[29,117,212],"mechanistically":[30],"modelled,":[31],"i.e.":[32],"sophisticated":[33],"computational":[34],"approaches":[35],"are":[36,122,184],"required":[37],"to":[38,63,205],"extract":[39],"complex":[41,228],"non-linear":[42],"trends":[43],"present":[44],"in":[45,59,173],"omics":[46,114,229],"data.":[47],"Classification":[48],"techniques":[49],"allow":[50,218],"training":[51],"a":[52,76,101,126,137,149,155,164],"model":[53],"based":[54],"on":[55,107],"variables":[56,110,116,121],"(e.g.":[57,67],"SNPs":[58],"genetic":[60],"association":[61],"studies)":[62],"separate":[64],"classes":[66],"healthy":[68],"subjects":[69],"versus":[70],"patients).":[71],"Random":[72],"Forest":[73],"(RF)":[74],"versatile":[77],"classification":[78,98,197],"algorithm":[79,191],"suited":[80],"for":[81,111,125,148,163],"analysis":[83],"large":[86],"sets.":[88],"Sciences,":[92],"RF":[93,97,181,215],"popular":[95],"because":[96],"models":[99],"have":[100,154],"high-prediction":[102],"accuracy":[103],"and":[104],"provide":[105],"information":[106],"importance":[108],"classification.":[112],"For":[113,134],"data,":[115],"conditional":[118,170],"relations":[119],"between":[120],"typically":[123],"important":[124,147,162],"subset":[127,150,166],"samples":[129],"same":[132],"class.":[133],"example:":[135],"within":[136],"class":[138],"cancer":[140],"patients":[141,152],"certain":[142],"SNP":[143],"combinations":[144],"may":[145],"specific":[156],"subtype":[157],"cancer,":[159],"but":[160],"not":[161],"patients.":[168],"These":[169],"relationships":[171],"principle":[174],"uncovered":[176],"from":[177,227],"with":[180],"as":[182],"implicitly":[185],"taken":[186],"into":[187],"account":[188],"during":[192],"creation":[194],"model.":[198],"This":[199],"review":[200],"details":[201],"some":[202],"best":[207],"our":[209],"knowledge":[210],"rarely":[211],"never":[213],"used":[214],"properties":[216],"maximizing":[219],"extracted":[226],"sets":[231],"using":[232],"RF.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":34},{"year":2024,"cited_by_count":29},{"year":2023,"cited_by_count":30},{"year":2022,"cited_by_count":71},{"year":2021,"cited_by_count":42},{"year":2020,"cited_by_count":40},{"year":2019,"cited_by_count":37},{"year":2018,"cited_by_count":31},{"year":2017,"cited_by_count":29},{"year":2016,"cited_by_count":24},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2016-06-24T00:00:00"}
