{"id":"https://openalex.org/W7163677768","doi":"https://doi.org/10.1093/bib/bbag290","title":"CSIE: cancer subtyping via inference and ensemble","display_name":"CSIE: cancer subtyping via inference and ensemble","publication_year":2026,"publication_date":"2026-05-01","ids":{"openalex":"https://openalex.org/W7163677768","doi":"https://doi.org/10.1093/bib/bbag290","pmid":"https://pubmed.ncbi.nlm.nih.gov/42242686"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbag290","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbag290","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbag290","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102956681","display_name":"Dieu Tran","orcid":"https://orcid.org/0000-0002-2805-7805"},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dao Tran","raw_affiliation_strings":["Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060843396","display_name":"Yen Thi\u2010Hai Pham","orcid":"https://orcid.org/0009-0001-3235-2110"},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yen Thi-Hai Pham","raw_affiliation_strings":["Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute , 6670 Bertner Ave, Houston, TX 77030 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute , 6670 Bertner Ave, Houston, TX 77030 ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072644863","display_name":"Hung N. Luu","orcid":"https://orcid.org/0000-0002-2172-1849"},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hung N Luu","raw_affiliation_strings":["Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute , 6670 Bertner Ave, Houston, TX 77030 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute , 6670 Bertner Ave, Houston, TX 77030 ,","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057906211","display_name":"Juli Petereit","orcid":"https://orcid.org/0000-0002-8017-3280"},"institutions":[{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juli Petereit","raw_affiliation_strings":["Nevada Bioinformatics Center, University of Nevada , Reno, 1664 N Virginia St, Reno, NV 89557 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nevada Bioinformatics Center, University of Nevada , Reno, 1664 N Virginia St, Reno, NV 89557 ,","institution_ids":["https://openalex.org/I134113660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119704344","display_name":"Manuel A Andrade-Rodriguez","orcid":null},"institutions":[{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manuel A Andrade-Rodriguez","raw_affiliation_strings":["Department of Agriculture, Veterinary and Rangeland Sciences, University of Nevada , Reno, 1664 N Virginia St, Reno, NV 89557 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agriculture, Veterinary and Rangeland Sciences, University of Nevada , Reno, 1664 N Virginia St, Reno, NV 89557 ,","institution_ids":["https://openalex.org/I134113660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107198559","display_name":"Phi Bya","orcid":null},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phi Bya","raw_affiliation_strings":["Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5137926521","display_name":"Tin Nguyen","orcid":null},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]},{"id":"https://openalex.org/I4210090317","display_name":"The Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800590384","https://openalex.org/I4210090317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tin Nguyen","raw_affiliation_strings":["Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,","Karmanos Cancer Institute, Wayne State University School of Medicine , 4100 John R St, Detroit, MI 48201 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, Wayne State University , 4815 4th St, Detroit, MI 48201 ,","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Karmanos Cancer Institute, Wayne State University School of Medicine , 4100 John R St, Detroit, MI 48201 ,","institution_ids":["https://openalex.org/I4210090317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5137926521"],"corresponding_institution_ids":["https://openalex.org/I185443292","https://openalex.org/I4210090317"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.52795056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.47290000319480896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.47290000319480896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.1265999972820282,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.11999999731779099,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subtyping","display_name":"Subtyping","score":0.8853999972343445},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.7656999826431274},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6579999923706055},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5773000121116638},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.51910001039505},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.46799999475479126},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C83852419","wikidata":"https://www.wikidata.org/wiki/Q2713292","display_name":"Subtyping","level":2,"score":0.8853999972343445},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.7656999826431274},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7289999723434448},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6579999923706055},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.590499997138977},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5773000121116638},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.51910001039505},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4699999988079071},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.46799999475479126},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.45899999141693115},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.40799999237060547},{"id":"https://openalex.org/C138958017","wikidata":"https://www.wikidata.org/wiki/Q190087","display_name":"Data type","level":2,"score":0.4050000011920929},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.398499995470047},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.37709999084472656},{"id":"https://openalex.org/C94124525","wikidata":"https://www.wikidata.org/wiki/Q912550","display_name":"Categorization","level":2,"score":0.36039999127388},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.3456999957561493},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.32690000534057617},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.3138999938964844},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.2953999936580658}],"mesh":[{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098430","descriptor_name":"Clustering Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098430","descriptor_name":"Clustering Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098430","descriptor_name":"Clustering Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098430","descriptor_name":"Clustering Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbag290","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbag290","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:42242686","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42242686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13235743","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13235743/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbag290","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbag290","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1966683941","display_name":null,"funder_award_id":"1R44GM152152-01","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2405032565","display_name":"FET: III: Small: Innovative Approaches for Bias Correction and Systems-level Analysis in Integrated Multi-omics Data","funder_award_id":"2203236","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G568089319","display_name":null,"funder_award_id":"1U01CA274573-01A1","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G778032529","display_name":null,"funder_award_id":"2023-67022-40041","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G8244293504","display_name":"CAREER: Integrative Pathway Analysis for Cancer Subtyping, Patient Stratification, and Risk Prediction","funder_award_id":"2343019","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G926880157","display_name":null,"funder_award_id":"80NSSC22M0255","funder_id":"https://openalex.org/F4320306101","funder_display_name":"National Aeronautics and Space Administration"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W1548779692","https://openalex.org/W1967442749","https://openalex.org/W1971395348","https://openalex.org/W1977247044","https://openalex.org/W1983790767","https://openalex.org/W1987219048","https://openalex.org/W1987971958","https://openalex.org/W2000703258","https://openalex.org/W2020859582","https://openalex.org/W2022401242","https://openalex.org/W2022832778","https://openalex.org/W2023461603","https://openalex.org/W2044055595","https://openalex.org/W2046318151","https://openalex.org/W2049760535","https://openalex.org/W2095763169","https://openalex.org/W2105268089","https://openalex.org/W2110065044","https://openalex.org/W2114505219","https://openalex.org/W2115547324","https://openalex.org/W2118883481","https://openalex.org/W2120862613","https://openalex.org/W2129099812","https://openalex.org/W2132132957","https://openalex.org/W2135000328","https://openalex.org/W2141599838","https://openalex.org/W2147000598","https://openalex.org/W2147799947","https://openalex.org/W2151936673","https://openalex.org/W2185729964","https://openalex.org/W2592760610","https://openalex.org/W2593738187","https://openalex.org/W2601026776","https://openalex.org/W2611654275","https://openalex.org/W2626481916","https://openalex.org/W2732456683","https://openalex.org/W2753385986","https://openalex.org/W2765654979","https://openalex.org/W2783685429","https://openalex.org/W2784057214","https://openalex.org/W2801812177","https://openalex.org/W2810475801","https://openalex.org/W2886216714","https://openalex.org/W2890682889","https://openalex.org/W2906107882","https://openalex.org/W2906317964","https://openalex.org/W2935931739","https://openalex.org/W2944869129","https://openalex.org/W2949273159","https://openalex.org/W2950878899","https://openalex.org/W2951033368","https://openalex.org/W2951209146","https://openalex.org/W2962898354","https://openalex.org/W2963144883","https://openalex.org/W2963466847","https://openalex.org/W2969985801","https://openalex.org/W2972661346","https://openalex.org/W2991023348","https://openalex.org/W3004060585","https://openalex.org/W3009560356","https://openalex.org/W3036271015","https://openalex.org/W3045428751","https://openalex.org/W3092007298","https://openalex.org/W3095252657","https://openalex.org/W3118311341","https://openalex.org/W3126609356","https://openalex.org/W3130672622","https://openalex.org/W3132427086","https://openalex.org/W3153221280","https://openalex.org/W3165022492","https://openalex.org/W3174312863","https://openalex.org/W3178302783","https://openalex.org/W3187957129","https://openalex.org/W3199258042","https://openalex.org/W3202182910","https://openalex.org/W3206271851","https://openalex.org/W3213334042","https://openalex.org/W4207063191","https://openalex.org/W4220788111","https://openalex.org/W4224291115","https://openalex.org/W4252676770","https://openalex.org/W4281636170","https://openalex.org/W4307201601","https://openalex.org/W4309976975","https://openalex.org/W4318979782","https://openalex.org/W4324139373","https://openalex.org/W4378782144","https://openalex.org/W4381248780","https://openalex.org/W4382068604","https://openalex.org/W4382462992","https://openalex.org/W4385429828","https://openalex.org/W4386424835","https://openalex.org/W4387118569","https://openalex.org/W4391539991","https://openalex.org/W4392807611","https://openalex.org/W4395954533","https://openalex.org/W4396688244","https://openalex.org/W4396954023","https://openalex.org/W4400918440","https://openalex.org/W4402600863","https://openalex.org/W4403397640","https://openalex.org/W4405972101","https://openalex.org/W4406270837","https://openalex.org/W4406431707","https://openalex.org/W4407293153","https://openalex.org/W4409444976","https://openalex.org/W4416205233","https://openalex.org/W4417497478"],"related_works":[],"abstract_inverted_index":{"While":[0],"multi-omics":[1,80],"integration":[2],"is":[3,13,100],"the":[4,17,141],"gold":[5],"standard":[6],"for":[7,152,159,174],"precision":[8],"oncology,":[9],"its":[10],"clinical":[11,165],"utility":[12],"severely":[14],"hampered":[15],"by":[16,49],"incomplete":[18,136],"data":[19,81,121,146,153],"problem,":[20],"where":[21],"cost":[22],"and":[23,41,86,118,172],"technical":[24],"barriers":[25],"often":[26],"leave":[27],"researchers":[28],"with":[29,113,135],"only":[30],"single-omics":[31],"profiles.":[32],"Our":[33,123],"manuscript":[34],"introduces":[35],"CSIE":[36,71,99,127,171],"(cancer":[37],"subtyping":[38,162],"via":[39,82],"inference":[40,54],"ensemble),":[42],"a":[43,51,156],"framework":[44],"that":[45,77,126],"bridges":[46],"this":[47,179],"gap":[48],"using":[50],"novel":[52],"transformer-based":[53],"module":[55,76],"which":[56],"incorporates":[57],"systems-level":[58],"knowledge":[59],"to":[60,89,148],"accurately":[61],"infer":[62],"missing":[63],"omics":[64],"layers":[65],"from":[66,143],"gene":[67],"expression":[68],"data.":[69,137],"Furthermore,":[70],"employs":[72],"an":[73],"ensemble":[74],"clustering":[75,87],"simultaneously":[78],"integrates":[79],"different":[83],"similarity":[84],"metrics":[85],"algorithms":[88],"capture":[90],"molecular":[91],"patterns":[92],"of":[93,98,170],"cancer":[94,111,161],"subtypes.":[95],"The":[96],"robustness":[97],"validated":[101],"through":[102],"extensive":[103],"benchmarking":[104],"against":[105],"12":[106],"state-of-the-art":[107],"methods":[108],"across":[109],"66":[110],"datasets":[112],"over":[114],"15":[115],"000":[116],"patients":[117],"22":[119],"diverse":[120],"modalities/platforms.":[122],"results":[124,176],"demonstrate":[125],"significantly":[128],"outperforms":[129],"existing":[130],"tools,":[131],"particularly":[132],"in":[133,163,178],"scenarios":[134],"This":[138],"work":[139],"shifts":[140],"paradigm":[142],"requiring":[144],"exhaustive":[145],"collection":[147],"leveraging":[149],"biological":[150],"intelligence":[151],"completion,":[154],"offering":[155],"scalable":[157],"solution":[158],"high-resolution":[160],"real-world":[164],"settings.":[166],"All":[167],"source":[168],"code":[169],"scripts":[173],"regenerating":[175],"reported":[177],"article":[180],"are":[181],"available":[182],"at":[183],"https://github.com/tinnlab/CSIE.":[184]},"counts_by_year":[],"updated_date":"2026-08-16T07:02:28.622633","created_date":"2026-06-06T00:00:00"}