{"id":"https://openalex.org/W4415773044","doi":"https://doi.org/10.1093/bib/bbaf575","title":"CRISPR-GATE: a one-stop repository and guide to computational resources for genome editing experimentation","display_name":"CRISPR-GATE: a one-stop repository and guide to computational resources for genome editing experimentation","publication_year":2025,"publication_date":"2025-08-31","ids":{"openalex":"https://openalex.org/W4415773044","doi":"https://doi.org/10.1093/bib/bbaf575","pmid":"https://pubmed.ncbi.nlm.nih.gov/41171707"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaf575","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf575","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbaf575","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120104026","display_name":"Asif Ali Vadakkethil","orcid":null},"institutions":[{"id":"https://openalex.org/I1141210","display_name":"Indian Agricultural Statistics Research Institute","ror":"https://ror.org/03kkevc75","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1141210","https://openalex.org/I179420787"]},{"id":"https://openalex.org/I121847817","display_name":"The Graduate Center, CUNY","ror":"https://ror.org/00awd9g61","country_code":"US","type":"education","lineage":["https://openalex.org/I121847817"]},{"id":"https://openalex.org/I45509622","display_name":"Indian Agricultural Research Institute","ror":"https://ror.org/01bzgdw81","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I45509622"]}],"countries":["IN","US"],"is_corresponding":true,"raw_author_name":"Asif Ali Vadakkethil","raw_affiliation_strings":["Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","The Graduate School, ICAR-Indian Agricultural Research Institute, PUSA Campus, New Delhi \u00a0 110012 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I1141210"]},{"raw_affiliation_string":"The Graduate School, ICAR-Indian Agricultural Research Institute, PUSA Campus, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I121847817","https://openalex.org/I1141210","https://openalex.org/I45509622"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049555132","display_name":"Sonali Panda","orcid":null},"institutions":[{"id":"https://openalex.org/I6013171","display_name":"Ravenshaw University","ror":"https://ror.org/014ecgm61","country_code":"IN","type":"education","lineage":["https://openalex.org/I6013171"]},{"id":"https://openalex.org/I77541275","display_name":"Central Rice Research Institute","ror":"https://ror.org/029zb5621","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I77541275"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sonali Panda","raw_affiliation_strings":["Department of Botany, Ravenshaw University , Cuttack 753003, Odisha ,","ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Botany, Ravenshaw University , Cuttack 753003, Odisha ,","institution_ids":["https://openalex.org/I6013171"]},{"raw_affiliation_string":"ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,","institution_ids":["https://openalex.org/I77541275"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Aranya Mitra","orcid":null},"institutions":[{"id":"https://openalex.org/I157674215","display_name":"Presidency University","ror":"https://ror.org/04xgbph11","country_code":"IN","type":"education","lineage":["https://openalex.org/I157674215"]},{"id":"https://openalex.org/I226431899","display_name":"West Bengal University of Health Sciences","ror":"https://ror.org/03fag5224","country_code":"IN","type":"education","lineage":["https://openalex.org/I226431899"]},{"id":"https://openalex.org/I4210132279","display_name":"Presidency University","ror":"https://ror.org/03vzjn737","country_code":"BD","type":"education","lineage":["https://openalex.org/I4210132279"]}],"countries":["BD","IN"],"is_corresponding":false,"raw_author_name":"Aranya Mitra","raw_affiliation_strings":["Institute of Health Sciences, Presidency University , Kolkata, West Bengal 700156 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Health Sciences, Presidency University , Kolkata, West Bengal 700156 ,","institution_ids":["https://openalex.org/I4210132279","https://openalex.org/I157674215","https://openalex.org/I226431899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038117708","display_name":"Manaswini Dash","orcid":"https://orcid.org/0000-0003-3237-7323"},"institutions":[{"id":"https://openalex.org/I77541275","display_name":"Central Rice Research Institute","ror":"https://ror.org/029zb5621","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I77541275"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manaswini Dash","raw_affiliation_strings":["ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,","institution_ids":["https://openalex.org/I77541275"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045584562","display_name":"Mirza Jaynul Baig","orcid":"https://orcid.org/0000-0001-8229-6471"},"institutions":[{"id":"https://openalex.org/I77541275","display_name":"Central Rice Research Institute","ror":"https://ror.org/029zb5621","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I77541275"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mirza J Baig","raw_affiliation_strings":["ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,","institution_ids":["https://openalex.org/I77541275"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036143033","display_name":"U. B. Angadi","orcid":"https://orcid.org/0000-0003-0012-0179"},"institutions":[{"id":"https://openalex.org/I1141210","display_name":"Indian Agricultural Statistics Research Institute","ror":"https://ror.org/03kkevc75","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1141210","https://openalex.org/I179420787"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ulavappa B Angadi","raw_affiliation_strings":["Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I1141210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024163625","display_name":"Dinesh Babu Uthaya Kumar","orcid":"https://orcid.org/0000-0001-7210-5811"},"institutions":[{"id":"https://openalex.org/I1141210","display_name":"Indian Agricultural Statistics Research Institute","ror":"https://ror.org/03kkevc75","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1141210","https://openalex.org/I179420787"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dinesh Kumar","raw_affiliation_strings":["Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I1141210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030265774","display_name":"Sarika Jaiswal","orcid":"https://orcid.org/0000-0002-9948-4994"},"institutions":[{"id":"https://openalex.org/I1141210","display_name":"Indian Agricultural Statistics Research Institute","ror":"https://ror.org/03kkevc75","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1141210","https://openalex.org/I179420787"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sarika Jaiswal","raw_affiliation_strings":["Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,"],"raw_orcid":"https://orcid.org/0000-0002-9948-4994","affiliations":[{"raw_affiliation_string":"Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I1141210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081736625","display_name":"Mir Asif Iquebal","orcid":"https://orcid.org/0000-0003-3787-5997"},"institutions":[{"id":"https://openalex.org/I1141210","display_name":"Indian Agricultural Statistics Research Institute","ror":"https://ror.org/03kkevc75","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1141210","https://openalex.org/I179420787"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mir Asif Iquebal","raw_affiliation_strings":["Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, New Delhi \u00a0 110012 ,","institution_ids":["https://openalex.org/I1141210"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062205493","display_name":"Kutubuddin A. Molla","orcid":"https://orcid.org/0000-0002-9897-7906"},"institutions":[{"id":"https://openalex.org/I77541275","display_name":"Central Rice Research Institute","ror":"https://ror.org/029zb5621","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I77541275"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kutubuddin A Molla","raw_affiliation_strings":["ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,"],"raw_orcid":"https://orcid.org/0000-0002-9897-7906","affiliations":[{"raw_affiliation_string":"ICAR- Central Rice Research Institute , Cuttack 753006, Odisha ,","institution_ids":["https://openalex.org/I77541275"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5120104026"],"corresponding_institution_ids":["https://openalex.org/I1141210","https://openalex.org/I121847817","https://openalex.org/I45509622"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":0.7015,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.75600282,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"26","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.978600025177002,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.978600025177002,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.015300000086426735,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crispr","display_name":"CRISPR","score":0.7429999709129333},{"id":"https://openalex.org/keywords/repurposing","display_name":"Repurposing","score":0.6590999960899353},{"id":"https://openalex.org/keywords/genome-editing","display_name":"Genome editing","score":0.6067000031471252},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5648999810218811},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.513700008392334},{"id":"https://openalex.org/keywords/web-application","display_name":"Web application","score":0.4778999984264374},{"id":"https://openalex.org/keywords/web-resource","display_name":"Web resource","score":0.3833000063896179}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7649999856948853},{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.7429999709129333},{"id":"https://openalex.org/C519536355","wikidata":"https://www.wikidata.org/wiki/Q21021151","display_name":"Repurposing","level":2,"score":0.6590999960899353},{"id":"https://openalex.org/C144501496","wikidata":"https://www.wikidata.org/wiki/Q5533489","display_name":"Genome editing","level":4,"score":0.6067000031471252},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5648999810218811},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.513700008392334},{"id":"https://openalex.org/C118643609","wikidata":"https://www.wikidata.org/wiki/Q189210","display_name":"Web application","level":2,"score":0.4778999984264374},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.45019999146461487},{"id":"https://openalex.org/C65603577","wikidata":"https://www.wikidata.org/wiki/Q3427877","display_name":"Web resource","level":2,"score":0.3833000063896179},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.36160001158714294},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3447999954223633},{"id":"https://openalex.org/C2781148417","wikidata":"https://www.wikidata.org/wiki/Q5533486","display_name":"Genome browser","level":5,"score":0.3384999930858612},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.31540000438690186},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.31130000948905945},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.2736000120639801},{"id":"https://openalex.org/C4554734","wikidata":"https://www.wikidata.org/wiki/Q593744","display_name":"Knowledge base","level":2,"score":0.26489999890327454},{"id":"https://openalex.org/C69075417","wikidata":"https://www.wikidata.org/wiki/Q515701","display_name":"Linked data","level":3,"score":0.2615000009536743}],"mesh":[{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000094704","descriptor_name":"RNA, Guide, CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000094704","descriptor_name":"RNA, Guide, CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000094704","descriptor_name":"RNA, Guide, CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000094704","descriptor_name":"RNA, Guide, CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000094704","descriptor_name":"RNA, Guide, CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064112","descriptor_name":"Clustered Regularly Interspaced Short Palindromic Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064112","descriptor_name":"Clustered Regularly Interspaced Short Palindromic Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064112","descriptor_name":"Clustered Regularly Interspaced Short Palindromic Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064112","descriptor_name":"Clustered Regularly Interspaced Short Palindromic Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064112","descriptor_name":"Clustered Regularly Interspaced Short Palindromic Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbaf575","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf575","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41171707","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41171707","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:11386235","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12576957","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbaf575","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf575","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320769","display_name":"Indian Council of Agricultural Research","ror":"https://ror.org/04fw54a43"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":311,"referenced_works":["https://openalex.org/W1869792624","https://openalex.org/W1879165674","https://openalex.org/W1892406518","https://openalex.org/W1912701812","https://openalex.org/W1915704240","https://openalex.org/W1940605149","https://openalex.org/W1963554509","https://openalex.org/W1968342623","https://openalex.org/W1973468599","https://openalex.org/W2000046950","https://openalex.org/W2003082286","https://openalex.org/W2003171404","https://openalex.org/W2009790316","https://openalex.org/W2013018092","https://openalex.org/W2021767455","https://openalex.org/W2024177760","https://openalex.org/W2024199022","https://openalex.org/W2036176224","https://openalex.org/W2042033410","https://openalex.org/W2043890495","https://openalex.org/W2055043387","https://openalex.org/W2060573994","https://openalex.org/W2066783444","https://openalex.org/W2075230442","https://openalex.org/W2077381938","https://openalex.org/W2097656459","https://openalex.org/W2100122648","https://openalex.org/W2105187403","https://openalex.org/W2106070783","https://openalex.org/W2107959600","https://openalex.org/W2114245320","https://openalex.org/W2115603949","https://openalex.org/W2127391962","https://openalex.org/W2128758977","https://openalex.org/W2134023754","https://openalex.org/W2134298288","https://openalex.org/W2134941170","https://openalex.org/W2135689945","https://openalex.org/W2137675802","https://openalex.org/W2137721714","https://openalex.org/W2145782793","https://openalex.org/W2149635735","https://openalex.org/W2151831732","https://openalex.org/W2157205823","https://openalex.org/W2158322625","https://openalex.org/W2160051211","https://openalex.org/W2161871693","https://openalex.org/W2163481728","https://openalex.org/W2167380395","https://openalex.org/W2170818583","https://openalex.org/W2175385506","https://openalex.org/W2199695484","https://openalex.org/W2201689894","https://openalex.org/W2232599505","https://openalex.org/W2238012416","https://openalex.org/W2250539671","https://openalex.org/W2252568502","https://openalex.org/W2271754458","https://openalex.org/W2279334880","https://openalex.org/W2283794411","https://openalex.org/W2327182906","https://openalex.org/W2336828812","https://openalex.org/W2338215681","https://openalex.org/W2399809721","https://openalex.org/W2402498701","https://openalex.org/W2408159711","https://openalex.org/W2470282799","https://openalex.org/W2470801200","https://openalex.org/W2473631707","https://openalex.org/W2473953377","https://openalex.org/W2476759866","https://openalex.org/W2480829753","https://openalex.org/W2492028603","https://openalex.org/W2509775353","https://openalex.org/W2509874246","https://openalex.org/W2511569157","https://openalex.org/W2513235972","https://openalex.org/W2513567443","https://openalex.org/W2579163968","https://openalex.org/W2584973635","https://openalex.org/W2587186776","https://openalex.org/W2587588342","https://openalex.org/W2593182764","https://openalex.org/W2595383093","https://openalex.org/W2606915822","https://openalex.org/W2608378705","https://openalex.org/W2616853239","https://openalex.org/W2618698013","https://openalex.org/W2623277795","https://openalex.org/W2625522207","https://openalex.org/W2635877744","https://openalex.org/W2736242246","https://openalex.org/W2740658361","https://openalex.org/W2749459021","https://openalex.org/W2751498160","https://openalex.org/W2752453466","https://openalex.org/W2757079914","https://openalex.org/W2763042654","https://openalex.org/W2765610460","https://openalex.org/W2766599608","https://openalex.org/W2770300757","https://openalex.org/W2772524563","https://openalex.org/W2778131996","https://openalex.org/W2780265514","https://openalex.org/W2782551527","https://openalex.org/W2786426577","https://openalex.org/W2790102940","https://openalex.org/W2797928483","https://openalex.org/W2801626640","https://openalex.org/W2801867656","https://openalex.org/W2803245377","https://openalex.org/W2803340220","https://openalex.org/W2803479625","https://openalex.org/W2803724695","https://openalex.org/W2805661571","https://openalex.org/W2809042973","https://openalex.org/W2810756255","https://openalex.org/W2883250809","https://openalex.org/W2885580646","https://openalex.org/W2891027664","https://openalex.org/W2897080909","https://openalex.org/W2897138703","https://openalex.org/W2897791282","https://openalex.org/W2898146810","https://openalex.org/W2898448050","https://openalex.org/W2899807648","https://openalex.org/W2902555008","https://openalex.org/W2903293883","https://openalex.org/W2911986456","https://openalex.org/W2915459742","https://openalex.org/W2922407153","https://openalex.org/W2939811618","https://openalex.org/W2940996965","https://openalex.org/W2945567049","https://openalex.org/W2949259699","https://openalex.org/W2950114027","https://openalex.org/W2950465744","https://openalex.org/W2950564381","https://openalex.org/W2950704869","https://openalex.org/W2950723166","https://openalex.org/W2950826032","https://openalex.org/W2951608195","https://openalex.org/W2952346338","https://openalex.org/W2962990415","https://openalex.org/W2963813643","https://openalex.org/W2964265365","https://openalex.org/W2964573658","https://openalex.org/W2968536921","https://openalex.org/W2968616686","https://openalex.org/W2969658338","https://openalex.org/W2970098032","https://openalex.org/W2972569409","https://openalex.org/W2973300930","https://openalex.org/W2973312556","https://openalex.org/W2976872283","https://openalex.org/W2981137429","https://openalex.org/W2981279305","https://openalex.org/W2981762194","https://openalex.org/W2982510384","https://openalex.org/W2984255992","https://openalex.org/W2990436921","https://openalex.org/W2990944400","https://openalex.org/W2991600264","https://openalex.org/W2993948503","https://openalex.org/W2995081665","https://openalex.org/W2995849392","https://openalex.org/W2996772158","https://openalex.org/W2997404121","https://openalex.org/W2998932094","https://openalex.org/W3000887181","https://openalex.org/W3001403871","https://openalex.org/W3004378293","https://openalex.org/W3005962315","https://openalex.org/W3007039054","https://openalex.org/W3007485829","https://openalex.org/W3010009109","https://openalex.org/W3012016445","https://openalex.org/W3013120721","https://openalex.org/W3014005122","https://openalex.org/W3014506265","https://openalex.org/W3015370321","https://openalex.org/W3015798850","https://openalex.org/W3020116629","https://openalex.org/W3020732568","https://openalex.org/W3023181423","https://openalex.org/W3024100655","https://openalex.org/W3026606344","https://openalex.org/W3029055906","https://openalex.org/W3029194094","https://openalex.org/W3034712462","https://openalex.org/W3035700080","https://openalex.org/W3036373230","https://openalex.org/W3038121973","https://openalex.org/W3039159245","https://openalex.org/W3044212907","https://openalex.org/W3045990256","https://openalex.org/W3067682183","https://openalex.org/W3081692415","https://openalex.org/W3083839405","https://openalex.org/W3086818971","https://openalex.org/W3087131783","https://openalex.org/W3087424926","https://openalex.org/W3087510731","https://openalex.org/W3087701445","https://openalex.org/W3087819126","https://openalex.org/W3089756407","https://openalex.org/W3093405942","https://openalex.org/W3097237310","https://openalex.org/W3108496856","https://openalex.org/W3109626990","https://openalex.org/W3111496797","https://openalex.org/W3115574477","https://openalex.org/W3119382661","https://openalex.org/W3125658303","https://openalex.org/W3127729088","https://openalex.org/W3129350402","https://openalex.org/W3131093799","https://openalex.org/W3134782704","https://openalex.org/W3135625811","https://openalex.org/W3136535512","https://openalex.org/W3139032411","https://openalex.org/W3147470515","https://openalex.org/W3159928091","https://openalex.org/W3162544196","https://openalex.org/W3167995117","https://openalex.org/W3174716159","https://openalex.org/W3174925725","https://openalex.org/W3175660051","https://openalex.org/W3182913057","https://openalex.org/W3185682422","https://openalex.org/W3188619241","https://openalex.org/W3190858414","https://openalex.org/W3193991572","https://openalex.org/W3194369599","https://openalex.org/W3194399644","https://openalex.org/W3195330678","https://openalex.org/W3198990641","https://openalex.org/W3201528655","https://openalex.org/W3202931255","https://openalex.org/W3203405076","https://openalex.org/W3206568807","https://openalex.org/W3207257668","https://openalex.org/W3208363900","https://openalex.org/W3214358561","https://openalex.org/W3215473475","https://openalex.org/W4200249739","https://openalex.org/W4205143015","https://openalex.org/W4210762403","https://openalex.org/W4213036952","https://openalex.org/W4213224140","https://openalex.org/W4214553676","https://openalex.org/W4221016141","https://openalex.org/W4221018863","https://openalex.org/W4221026353","https://openalex.org/W4221055802","https://openalex.org/W4225552276","https://openalex.org/W4225646954","https://openalex.org/W4281663275","https://openalex.org/W4281698436","https://openalex.org/W4281963872","https://openalex.org/W4285395826","https://openalex.org/W4288734496","https://openalex.org/W4293026694","https://openalex.org/W4294844871","https://openalex.org/W4307561054","https://openalex.org/W4307583934","https://openalex.org/W4307844978","https://openalex.org/W4307936084","https://openalex.org/W4308616057","https://openalex.org/W4309655342","https://openalex.org/W4315480033","https://openalex.org/W4315650359","https://openalex.org/W4316507374","https://openalex.org/W4319966493","https://openalex.org/W4321076925","https://openalex.org/W4366085048","https://openalex.org/W4366603469","https://openalex.org/W4366991602","https://openalex.org/W4367311810","https://openalex.org/W4376610549","https://openalex.org/W4376871110","https://openalex.org/W4377290841","https://openalex.org/W4378782322","https://openalex.org/W4382881322","https://openalex.org/W4382989753","https://openalex.org/W4386086644","https://openalex.org/W4386387605","https://openalex.org/W4386484842","https://openalex.org/W4386499154","https://openalex.org/W4387662402","https://openalex.org/W4387707751","https://openalex.org/W4387966791","https://openalex.org/W4388609874","https://openalex.org/W4388789415","https://openalex.org/W4388821703","https://openalex.org/W4390165762","https://openalex.org/W4390718894","https://openalex.org/W4391825262","https://openalex.org/W4392213218","https://openalex.org/W4392705635","https://openalex.org/W4392797177","https://openalex.org/W4399022907","https://openalex.org/W4399893117","https://openalex.org/W4400115836","https://openalex.org/W4401634292","https://openalex.org/W4402749107","https://openalex.org/W4404733535","https://openalex.org/W4407978765","https://openalex.org/W4410419059","https://openalex.org/W4410510794","https://openalex.org/W4410546893"],"related_works":[],"abstract_inverted_index":{"Clustered":[0],"Regularly":[1],"Interspaced":[2],"Short":[3],"Palindromic":[4],"Repeats":[5],"(CRISPR)-CRISPR":[6],"associated":[7],"protein":[8],"(CRISPR-Cas)":[9],"has":[10,32,86],"emerged":[11],"and":[12,61,67,99,110,136,139,142,154,175,202],"evolved":[13],"as":[14,49,129,131],"a":[15,80,94,173],"revolutionary":[16],"genome":[17,38,167],"editing":[18,50,135,168],"technology,":[19],"transforming":[20],"research":[21],"across":[22],"diverse":[23],"biological":[24],"disciplines.":[25],"Over":[26],"the":[27,41,57,105,111,140,194],"past":[28],"decade,":[29],"this":[30,90],"technology":[31],"unveiled":[33],"numerous":[34],"opportunities":[35],"for":[36,121,133,151,166,196],"precise":[37],"manipulation.":[39],"However,":[40],"processes":[42],"of":[43,77,83,97,107,113,144],"discovering":[44],"Cas":[45],"proteins,":[46],"repurposing":[47],"them":[48],"tools,":[51],"selecting":[52],"appropriate":[53],"candidate":[54],"tool":[55],"from":[56,211],"CRISPR-toolbox,":[58],"designing":[59],"experiments,":[60],"analyzing":[62],"data":[63],"are":[64],"often":[65],"complex":[66],"require":[68],"careful":[69],"consideration.":[70],"To":[71],"support":[72],"researchers":[73,179],"at":[74],"every":[75],"stage":[76],"CRISPR":[78,197],"experimentation,":[79],"wide":[81],"array":[82],"web":[84,159,206],"resources":[85],"been":[87],"developed.":[88],"In":[89],"article,":[91],"we":[92,148],"provide":[93],"comprehensive":[95],"overview":[96],"standalone":[98],"web-based":[100],"tools":[101,120,132,165,184],"that":[102,161],"assist":[103],"in":[104],"identification":[106],"CRISPR-Cas":[108],"systems":[109],"design":[112],"guide":[114],"RNAs":[115],"(gRNAs).":[116],"We":[117],"also":[118],"highlight":[119],"evaluating":[122],"gRNA":[123],"efficiency,":[124],"predicting":[125],"CRISPR-Cas9":[126],"mutation":[127],"profiles,":[128],"well":[130],"base":[134],"prime":[137],"editing,":[138],"analysis":[141],"visualization":[143],"experimental":[145],"results.":[146],"Additionally,":[147],"introduce":[149],"CRISPR-Gateway":[150],"Accessing":[152],"Tools":[153],"Resources":[155],"(CRISPR-GATE),":[156],"an":[157],"all-inclusive":[158],"repository":[160,171,207],"consolidates":[162],"publicly":[163],"available":[164],"research.":[169],"This":[170],"offers":[172],"categorized":[174],"user-friendly":[176],"interface,":[177],"allowing":[178],"to":[180,192],"quickly":[181],"access":[182],"relevant":[183],"based":[185],"on":[186],"their":[187],"specific":[188],"needs.":[189],"CRISPR-GATE":[190],"aims":[191],"streamline":[193],"search":[195],"resources,":[198],"facilitating":[199],"both":[200],"education":[201],"accelerating":[203],"innovation.":[204],"The":[205],"can":[208],"be":[209],"accessed":[210],"https://crispr-gate.daasbioinfromaticsteam.in/.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-11-02T00:00:00"}