{"id":"https://openalex.org/W4413816496","doi":"https://doi.org/10.1093/bib/bbaf440","title":"Deep learning\u2013driven multi-omics analysis: enhancing cancer diagnostics and therapeutics","display_name":"Deep learning\u2013driven multi-omics analysis: enhancing cancer diagnostics and therapeutics","publication_year":2025,"publication_date":"2025-07-01","ids":{"openalex":"https://openalex.org/W4413816496","doi":"https://doi.org/10.1093/bib/bbaf440","pmid":"https://pubmed.ncbi.nlm.nih.gov/40874818"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaf440","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf440","pdf_url":"https://academic.oup.com/bib/article-pdf/26/4/bbaf440/64147839/bbaf440.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bib/article-pdf/26/4/bbaf440/64147839/bbaf440.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025463315","display_name":"Jiayang Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]},{"id":"https://openalex.org/I4210142484","display_name":"Second Affiliated Hospital of Jilin University","ror":"https://ror.org/03x6hbh34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142484"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiayang Zhang","raw_affiliation_strings":["Department of Radiology, The Second Hospital of Jilin University , 218 zigiang Street, Changchun, 130041 ,","NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Second Hospital of Jilin University , 218 zigiang Street, Changchun, 130041 ,","institution_ids":["https://openalex.org/I4210142484"]},{"raw_affiliation_string":"NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102702104","display_name":"Yilin Che","orcid":null},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yilin Che","raw_affiliation_strings":["NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,"],"affiliations":[{"raw_affiliation_string":"NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034487315","display_name":"Rongrong Liu","orcid":"https://orcid.org/0009-0002-8581-0311"},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rongrong Liu","raw_affiliation_strings":["NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,"],"affiliations":[{"raw_affiliation_string":"NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100429174","display_name":"Zhicheng Wang","orcid":"https://orcid.org/0000-0002-7617-3165"},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhicheng Wang","raw_affiliation_strings":["NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,"],"affiliations":[{"raw_affiliation_string":"NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University , 1163 Xinmin Street, Changchun, 130021 ,","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113105971","display_name":"Weiwu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210142484","display_name":"Second Affiliated Hospital of Jilin University","ror":"https://ror.org/03x6hbh34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142484"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiwu Liu","raw_affiliation_strings":["Department of Radiology, The Second Hospital of Jilin University , 218 zigiang Street, Changchun, 130041 ,"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Second Hospital of Jilin University , 218 zigiang Street, Changchun, 130041 ,","institution_ids":["https://openalex.org/I4210142484"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5025463315"],"corresponding_institution_ids":["https://openalex.org/I194450716","https://openalex.org/I4210142484"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":26.3789,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.99790156,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"26","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6588347554206848},{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.6090953350067139},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.608980655670166},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5282266139984131},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.508955717086792},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.49313539266586304},{"id":"https://openalex.org/keywords/epigenomics","display_name":"Epigenomics","score":0.48503607511520386},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.44460174441337585},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.43617919087409973},{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.43116945028305054},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"Personalized medicine","score":0.4260116517543793},{"id":"https://openalex.org/keywords/big-data","display_name":"Big data","score":0.4247363209724426},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.4182387888431549},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.41593340039253235},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3366851508617401},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2647257447242737},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14094772934913635},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1374790370464325},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.08386543393135071},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.08111277222633362},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.07745826244354248}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6588347554206848},{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.6090953350067139},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.608980655670166},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5282266139984131},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.508955717086792},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.49313539266586304},{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.48503607511520386},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.44460174441337585},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43617919087409973},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.43116945028305054},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.4260116517543793},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.4247363209724426},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.4182387888431549},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.41593340039253235},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3366851508617401},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2647257447242737},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14094772934913635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1374790370464325},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.08386543393135071},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.08111277222633362},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07745826244354248},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbaf440","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf440","pdf_url":"https://academic.oup.com/bib/article-pdf/26/4/bbaf440/64147839/bbaf440.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:40874818","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40874818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12392270","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12392270","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbaf440","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf440","pdf_url":"https://academic.oup.com/bib/article-pdf/26/4/bbaf440/64147839/bbaf440.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6235421903","display_name":null,"funder_award_id":"YDZJ202401200ZYTS","funder_id":"https://openalex.org/F4320335953","funder_display_name":"Jilin Scientific and Technological Development Program"},{"id":"https://openalex.org/G8207580308","display_name":null,"funder_award_id":"20240101275JC","funder_id":"https://openalex.org/F4320335953","funder_display_name":"Jilin Scientific and Technological Development Program"}],"funders":[{"id":"https://openalex.org/F4320335953","display_name":"Jilin Scientific and Technological Development Program","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413816496.pdf","grobid_xml":"https://content.openalex.org/works/W4413816496.grobid-xml"},"referenced_works_count":229,"referenced_works":["https://openalex.org/W117085007","https://openalex.org/W198304791","https://openalex.org/W1222412097","https://openalex.org/W1972618510","https://openalex.org/W1981509058","https://openalex.org/W2016060560","https://openalex.org/W2032448018","https://openalex.org/W2037837681","https://openalex.org/W2044532561","https://openalex.org/W2048333869","https://openalex.org/W2067123389","https://openalex.org/W2068767807","https://openalex.org/W2084123824","https://openalex.org/W2092390808","https://openalex.org/W2093582064","https://openalex.org/W2115703678","https://openalex.org/W2128739912","https://openalex.org/W2140600399","https://openalex.org/W2147426864","https://openalex.org/W2161863487","https://openalex.org/W2167898988","https://openalex.org/W2231968663","https://openalex.org/W2282821441","https://openalex.org/W2346687813","https://openalex.org/W2520784563","https://openalex.org/W2585057233","https://openalex.org/W2589504386","https://openalex.org/W2602182553","https://openalex.org/W2617990239","https://openalex.org/W2735575534","https://openalex.org/W2742487486","https://openalex.org/W2745541172","https://openalex.org/W2757251151","https://openalex.org/W2763355946","https://openalex.org/W2767290858","https://openalex.org/W2772851294","https://openalex.org/W2783674487","https://openalex.org/W2887378427","https://openalex.org/W2892221324","https://openalex.org/W2903458588","https://openalex.org/W2915848182","https://openalex.org/W2919115771","https://openalex.org/W2920679031","https://openalex.org/W2940612399","https://openalex.org/W2944851425","https://openalex.org/W2949740511","https://openalex.org/W2951209146","https://openalex.org/W2951890476","https://openalex.org/W2951934944","https://openalex.org/W2964248614","https://openalex.org/W2969259882","https://openalex.org/W2975441595","https://openalex.org/W2978882452","https://openalex.org/W2982274340","https://openalex.org/W2996227376","https://openalex.org/W3003210365","https://openalex.org/W3004053956","https://openalex.org/W3009535750","https://openalex.org/W3013823153","https://openalex.org/W3014261926","https://openalex.org/W3016487203","https://openalex.org/W3024761859","https://openalex.org/W3025036301","https://openalex.org/W3030432638","https://openalex.org/W3036962145","https://openalex.org/W3040871428","https://openalex.org/W3041378136","https://openalex.org/W3043602140","https://openalex.org/W3043835773","https://openalex.org/W3044262883","https://openalex.org/W3044540004","https://openalex.org/W3044996171","https://openalex.org/W3049084893","https://openalex.org/W3085362629","https://openalex.org/W3090967605","https://openalex.org/W3091925510","https://openalex.org/W3093817012","https://openalex.org/W3096958321","https://openalex.org/W3102627954","https://openalex.org/W3116278528","https://openalex.org/W3118741877","https://openalex.org/W3120795911","https://openalex.org/W3125147070","https://openalex.org/W3125330584","https://openalex.org/W3127915613","https://openalex.org/W3128180131","https://openalex.org/W3129704704","https://openalex.org/W3132686583","https://openalex.org/W3133171723","https://openalex.org/W3134111171","https://openalex.org/W3138985726","https://openalex.org/W3143329879","https://openalex.org/W3152926200","https://openalex.org/W3162293114","https://openalex.org/W3162350134","https://openalex.org/W3163443268","https://openalex.org/W3166025287","https://openalex.org/W3170986249","https://openalex.org/W3171464509","https://openalex.org/W3172005333","https://openalex.org/W3172801005","https://openalex.org/W3176714582","https://openalex.org/W3178738300","https://openalex.org/W3181637650","https://openalex.org/W3181660183","https://openalex.org/W3193417673","https://openalex.org/W3193672170","https://openalex.org/W3194492341","https://openalex.org/W3195038684","https://openalex.org/W3197417533","https://openalex.org/W3201700496","https://openalex.org/W3204312334","https://openalex.org/W3205076722","https://openalex.org/W3206680674","https://openalex.org/W3206783061","https://openalex.org/W3212967789","https://openalex.org/W4205550832","https://openalex.org/W4206042814","https://openalex.org/W4206964597","https://openalex.org/W4206973567","https://openalex.org/W4211042748","https://openalex.org/W4211119455","https://openalex.org/W4213143350","https://openalex.org/W4220807984","https://openalex.org/W4220903131","https://openalex.org/W4220927627","https://openalex.org/W4220985197","https://openalex.org/W4221049186","https://openalex.org/W4224215508","https://openalex.org/W4224282293","https://openalex.org/W4224947610","https://openalex.org/W4225108987","https://openalex.org/W4225328993","https://openalex.org/W4225525963","https://openalex.org/W4226205491","https://openalex.org/W4229001565","https://openalex.org/W4256559379","https://openalex.org/W4283319170","https://openalex.org/W4284676349","https://openalex.org/W4285404371","https://openalex.org/W4287447409","https://openalex.org/W4291021272","https://openalex.org/W4291286390","https://openalex.org/W4293199663","https://openalex.org/W4295242275","https://openalex.org/W4296038132","https://openalex.org/W4297235583","https://openalex.org/W4298168912","https://openalex.org/W4306385613","https://openalex.org/W4307727914","https://openalex.org/W4309334544","https://openalex.org/W4313583499","https://openalex.org/W4315489512","https://openalex.org/W4318189471","https://openalex.org/W4318478374","https://openalex.org/W4318561805","https://openalex.org/W4364860989","https://openalex.org/W4366091323","https://openalex.org/W4366551165","https://openalex.org/W4375947188","https://openalex.org/W4377226745","https://openalex.org/W4378348133","https://openalex.org/W4379521442","https://openalex.org/W4380154190","https://openalex.org/W4381249426","https://openalex.org/W4381614877","https://openalex.org/W4385231026","https://openalex.org/W4385648851","https://openalex.org/W4385796046","https://openalex.org/W4386086592","https://openalex.org/W4386481874","https://openalex.org/W4386698011","https://openalex.org/W4387117073","https://openalex.org/W4387422369","https://openalex.org/W4387966354","https://openalex.org/W4388129865","https://openalex.org/W4388334159","https://openalex.org/W4388511622","https://openalex.org/W4388834713","https://openalex.org/W4388849796","https://openalex.org/W4389159422","https://openalex.org/W4389196731","https://openalex.org/W4390613477","https://openalex.org/W4390794039","https://openalex.org/W4391013397","https://openalex.org/W4391432012","https://openalex.org/W4392393059","https://openalex.org/W4392874417","https://openalex.org/W4392963090","https://openalex.org/W4393132144","https://openalex.org/W4393221085","https://openalex.org/W4395671816","https://openalex.org/W4395954533","https://openalex.org/W4396574532","https://openalex.org/W4397009294","https://openalex.org/W4399037157","https://openalex.org/W4399814511","https://openalex.org/W4399820395","https://openalex.org/W4400061223","https://openalex.org/W4400285718","https://openalex.org/W4400294055","https://openalex.org/W4400576356","https://openalex.org/W4400981456","https://openalex.org/W4401755665","https://openalex.org/W4402466851","https://openalex.org/W4403189496","https://openalex.org/W4403466400","https://openalex.org/W4403707314","https://openalex.org/W4403946353","https://openalex.org/W4404020957","https://openalex.org/W4404234503","https://openalex.org/W4404360535","https://openalex.org/W4405496853","https://openalex.org/W4405562281","https://openalex.org/W4405783659","https://openalex.org/W4407451996","https://openalex.org/W4408069179","https://openalex.org/W4409118693","https://openalex.org/W4409212286","https://openalex.org/W4409214755","https://openalex.org/W4409286450","https://openalex.org/W4410334387","https://openalex.org/W4410812508","https://openalex.org/W4411172774","https://openalex.org/W4411274597","https://openalex.org/W4411351183","https://openalex.org/W4411669435","https://openalex.org/W4412785341","https://openalex.org/W4412825760"],"related_works":["https://openalex.org/W3082935376","https://openalex.org/W2991569435","https://openalex.org/W3047998978","https://openalex.org/W4399651953","https://openalex.org/W4386960999","https://openalex.org/W2899657781","https://openalex.org/W4322484660","https://openalex.org/W2788286722","https://openalex.org/W3193951088","https://openalex.org/W2042445733"],"abstract_inverted_index":{"Artificial":[0],"intelligence":[1],"(AI)":[2],"excels":[3,56],"at":[4,57],"efficiently":[5],"processing":[6,97],"large":[7],"volumes":[8],"of":[9,20,31,38,43,48,73,90,106,121,149,174,215],"data":[10,75,96,133,169],"and":[11,61,114,123,127,143,152,163,182,191],"extracting":[12],"valuable":[13],"insights.":[14],"Deep":[15],"Learning":[16],"(DL),":[17],"a":[18,82,104,172],"subfield":[19],"AI,":[21],"utilizes":[22],"multi-layer":[23],"neural":[24,35],"network":[25,36],"algorithms":[26],"to":[27,93,207],"analyze":[28],"various":[29,160],"types":[30],"data,":[32],"mimicking":[33],"the":[34,39,44,71,213],"architecture":[37],"human":[40],"brain.":[41],"One":[42],"most":[45],"prominent":[46],"features":[47],"DL":[49,99,130,161,175,195],"is":[50,100],"its":[51,94,184],"end-to-end":[52],"learning":[53],"mechanism,":[54],"which":[55],"automatic":[58],"feature":[59],"extraction":[60],"pattern":[62],"recognition":[63],"in":[64,85,166,177,186,204],"data.":[65],"As":[66,194],"multi-omics":[67,179],"technologies":[68],"rapidly":[69],"evolve,":[70],"volume":[72],"omics":[74],"from":[76,134],"cancer":[77,107,150,178,205,216],"samples":[78],"has":[79],"surged,":[80],"presenting":[81],"significant":[83],"challenge":[84],"managing":[86],"this":[87],"vast":[88],"amount":[89],"information.":[91],"Due":[92],"strong":[95],"capabilities,":[98],"increasingly":[101],"applied":[102],"across":[103],"range":[105],"research":[108,181,206],"areas,":[109],"such":[110,136],"as":[111,137],"early":[112,187],"detection":[113],"screening,":[115],"diagnosis,":[116,189],"molecular":[117],"subtype":[118],"classification,":[119,190],"discovery":[120],"biomarkers,":[122],"predicting":[124],"patient":[125],"prognosis":[126,192],"treatment":[128,155],"responses.":[129],"integrates":[131],"high-dimensional":[132],"fields":[135],"genomics,":[138],"epigenomics,":[139],"transcriptomics,":[140],"proteomics,":[141],"radiomics,":[142],"single-cell":[144],"omics,":[145],"enhancing":[146],"our":[147],"understanding":[148],"development":[151],"advancing":[153],"personalized":[154],"approaches.":[156],"This":[157],"paper":[158],"reviews":[159],"models":[162,196],"their":[164,202],"roles":[165],"analyzing":[167],"complex":[168],"patterns,":[170],"providing":[171],"review":[173],"applications":[176],"analysis":[180],"emphasizing":[183],"potential":[185],"detection,":[188],"prediction.":[193],"are":[197],"introduced":[198],"continuously,":[199],"we":[200],"expect":[201],"application":[203],"become":[208],"more":[209],"extensive,":[210],"thus":[211],"propelling":[212],"advancement":[214],"medicine.":[217]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":15}],"updated_date":"2026-04-03T22:45:19.894376","created_date":"2025-10-10T00:00:00"}