{"id":"https://openalex.org/W4410842897","doi":"https://doi.org/10.1093/bib/bbaf132","title":"I-SVVS: integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data","display_name":"I-SVVS: integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4410842897","doi":"https://doi.org/10.1093/bib/bbaf132","pmid":"https://pubmed.ncbi.nlm.nih.gov/40441709"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaf132","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf132","pdf_url":"https://academic.oup.com/bib/article-pdf/26/3/bbaf132/63397901/bbaf132.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bib/article-pdf/26/3/bbaf132/63397901/bbaf132.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043380578","display_name":"Tung Dang","orcid":"https://orcid.org/0000-0002-4974-9632"},"institutions":[{"id":"https://openalex.org/I127317711","display_name":"Tokyo University of Agriculture","ror":"https://ror.org/05crbcr45","country_code":"JP","type":"education","lineage":["https://openalex.org/I127317711"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tung Dang","raw_affiliation_strings":["Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","Laboratory for Medical Science Mathematics , Department of Biological Sciences, School of Science, 4F, Faculty of Science Building 3, , 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 ,","The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","The University of Tokyo , Department of Biological Sciences, School of Science, 4F, Faculty of Science Building 3, , 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 ,"],"raw_orcid":"https://orcid.org/0000-0002-4974-9632","affiliations":[{"raw_affiliation_string":"Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":[]},{"raw_affiliation_string":"Laboratory for Medical Science Mathematics , Department of Biological Sciences, School of Science, 4F, Faculty of Science Building 3, , 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 ,","institution_ids":[]},{"raw_affiliation_string":"The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":["https://openalex.org/I127317711","https://openalex.org/I74801974"]},{"raw_affiliation_string":"The University of Tokyo , Department of Biological Sciences, School of Science, 4F, Faculty of Science Building 3, , 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 ,","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023170300","display_name":"Yushiro Fuji","orcid":"https://orcid.org/0009-0004-4465-7175"},"institutions":[{"id":"https://openalex.org/I114171174","display_name":"Tsurumi University","ror":"https://ror.org/04j8wth34","country_code":"JP","type":"education","lineage":["https://openalex.org/I114171174"]},{"id":"https://openalex.org/I4210100240","display_name":"RIKEN Center for Sustainable Resource Science","ror":"https://ror.org/010rf2m76","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210100240","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yushiro Fuji","raw_affiliation_strings":["RIKEN Center for Sustainable Resource Science, RIKEN , ,","Tsurumi-ku, Yokohama, 2-1 HirosawaWako, Saitama 351-0198 , ,"],"raw_orcid":"https://orcid.org/0009-0004-4465-7175","affiliations":[{"raw_affiliation_string":"RIKEN Center for Sustainable Resource Science, RIKEN , ,","institution_ids":["https://openalex.org/I4210100240"]},{"raw_affiliation_string":"Tsurumi-ku, Yokohama, 2-1 HirosawaWako, Saitama 351-0198 , ,","institution_ids":["https://openalex.org/I114171174"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003955951","display_name":"Kie Kumaishi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kie Kumaishi","raw_affiliation_strings":["RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061655472","display_name":"Erika Usui","orcid":null},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Erika Usui","raw_affiliation_strings":["RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014133803","display_name":"Shungo Kobori","orcid":"https://orcid.org/0000-0003-4995-5847"},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shungo Kobori","raw_affiliation_strings":["RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082458553","display_name":"Takumi Sato","orcid":"https://orcid.org/0000-0003-4277-0583"},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takumi Sato","raw_affiliation_strings":["RIKEN BioResource Research Center , RIKEN, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center , RIKEN, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084263345","display_name":"Megumi Narukawa","orcid":"https://orcid.org/0000-0001-8897-1802"},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Megumi Narukawa","raw_affiliation_strings":["RIKEN BioResource Research Center , RIKEN, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center , RIKEN, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032186893","display_name":"Yusuke Toda","orcid":"https://orcid.org/0000-0002-9462-6412"},"institutions":[{"id":"https://openalex.org/I127317711","display_name":"Tokyo University of Agriculture","ror":"https://ror.org/05crbcr45","country_code":"JP","type":"education","lineage":["https://openalex.org/I127317711"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yusuke Toda","raw_affiliation_strings":["Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, The University of Tokyo, 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,"],"raw_orcid":"https://orcid.org/0000-0002-9462-6412","affiliations":[{"raw_affiliation_string":"Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, The University of Tokyo, 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":["https://openalex.org/I127317711","https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028396335","display_name":"Kengo Sakurai","orcid":"https://orcid.org/0000-0001-7773-289X"},"institutions":[{"id":"https://openalex.org/I127317711","display_name":"Tokyo University of Agriculture","ror":"https://ror.org/05crbcr45","country_code":"JP","type":"education","lineage":["https://openalex.org/I127317711"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kengo Sakurai","raw_affiliation_strings":["Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,"],"raw_orcid":"https://orcid.org/0000-0001-7773-289X","affiliations":[{"raw_affiliation_string":"Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":[]},{"raw_affiliation_string":"The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":["https://openalex.org/I127317711","https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067913388","display_name":"Yuji Yamasaki","orcid":"https://orcid.org/0000-0001-8943-3256"},"institutions":[{"id":"https://openalex.org/I4588055","display_name":"Tottori University","ror":"https://ror.org/024yc3q36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4588055"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Yamasaki","raw_affiliation_strings":["Arid Land Research Center, Tottori University , 1390 Hamasaka, Tottori 680-0001 ,"],"raw_orcid":"https://orcid.org/0000-0001-8943-3256","affiliations":[{"raw_affiliation_string":"Arid Land Research Center, Tottori University , 1390 Hamasaka, Tottori 680-0001 ,","institution_ids":["https://openalex.org/I4588055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068549081","display_name":"Hisashi Tsujimoto","orcid":"https://orcid.org/0000-0003-0203-0759"},"institutions":[{"id":"https://openalex.org/I4588055","display_name":"Tottori University","ror":"https://ror.org/024yc3q36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4588055"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisashi Tsujimoto","raw_affiliation_strings":["Arid Land Research Center, Tottori University , 1390 Hamasaka, Tottori 680-0001 ,"],"raw_orcid":"https://orcid.org/0000-0003-0203-0759","affiliations":[{"raw_affiliation_string":"Arid Land Research Center, Tottori University , 1390 Hamasaka, Tottori 680-0001 ,","institution_ids":["https://openalex.org/I4588055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038913847","display_name":"Masami Yokota Hirai","orcid":"https://orcid.org/0000-0003-0802-6208"},"institutions":[{"id":"https://openalex.org/I4210100240","display_name":"RIKEN Center for Sustainable Resource Science","ror":"https://ror.org/010rf2m76","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210100240","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masami Yokota Hirai","raw_affiliation_strings":["RIKEN Center for Sustainable Resource Science, RIKEN , Tsurumi-ku, Yokohama, 2-1 HirosawaWako, Saitama 351-0198 ,"],"raw_orcid":"https://orcid.org/0000-0003-0802-6208","affiliations":[{"raw_affiliation_string":"RIKEN Center for Sustainable Resource Science, RIKEN , Tsurumi-ku, Yokohama, 2-1 HirosawaWako, Saitama 351-0198 ,","institution_ids":["https://openalex.org/I4210100240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002040196","display_name":"Yasunori Ichihashi","orcid":"https://orcid.org/0000-0003-1935-4397"},"institutions":[{"id":"https://openalex.org/I4210096362","display_name":"RIKEN BioResource Research Center","ror":"https://ror.org/00s05em53","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210096362","https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunori Ichihashi","raw_affiliation_strings":["RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,"],"raw_orcid":"https://orcid.org/0000-0003-1935-4397","affiliations":[{"raw_affiliation_string":"RIKEN BioResource Research Center, RIKEN , 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074 ,","institution_ids":["https://openalex.org/I4210096362"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084168371","display_name":"Hiroyoshi Iwata","orcid":"https://orcid.org/0000-0002-6747-7036"},"institutions":[{"id":"https://openalex.org/I127317711","display_name":"Tokyo University of Agriculture","ror":"https://ror.org/05crbcr45","country_code":"JP","type":"education","lineage":["https://openalex.org/I127317711"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyoshi Iwata","raw_affiliation_strings":["Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,"],"raw_orcid":"https://orcid.org/0000-0002-6747-7036","affiliations":[{"raw_affiliation_string":"Graduate School of Agricultural and Life Sciences , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":[]},{"raw_affiliation_string":"The University of Tokyo , Building 1 #327, Department of Agriculture, , 1-1-1, Yayoi, Bunkyo, Tokyo 113-8657 ,","institution_ids":["https://openalex.org/I127317711","https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5043380578"],"corresponding_institution_ids":["https://openalex.org/I127317711","https://openalex.org/I74801974"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":3.5568,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.92731752,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"26","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbiome","display_name":"Microbiome","score":0.7835339903831482},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6728235483169556},{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.6343907117843628},{"id":"https://openalex.org/keywords/metabolome","display_name":"Metabolome","score":0.5841852426528931},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5781928300857544},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5719898343086243},{"id":"https://openalex.org/keywords/mixture-model","display_name":"Mixture model","score":0.44775551557540894},{"id":"https://openalex.org/keywords/metabolomics","display_name":"Metabolomics","score":0.44535496830940247},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.4406794011592865},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.43598711490631104},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4288233518600464},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.42451193928718567},{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.41776642203330994},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.41339367628097534},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4107295274734497},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2994217872619629},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28361278772354126},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2745564579963684},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.25693121552467346}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.7835339903831482},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6728235483169556},{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.6343907117843628},{"id":"https://openalex.org/C135870905","wikidata":"https://www.wikidata.org/wiki/Q903667","display_name":"Metabolome","level":3,"score":0.5841852426528931},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5781928300857544},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5719898343086243},{"id":"https://openalex.org/C61224824","wikidata":"https://www.wikidata.org/wiki/Q2260434","display_name":"Mixture model","level":2,"score":0.44775551557540894},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.44535496830940247},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.4406794011592865},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.43598711490631104},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4288233518600464},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.42451193928718567},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.41776642203330994},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41339367628097534},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4107295274734497},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2994217872619629},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28361278772354126},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2745564579963684},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.25693121552467346},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013025","descriptor_name":"Glycine max","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbaf132","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf132","pdf_url":"https://academic.oup.com/bib/article-pdf/26/3/bbaf132/63397901/bbaf132.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:40441709","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40441709","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12122083","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12122083","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbaf132","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf132","pdf_url":"https://academic.oup.com/bib/article-pdf/26/3/bbaf132/63397901/bbaf132.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.699999988079071,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G5535353859","display_name":null,"funder_award_id":"JP21J21850","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6691088997","display_name":null,"funder_award_id":"JPMJMI120C7","funder_id":"https://openalex.org/F4320338243","funder_display_name":"JST-Mirai Program"},{"id":"https://openalex.org/G6718509927","display_name":null,"funder_award_id":"CREST","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320338075","display_name":"Core Research for Evolutional Science and Technology","ror":"https://ror.org/00097mb19"},{"id":"https://openalex.org/F4320338115","display_name":"Advanced Low Carbon Technology Research and Development Program","ror":null},{"id":"https://openalex.org/F4320338243","display_name":"JST-Mirai Program","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410842897.pdf","grobid_xml":"https://content.openalex.org/works/W4410842897.grobid-xml"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W86354743","https://openalex.org/W1989387811","https://openalex.org/W1993399595","https://openalex.org/W2000619947","https://openalex.org/W2006465310","https://openalex.org/W2023461603","https://openalex.org/W2033996602","https://openalex.org/W2050551770","https://openalex.org/W2053801811","https://openalex.org/W2056279562","https://openalex.org/W2060485250","https://openalex.org/W2074856830","https://openalex.org/W2083561733","https://openalex.org/W2095763169","https://openalex.org/W2099266276","https://openalex.org/W2119890355","https://openalex.org/W2128743534","https://openalex.org/W2158266063","https://openalex.org/W2158485828","https://openalex.org/W2161439484","https://openalex.org/W2171231777","https://openalex.org/W2225156818","https://openalex.org/W2336842442","https://openalex.org/W2395461901","https://openalex.org/W2519794569","https://openalex.org/W2531542945","https://openalex.org/W2558792200","https://openalex.org/W2624135745","https://openalex.org/W2793810666","https://openalex.org/W2805063718","https://openalex.org/W2943042213","https://openalex.org/W2947189704","https://openalex.org/W2949004447","https://openalex.org/W2949127449","https://openalex.org/W2977433364","https://openalex.org/W2981638144","https://openalex.org/W2982359249","https://openalex.org/W2995755921","https://openalex.org/W3019834965","https://openalex.org/W3033466752","https://openalex.org/W3048805481","https://openalex.org/W3118724893","https://openalex.org/W3121407008","https://openalex.org/W3128111360","https://openalex.org/W3138504832","https://openalex.org/W3147783644","https://openalex.org/W3154924840","https://openalex.org/W3173687967","https://openalex.org/W3192776824","https://openalex.org/W3200426832","https://openalex.org/W4200576432","https://openalex.org/W4210506197","https://openalex.org/W4213262106","https://openalex.org/W4214838518","https://openalex.org/W4280587540","https://openalex.org/W4289885625","https://openalex.org/W4294562888","https://openalex.org/W4306411778","https://openalex.org/W4309829241","https://openalex.org/W4312203488","https://openalex.org/W4315631538","https://openalex.org/W4315647119","https://openalex.org/W4316015744","https://openalex.org/W4318542633","https://openalex.org/W4319593351","https://openalex.org/W4327713018","https://openalex.org/W4378070125","https://openalex.org/W4380082978","https://openalex.org/W4387100260","https://openalex.org/W4388820458","https://openalex.org/W4393031641","https://openalex.org/W4399793343","https://openalex.org/W6684578138"],"related_works":["https://openalex.org/W1996644818","https://openalex.org/W1965468642","https://openalex.org/W2093500216","https://openalex.org/W2053588008","https://openalex.org/W3101161779","https://openalex.org/W423371831","https://openalex.org/W2916376502","https://openalex.org/W2777729175","https://openalex.org/W2260452057","https://openalex.org/W4295779760"],"abstract_inverted_index":{"High-dimensional":[0],"multi-omics":[1,37,44,144],"microbiome":[2,45,76,102,145,157,191,213],"data":[3,46,103],"play":[4],"an":[5,67,95,105],"important":[6],"role":[7],"in":[8,18,143,221,243],"elucidating":[9],"microbial":[10],"community":[11],"interactions":[12],"with":[13,210,230,235],"their":[14],"hosts":[15],"and":[16,21,104,126,152,158,176,193,215,232],"environment":[17],"critical":[19,138],"diseases":[20],"ecological":[22],"changes.":[23],"Although":[24],"Bayesian":[25,84],"clustering":[26,124,132],"methods":[27,182],"have":[28],"recently":[29],"been":[30,48],"used":[31,161],"for":[32,74,87,101,110,239],"the":[33,119,123,128,131,164,200,204],"integrated":[34,156],"analysis":[35,202],"of":[36,69,90,122,130,140,166,203],"data,":[38,92],"no":[39],"method":[40],"designed":[41],"to":[42,117,162,180,227],"analyze":[43],"has":[47],"proposed.":[49],"In":[50],"this":[51,240],"study,":[52],"we":[53],"propose":[54],"a":[55,82,137],"novel":[56],"framework":[57],"called":[58],"integrative":[59],"stochastic":[60,70],"variational":[61,71],"variable":[62,72],"selection":[63,73],"(I-SVVS),":[64],"which":[65],"is":[66,115,245],"extension":[68],"high-dimensional":[75],"data.":[77,112,146],"The":[78,168,237],"I-SVVS":[79,135,172],"approach":[80,114],"addresses":[81],"specific":[83],"mixture":[85,99,108],"model":[86,100,109],"each":[88,196],"type":[89],"omics":[91],"such":[93],"as":[94],"infinite":[96,106],"Dirichlet":[97],"multinomial":[98],"Gaussian":[107],"metabolomic":[111],"This":[113],"expected":[116],"reduce":[118],"computational":[120,201],"time":[121],"process":[125],"improve":[127],"accuracy":[129,175],"results.":[133],"Additionally,":[134],"identifies":[136],"set":[139,155],"representative":[141],"variables":[142],"Three":[147],"datasets":[148],"from":[149],"soybean,":[150],"mice,":[151],"humans":[153],"(each":[154],"metabolome)":[159],"were":[160],"demonstrate":[163],"potential":[165],"I-SVVS.":[167],"results":[169],"indicate":[170],"that":[171],"achieved":[173],"improved":[174],"faster":[177],"computation":[178],"compared":[179,226],"existing":[181],"across":[183],"all":[184],"test":[185],"datasets.":[186],"It":[187],"effectively":[188],"identified":[189],"key":[190],"species":[192,214],"metabolites":[194],"characterizing":[195],"cluster.":[197],"For":[198],"instance,":[199],"soybean":[205],"dataset,":[206],"including":[207],"377":[208],"samples":[209],"16":[211],"943":[212],"265":[216],"metabolome":[217],"features,":[218],"was":[219],"completed":[220],"2.18":[222],"hours":[223],"using":[224],"I-SVVS,":[225],"2.35":[228],"days":[229,234],"Clusternomics":[231],"1.12":[233],"iClusterPlus.":[236],"software":[238],"analysis,":[241],"written":[242],"Python,":[244],"freely":[246],"available":[247],"at":[248],"https://github.com/tungtokyo1108/I-SVVS.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}