{"id":"https://openalex.org/W4407783240","doi":"https://doi.org/10.1093/bib/bbaf062","title":"CSGDN: contrastive signed graph diffusion network for predicting crop gene\u2013phenotype associations","display_name":"CSGDN: contrastive signed graph diffusion network for predicting crop gene\u2013phenotype associations","publication_year":2024,"publication_date":"2024-11-22","ids":{"openalex":"https://openalex.org/W4407783240","doi":"https://doi.org/10.1093/bib/bbaf062","pmid":"https://pubmed.ncbi.nlm.nih.gov/39976387"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaf062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf062","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbaf062","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101136348","display_name":"Yiru Pan","orcid":null},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":true,"raw_author_name":"Yiru Pan","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114245464","display_name":"Xingyu Ji","orcid":null},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Xingyu Ji","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112145292","display_name":"Jin Jong You","orcid":"https://orcid.org/0000-0001-6569-1955"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Jiaqi You","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062380757","display_name":"Lu Li","orcid":null},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Lu Li","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101653535","display_name":"Zhenping Liu","orcid":"https://orcid.org/0000-0002-3046-8005"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Zhenping Liu","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100772315","display_name":"Xianlong Zhang","orcid":"https://orcid.org/0000-0002-7703-524X"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Xianlong Zhang","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100759399","display_name":"Zeyu Zhang","orcid":"https://orcid.org/0000-0002-2376-6151"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Zeyu Zhang","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013257553","display_name":"Maojun Wang","orcid":"https://orcid.org/0000-0002-4791-3742"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4210156466","display_name":"Institute of Crop Science","ror":"https://ror.org/053g6zg46","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1323638106","https://openalex.org/I4210156466"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Maojun Wang","raw_affiliation_strings":["Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,"],"affiliations":[{"raw_affiliation_string":"Hubei Hongshan Laboratory, Huazhong Agricultural University , , 430070 Hubei ,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"National Key Laboratory of Crop Genetic Improvement , , 430070 Hubei ,","institution_ids":["https://openalex.org/I4210156466"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5101136348"],"corresponding_institution_ids":["https://openalex.org/I204823248","https://openalex.org/I4210156466"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":0.6826,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.71482893,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9775999784469604,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9616000056266785,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.669014573097229},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.5048054456710815},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.48661717772483826},{"id":"https://openalex.org/keywords/node","display_name":"Node (physics)","score":0.456814169883728},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.44278237223625183},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3760662376880646},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.37066376209259033},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.36047255992889404},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3453497290611267},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3326120376586914},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.30370619893074036},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24175500869750977},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2142713963985443}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.669014573097229},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.5048054456710815},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.48661717772483826},{"id":"https://openalex.org/C62611344","wikidata":"https://www.wikidata.org/wiki/Q1062658","display_name":"Node (physics)","level":2,"score":0.456814169883728},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.44278237223625183},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3760662376880646},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.37066376209259033},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.36047255992889404},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3453497290611267},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3326120376586914},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.30370619893074036},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24175500869750977},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2142713963985443},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003368","descriptor_name":"Gossypium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003368","descriptor_name":"Gossypium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003368","descriptor_name":"Gossypium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003368","descriptor_name":"Gossypium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018556","descriptor_name":"Crops, Agricultural","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbaf062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf062","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39976387","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39976387","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11840565","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11840565","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbaf062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf062","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1396155800","display_name":null,"funder_award_id":"32170645","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6574541588","display_name":null,"funder_award_id":"2021YFF1000900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7129951821","display_name":null,"funder_award_id":"W2411020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W1854214752","https://openalex.org/W1993494458","https://openalex.org/W2073836327","https://openalex.org/W2079927753","https://openalex.org/W2110035718","https://openalex.org/W2141119617","https://openalex.org/W2142678478","https://openalex.org/W2236822143","https://openalex.org/W2259938310","https://openalex.org/W2264585211","https://openalex.org/W2328393125","https://openalex.org/W2415027247","https://openalex.org/W2488133945","https://openalex.org/W2553123256","https://openalex.org/W2555614465","https://openalex.org/W2555897561","https://openalex.org/W2583103488","https://openalex.org/W2584855799","https://openalex.org/W2621699315","https://openalex.org/W2725988230","https://openalex.org/W2729286457","https://openalex.org/W2800156222","https://openalex.org/W2801006204","https://openalex.org/W2887092413","https://openalex.org/W2902012935","https://openalex.org/W2934861239","https://openalex.org/W2944540884","https://openalex.org/W2964015378","https://openalex.org/W2969257470","https://openalex.org/W2973140148","https://openalex.org/W2997638284","https://openalex.org/W3033039844","https://openalex.org/W3036319490","https://openalex.org/W3040208280","https://openalex.org/W3111720209","https://openalex.org/W3133752693","https://openalex.org/W3175507592","https://openalex.org/W3202551657","https://openalex.org/W3208007380","https://openalex.org/W3213472577","https://openalex.org/W3214714406","https://openalex.org/W4200432712","https://openalex.org/W4205306822","https://openalex.org/W4288902530","https://openalex.org/W4292366917","https://openalex.org/W4297733535","https://openalex.org/W4306765586","https://openalex.org/W4310766443","https://openalex.org/W4322760503","https://openalex.org/W4360609442","https://openalex.org/W4367046596","https://openalex.org/W4384652088","https://openalex.org/W4385245566","https://openalex.org/W4385515013","https://openalex.org/W4386220204","https://openalex.org/W4387674115","https://openalex.org/W4391469341","https://openalex.org/W4391843865","https://openalex.org/W4392393056","https://openalex.org/W4396580222","https://openalex.org/W4396829599","https://openalex.org/W4399670327","https://openalex.org/W4399859752","https://openalex.org/W4402501111","https://openalex.org/W4403883054","https://openalex.org/W4404077202","https://openalex.org/W6639055396","https://openalex.org/W6726873649","https://openalex.org/W6730323794","https://openalex.org/W6738989757","https://openalex.org/W6739901393","https://openalex.org/W6779940601"],"related_works":["https://openalex.org/W1840542775","https://openalex.org/W2416830231","https://openalex.org/W4405776396","https://openalex.org/W3003578468","https://openalex.org/W2336657400","https://openalex.org/W2088351705","https://openalex.org/W179926425","https://openalex.org/W2551532359","https://openalex.org/W4392964369","https://openalex.org/W2086883243"],"abstract_inverted_index":{"Positive":[0],"and":[1,7,22,38,54,60,64,80,139,154,179,199],"negative":[2],"association":[3],"prediction":[4,122,220],"between":[5,52,137],"gene":[6,53],"phenotype":[8],"helps":[9],"to":[10,67,70,109,118,131,147,166,176,185,214],"illustrate":[11],"the":[12,43,49,68,133,168,173,187,206,219,225],"underlying":[13,134],"mechanism":[14],"of":[15,25,189,221,232],"complex":[16],"traits":[17],"in":[18,32,47,191,224],"organisms.":[19],"The":[20,202,229],"transcription":[21],"regulation":[23],"activity":[24],"specific":[26],"genes":[27,138],"will":[28],"be":[29],"adjusted":[30],"accordingly":[31],"different":[33],"cell":[34],"types,":[35],"developmental":[36],"timepoints,":[37],"physiological":[39],"states.":[40],"There":[41],"are":[42,62,145],"following":[44],"two":[45,98,149,174],"problems":[46],"obtaining":[48],"positive/negative":[50],"associations":[51,136],"phenotype:":[55],"(1)":[56],"high-throughput":[57],"DNA/RNA":[58],"sequencing":[59],"phenotyping":[61],"expensive":[63],"time-consuming":[65],"due":[66],"need":[69],"process":[71],"large":[72],"sample":[73],"sizes;":[74],"(2)":[75],"experiments":[76,184],"introduce":[77],"both":[78,152],"random":[79],"systematic":[81],"errors,":[82],"and,":[83],"meanwhile,":[84],"calculations":[85],"or":[86,90],"predictions":[87],"using":[88],"software":[89],"models":[91],"may":[92],"produce":[93],"noise.":[94,181],"To":[95],"address":[96],"these":[97],"issues,":[99],"we":[100],"propose":[101],"a":[102,126,158],"Contrastive":[103],"Signed":[104],"Graph":[105],"Diffusion":[106],"Network,":[107],"CSGDN,":[108],"learn":[110],"robust":[111],"node":[112,169],"representations":[113],"with":[114],"fewer":[115],"training":[116],"samples":[117],"achieve":[119],"higher":[120],"link":[121,222],"accuracy.":[123],"CSGDN":[124,190],"uses":[125],"signed":[127],"graph":[128],"diffusion":[129],"method":[130],"uncover":[132],"regulatory":[135],"phenotypes.":[140],"Then,":[141],"stochastic":[142],"perturbation":[143],"strategies":[144],"used":[146],"create":[148],"views":[150,175],"for":[151,218],"original":[153],"diffusive":[155],"graphs.":[156],"Lastly,":[157],"multiview":[159],"contrastive":[160],"learning":[161],"paradigm":[162],"loss":[163],"is":[164,235],"designed":[165],"unify":[167],"presentations":[170],"learned":[171],"from":[172],"resist":[177],"interference":[178],"reduce":[180],"We":[182],"perform":[183],"validate":[186],"performance":[188],"three":[192],"crop":[193],"datasets:":[194],"Gossypium":[195],"hirsutum,":[196],"Brassica":[197],"napus,":[198],"Triticum":[200],"turgidum.":[201],"results":[203],"show":[204],"that":[205],"proposed":[207],"model":[208,234],"outperforms":[209],"state-of-the-art":[210],"methods":[211],"by":[212],"up":[213],"9.":[215],"28%":[216],"AUC":[217],"sign":[223],"G.":[226],"hirsutum":[227],"dataset.":[228],"source":[230],"code":[231],"our":[233],"available":[236],"at":[237],"https://github.com/Erican-Ji/CSGDN.":[238]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-04-14T08:04:32.555800","created_date":"2025-10-10T00:00:00"}