{"id":"https://openalex.org/W4407196554","doi":"https://doi.org/10.1093/bib/bbaf003","title":"A multi-modal fusion model with enhanced feature representation for chronic kidney disease progression prediction","display_name":"A multi-modal fusion model with enhanced feature representation for chronic kidney disease progression prediction","publication_year":2024,"publication_date":"2024-11-22","ids":{"openalex":"https://openalex.org/W4407196554","doi":"https://doi.org/10.1093/bib/bbaf003","pmid":"https://pubmed.ncbi.nlm.nih.gov/39913621"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaf003","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf003","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbaf003","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076759043","display_name":"Yixuan Qiao","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yixuan Qiao","raw_affiliation_strings":["Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100626225","display_name":"Hong Zhou","orcid":"https://orcid.org/0000-0002-7550-5033"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hong Zhou","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037930344","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-7699-2507"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102967572","display_name":"Ruixuan Chen","orcid":"https://orcid.org/0000-0002-2925-9484"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Ruixuan Chen","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055632609","display_name":"Xiaodong Zhang","orcid":"https://orcid.org/0000-0002-7940-802X"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Xiaodong Zhang","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018917778","display_name":"Sheng Nie","orcid":"https://orcid.org/0000-0002-8267-7909"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Sheng Nie","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025161064","display_name":"Fan Fan Hou","orcid":"https://orcid.org/0000-0003-3117-7418"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Fan Fan Hou","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000991048","display_name":"Yi Zhao","orcid":"https://orcid.org/0000-0001-6046-8420"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Zhao","raw_affiliation_strings":["Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,"],"raw_orcid":"https://orcid.org/0000-0001-6046-8420","affiliations":[{"raw_affiliation_string":"Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037645443","display_name":"Xin Xu","orcid":"https://orcid.org/0000-0002-6324-5211"},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I4210126592","display_name":"National Clinical Research","ror":"https://ror.org/03ddkvp86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210126592"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Xin Xu","raw_affiliation_strings":["National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , No. 1838 Guangzhou North Avenue, Baiyun District, Guangzhou 510515 ,","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I4210126592","https://openalex.org/I58200834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010222360","display_name":"Lianhe Zhao","orcid":"https://orcid.org/0000-0002-7736-2443"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianhe Zhao","raw_affiliation_strings":["Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,"],"raw_orcid":"https://orcid.org/0000-0002-7736-2443","affiliations":[{"raw_affiliation_string":"Institute of Computing Technology , Chinese Academy of Sciences (ICT), 6 Kexueyuan Nanlu, Zhongguancun, Haidian, Beijing 100190 ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , No. 1 Yanqihu East Rd, Huairou District, Beijing 101408 ,","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":2.9161,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.9202057,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"26","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7301350235939026},{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.7137941122055054},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6629778146743774},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6010292768478394},{"id":"https://openalex.org/keywords/modal","display_name":"Modal","score":0.5465604066848755},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4693979322910309},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4347786009311676},{"id":"https://openalex.org/keywords/feature-learning","display_name":"Feature learning","score":0.4313100278377533},{"id":"https://openalex.org/keywords/modality","display_name":"Modality (human\u2013computer interaction)","score":0.4198911488056183},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.41023150086402893}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7301350235939026},{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.7137941122055054},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6629778146743774},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6010292768478394},{"id":"https://openalex.org/C71139939","wikidata":"https://www.wikidata.org/wiki/Q910194","display_name":"Modal","level":2,"score":0.5465604066848755},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4693979322910309},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4347786009311676},{"id":"https://openalex.org/C59404180","wikidata":"https://www.wikidata.org/wiki/Q17013334","display_name":"Feature learning","level":2,"score":0.4313100278377533},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.4198911488056183},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.41023150086402893},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbaf003","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf003","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39913621","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39913621","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11801269","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11801269","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11801269/pdf/bbaf003.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbaf003","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbaf003","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1244370109","display_name":null,"funder_award_id":"92474204","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3487017088","display_name":null,"funder_award_id":"2021YFC2500203","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3557109126","display_name":null,"funder_award_id":"2021YFC2500203","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G5480111801","display_name":null,"funder_award_id":"32341019","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7536392352","display_name":null,"funder_award_id":"32070670","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W184318730","https://openalex.org/W1802508672","https://openalex.org/W1990540788","https://openalex.org/W2022182182","https://openalex.org/W2027952464","https://openalex.org/W2035017828","https://openalex.org/W2039427330","https://openalex.org/W2069943653","https://openalex.org/W2072948437","https://openalex.org/W2098124630","https://openalex.org/W2101252880","https://openalex.org/W2114252283","https://openalex.org/W2153987547","https://openalex.org/W2155965977","https://openalex.org/W2165439323","https://openalex.org/W2165817472","https://openalex.org/W2234357320","https://openalex.org/W2315849185","https://openalex.org/W2608146344","https://openalex.org/W2911907767","https://openalex.org/W2963090248","https://openalex.org/W2968264383","https://openalex.org/W2972604213","https://openalex.org/W2995674241","https://openalex.org/W3001004552","https://openalex.org/W3011235844","https://openalex.org/W3016279669","https://openalex.org/W3046618188","https://openalex.org/W3081103314","https://openalex.org/W3083804574","https://openalex.org/W3113903706","https://openalex.org/W3123809016","https://openalex.org/W3199658097","https://openalex.org/W3205594709","https://openalex.org/W4206406527","https://openalex.org/W4211210745","https://openalex.org/W4224947621","https://openalex.org/W4283645969","https://openalex.org/W4286697731","https://openalex.org/W4291021272","https://openalex.org/W4293476620","https://openalex.org/W4310948559","https://openalex.org/W4365135654","https://openalex.org/W4365443248","https://openalex.org/W4379530909","https://openalex.org/W4380319195","https://openalex.org/W4380887729","https://openalex.org/W4385405616","https://openalex.org/W4386090669","https://openalex.org/W4387503523","https://openalex.org/W4388523508","https://openalex.org/W4391659877","https://openalex.org/W4392145600","https://openalex.org/W4392777592","https://openalex.org/W4394855233","https://openalex.org/W4399138329","https://openalex.org/W4399418656","https://openalex.org/W4400274374","https://openalex.org/W4400324640","https://openalex.org/W4400776379","https://openalex.org/W4400897393"],"related_works":["https://openalex.org/W2905433371","https://openalex.org/W2888392564","https://openalex.org/W4310278675","https://openalex.org/W4388422664","https://openalex.org/W627697492","https://openalex.org/W2905271011","https://openalex.org/W3164948662","https://openalex.org/W4289536128","https://openalex.org/W3153597579","https://openalex.org/W4298151006"],"abstract_inverted_index":{"Artificial":[0],"intelligence":[1],"(AI)-based":[2],"multi-modal":[3,23,79,186],"fusion":[4,30,80,121],"algorithms":[5,183],"are":[6],"pivotal":[7],"in":[8,76],"emulating":[9],"clinical":[10,84,152],"practice":[11],"by":[12,46],"integrating":[13],"data":[14,187],"from":[15],"diverse":[16],"sources.":[17],"However,":[18],"most":[19],"of":[20,35,122,131,135,148,181,192],"the":[21,43,50,145,170,179,190],"existing":[22],"models":[24],"focus":[25,100],"on":[26,101,140],"designing":[27],"new":[28],"modal":[29,47],"methods,":[31],"ignoring":[32],"critical":[33],"role":[34],"feature":[36,39,70,103,117],"representation.":[37,106],"Enhancing":[38],"representativeness":[40],"can":[41,115],"address":[42],"noise":[44],"caused":[45],"heterogeneity":[48],"at":[49],"source,":[51],"enabling":[52],"high":[53],"performance":[54],"even":[55],"with":[56,67,98],"small":[57],"datasets":[58],"and":[59,90,96,105,124,157,165,188],"simple":[60],"architectures.":[61],"Here,":[62],"we":[63],"introduce":[64],"DeepOmix-FLEX":[65],"(Fusion":[66],"Learning":[68],"Enhanced":[69],"representation":[71],"for":[72,133],"X-modal":[73],"or":[74],"FLEX":[75,107,126,177],"short),":[77],"a":[78,99,109,128],"model":[81,161],"that":[82,114],"integrates":[83],"data,":[85,87,89],"proteomic":[86],"metabolomic":[88],"pathology":[91],"images":[92],"across":[93],"different":[94],"scales":[95],"modalities,":[97],"advanced":[102],"learning":[104],"contains":[108],"Feature":[110],"Encoding":[111],"Trainer":[112],"structure":[113],"train":[116],"encoding,":[118],"thus":[119],"achieving":[120],"inter-feature":[123],"inter-modal.":[125],"achieves":[127],"mean":[129,146],"AUC":[130,147],"0.887":[132],"prediction":[134],"chronic":[136],"kidney":[137],"disease":[138],"progression":[139],"an":[141],"internal":[142],"dataset,":[143],"exceeding":[144],"0.727":[149],"using":[150],"conventional":[151],"variables.":[153],"Following":[154],"external":[155],"validation":[156],"interpretability":[158],"analyses,":[159],"our":[160],"demonstrated":[162],"favorable":[163],"generalizability":[164],"validity,":[166],"as":[167,169],"well":[168],"ability":[171],"to":[172,184],"exploit":[173],"markers.":[174],"In":[175],"summary,":[176],"highlights":[178],"potential":[180],"AI":[182],"integrate":[185],"optimize":[189],"allocation":[191],"healthcare":[193],"resources":[194],"through":[195],"accurate":[196],"prediction.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}