{"id":"https://openalex.org/W4403603440","doi":"https://doi.org/10.1093/bib/bbae528","title":"A two-task predictor for discovering phase separation proteins and their undergoing mechanism","display_name":"A two-task predictor for discovering phase separation proteins and their undergoing mechanism","publication_year":2024,"publication_date":"2024-09-23","ids":{"openalex":"https://openalex.org/W4403603440","doi":"https://doi.org/10.1093/bib/bbae528","pmid":"https://pubmed.ncbi.nlm.nih.gov/39434494"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbae528","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae528","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbae528","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112985522","display_name":"Yetong Zhou","orcid":null},"institutions":[{"id":"https://openalex.org/I43313876","display_name":"Dalian Maritime University","ror":"https://ror.org/002b7nr53","country_code":"CN","type":"education","lineage":["https://openalex.org/I43313876"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yetong Zhou","raw_affiliation_strings":["School of Science, Dalian Maritime University , 1 Linghai Road, Dalian, 116026 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Science, Dalian Maritime University , 1 Linghai Road, Dalian, 116026 ,","institution_ids":["https://openalex.org/I43313876"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088314609","display_name":"Shengming Zhou","orcid":"https://orcid.org/0000-0003-1809-4415"},"institutions":[{"id":"https://openalex.org/I2802805919","display_name":"Science North","ror":"https://ror.org/028k36c88","country_code":"CA","type":"archive","lineage":["https://openalex.org/I2802805919"]},{"id":"https://openalex.org/I47689461","display_name":"Northeast Forestry University","ror":"https://ror.org/02yxnh564","country_code":"CN","type":"education","lineage":["https://openalex.org/I47689461"]}],"countries":["CA","CN"],"is_corresponding":false,"raw_author_name":"Shengming Zhou","raw_affiliation_strings":["College of Computer and Control Engineering, Northeast Forestry University , No. 26 Hexing Road, Xiangfang District, Harbin, 150040 ,","College of Life Science, Northeast Forestry University , No. 26 Hexing Road, Xiangfang District, Harbin, 150040 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Computer and Control Engineering, Northeast Forestry University , No. 26 Hexing Road, Xiangfang District, Harbin, 150040 ,","institution_ids":["https://openalex.org/I47689461"]},{"raw_affiliation_string":"College of Life Science, Northeast Forestry University , No. 26 Hexing Road, Xiangfang District, Harbin, 150040 ,","institution_ids":["https://openalex.org/I2802805919","https://openalex.org/I47689461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009378480","display_name":"Yue Bi","orcid":"https://orcid.org/0009-0001-6220-7475"},"institutions":[{"id":"https://openalex.org/I3018882396","display_name":"Victor (Japan)","ror":"https://ror.org/04b0q3m21","country_code":"JP","type":"company","lineage":["https://openalex.org/I3018882396"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU","JP"],"is_corresponding":false,"raw_author_name":"Yue Bi","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Monash University , Melbourne, Victora 3800 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Monash University , Melbourne, Victora 3800 ,","institution_ids":["https://openalex.org/I3018882396","https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017426085","display_name":"Quan Zou","orcid":"https://orcid.org/0000-0001-6406-1142"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quan Zou","raw_affiliation_strings":["Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China , No. 2006, Xiyuan Ave, West Hi-Tech Zone, Chengdu, 611731 ,"],"raw_orcid":"https://orcid.org/0000-0001-6406-1142","affiliations":[{"raw_affiliation_string":"Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China , No. 2006, Xiyuan Ave, West Hi-Tech Zone, Chengdu, 611731 ,","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066126756","display_name":"Cangzhi Jia","orcid":"https://orcid.org/0000-0002-4682-2881"},"institutions":[{"id":"https://openalex.org/I43313876","display_name":"Dalian Maritime University","ror":"https://ror.org/002b7nr53","country_code":"CN","type":"education","lineage":["https://openalex.org/I43313876"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cangzhi Jia","raw_affiliation_strings":["School of Science, Dalian Maritime University , 1 Linghai Road, Dalian, 116026 ,"],"raw_orcid":"https://orcid.org/0000-0002-4682-2881","affiliations":[{"raw_affiliation_string":"School of Science, Dalian Maritime University , 1 Linghai Road, Dalian, 116026 ,","institution_ids":["https://openalex.org/I43313876"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":1.1524,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.77560391,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"25","issue":"6","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6610584259033203},{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.56400066614151},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5342259407043457},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.4929215908050537},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.4708371162414551},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.4243469834327698},{"id":"https://openalex.org/keywords/compartmentalization","display_name":"Compartmentalization (fire protection)","score":0.4213941693305969},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.4107726812362671},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4002128839492798},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.39314383268356323},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29248595237731934},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09021958708763123},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08112680912017822}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6610584259033203},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.56400066614151},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5342259407043457},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.4929215908050537},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4708371162414551},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.4243469834327698},{"id":"https://openalex.org/C110455231","wikidata":"https://www.wikidata.org/wiki/Q897788","display_name":"Compartmentalization (fire protection)","level":3,"score":0.4213941693305969},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4107726812362671},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4002128839492798},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.39314383268356323},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29248595237731934},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09021958708763123},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08112680912017822},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000091582","descriptor_name":"Biomolecular Condensates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000095496","descriptor_name":"Phase Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095496","descriptor_name":"Phase Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095496","descriptor_name":"Phase Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095496","descriptor_name":"Phase Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbae528","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae528","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39434494","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39434494","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11492799","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11492799","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11492799/pdf/bbae528.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbae528","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae528","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5457985118","display_name":"\u6606\u866bRNA\u5e72\u6270\u7684dsRNA\u5206\u5b50\u8bbe\u8ba1\u53ca\u4ee3\u8c22\u52a8\u529b\u5b66\u7814\u7a76","funder_award_id":"62071079","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1689711448","https://openalex.org/W1975304761","https://openalex.org/W2043308634","https://openalex.org/W2043338013","https://openalex.org/W2051210555","https://openalex.org/W2076742999","https://openalex.org/W2079735306","https://openalex.org/W2097606916","https://openalex.org/W2101234009","https://openalex.org/W2119693327","https://openalex.org/W2139995722","https://openalex.org/W2155488238","https://openalex.org/W2156125289","https://openalex.org/W2156465034","https://openalex.org/W2168639701","https://openalex.org/W2425405879","https://openalex.org/W2461977200","https://openalex.org/W2568226856","https://openalex.org/W2590568317","https://openalex.org/W2599716733","https://openalex.org/W2605907842","https://openalex.org/W2612935389","https://openalex.org/W2743471889","https://openalex.org/W2786469974","https://openalex.org/W2789237874","https://openalex.org/W2810866092","https://openalex.org/W2884082692","https://openalex.org/W2909409778","https://openalex.org/W2939777553","https://openalex.org/W2962949934","https://openalex.org/W2967960129","https://openalex.org/W2969743565","https://openalex.org/W2980646921","https://openalex.org/W2991067665","https://openalex.org/W3017333675","https://openalex.org/W3020886002","https://openalex.org/W3035241254","https://openalex.org/W3039241573","https://openalex.org/W3112123143","https://openalex.org/W3130281988","https://openalex.org/W3143253488","https://openalex.org/W3191096373","https://openalex.org/W3199970975","https://openalex.org/W4205392984","https://openalex.org/W4212848381","https://openalex.org/W4281613736","https://openalex.org/W4282918068","https://openalex.org/W4291991763","https://openalex.org/W4292730936","https://openalex.org/W4296779471","https://openalex.org/W4308370073","https://openalex.org/W4323808718","https://openalex.org/W4376959496","https://openalex.org/W4382363582","https://openalex.org/W4385794403","https://openalex.org/W4386083644","https://openalex.org/W4393189158","https://openalex.org/W4393410976","https://openalex.org/W4399272959","https://openalex.org/W6675354045"],"related_works":["https://openalex.org/W4234653771","https://openalex.org/W4226193002","https://openalex.org/W4306938366","https://openalex.org/W2026670093","https://openalex.org/W2048904889","https://openalex.org/W2040958228","https://openalex.org/W2378211422","https://openalex.org/W1990340848","https://openalex.org/W3177737022","https://openalex.org/W4321353415"],"abstract_inverted_index":{"Liquid-liquid":[0],"phase":[1,39,55,179,196],"separation":[2,40,56,197],"(LLPS)":[3],"is":[4,34,105,113],"one":[5],"of":[6,12,30,67,154,194],"the":[7,10,27,38,87,116,139,155,188,192],"mechanisms":[8],"mediating":[9],"compartmentalization":[11],"macromolecules":[13],"(proteins":[14],"and":[15,42,58,75,95,143,163,191],"nucleic":[16],"acids)":[17],"in":[18,164,178],"cells,":[19],"forming":[20],"biomolecular":[21],"condensates":[22],"or":[23],"membraneless":[24],"organelles.":[25],"Consequently,":[26],"systematic":[28],"identification":[29],"potential":[31,54,195],"LLPS":[32,110,189],"proteins":[33,57],"crucial":[35],"for":[36],"understanding":[37],"process":[41],"its":[43,129],"biological":[44],"mechanisms.":[45],"A":[46],"two-task":[47],"predictor,":[48],"Opt_PredLLPS,":[49],"was":[50,157,168],"developed":[51],"to":[52,107,120,126,131,170],"discover":[53],"further":[59],"evaluate":[60],"their":[61],"mechanism.":[62],"The":[63,134,152],"first":[64],"task":[65,118,136],"model":[66,119,137,156],"Opt_PredLLPS":[68],"combines":[69],"a":[70,82,103,148,175],"convolutional":[71],"neural":[72],"network":[73],"(CNN)":[74],"bidirectional":[76],"long":[77],"short-term":[78],"memory":[79],"(BiLSTM)":[80],"through":[81],"fully":[83],"connected":[84],"layer,":[85],"where":[86],"CNN":[88],"utilizes":[89,97],"evolutionary":[90],"information":[91],"features":[92,99],"as":[93,100],"input,":[94],"BiLSTM":[96],"multimodal":[98],"input.":[101],"If":[102],"protein":[104,124],"predicted":[106],"be":[108],"an":[109],"protein,":[111],"it":[112],"input":[114],"into":[115],"second":[117,135],"predict":[121],"whether":[122],"this":[123],"needs":[125],"interact":[127],"with":[128],"partners":[130],"undergo":[132],"LLPS.":[133],"employs":[138],"XGBoost":[140],"classification":[141],"algorithm":[142],"37":[144],"physicochemical":[145],"properties":[146],"following":[147],"three-step":[149],"feature":[150],"selection.":[151],"effectiveness":[153],"validated":[158],"on":[159,187],"multiple":[160],"benchmark":[161],"datasets,":[162],"silico":[165],"saturation":[166],"mutagenesis":[167],"used":[169],"identify":[171],"regions":[172],"that":[173],"play":[174],"key":[176],"role":[177],"separation.":[180],"These":[181],"findings":[182],"may":[183],"assist":[184],"future":[185],"research":[186],"mechanism":[190],"discovery":[193],"proteins.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}