{"id":"https://openalex.org/W4401516928","doi":"https://doi.org/10.1093/bib/bbae396","title":"Reconstruction of gene regulatory networks for <i>Caenorhabditis elegans</i> using tree-shaped gene expression data","display_name":"Reconstruction of gene regulatory networks for <i>Caenorhabditis elegans</i> using tree-shaped gene expression data","publication_year":2024,"publication_date":"2024-07-25","ids":{"openalex":"https://openalex.org/W4401516928","doi":"https://doi.org/10.1093/bib/bbae396","pmid":"https://pubmed.ncbi.nlm.nih.gov/39133097"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbae396","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae396","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/bib/bbae396","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111192102","display_name":"Yida Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yida Wu","raw_affiliation_strings":["School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018955596","display_name":"Da Zhou","orcid":"https://orcid.org/0000-0002-0272-6644"},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Da Zhou","raw_affiliation_strings":["School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102023951","display_name":"Jie Hu","orcid":"https://orcid.org/0000-0002-0597-4176"},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Hu","raw_affiliation_strings":["School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematical Sciences, Xiamen University , Zengcuo'an West Road, Siming District, Xiamen 361000 , China","institution_ids":["https://openalex.org/I191208505"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I191208505"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":0.1965,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.50443718,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"25","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.7254683971405029},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.6891254186630249},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6674294471740723},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5875179171562195},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.5754682421684265},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5681809186935425},{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.5026464462280273},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.48411688208580017},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4780590832233429},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.46128764748573303},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.44531092047691345},{"id":"https://openalex.org/keywords/boolean-network","display_name":"Boolean network","score":0.4291810095310211},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3892057538032532},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.3218589127063751},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24013468623161316},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1910267174243927},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.16925638914108276},{"id":"https://openalex.org/keywords/boolean-function","display_name":"Boolean function","score":0.0778687596321106}],"concepts":[{"id":"https://openalex.org/C2778944004","wikidata":"https://www.wikidata.org/wiki/Q91703","display_name":"Caenorhabditis elegans","level":3,"score":0.7254683971405029},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.6891254186630249},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6674294471740723},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5875179171562195},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5754682421684265},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5681809186935425},{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.5026464462280273},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48411688208580017},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4780590832233429},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.46128764748573303},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.44531092047691345},{"id":"https://openalex.org/C134444547","wikidata":"https://www.wikidata.org/wiki/Q585230","display_name":"Boolean network","level":3,"score":0.4291810095310211},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3892057538032532},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3218589127063751},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24013468623161316},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1910267174243927},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.16925638914108276},{"id":"https://openalex.org/C187455244","wikidata":"https://www.wikidata.org/wiki/Q942353","display_name":"Boolean function","level":2,"score":0.0778687596321106},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbae396","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae396","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39133097","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39133097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11318059","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11318059","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11318059/pdf/bbae396.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbae396","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae396","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7442085250","display_name":"\u57fa\u4e8e\u591a\u5c42\u6b21\u751f\u7269\u6570\u636e\u7684\u80bf\u7624\u7ec6\u80de\u5f02\u8d28\u6027\u6570\u5b66\u5efa\u6a21\u7814\u7a76","funder_award_id":"11971405","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G791525929","display_name":null,"funder_award_id":"20720230024","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321878","display_name":"Natural Science Foundation of Fujian Province","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1481919380","https://openalex.org/W1600339875","https://openalex.org/W1964262399","https://openalex.org/W1967894481","https://openalex.org/W1967934074","https://openalex.org/W1977869118","https://openalex.org/W1985164652","https://openalex.org/W1989952069","https://openalex.org/W1993418188","https://openalex.org/W1995894334","https://openalex.org/W1999974018","https://openalex.org/W2000396646","https://openalex.org/W2011272261","https://openalex.org/W2011628627","https://openalex.org/W2020999234","https://openalex.org/W2032272029","https://openalex.org/W2032630997","https://openalex.org/W2055234679","https://openalex.org/W2056760934","https://openalex.org/W2062029454","https://openalex.org/W2070799958","https://openalex.org/W2078734575","https://openalex.org/W2082590010","https://openalex.org/W2086680065","https://openalex.org/W2088925327","https://openalex.org/W2091733078","https://openalex.org/W2095585040","https://openalex.org/W2096182373","https://openalex.org/W2104854813","https://openalex.org/W2108480332","https://openalex.org/W2115552299","https://openalex.org/W2117398609","https://openalex.org/W2130937302","https://openalex.org/W2132663737","https://openalex.org/W2136683157","https://openalex.org/W2138309709","https://openalex.org/W2143044785","https://openalex.org/W2160754686","https://openalex.org/W2170174900","https://openalex.org/W2520902279","https://openalex.org/W2563312892","https://openalex.org/W2792457053","https://openalex.org/W2964689826","https://openalex.org/W3045153201","https://openalex.org/W3093053585","https://openalex.org/W3159699835","https://openalex.org/W3175752499","https://openalex.org/W4323313435","https://openalex.org/W4361017571","https://openalex.org/W4393950665","https://openalex.org/W6628887588","https://openalex.org/W6647985145","https://openalex.org/W6797786779"],"related_works":["https://openalex.org/W2330768201","https://openalex.org/W1422717320","https://openalex.org/W2794960257","https://openalex.org/W2108120899","https://openalex.org/W2128085946","https://openalex.org/W2349909726","https://openalex.org/W2802063128","https://openalex.org/W4385417763","https://openalex.org/W4319977964","https://openalex.org/W2099449343"],"abstract_inverted_index":{"Constructing":[0],"gene":[1,11,37,42,64,152,171,198],"regulatory":[2,38,153,172,184,199],"networks":[3,154],"is":[4,191,207,212],"a":[5,100,107],"widely":[6],"adopted":[7],"approach":[8,110],"for":[9,103,155],"investigating":[10],"regulation,":[12],"offering":[13],"diverse":[14],"applications":[15],"in":[16,175,186,204],"biology":[17],"and":[18,73,106,123],"medicine.":[19],"A":[20],"great":[21],"deal":[22],"of":[23,54,67,93,166,183,196],"research":[24],"focuses":[25],"on":[26,112,161],"using":[27],"time":[28,88,116],"series":[29],"data":[30,34,44,66,79,104],"or":[31,48],"single-cell":[32],"RNA-sequencing":[33],"to":[35,61,131],"infer":[36],"networks.":[39],"However,":[40],"such":[41,77],"expression":[43,65],"lack":[45],"either":[46],"cellular":[47,72],"temporal":[49,74],"information.":[50],"Fortunately,":[51],"the":[52,91,133,149,162,194,215],"advent":[53],"time-lapse":[55],"confocal":[56],"laser":[57],"microscopy":[58],"enables":[59],"biologists":[60],"obtain":[62,132],"tree-shaped":[63,78,164],"Caenorhabditis":[68,167],"elegans,":[69,168],"achieving":[70],"both":[71],"resolution.":[75],"Although":[76],"provide":[80],"abundant":[81],"knowledge,":[82],"they":[83],"pose":[84],"challenges":[85],"like":[86],"non-pairwise":[87],"series,":[89],"laying":[90],"inaccuracy":[92],"downstream":[94],"analysis.":[95],"To":[96],"address":[97],"this":[98],"issue,":[99],"comprehensive":[101],"framework":[102],"integration":[105],"novel":[108],"Bayesian":[109],"based":[111,160],"Boolean":[113,144],"network":[114,145],"with":[115],"delay":[117],"are":[118,129,158,179],"proposed.":[119],"The":[120],"pre-screening":[121],"process":[122],"Markov":[124],"Chain":[125],"Monte":[126],"Carlo":[127],"algorithm":[128],"applied":[130],"parameter":[134],"estimates.":[135],"Simulation":[136],"studies":[137,178],"show":[138],"that":[139,201],"our":[140],"method":[141],"outperforms":[142],"existing":[143],"inference":[146],"algorithms.":[147],"Leveraging":[148],"proposed":[150],"approach,":[151],"five":[156],"subtrees":[157,190],"reconstructed":[159],"real":[163],"datatsets":[165],"where":[169],"some":[170],"relationships":[173,185,200],"confirmed":[174],"previous":[176],"genetic":[177],"recovered.":[180],"Also,":[181],"heterogeneity":[182],"different":[187],"cell":[188],"lineage":[189],"detected.":[192],"Furthermore,":[193],"exploration":[195],"potential":[197],"bear":[202],"importance":[203],"human":[205],"diseases":[206],"undertaken.":[208],"All":[209],"source":[210],"code":[211],"available":[213],"at":[214],"GitHub":[216],"repository":[217],"https://github.com/edawu11/BBTD.git.":[218]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2024-08-13T00:00:00"}