{"id":"https://openalex.org/W4401200632","doi":"https://doi.org/10.1093/bib/bbae364","title":"Integrated multi-omics with machine learning to uncover the intricacies of kidney disease","display_name":"Integrated multi-omics with machine learning to uncover the intricacies of kidney disease","publication_year":2024,"publication_date":"2024-07-25","ids":{"openalex":"https://openalex.org/W4401200632","doi":"https://doi.org/10.1093/bib/bbae364","pmid":"https://pubmed.ncbi.nlm.nih.gov/39082652"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbae364","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae364","pdf_url":"https://academic.oup.com/bib/article-pdf/25/5/bbae364/58697402/bbae364.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bib/article-pdf/25/5/bbae364/58697402/bbae364.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104284338","display_name":"Xinze Liu","orcid":"https://orcid.org/0009-0009-5252-7668"},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinze Liu","raw_affiliation_strings":["Beijing University of Chinese Medicine , China-Japan Friendship Clinic Medical College, China"],"raw_orcid":"https://orcid.org/0009-0009-5252-7668","affiliations":[{"raw_affiliation_string":"Beijing University of Chinese Medicine , China-Japan Friendship Clinic Medical College, China","institution_ids":["https://openalex.org/I17747738","https://openalex.org/I2801051648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101339834","display_name":"Jingxuan Shi","orcid":null},"institutions":[{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingxuan Shi","raw_affiliation_strings":["China Japan Friendship Institute of Clinical Medicine Research , Department of Nephrology, China-Japan Friendship Hospital, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China Japan Friendship Institute of Clinical Medicine Research , Department of Nephrology, China-Japan Friendship Hospital, China","institution_ids":["https://openalex.org/I2801051648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017491281","display_name":"Yuanyuan Jiao","orcid":"https://orcid.org/0009-0000-7192-2676"},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanyuan Jiao","raw_affiliation_strings":["Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital , Department of Nephrology, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital , Department of Nephrology, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I2801228662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069102647","display_name":"Jiaqi An","orcid":"https://orcid.org/0000-0003-0272-0514"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaqi An","raw_affiliation_strings":["Peking University China-Japan Friendship School of Clinical Medicine , Department of Nephrology, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking University China-Japan Friendship School of Clinical Medicine , Department of Nephrology, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I2801051648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114201200","display_name":"Jingwei Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingwei Tian","raw_affiliation_strings":["China-Japan Friendship Hospital , Department of Nephrology, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China-Japan Friendship Hospital , Department of Nephrology, China","institution_ids":["https://openalex.org/I2801051648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115593943","display_name":"Yue Yang","orcid":"https://orcid.org/0000-0002-8270-9464"},"institutions":[{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Yang","raw_affiliation_strings":["China-Japan Friendship Hospital , Department of Nephrology, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China-Japan Friendship Hospital , Department of Nephrology, China","institution_ids":["https://openalex.org/I2801051648"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100643001","display_name":"Li Zhuo","orcid":"https://orcid.org/0000-0003-2028-6168"},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I2801051648","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801051648"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Zhuo","raw_affiliation_strings":["China-Japan Friendship Hospital , Department of Nephrology, China","Beijing University of Chinese Medicine, 100029 Beijing, China","Corresponding author. Department of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China; China-Japan Friendship Clinic Medical College,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China-Japan Friendship Hospital , Department of Nephrology, China","institution_ids":["https://openalex.org/I2801051648"]},{"raw_affiliation_string":"Beijing University of Chinese Medicine, 100029 Beijing, China","institution_ids":["https://openalex.org/I17747738"]},{"raw_affiliation_string":"Corresponding author. Department of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China; China-Japan Friendship Clinic Medical College,","institution_ids":["https://openalex.org/I2801051648"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100643001"],"corresponding_institution_ids":["https://openalex.org/I17747738","https://openalex.org/I2801051648"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":14.0349,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.99367095,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"25","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.9828000068664551,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.9828000068664551,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9703999757766724,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.9542999863624573,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6317182779312134},{"id":"https://openalex.org/keywords/omics","display_name":"Omics","score":0.4916749596595764},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.45786052942276},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42854470014572144},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4049784541130066},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3371080756187439},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2649520933628082},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21125993132591248},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1933598518371582},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.09104746580123901}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6317182779312134},{"id":"https://openalex.org/C157585117","wikidata":"https://www.wikidata.org/wiki/Q158666","display_name":"Omics","level":2,"score":0.4916749596595764},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45786052942276},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42854470014572144},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4049784541130066},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3371080756187439},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2649520933628082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21125993132591248},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1933598518371582},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09104746580123901}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095028","descriptor_name":"Multiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbae364","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae364","pdf_url":"https://academic.oup.com/bib/article-pdf/25/5/bbae364/58697402/bbae364.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39082652","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39082652","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11289682","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11289682","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11289682/pdf/bbae364.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbae364","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae364","pdf_url":"https://academic.oup.com/bib/article-pdf/25/5/bbae364/58697402/bbae364.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.47999998927116394,"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320335783","display_name":"China-Japan Friendship Hospital","ror":"https://ror.org/037cjxp13"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401200632.pdf"},"referenced_works_count":176,"referenced_works":["https://openalex.org/W1831050183","https://openalex.org/W1987380823","https://openalex.org/W2017952818","https://openalex.org/W2026274122","https://openalex.org/W2060427373","https://openalex.org/W2093192308","https://openalex.org/W2101234009","https://openalex.org/W2177870565","https://openalex.org/W2545234811","https://openalex.org/W2550535012","https://openalex.org/W2557738935","https://openalex.org/W2612467560","https://openalex.org/W2753444025","https://openalex.org/W2766367869","https://openalex.org/W2767257195","https://openalex.org/W2768054517","https://openalex.org/W2784499877","https://openalex.org/W2788271355","https://openalex.org/W2791971425","https://openalex.org/W2794521141","https://openalex.org/W2794885170","https://openalex.org/W2795687816","https://openalex.org/W2798012109","https://openalex.org/W2799619538","https://openalex.org/W2800186767","https://openalex.org/W2802272045","https://openalex.org/W2802729845","https://openalex.org/W2809363719","https://openalex.org/W2810689242","https://openalex.org/W2894064654","https://openalex.org/W2897257410","https://openalex.org/W2897782745","https://openalex.org/W2897996652","https://openalex.org/W2899978968","https://openalex.org/W2899995215","https://openalex.org/W2901597112","https://openalex.org/W2906295032","https://openalex.org/W2906428833","https://openalex.org/W2908860015","https://openalex.org/W2913967880","https://openalex.org/W2914038321","https://openalex.org/W2919089713","https://openalex.org/W2921468574","https://openalex.org/W2923237341","https://openalex.org/W2924762575","https://openalex.org/W2935098703","https://openalex.org/W2937346600","https://openalex.org/W2937443931","https://openalex.org/W2938497713","https://openalex.org/W2939354927","https://openalex.org/W2941112903","https://openalex.org/W2945032660","https://openalex.org/W2951934944","https://openalex.org/W2952527443","https://openalex.org/W2953532875","https://openalex.org/W2955557725","https://openalex.org/W2961091764","https://openalex.org/W2964696298","https://openalex.org/W2968526958","https://openalex.org/W2969528126","https://openalex.org/W2977233427","https://openalex.org/W2977933365","https://openalex.org/W2980972660","https://openalex.org/W2982274340","https://openalex.org/W2984306354","https://openalex.org/W2985868371","https://openalex.org/W2996599192","https://openalex.org/W2997404865","https://openalex.org/W2999044305","https://openalex.org/W3000043291","https://openalex.org/W3004068444","https://openalex.org/W3006104185","https://openalex.org/W3008209848","https://openalex.org/W3010221055","https://openalex.org/W3012707556","https://openalex.org/W3014372210","https://openalex.org/W3015113267","https://openalex.org/W3024234640","https://openalex.org/W3030555654","https://openalex.org/W3034550836","https://openalex.org/W3035564257","https://openalex.org/W3036487861","https://openalex.org/W3036816779","https://openalex.org/W3040054418","https://openalex.org/W3044041980","https://openalex.org/W3044350743","https://openalex.org/W3047439539","https://openalex.org/W3048873596","https://openalex.org/W3050508217","https://openalex.org/W3080446999","https://openalex.org/W3081607022","https://openalex.org/W3092440565","https://openalex.org/W3093926768","https://openalex.org/W3096353891","https://openalex.org/W3098674050","https://openalex.org/W3098949126","https://openalex.org/W3100342937","https://openalex.org/W3100967665","https://openalex.org/W3101210883","https://openalex.org/W3103014197","https://openalex.org/W3109171273","https://openalex.org/W3109682927","https://openalex.org/W3111857857","https://openalex.org/W3118823028","https://openalex.org/W3123168575","https://openalex.org/W3123522617","https://openalex.org/W3125269882","https://openalex.org/W3125488134","https://openalex.org/W3131178486","https://openalex.org/W3133661165","https://openalex.org/W3152371839","https://openalex.org/W3157419338","https://openalex.org/W3158263766","https://openalex.org/W3161176628","https://openalex.org/W3164839005","https://openalex.org/W3173795754","https://openalex.org/W3176619972","https://openalex.org/W3186505668","https://openalex.org/W3195038684","https://openalex.org/W3200602313","https://openalex.org/W3200707343","https://openalex.org/W3203586501","https://openalex.org/W3206507054","https://openalex.org/W3213224786","https://openalex.org/W3214112664","https://openalex.org/W3214280461","https://openalex.org/W4200095267","https://openalex.org/W4206790840","https://openalex.org/W4211146151","https://openalex.org/W4211162540","https://openalex.org/W4220685469","https://openalex.org/W4220743473","https://openalex.org/W4221029336","https://openalex.org/W4223603964","https://openalex.org/W4235893153","https://openalex.org/W4246303429","https://openalex.org/W4281634119","https://openalex.org/W4282935130","https://openalex.org/W4283031510","https://openalex.org/W4283032464","https://openalex.org/W4283208985","https://openalex.org/W4285077432","https://openalex.org/W4290768853","https://openalex.org/W4292121951","https://openalex.org/W4293039403","https://openalex.org/W4293354575","https://openalex.org/W4294106961","https://openalex.org/W4295741152","https://openalex.org/W4308074414","https://openalex.org/W4308147354","https://openalex.org/W4312114404","https://openalex.org/W4321370754","https://openalex.org/W4322768301","https://openalex.org/W4327947056","https://openalex.org/W4366405447","https://openalex.org/W4367172326","https://openalex.org/W4384816663","https://openalex.org/W4385338552","https://openalex.org/W4385515928","https://openalex.org/W4386860582","https://openalex.org/W4389174422","https://openalex.org/W4389338208","https://openalex.org/W4391311657","https://openalex.org/W4391880483","https://openalex.org/W4392966950","https://openalex.org/W4393098522","https://openalex.org/W4394979394","https://openalex.org/W4398254956","https://openalex.org/W6675354045","https://openalex.org/W6743978227","https://openalex.org/W6755706301","https://openalex.org/W6766007511","https://openalex.org/W6771536673","https://openalex.org/W6791237859","https://openalex.org/W6859440066","https://openalex.org/W6868019769"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W3046775127","https://openalex.org/W3107602296","https://openalex.org/W4394896187","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W4364306694","https://openalex.org/W4312192474","https://openalex.org/W4283697347"],"abstract_inverted_index":{"The":[0],"development":[1],"of":[2,13,26,46,60,122,134,146],"omics":[3],"technologies":[4],"has":[5],"driven":[6],"a":[7,31,58,69],"profound":[8],"expansion":[9],"in":[10,20,125],"the":[11,17,24,47,130,144],"scale":[12],"biological":[14,40],"data":[15,95],"and":[16,37,57,80,84,119,132,149],"increased":[18],"complexity":[19,145],"internal":[21],"dimensions,":[22],"prompting":[23],"utilization":[25],"machine":[27],"learning":[28],"(ML)":[29],"as":[30],"powerful":[32],"toolkit":[33],"for":[34,71,92],"extracting":[35],"knowledge":[36],"understanding":[38,115],"underlying":[39],"patterns.":[41],"Kidney":[42],"disease":[43,107,116,148],"represents":[44],"one":[45],"major":[48],"growing":[49],"global":[50],"health":[51],"threats":[52],"with":[53,96],"intricate":[54],"pathogenic":[55],"mechanisms":[56],"lack":[59],"precise":[61],"molecular":[62,78,117],"pathology-based":[63],"therapeutic":[64],"modalities.":[65],"Accordingly,":[66],"there":[67],"is":[68,138],"need":[70],"advanced":[72],"high-throughput":[73],"approaches":[74],"to":[75,89,110,140],"capture":[76],"implicit":[77],"features":[79],"complement":[81],"current":[82,135],"experiments":[83],"statistics.":[85],"This":[86],"review":[87],"aims":[88],"delineate":[90],"strategies":[91],"integrating":[93],"multi-omics":[94],"appropriate":[97],"ML":[98],"methods,":[99],"highlighting":[100],"key":[101],"clinical":[102,151],"translational":[103],"scenarios,":[104],"including":[105],"predicting":[106],"progression":[108],"risks":[109],"improve":[111],"medical":[112],"decision-making,":[113],"comprehensively":[114],"mechanisms,":[118],"practical":[120],"applications":[121],"image":[123],"recognition":[124],"renal":[126],"digital":[127],"pathology.":[128],"Examining":[129],"benefits":[131],"challenges":[133],"integration":[136],"efforts":[137],"expected":[139],"shed":[141],"light":[142],"on":[143],"kidney":[147],"advance":[150],"practice.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":5}],"updated_date":"2026-07-25T09:21:30.201066","created_date":"2025-10-10T00:00:00"}