{"id":"https://openalex.org/W4394728974","doi":"https://doi.org/10.1093/bib/bbae154","title":"TripHLApan: predicting HLA molecules binding peptides based on triple coding matrix and transfer learning","display_name":"TripHLApan: predicting HLA molecules binding peptides based on triple coding matrix and transfer learning","publication_year":2024,"publication_date":"2024-03-27","ids":{"openalex":"https://openalex.org/W4394728974","doi":"https://doi.org/10.1093/bib/bbae154","pmid":"https://pubmed.ncbi.nlm.nih.gov/38600667"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbae154","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae154","pdf_url":"https://academic.oup.com/bib/article-pdf/25/3/bbae154/57189155/bbae154.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bib/article-pdf/25/3/bbae154/57189155/bbae154.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100377181","display_name":"Meng Wang","orcid":"https://orcid.org/0000-0002-6626-8857"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng Wang","raw_affiliation_strings":["School of Computer Science and engineering, Central South University , Changsha 410083 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and engineering, Central South University , Changsha 410083 , China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089984487","display_name":"Chuqi Lei","orcid":"https://orcid.org/0009-0007-5234-9924"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuqi Lei","raw_affiliation_strings":["School of Computer Science and engineering, Central South University , Changsha 410083 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and engineering, Central South University , Changsha 410083 , China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438360","display_name":"Jianxin Wang","orcid":"https://orcid.org/0000-0003-1516-0480"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Wang","raw_affiliation_strings":["School of Computer Science and engineering, Central South University , Changsha 410083 , China"],"raw_orcid":"https://orcid.org/0000-0003-1516-0480","affiliations":[{"raw_affiliation_string":"School of Computer Science and engineering, Central South University , Changsha 410083 , China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079316675","display_name":"Yaohang Li","orcid":"https://orcid.org/0000-0003-0178-1876"},"institutions":[{"id":"https://openalex.org/I81365321","display_name":"Old Dominion University","ror":"https://ror.org/04zjtrb98","country_code":"US","type":"education","lineage":["https://openalex.org/I81365321"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yaohang Li","raw_affiliation_strings":["Department of Computer Science, Old Dominion University , Norfolk, VA 23529 , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Old Dominion University , Norfolk, VA 23529 , USA","institution_ids":["https://openalex.org/I81365321"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100719013","display_name":"Min Li","orcid":"https://orcid.org/0000-0002-0188-1394"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min Li","raw_affiliation_strings":["School of Computer Science and engineering, Central South University , Changsha 410083 , China"],"raw_orcid":"https://orcid.org/0000-0002-0188-1394","affiliations":[{"raw_affiliation_string":"School of Computer Science and engineering, Central South University , Changsha 410083 , China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100719013"],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":2.1515,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.87602434,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"25","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-leukocyte-antigen","display_name":"Human leukocyte antigen","score":0.6601171493530273},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5564784407615662},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5472542643547058},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.5323818922042847},{"id":"https://openalex.org/keywords/transfer-of-learning","display_name":"Transfer of learning","score":0.48320329189300537},{"id":"https://openalex.org/keywords/preprocessor","display_name":"Preprocessor","score":0.41922715306282043},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.41342487931251526},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2726552486419678},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.260730504989624},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1395416259765625},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.0909382700920105}],"concepts":[{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.6601171493530273},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5564784407615662},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5472542643547058},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.5323818922042847},{"id":"https://openalex.org/C150899416","wikidata":"https://www.wikidata.org/wiki/Q1820378","display_name":"Transfer of learning","level":2,"score":0.48320329189300537},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.41922715306282043},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41342487931251526},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2726552486419678},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.260730504989624},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1395416259765625},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0909382700920105}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019496","descriptor_name":"Cancer Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bib/bbae154","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae154","pdf_url":"https://academic.oup.com/bib/article-pdf/25/3/bbae154/57189155/bbae154.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:38600667","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38600667","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11006794","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11006794","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11006794/pdf/bbae154.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.odu.edu:computerscience_fac_pubs-1326","is_oa":true,"landing_page_url":"https://digitalcommons.odu.edu/computerscience_fac_pubs/321","pdf_url":null,"source":{"id":"https://openalex.org/S4377196314","display_name":"ODU Digital Commons (Old Dominion University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I81365321","host_organization_name":"Old Dominion University","host_organization_lineage":["https://openalex.org/I81365321"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computer Science Faculty Publications","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1093/bib/bbae154","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbae154","pdf_url":"https://academic.oup.com/bib/article-pdf/25/3/bbae154/57189155/bbae154.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6100000143051147,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G4043378463","display_name":null,"funder_award_id":"61832019","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321514","display_name":"Central South University","ror":"https://ror.org/00f1zfq44"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4394728974.pdf"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1614298861","https://openalex.org/W1981106544","https://openalex.org/W1994048581","https://openalex.org/W2000305183","https://openalex.org/W2053707749","https://openalex.org/W2073621589","https://openalex.org/W2099500226","https://openalex.org/W2101375662","https://openalex.org/W2110694683","https://openalex.org/W2112752664","https://openalex.org/W2122779464","https://openalex.org/W2141059167","https://openalex.org/W2142739377","https://openalex.org/W2149350146","https://openalex.org/W2154509769","https://openalex.org/W2157331557","https://openalex.org/W2170853242","https://openalex.org/W2271526964","https://openalex.org/W2271914738","https://openalex.org/W2332626020","https://openalex.org/W2471645096","https://openalex.org/W2555228033","https://openalex.org/W2615065404","https://openalex.org/W2743893844","https://openalex.org/W2781173963","https://openalex.org/W2783102765","https://openalex.org/W2890016602","https://openalex.org/W2898389621","https://openalex.org/W2911188335","https://openalex.org/W2947980028","https://openalex.org/W2949949116","https://openalex.org/W2950373774","https://openalex.org/W2952230511","https://openalex.org/W2952607757","https://openalex.org/W2963347351","https://openalex.org/W2967717440","https://openalex.org/W2979293383","https://openalex.org/W2979882137","https://openalex.org/W2983176158","https://openalex.org/W2995389725","https://openalex.org/W2995494055","https://openalex.org/W3024570138","https://openalex.org/W3039313607","https://openalex.org/W3042452836","https://openalex.org/W3042910002","https://openalex.org/W3083537918","https://openalex.org/W3111171798","https://openalex.org/W3112376646","https://openalex.org/W3122375914","https://openalex.org/W3128687311","https://openalex.org/W3129412675","https://openalex.org/W3134347364","https://openalex.org/W3159316433","https://openalex.org/W3159962684","https://openalex.org/W3198814330","https://openalex.org/W4206904133","https://openalex.org/W4220655797","https://openalex.org/W4366085055","https://openalex.org/W4385245566","https://openalex.org/W6636510571","https://openalex.org/W6683738474","https://openalex.org/W6739901393","https://openalex.org/W6753075380","https://openalex.org/W6807638256"],"related_works":["https://openalex.org/W2389214306","https://openalex.org/W4235240664","https://openalex.org/W2965083567","https://openalex.org/W1838576100","https://openalex.org/W2095886385","https://openalex.org/W2889616422","https://openalex.org/W2089704382","https://openalex.org/W1983399550","https://openalex.org/W97075385","https://openalex.org/W2357523926"],"abstract_inverted_index":{"Human":[0],"leukocyte":[1],"antigen":[2],"(HLA)":[3],"recognizes":[4],"foreign":[5],"threats":[6],"and":[7,24,73,88,98,109,129,166,191,201,214,240],"triggers":[8],"immune":[9],"responses":[10],"by":[11,64],"presenting":[12],"peptides":[13,63,243],"to":[14,42,112,119],"T":[15],"cells.":[16],"Computationally":[17],"modeling":[18],"the":[19,30,80,93,103,107,113,120,130,135,154,170,175,199,219,236,245],"binding":[20,47,62,99,145,215,237],"patterns":[21],"between":[22,85,95],"peptide":[23],"HLA":[25,45,60,86,96],"is":[26,37,230,251],"very":[27],"important":[28],"for":[29,58,234,244],"development":[31],"of":[32,127,149,156,203,221,238,247],"tumor":[33,248],"vaccines.":[34,249],"However,":[35],"it":[36],"still":[38],"a":[39,54,222,231],"big":[40],"challenge":[41],"accurately":[43],"predict":[44],"molecules":[46,61,87],"peptides.":[48],"In":[49,195],"this":[50],"paper,":[51],"we":[52,105,197],"develop":[53],"new":[55],"model":[56,167],"TripHLApan":[57,139,179,229,250],"predicting":[59,235],"integrating":[65],"triple":[66],"coding":[67,110],"matrix,":[68],"BiGRU":[69,136],"+":[70],"Attention":[71],"models,":[72,178],"transfer":[74,150],"learning":[75,151],"strategy.":[76],"We":[77],"have":[78],"found":[79],"main":[81],"interaction":[82],"site":[83],"regions":[84],"peptides,":[89],"as":[90,92],"well":[91],"correlation":[94],"encoding":[97],"motifs.":[100],"Based":[101],"on":[102,124,134],"discovery,":[104],"make":[106],"preprocessing":[108],"closer":[111],"natural":[114],"biological":[115],"process.":[116],"Besides,":[117],"due":[118],"input":[121],"being":[122],"based":[123],"multiple":[125],"types":[126],"features":[128],"attention":[131],"module":[132],"focused":[133],"hidden":[137],"layer,":[138],"has":[140],"learned":[141],"more":[142],"sequence":[143],"level":[144],"information.":[146],"The":[147,225],"application":[148],"strategies":[152],"ensures":[153],"accuracy":[155],"prediction":[157,186],"results":[158,226],"under":[159],"special":[160],"lengths":[161],"(peptides":[162],"in":[163,184,218],"length":[164],"8)":[165],"scalability":[168,202],"with":[169,174,188],"data":[171,210],"explosion.":[172],"Compared":[173],"current":[176],"optimal":[177],"exhibits":[180],"strong":[181],"predictive":[182,205],"performance":[183,206],"various":[185],"environments":[187],"different":[189],"positive":[190],"negative":[192],"sample":[193],"ratios.":[194],"addition,":[196],"validate":[198],"superiority":[200],"TripHLApan's":[204],"using":[207],"additional":[208],"latest":[209],"sets,":[211],"ablation":[212],"experiments":[213],"reconstitution":[216],"ability":[217],"samples":[220],"melanoma":[223],"patient.":[224],"show":[227],"that":[228],"powerful":[232],"tool":[233],"HLA-I":[239],"HLA-II":[241],"molecular":[242],"synthesis":[246],"publicly":[252],"available":[253],"at":[254],"https://github.com/CSUBioGroup/TripHLApan.git.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":4}],"updated_date":"2026-07-18T07:39:51.176621","created_date":"2025-10-10T00:00:00"}