{"id":"https://openalex.org/W4362731109","doi":"https://doi.org/10.1093/bib/bbad056","title":"FLAN: feature-wise latent additive neural models for biological applications","display_name":"FLAN: feature-wise latent additive neural models for biological applications","publication_year":2023,"publication_date":"2023-04-06","ids":{"openalex":"https://openalex.org/W4362731109","doi":"https://doi.org/10.1093/bib/bbad056","pmid":"https://pubmed.ncbi.nlm.nih.gov/37031956"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbad056","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbad056","pdf_url":"https://academic.oup.com/bib/advance-article-pdf/doi/10.1093/bib/bbad056/49789121/bbad056.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bib/advance-article-pdf/doi/10.1093/bib/bbad056/49789121/bbad056.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081134111","display_name":"An-phi Nguyen","orcid":"https://orcid.org/0000-0003-4998-5931"},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210126328","display_name":"IBM Research - Zurich","ror":"https://ror.org/02js37d36","country_code":"CH","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115","https://openalex.org/I4210126328"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"An-Phi Nguyen","raw_affiliation_strings":["ETH Z\u00fcrich Department of Mathematics, , R\u00e4mistrasse 101, 8092 Z\u00fcrich , Switzerland","IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland"],"affiliations":[{"raw_affiliation_string":"ETH Z\u00fcrich Department of Mathematics, , R\u00e4mistrasse 101, 8092 Z\u00fcrich , Switzerland","institution_ids":["https://openalex.org/I35440088"]},{"raw_affiliation_string":"IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland","institution_ids":["https://openalex.org/I4210126328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016137369","display_name":"Stefania Vasilaki","orcid":null},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210126328","display_name":"IBM Research - Zurich","ror":"https://ror.org/02js37d36","country_code":"CH","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115","https://openalex.org/I4210126328"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Stefania Vasilaki","raw_affiliation_strings":["ETH Z\u00fcrich Department of Mathematics, , R\u00e4mistrasse 101, 8092 Z\u00fcrich , Switzerland","IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland"],"affiliations":[{"raw_affiliation_string":"ETH Z\u00fcrich Department of Mathematics, , R\u00e4mistrasse 101, 8092 Z\u00fcrich , Switzerland","institution_ids":["https://openalex.org/I35440088"]},{"raw_affiliation_string":"IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland","institution_ids":["https://openalex.org/I4210126328"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016524881","display_name":"Mar\u00eda Rodr\u00edguez Mart\u00ednez","orcid":"https://orcid.org/0000-0003-3766-4233"},"institutions":[{"id":"https://openalex.org/I4210126328","display_name":"IBM Research - Zurich","ror":"https://ror.org/02js37d36","country_code":"CH","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115","https://openalex.org/I4210126328"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Mar\u00eda Rodr\u00edguez Mart\u00ednez","raw_affiliation_strings":["IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland"],"affiliations":[{"raw_affiliation_string":"IBM Research Europe , S\u00e4umerstrasse 4, 8803 R\u00fcschlikon, Z\u00fcrich , Switzerland","institution_ids":["https://openalex.org/I4210126328"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5016524881","https://openalex.org/A5081134111"],"corresponding_institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4210126328"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":{"value":4011,"currency":"USD","value_usd":4011},"fwci":1.2075,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.82608596,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"24","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12535","display_name":"Machine Learning and Data Classification","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.8173933625221252},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7068380117416382},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.7030426263809204},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.6008490920066833},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.505007803440094},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4901362359523773},{"id":"https://openalex.org/keywords/constraint","display_name":"Constraint (computer-aided design)","score":0.48609423637390137},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.46547266840934753},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.4621034860610962},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.4148770868778229},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.32442203164100647},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12154066562652588}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.8173933625221252},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7068380117416382},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.7030426263809204},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.6008490920066833},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.505007803440094},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4901362359523773},{"id":"https://openalex.org/C2776036281","wikidata":"https://www.wikidata.org/wiki/Q48769818","display_name":"Constraint (computer-aided design)","level":2,"score":0.48609423637390137},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.46547266840934753},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.4621034860610962},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.4148770868778229},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.32442203164100647},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12154066562652588},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/bib/bbad056","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbad056","pdf_url":"https://academic.oup.com/bib/advance-article-pdf/doi/10.1093/bib/bbad056/49789121/bbad056.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37031956","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37031956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10199769","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10199769","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10199769/pdf/bbad056.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},{"id":"pmh:oai:www.research-collection.ethz.ch:20.500.11850/613521","is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.11850/613521","pdf_url":null,"source":{"id":"https://openalex.org/S4306402302","display_name":"Repository for Publications and Research Data (ETH Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I35440088","host_organization_name":"ETH Zurich","host_organization_lineage":["https://openalex.org/I35440088"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Briefings in Bioinformatics, 24 (3)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"doi:10.3929/ethz-b-000613521","is_oa":true,"landing_page_url":"https://doi.org/10.3929/ethz-b-000613521","pdf_url":null,"source":{"id":"https://openalex.org/S7407051236","display_name":"ETH Z\u00fcrich Research Collection","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1093/bib/bbad056","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbad056","pdf_url":"https://academic.oup.com/bib/advance-article-pdf/doi/10.1093/bib/bbad056/49789121/bbad056.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.800000011920929,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[{"id":"https://openalex.org/G5451116430","display_name":null,"funder_award_id":"826121","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G675428038","display_name":null,"funder_award_id":"826121","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G8318064016","display_name":null,"funder_award_id":"Horizon","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4362731109.pdf"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W64048259","https://openalex.org/W1869789329","https://openalex.org/W1903748367","https://openalex.org/W1986962710","https://openalex.org/W2101449057","https://openalex.org/W2103496339","https://openalex.org/W2123174628","https://openalex.org/W2133610914","https://openalex.org/W2137983211","https://openalex.org/W2148143831","https://openalex.org/W2171893470","https://openalex.org/W2194775991","https://openalex.org/W2318459925","https://openalex.org/W2334354575","https://openalex.org/W2552396116","https://openalex.org/W2560674852","https://openalex.org/W2747329762","https://openalex.org/W2787894218","https://openalex.org/W2809671526","https://openalex.org/W2913668833","https://openalex.org/W2913954081","https://openalex.org/W2945976633","https://openalex.org/W2951506174","https://openalex.org/W2951513593","https://openalex.org/W2962851944","https://openalex.org/W2963716183","https://openalex.org/W2964024268","https://openalex.org/W2964907782","https://openalex.org/W2973631113","https://openalex.org/W2976174503","https://openalex.org/W2979330275","https://openalex.org/W2999729612","https://openalex.org/W3078644326","https://openalex.org/W3123497755","https://openalex.org/W3128426437","https://openalex.org/W3131457744","https://openalex.org/W3160037564","https://openalex.org/W3160420762","https://openalex.org/W3163411042","https://openalex.org/W3211008974","https://openalex.org/W4236137412","https://openalex.org/W4238143865","https://openalex.org/W4254345397","https://openalex.org/W4287718305","https://openalex.org/W4288627909","https://openalex.org/W4301409532","https://openalex.org/W4310895557","https://openalex.org/W4317436377","https://openalex.org/W4321611068","https://openalex.org/W6602558931","https://openalex.org/W6662026312","https://openalex.org/W6685133223","https://openalex.org/W6687483927","https://openalex.org/W6729822694","https://openalex.org/W6730035438","https://openalex.org/W6734194636","https://openalex.org/W6736518430","https://openalex.org/W6737947904","https://openalex.org/W6739901393","https://openalex.org/W6745359453","https://openalex.org/W6748218292","https://openalex.org/W6748600614","https://openalex.org/W6753001334","https://openalex.org/W6759055035","https://openalex.org/W6763002979","https://openalex.org/W6766263406","https://openalex.org/W6766511095","https://openalex.org/W6767007542","https://openalex.org/W6767857164","https://openalex.org/W6776595772","https://openalex.org/W6781148700","https://openalex.org/W6804126845","https://openalex.org/W6820010905"],"related_works":["https://openalex.org/W4385957992","https://openalex.org/W4229079080","https://openalex.org/W4206534706","https://openalex.org/W4385965371","https://openalex.org/W4386025632","https://openalex.org/W4321648797","https://openalex.org/W2984803561","https://openalex.org/W3006943036","https://openalex.org/W2970447476","https://openalex.org/W3163334550"],"abstract_inverted_index":{"Code":[0],"and":[1],"example":[2],"data":[3],"are":[4],"available":[5],"at":[6],"https://github.com/phineasng/flan_bio.":[7]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}